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Extract from the Register of European Patents

EP About this file: EP0630246

EP0630246 - ESTROGEN/PROGESTIN/ANTIPROGESTIN METHOD AND KIT FOR ORAL CONTRACEPTION AND REGULATING MENSES [Right-click to bookmark this link]
StatusNo opposition filed within time limit
Status updated on  22.05.2009
Database last updated on 12.07.2024
Most recent event   Tooltip17.06.2011Lapse of the patent in a contracting state
New state(s): GR, LU
published on 20.07.2011  [2011/29]
Applicant(s)For all designated states
Eastern Virginia Medical School
721 Fairfax Avenue
Norfolk, VA 23507-2000 / US
[2007/16]
Former [1994/52]For all designated states
SCHERING AKTIENGESELLSCHAFT
Müllerstrasse 170/178
D-13353 Berlin / DE
Inventor(s)01 / HODGEN, Gary D.
619 Mowbray Arch
Norfolk, VA 23501 / US
02 / CHWALISZ, Krzysztof
Lobber Steig 7a
D-13505 Berlin / DE
[1994/52]
Representative(s)Schrell, Andreas, et al
Gleiss Große Schrell und Partner mbB
Patentanwälte Rechtsanwälte
Leitzstrasse 45
70469 Stuttgart / DE
[N/P]
Former [2008/03]Schrell, Andreas, et al
Gleiss Grosse Schrell & Partner Patentanwälte Rechtsanwälte Leitzstrasse 45
70469 Stuttgart / DE
Former [2007/16]Gleiss & Grosse
Patentanwälte Rechtsanwälte Leitzstrasse 45
70469 Stuttgart / DE
Application number, filing date93907185.802.03.1993
[1994/52]
WO1993US01931
Priority number, dateUS1992084305802.03.1992         Original published format: US 843058
[1994/52]
Filing languageEN
Procedural languageEN
PublicationType: A1 Application with search report
No.:WO9317686
Date:16.09.1993
Language:EN
[1993/22]
Type: A1 Application with search report 
No.:EP0630246
Date:28.12.1994
Language:EN
The application published by WIPO in one of the EPO official languages on 16.09.1993 takes the place of the publication of the European patent application.
[1994/52]
Type: B1 Patent specification 
No.:EP0630246
Date:16.07.2008
Language:EN
[2008/29]
Search report(s)International search report - published on:US16.09.1993
(Supplementary) European search report - dispatched on:EP31.05.2002
ClassificationIPC:A61K31/565
[2002/28]
CPC:
A61K31/565 (EP,US); A61P15/00 (EP); A61P15/12 (EP);
A61P15/18 (EP); A61P5/18 (EP)
C-Set:
A61K31/565, A61K2300/00 (US,EP);
A61K31/565, A61K31/565, A61K31/565 (EP,US)
Former IPC [1994/52]A61K31/56
Designated contracting statesAT,   BE,   CH,   DE,   DK,   ES,   FR,   GB,   GR,   IE,   IT,   LI,   LU,   MC,   NL,   PT,   SE [1994/52]
TitleGerman:VERFAHREN UNTER VERWENDUNG VON ÖSTROGEN/PROGESTIN/ANTIPROGESTIN UND VORRICHTUNG ZUR ORALEN KONTRAZEPTION UND ZUR REGULATION DER MENSTRUATION[1994/52]
English:ESTROGEN/PROGESTIN/ANTIPROGESTIN METHOD AND KIT FOR ORAL CONTRACEPTION AND REGULATING MENSES[1994/52]
French:PROCEDE PAR STROGENE/PROGESTERONE/ANTIPROGESTERONE, KIT POUR CONTRACEPTION ORALE ET REGULATION DES REGLES[1994/52]
Entry into regional phase30.09.1994National basic fee paid 
30.09.1994Search fee paid 
30.09.1994Designation fee(s) paid 
30.09.1994Examination fee paid 
Examination procedure04.10.1993Request for preliminary examination filed
International Preliminary Examining Authority: FR
30.09.1994Examination requested  [1994/52]
15.01.2003Despatch of a communication from the examining division (Time limit: M04)
27.06.2003Despatch of communication that the application is deemed to be withdrawn, reason: reply to the communication from the examining division not received in time
27.08.2003Reply to a communication from the examining division
12.05.2004Despatch of a communication from the examining division (Time limit: M06)
17.11.2004Reply to a communication from the examining division
10.02.2006Despatch of a communication from the examining division (Time limit: M04)
17.05.2006Reply to a communication from the examining division
26.01.2007Despatch of a communication from the examining division (Time limit: M04)
10.05.2007Reply to a communication from the examining division
15.11.2007Communication of intention to grant the patent
22.03.2008Fee for grant paid
22.03.2008Fee for publishing/printing paid
Opposition(s)17.04.2009No opposition filed within time limit [2009/26]
Request for further processing for:27.08.2003Request for further processing filed
27.08.2003Full payment received (date of receipt of payment)
Request granted
17.03.2004Decision despatched
Fees paidRenewal fee
15.02.1995Renewal fee patent year 03
14.02.1996Renewal fee patent year 04
13.02.1997Renewal fee patent year 05
16.02.1998Renewal fee patent year 06
12.02.1999Renewal fee patent year 07
18.02.2000Renewal fee patent year 08
16.02.2001Renewal fee patent year 09
14.02.2002Renewal fee patent year 10
14.02.2003Renewal fee patent year 11
13.02.2004Renewal fee patent year 12
15.02.2005Renewal fee patent year 13
15.02.2006Renewal fee patent year 14
08.02.2007Renewal fee patent year 15
11.01.2008Renewal fee patent year 16
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competence of the Unified
Patent Court
See the Register of the Unified Patent Court for opt-out data
Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court.
Lapses during opposition  TooltipAT16.07.2008
BE16.07.2008
DK16.07.2008
IT16.07.2008
SE16.10.2008
GR17.10.2008
ES27.10.2008
PT16.12.2008
LU02.03.2009
MC31.03.2009
[2011/25]
Former [2010/19]AT16.07.2008
BE16.07.2008
DK16.07.2008
IT16.07.2008
SE16.10.2008
ES27.10.2008
PT16.12.2008
MC31.03.2009
Former [2010/05]AT16.07.2008
BE16.07.2008
DK16.07.2008
IT16.07.2008
ES27.10.2008
PT16.12.2008
MC31.03.2009
Former [2009/19]AT16.07.2008
BE16.07.2008
DK16.07.2008
ES27.10.2008
PT16.12.2008
Former [2009/15]AT16.07.2008
ES27.10.2008
PT16.12.2008
Former [2009/09]ES27.10.2008
PT16.12.2008
Documents cited:Search[Y]EP0129499  (SCHERING AG [DE]) [Y] 1-22 * abstract * * page 2, paragraph 2 * * example C on; page 3, paragraph 4 *;
 [DY]EP0253607  (AMERICAN HOME PROD [US]) [DY] 1-22 * the whole document *;
 [X]  - HEALY D L, BAULIEU E E, HODGEN G D, "Induction of menses by an antiprogesterone steroid (RU 486) in primates: site of action, dose-response relationships, and hormonal effects", FERTILITY AND STERILITY, (1983), vol. 40, no. 2, pages 253 - 257, XP008002911 [X] 1-22 * the whole document *
 [Y]  - CHILLIK C F, HSIU J G, ACOSTA A A, VAN UEM J F H M, HODGEN G D, "RU486-induced menses in cynomolgus monkeys: uniformity of endometrial sloughing", FERTILITY AND STERILITY, (198605), vol. 45, no. 5, pages 708 - 712, XP001068224 [Y] 1-22 * abstract * * page 709, column 1, paragraph 2 * * page 710, column 2, paragraph 3 * * page 711, column 1, paragraph 3 *
 [Y]  - CROXATTO H B, SALVATIERRA A M, ROMERO C, SPITZ I M, "Late Luteal Phase Administration of RU486 for Three Successive Cycles Does Not Disrupt Bleeding Patterns or Ovulation", JOURNAL OF CLINICAL ENDOCRINOLOGY AND METABOLISM, (19871201), vol. 65, pages 1272 - 1277, XP008002486 [Y] 1-22 * abstract * * page 1, column 1 - column 2 * * page 1277, column 1 *
 [Y]  - SHORTLE B, DYRENFURTH I, FERIN M, "Effects of an Antiprogesterone Agent, RU-486, on the Menstrual Cycle of the Rhesus Monkey", JOURNAL OF CLINICAL ENDOCRINOLOGY AND METABOLISM, (198504), vol. 60, no. 4, pages 731 - 735, XP001068228 [Y] 1-22 * abstract * * page 733, column 2 *
 [Y]  - GARZO V G, LIU J, ULMANN A, BEAULIEU E, YEN S S C, "Effects of an Antiprogesterone (RU486) on the Hypothalamic-Hypophyseal-Ovarian-Endometrial Axis During the Luteal Phase of the Menstrual Cycle", JOURNAL OF ENDOCRINOLOGY AND METABOLISM, (1988), vol. 66, no. 3, pages 508 - 517, XP008002478 [Y] 1-22 * abstract * * page 512, column 2, paragraph 3 *
 [Y]  - NIEMAN L K, HEALY D L, SPITZ I M, MERRIAM G R, BARDIN C W, LORIAUX, D L, CHROUSOS G P, Use of Single Doses of the Antiprogesterone Steroid RU 486 for Induction of Menstruation in Normal Women, NEW YORK & LONDON, PLENUM PRESS, (1985), XP001076665 [Y] 1-22 * abstract * * page 282, paragraph 1 *
 [Y]  - PHILIBERT D, RU38486: An Original Multifaceted Antihormone in vivo, BERLIN, GERMANY, WALTER DE GRUYTER, (1984), XP008002479 [Y] 1-22 * in "Adrenal Steroid Antagonism", Agarwal MK (ed.); page 92, paragraph 5 - paragraph 6 *
 [Y]  - NIEMAN L K, CHOATE T M, CHROUSOS G P, HEALY D L, MORIN M, RENQUIST D, MERRIAM G R, SPITZ I M, BARDIN C W, BAULIEU E E, LORIAUX L L, "The Progesterone Antagonist RU 486", THE NEW ENGLAND JOURNAL OF MEDICINE, (19870122), vol. 316, no. 4, pages 187 - 191, XP000564124 [Y] 1-22 * page 188, column 2, paragraph 3 - page 189, column 1, paragraph 2 * * page 189, column 2, paragraph 5 - page 190, column 1, paragraph 1 *
 [Y]  - SHOUPE D, MISHELL D R, LAHTEENMAKI P, HEIKINHEIMO O, BIRGERSON L, MADKOUR H, SPITZ I M, "Effects of the antiprogesterone RU 486 in normal women", AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY, (198712), vol. 157, pages 1415 - 1420, XP008002485 [Y] 1-22 * abstract * * page 1416, column 2, paragraph 3 * * page 1417, column 2, paragraph 3 *
 [Y]  - ZAHRADNIK H P, NEULEN J, BRECKWOLDT M, "Antigestagene - Grundlagen und Klinik", ARCHIVES OF GYNECOLOGY AND OBSTETRICS, (1991), vol. 250, no. 1, pages 861 - 868, XP008002752 [Y] 1-22 * abstract * * figure 1 * * page 866, paragraph 9 *
 [Y]  - BAULIEU E E, ULMANN A, "Antiprogesterone activity of RU 486 and its contragestive and other applications", HUMAN REPRODUCTION, (1986), vol. 1, no. 2, pages 107 - 110, XP000564113 [Y] 1-22 * the whole document *
 [A]  - PARFITT K (ED.), Martindale - The complete drug reference, 32rd edition, LONDON, PHARMACEUTICAL PRESS, (1999), XP002198132 [A] 1-22 * page 1412, column 1 - column 2 * * page 1451, column 2 - column 3 * * page 1452, column 1 *
International search[Y]EP0253607  (AMERICAN HOME PROD [US]);
 [Y]  - CHEMICAL ABSTRACTS, Volume 105, No. 1, CHILLIK et al., "RU486-induced Manses in Cynomogus Monkeys in Uniformity of Endometrial Sloughing", Abstract No. 897; Fertil. Steril., 1986, 45(5), p. 708, 712, XP002955364
The EPO accepts no responsibility for the accuracy of data originating from other authorities; in particular, it does not guarantee that it is complete, up to date or fit for specific purposes.