EP0659408 - Use of R(+)alpha-lipoic acid, R-(-)dihydrolipoic and metabolites for the treatment of diabetes mellitus and its resulting disorders [Right-click to bookmark this link] | Status | Patent revoked Status updated on 10.04.2009 Database last updated on 02.09.2024 | Most recent event Tooltip | 10.04.2009 | Revocation of patent | published on 13.05.2009 [2009/20] | 10.04.2009 | Lapse of the patent in a contracting state | published on 13.05.2009 [2009/20] | Applicant(s) | For all designated states Evonik Degussa GmbH Rellinghauser Straße 1-11 45128 Essen / DE | [N/P] |
Former [2009/14] | For all designated states Evonik Degussa GmbH Rellinghauser Strasse 1-11 45128 Essen / DE | ||
Former [2007/47] | For all designated states Degussa GmbH Bennigsenplatz 1 40474 Düsseldorf / DE | ||
Former [2002/13] | For all designated states VIATRIS GmbH & Co. KG Weismüllerstrasse 45 60314 Frankfurt am Main / DE | ||
Former [2001/31] | For all designated states ASTA Medica Aktiengesellschaft An der Pikardie 10 01277 Dresden / DE | ||
Former [1995/26] | For all designated states ASTA Medica Aktiengesellschaft An der Pikardie 10 D-01277 Dresden / DE | Inventor(s) | 01 /
Wessel, Dr. Klaus Homburger Landstrasse 46c D-60435 Frankfurt / DE | 02 /
Borbe, Dr. Harald Im Borner Grund 87 D-55127 Mainz / DE | 03 /
Ulrich, Dr. Heinz Bayernstrasse 2 D-63843 Niedernberg / DE | 04 /
Hettche, Dr. Helmut Martinstrasse 23 D-63128 Dietzenbach / DE | 05 /
Bisswanger, Prof. Dr. Hans Lindenstrasse 31 D-72411 Bodelshausen / DE | 06 /
Packer, Prof. Dr. L. 64, Charles Hill Road Orinda, California 94563 / US | 07 /
Klip, Prof. Amira 33, Harbour Square apt. 1620 Toronto M5G 1x8 / CA | [1995/26] | Representative(s) | Godemeyer, Thomas, et al polypatent An den Gärten 7 51491 Overath / DE | [N/P] |
Former [2004/36] | Godemeyer, Thomas, Dr., et al Sternagel, Fleischer, Godemeyer & Partner Patentanwälte An den Gärten 7 51491 Overath / DE | ||
Former [2001/23] | Wibbelmann, Jobst, Dr., Dipl.-Chem., et al Wuesthoff & Wuesthoff, Patent- und Rechtsanwälte, Schweigerstrasse 2 81541 München / DE | Application number, filing date | 94120045.3 | 17.12.1994 | [1995/26] | Priority number, date | DE19934343593 | 21.12.1993 Original published format: DE 4343593 | [1995/26] | Filing language | DE | Procedural language | DE | Publication | Type: | A1 Application with search report | No.: | EP0659408 | Date: | 28.06.1995 | Language: | DE | [1995/26] | Type: | B1 Patent specification | No.: | EP0659408 | Date: | 01.08.2001 | Language: | DE | [2001/31] | Search report(s) | (Supplementary) European search report - dispatched on: | EP | 24.04.1995 | Classification | IPC: | A61K31/385 | [1995/26] | CPC: |
A61K31/385 (EP,US);
A61K31/19 (EP,US);
A61K31/22 (EP,US);
A61K31/355 (EP,US);
A61P3/08 (EP);
A61P3/10 (EP)
| Designated contracting states | AT, BE, CH, DE, DK, ES, FR, GB, GR, IE, IT, LI, LU, MC, NL, PT, SE [1995/26] | Title | German: | Verwendung von R-(+)alpha-Liponsäure, R(-)-Dihydroliponsäure und Metabolite zur Behandlung von Diabetes mellitus sowie seiner Folgeerkrankungen | [2000/38] | English: | Use of R(+)alpha-lipoic acid, R-(-)dihydrolipoic and metabolites for the treatment of diabetes mellitus and its resulting disorders | [1995/26] | French: | Utilisation de R(+)alpha acide loique, R(-)-acide dihydrolipoique et leurs metabolites pour le traitement de diabète et ses désordres secondaires | [1995/26] |
Former [1995/26] | Verwendung von R-(+)alpha-Liponsäure, R(-)-Dihydroliponsäure und Metabolite zur Behandlung von Diabetes mellitus sowie seiner Folge-erkrankungen | Examination procedure | 17.12.1994 | Examination requested [1995/26] | 29.06.1998 | Despatch of a communication from the examining division (Time limit: M08) | 05.02.1999 | Reply to a communication from the examining division | 11.01.2001 | Despatch of communication of intention to grant (Approval: Yes) | 08.02.2001 | Communication of intention to grant the patent | 01.03.2001 | Fee for grant paid | 01.03.2001 | Fee for publishing/printing paid | Divisional application(s) | EP99102285.6 / EP0958816 | Opposition(s) | Opponent(s) | 01
29.04.2002
17.05.2002
ADMISSIBLE Dr. Gerhard Mann Chem.-pharm. Fabrik GmbH Brunsbütteler Damm 165-173 D-13581 Berlin / DE Opponent's representative Maiwald, Walter, et al, et al Maiwald GmbH Elisenhof Elisenstraße 3 80335 München / DE | [N/P] |
Former [2008/39] | |||
Opponent(s) | 01
29.04.2002
17.05.2002
ADMISSIBLE Dr. Gerhard Mann Chem.-pharm. Fabrik GmbH Brunsbütteler Damm 165-173 D-13581 Berlin / DE Opponent's representative Maiwald, Walter, et al, et al Maiwald Patentanwalts GmbH Elisenhof Elisenstrasse 3 80335 München / DE | ||
Former [2007/07] | |||
Opponent(s) | 01
29.04.2002
17.05.2002
ADMISSIBLE Dr. Gerhard Mann Chem.-pharm. Fabrik GmbH Brunsbütteler Damm 165-173 D-13581 Berlin / DE Opponent's representative Maiwald, Walter, et al, et al Maiwald Patentanwalts GmbH Elisenhof Elisenstrasse 3 D-80335 München / DE | ||
Former [2002/26] | |||
Opponent(s) | 01
29.04.2002
Dr. Gerhard Mann Chem.-pharm. Fabrik GmbH Brunsbütteler Damm 165-173 D-13581 Berlin / DE Opponent's representative Maiwald, Walter, Dr. Dipl.-Chem, et al, et al Maiwald Patentanwalds GmbH Achenstrasse 43 40237 Düsseldorf / DE | 05.06.2002 | Invitation to proprietor to file observations on the notice of opposition | 03.02.2003 | Reply of patent proprietor to notice(s) of opposition | 25.03.2004 | Date of oral proceedings | 06.05.2004 | Despatch of minutes of oral proceedings | 06.05.2004 | Despatch of communication that the patent will be revoked | 06.11.2007 | Legal effect of revocation of patent [2009/20] | Appeal following opposition | 06.07.2004 | Appeal received No. T0857/04 | 13.09.2004 | Statement of grounds filed | 06.11.2007 | Result of appeal procedure: appeal of the proprietor was rejected | 06.11.2007 | Date of oral proceedings | Fees paid | Renewal fee | 23.12.1996 | Renewal fee patent year 03 | 10.12.1997 | Renewal fee patent year 04 | 30.11.1998 | Renewal fee patent year 05 | 09.12.1999 | Renewal fee patent year 06 | 12.12.2000 | Renewal fee patent year 07 |
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Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court. | Documents cited: | Search | [PX] - T. KAWABATA ET AL, "Alpha-lipoate can protect against glycation of serum albumin, but not low density lipoprotein.", BIOCHEM. BIOPHYS. RES. COMMUN., vol. 203, no. 1, pages 99 - 104, XP008036187 [PX] 4,5 * the whole document * DOI: http://dx.doi.org/10.1006/bbrc.1994.2154 | [PX] - C. BONAVENTURA ET AL, "In vitro action of the enantiomers of alpha-lipoic acid.", NAUNYN-SCHMIEDEBERGS ARCH. PHARMACOL, vol. 349, no. SUPL., page R8, XP002119387 [PX] 4,5 * the whole document * | [A] - J. JÖRG ET AL, "Zur medikamentösen Behandlung der diabetischen Polyneuropathie mit der Alpha-liponsäure oder Vitamin-B-Präparaten", NERVENARZT, vol. 59, no. 1, pages 36 - 44, XP002119388 | [A] - J. STUDT ET AL., "die diabetische autonome Neuropathie des Herzens und ihre Behandlung mit Thioctsäure.", DTSCH. ZSCHR. VERDAU. STOFFWECHSELKR., vol. 44, no. 4, pages 173 - 180, XP008036188 | [DA] - S.S. WAGH ET AL., "mode of action of lipoic acid in diabetes.", J. BIOSCI., vol. 11, no. 1-4, pages 59 - 74, XP008036199 DOI: http://dx.doi.org/10.1007/BF02704658 |