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Extract from the Register of European Patents

EP About this file: EP0726948

EP0726948 - METHOD OF INDUCING AND MAINTAINING NEURONAL CELLS [Right-click to bookmark this link]
StatusNo opposition filed within time limit
Status updated on  04.01.2008
Database last updated on 11.09.2024
Most recent event   Tooltip01.01.2010Lapse of the patent in a contracting state
New state(s): LU		published on 03.02.2010  [2010/05]
Applicant(s)For all designated states
President and Fellows of Harvard College
124 Mount Auburn Street
University Place
Fourth Floor South
Cambridge, Massachusetts 02138 / US
[N/P]
Former [2007/09]For all designated states
PRESIDENT AND FELLOWS OF HARVARD COLLEGE
124 Mount Auburn Street, University Place, Fourth Floor South
Cambridge, Massachusetts 02138 / US
Former [1996/34]For all designated states
PRESIDENT AND FELLOWS OF HARVARD COLLEGE
University Place, 4th floor South, 124 Mt. Aubern Street
Cambridge, MA 02138 / US
Inventor(s)01 / MELTON, Douglas, A.
22 Flocum Road
Lexington, MA 02173 / US
02 / HEMMATI-BRIVANLOU, Ali
325 East 84th Street
New York, NY 10028 / US
[1996/34]
Representative(s)Horner, Martin Grenville, et al
Marks & Clerk LLP
Aurora
120 Bothwell Street
Glasgow
G2 7JS / GB
[N/P]
Former [1996/34]Horner, Martin Grenville, et al
Cruikshank & Fairweather 19 Royal Exchange Square
Glasgow G1 3AE Scotland / GB
Application number, filing date94930791.214.10.1994
[1996/34]
WO1994US11745
Priority number, dateUS1993013674814.10.1993         Original published format: US 136748
[1996/34]
Filing languageEN
Procedural languageEN
PublicationType: A1 Application with search report
No.:WO9510611
Date:20.04.1995
Language:EN
[1995/17]
Type: A1 Application with search report 
No.:EP0726948
Date:21.08.1996
Language:EN
The application published by WIPO in one of the EPO official languages on 20.04.1995 takes the place of the publication of the European patent application.
[1996/34]
Type: B1 Patent specification 
No.:EP0726948
Date:28.02.2007
Language:EN
[2007/09]
Search report(s)International search report - published on:EP20.04.1995
ClassificationIPC:C12N15/12, A61K48/00, A61K38/18, C12N5/06, G01N33/50
[1996/34]
CPC:
C07K14/71 (EP,US); A61K31/17 (EP,US); A61K31/513 (EP,US);
A61K31/519 (EP,US); A61K31/7004 (EP,US); A61K31/7068 (EP,US);
A61K38/1841 (EP,US); A61K38/185 (EP,US); A61K38/1858 (EP,US);
A61K38/22 (EP,US); A61K38/57 (EP,US); A61P25/00 (EP);
A61P25/28 (EP); C07K14/46 (EP,US); C07K14/4702 (EP,US);
A61K38/00 (EP,US) (-)
C-Set:
A61K38/1841, A61K2300/00 (EP,US);
A61K38/1858, A61K2300/00 (US,EP);
A61K38/185, A61K2300/00 (US,EP);
A61K38/57, A61K2300/00 (US,EP)
Designated contracting statesAT,   BE,   CH,   DE,   DK,   ES,   FR,   GB,   GR,   IE,   IT,   LI,   LU,   MC,   NL,   PT,   SE [1996/34]
TitleGerman:VERFAHREN ZUR INDUZIERUNG UND ZUR ERHALTUNG NEURONALEN ZELLEN[1996/34]
English:METHOD OF INDUCING AND MAINTAINING NEURONAL CELLS[1996/34]
French:PROCEDE D'INDUCTION ET DE MAINTIEN DE CELLULES NEURONALES[1996/34]
Entry into regional phase01.05.1996National basic fee paid 
01.05.1996Designation fee(s) paid 
01.05.1996Examination fee paid 
Examination procedure11.05.1995Request for preliminary examination filed
International Preliminary Examining Authority: EP
01.05.1996Examination requested  [1996/34]
10.03.1999Despatch of a communication from the examining division (Time limit: M06)
25.10.1999Despatch of communication that the application is deemed to be withdrawn, reason: reply to the communication from the examining division not received in time
27.10.1999Reply to a communication from the examining division
28.05.2001Despatch of a communication from the examining division (Time limit: M06)
19.11.2001Reply to a communication from the examining division
08.07.2004Despatch of a communication from the examining division (Time limit: M06)
17.01.2005Reply to a communication from the examining division
14.02.2005Despatch of a communication from the examining division (Time limit: M04)
20.06.2005Reply to a communication from the examining division
01.08.2005Despatch of a communication from the examining division (Time limit: M05)
10.01.2006Reply to a communication from the examining division
15.02.2006Despatch of a communication from the examining division (Time limit: M02)
19.04.2006Reply to a communication from the examining division
14.08.2006Communication of intention to grant the patent
18.12.2006Fee for grant paid
18.12.2006Fee for publishing/printing paid
Opposition(s)29.11.2007No opposition filed within time limit [2008/06]
Request for further processing for:27.10.1999Request for further processing filed
01.11.1999Full payment received (date of receipt of payment)
Request granted
29.11.1999Decision despatched
Fees paidRenewal fee
16.09.1996Renewal fee patent year 03
26.09.1997Renewal fee patent year 04
21.09.1998Renewal fee patent year 05
20.09.1999Renewal fee patent year 06
22.09.2000Renewal fee patent year 07
22.10.2001Renewal fee patent year 08
21.10.2002Renewal fee patent year 09
23.10.2003Renewal fee patent year 10
25.10.2004Renewal fee patent year 11
27.10.2005Renewal fee patent year 12
27.10.2006Renewal fee patent year 13
Opt-out from the exclusive  Tooltip
competence of the Unified
Patent Court		 See the Register of the Unified Patent Court for opt-out data
Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court.
Lapses during opposition  TooltipAT28.02.2007
BE28.02.2007
CH28.02.2007
DK28.02.2007
FR28.02.2007
IT28.02.2007
LI28.02.2007
NL28.02.2007
GR29.05.2007
DE30.05.2007
SE31.05.2007
ES08.06.2007
PT30.07.2007
GB14.10.2007
LU14.10.2007
IE15.10.2007
MC31.10.2007
[2010/05]
Former [2009/03]AT28.02.2007
BE28.02.2007
CH28.02.2007
DK28.02.2007
FR28.02.2007
IT28.02.2007
LI28.02.2007
NL28.02.2007
GR29.05.2007
DE30.05.2007
SE31.05.2007
ES08.06.2007
PT30.07.2007
GB14.10.2007
IE15.10.2007
MC31.10.2007
Former [2008/52]AT28.02.2007
BE28.02.2007
CH28.02.2007
DK28.02.2007
FR28.02.2007
IT28.02.2007
LI28.02.2007
NL28.02.2007
GR29.05.2007
DE30.05.2007
SE31.05.2007
ES08.06.2007
PT30.07.2007
IE15.10.2007
MC31.10.2007
Former [2008/48]AT28.02.2007
BE28.02.2007
CH28.02.2007
DK28.02.2007
IT28.02.2007
LI28.02.2007
NL28.02.2007
GR29.05.2007
DE30.05.2007
SE31.05.2007
ES08.06.2007
PT30.07.2007
IE15.10.2007
FR19.10.2007
MC31.10.2007
Former [2008/26]AT28.02.2007
BE28.02.2007
CH28.02.2007
DK28.02.2007
IT28.02.2007
LI28.02.2007
NL28.02.2007
GR29.05.2007
DE30.05.2007
SE31.05.2007
ES08.06.2007
PT30.07.2007
FR19.10.2007
MC31.10.2007
Former [2008/23]AT28.02.2007
BE28.02.2007
CH28.02.2007
DK28.02.2007
IT28.02.2007
LI28.02.2007
NL28.02.2007
GR29.05.2007
DE30.05.2007
SE31.05.2007
ES08.06.2007
PT30.07.2007
FR19.10.2007
Former [2008/21]AT28.02.2007
BE28.02.2007
CH28.02.2007
DK28.02.2007
LI28.02.2007
NL28.02.2007
GR29.05.2007
DE30.05.2007
SE31.05.2007
ES08.06.2007
PT30.07.2007
Former [2008/12]AT28.02.2007
BE28.02.2007
CH28.02.2007
DK28.02.2007
LI28.02.2007
NL28.02.2007
DE30.05.2007
SE31.05.2007
ES08.06.2007
PT30.07.2007
Former [2008/05]AT28.02.2007
BE28.02.2007
CH28.02.2007
DK28.02.2007
LI28.02.2007
NL28.02.2007
SE31.05.2007
ES08.06.2007
PT30.07.2007
Cited inInternational search[X]  - A. HEMMATI-BRIVANLOU AND D.A. MELTON, "A truncated activin receptor inhibits mesoderm induction and formation of axial structures in Xenopus embryos", NATURE, (1992), vol. 359, pages 609 - 614 [X] 1-8,13-15,17,18,25,26,41-44 * see the whole document, especially the discussion. *
 [X]  - M. HASHIMOTO ET AL., "Follistatin is a developmentally regulated cytokine in neural differentiation", J. BIOL. CHEM., (1992), vol. 267, pages 7203 - 7206 [X] 1-4,17,18,25,26,41,42 * see the whole document. *
 [A]  - M. HASHIMOTO ET AL., "Activin/EDF as an inhibitor of neural differentiation", BIOCHEM. BIOPHYS. RES. COMMUN., (1990), vol. 173, pages 193 - 200 [A] 1 * see the abstract. *
 [PX]  - A. HEMMATI-BRIVANLOU AND D.A. MELTON, "Inhibition of activin receptor signaling promotes neuralization in Xenopus", CELL, (1994), vol. 77, pages 273 - 281 [PX] 1-6,13-15,17,18,25,26,41-44 * see the whole document. *
 [PX]  - A. HEMMATI-BRIVANLOU ET AL., "Follistatin, an antagonist of activin, is expressed in the Spemann organizer and displays direct neuralizing activity", CELL, (1994), vol. 77, pages 283 - 295 [PX] 1-4,14,15,17,18,25,26,41-44 * see the whole document. *
The EPO accepts no responsibility for the accuracy of data originating from other authorities; in particular, it does not guarantee that it is complete, up to date or fit for specific purposes.