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EP About this file: EP0643768

EP0643768 - OLIGONUCLEOTIDE SEQUENCES AND TRANSGENIC ANIMALS TRANSFECTED THEREWITH HAVING REDUCED SENSITIVITY TO NARCOTIC ANALGESICS [Right-click to bookmark this link]
Status	The application is deemed to be withdrawn Status updated on 05.02.1999 Database last updated on 03.09.2024
Most recent event Tooltip	05.02.1999	Application deemed to be withdrawn	published on 24.03.1999 [1999/12]
Applicant(s)	For all designated states DUZ PARTNERSHIP 1830 Funston Avenue San Francisco, CA 94166 / US
	[1995/12]
Inventor(s)	01 / LEE, Nancy, M. 1830 Funston Avenue San Francisco, CA 94116 / US
	02 / LOH, Horace, H. 54 Mendosa San Francisco, CA 94116 / US
	03 / LIPPMAN, David 1739 West Sonoma Avenue Stockton, CA 95204 / US
	[1995/12]
Representative(s)	Greaves, Carol Pauline Mewburn Ellis LLP 33 Gutter Lane London EC2V 8AS / GB
	[N/P]
Former [1995/12]	Greaves, Carol Pauline Mewburn Ellis York House 23 Kingsway London WC2B 6HP / GB
Application number, filing date	93912092.9	29.03.1993
	[1995/12]
	WO1993US02913
Priority number, date	US19920866677	10.04.1992 Original published format: US 866677
	[1995/12]
Filing language	EN
Procedural language	EN
Publication	Type:	A1 Application with search report
	No.:	WO9321309
	Date:	28.10.1993
	Language:	EN
	[1993/26]
	Type:	A1 Application with search report
	No.:	EP0643768
	Date:	22.03.1995
	Language:	EN
	The application published by WIPO in one of the EPO official languages on 28.10.1993 takes the place of the publication of the European patent application.
	[1995/12]
Search report(s)	International search report - published on:	US	28.10.1993
	(Supplementary) European search report - dispatched on:	EP	14.10.1996
Classification	IPC:	C12N15/00, C12N15/11, C07H15/12, C07H17/00, A61K31/70, A01K67/027, C12N5/10, C07K14/705	[1996/46]
	CPC:	C12N15/1138 (EP); A01K67/0275 (EP); C07K14/70503 (EP); C12N15/8509 (EP); A01K2217/05 (EP); A01K2227/105 (EP); (+) A01K2267/03 (EP) (-)
	Former IPC [1995/12]	C12N15/00, C07H15/12, C07H17/00, A61K31/70
Designated contracting states	AT, BE, CH, DE, DK, ES, FR, GB, GR, IE, IT, LI, LU, MC, NL, PT, SE [1995/12]
Title	German:	OLIGONUKLEOTIDSEQUENZEN UND TRANSGENE TIERE DIE DAMIT TRANSFEKTIERT WURDEN BESITZEN EINE REDUZIERTE SENSITIVITÄT GEGEN NARKKOTISCHE ANALGETIKA	[1995/12]
	English:	OLIGONUCLEOTIDE SEQUENCES AND TRANSGENIC ANIMALS TRANSFECTED THEREWITH HAVING REDUCED SENSITIVITY TO NARCOTIC ANALGESICS	[1995/12]
	French:	SEQUENCES D'OLIGONUCLEOTIDES ET ANIMAUX TRANSGENIQUES TRANSFECTES AVEC CELLES-CI ET PRESENTANT UNE SENSIBILITE REDUITE AUX ANALGESIQUES NARCOTIQUES	[1995/12]
Entry into regional phase	31.10.1994	National basic fee paid
	31.10.1994	Search fee paid
	31.10.1994	Designation fee(s) paid
	31.10.1994	Examination fee paid
Examination procedure	05.11.1993	Request for preliminary examination filed International Preliminary Examining Authority: US
	31.10.1994	Examination requested [1995/12]
	01.10.1998	Application deemed to be withdrawn, date of legal effect [1999/12]
	28.10.1998	Despatch of communication that the application is deemed to be withdrawn, reason: renewal fee not paid in time [1999/12]
Fees paid	Renewal fee
	20.02.1995	Renewal fee patent year 03
	26.02.1996	Renewal fee patent year 04
	24.02.1997	Renewal fee patent year 05
	Penalty fee
	Additional fee for renewal fee
	31.03.1998	06 M06 Not yet paid
Opt-out from the exclusive Tooltip competence of the Unified Patent Court	See the Register of the Unified Patent Court for opt-out data
	Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court.
Documents cited:	Search	[PA] - LIPPMAN, D.A. ET AL., "Opioid-binding cell adhesion molecule (OBCAM)-related clones from a rat brain cDNA library", GENE, AMSTERDAM NL, (19920815), vol. 117, no. 2, pages 249 - 254, XP000602047 [PA] 1 * the whole document * DOI: http://dx.doi.org/10.1016/0378-1119(92)90734-7
		[PX] - ANN D.K. ET AL., "Specific reduction of delta opioid receptor binding in transfected NG108-15 cells", JOURNAL OF BIOLOGICAL CHEMISTRY (MICROFILMS), MD US, (19920415), vol. 267, no. 11, pages 7921 - 7926, XP000602135 [PX] 9-19 * the whole document *
		[PX] - LANE, C.M. ET AL., "Regulation of an opioid-binding protein in NG108-15 cells parallels regulation of delta opioid receptors", PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF USA, WASHINGTON US, (19921201), vol. 89, no. 23, pages 11234 - 11238, XP000602145 [PX] 9-19 * the whole document * DOI: http://dx.doi.org/10.1073/pnas.89.23.11234
		[T] - GOVITRAPONG, P. ET AL., "Transfection of NG108-15 cells with antisense opioid-binding cell adhesion molecule cDNA alters opioid receptor G-protein interaction", JOURNAL OF BIOLOGICAL CHEMISTRY (MICROFILMS), MD US, (19930825), vol. 268, no. 24, pages 18280 - 18285, XP000602144 [T] 9-19 * the whole document *
		[T] - CHAKRABORTI, A. ET AL., "Genetic mapping of opioid binding protein gene(s) to mouse chromosome 9", MAMMALIAN GENOME, (1993), vol. 4, no. 3, pages 179 - 182, XP000602417 [T] 1 * the whole document * DOI: http://dx.doi.org/10.1007/BF00352235
	International search	[Y]US5087571
		[Y] - Advances in Genetics, Volume 24, issued 1987, G. SCANGOS et al., "Gene Transfer into Mice", pages 285-322, see entire document.
		[Y] - Proceedings National Academy of Sciences, Volume 78, No. 11, issued November 1981, S.V. SUGGS et al., "Use of Synthetic Oligonucleotides as Hybridization Probes: Isolation of Cloned cDNA Sequences for Human beta2-Microglobulin", pages 6613-6617, especially page 6613, col. 1, lines 9-22.
		[Y] - Proceedings of the National Academy of Sciences, Volume 83, issued June 1986, T.M. CHO et al., "Purification to Apparent Homogeneity of a mu-Type Opiod Receptor from Rat Brain", pages 4138-4142, see entire document.
		[Y] - Anti-Cancer Drug Design, Volume 2, issued 1987, P.S. MILLER et al., "A New Approach to Chemotherapy Based on Molecular Biology and Nucleic Acid Chemistry: Mutagen (Masking Tape for Gene Expression)", pages 117-123, see entire document.

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