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Extract from the Register of European Patents

EP About this file: EP0684230

EP0684230 - 4-£(R)-1'-formylethyl azetidin-2-one derivatives [Right-click to bookmark this link]
StatusNo opposition filed within time limit
Status updated on  09.05.2003
Database last updated on 03.10.2024
Most recent event   Tooltip09.05.2003No opposition filed within time limitpublished on 25.06.2003  [2003/26]
Applicant(s)For all designated states
Takasago International Corporation
37-1, Kamata 5-chome, Ohta-ku
Tokyo / JP
[N/P]
Former [1999/47]For all designated states
Takasago International Corporation
37-1, Kamata 5-chome, Ohta-ku
Tokyo / JP
Former [1995/48]For all designated states
Takasago International Corporation
19-22, Takanawa 3-chome Minato-ku
Tokyo / JP
Inventor(s)01 / Saito, Takao c/o Takasago Intern. Corp. Fine Chem.
Laboratory 4-11, Nishiyawata 1-chome
Hiratsuka-shi Kanagawa / JP
02 / Matsumura, Kazuhiko c/o Takasago Intern. Corp.
Fine Chem. Laboratory 4-11, Nishiyawata 1-chome
Hiratsuka-shi Kanagawa / JP
03 / Kato, Yasushi c/o Takasago Intern. Corp.
Fine Chem. Laboratory 4-11, Nishiyawata 1-chome
Hiratsuka-shi Kanagawa / JP
04 / Sayo, Noboru c/o Takasago Intern. Corporation
Fine Chem. Laboratory 4-11, Nishiyawata 1-chome
Hiratsuka-shi Kanagawa / JP
05 / Kumobayashi, Hidenori c/o Takasago Intern. Corp.
Fine Chem. Laboratory 4-11, Nishiyawata 1-chome
Hiratsuka-shi Kanagawa / JP
[1995/48]
Representative(s)Dixon, Donald Cossar, et al
Wilson Gunn Gee
Chancery House
Chancery Lane
London WC2A 1QU / GB
[N/P]
Former [1996/13]Dixon, Donald Cossar, et al
Gee & Co. Chancery House Chancery Lane
London WC2A 1QU / GB
Former [1995/48]Moore, Anthony John, et al
Gee & Co. Chancery House Chancery Lane
London WC2A 1QU / GB
Application number, filing date95111576.511.03.1994
[1995/48]
Priority number, dateJP1993007748412.03.1993         Original published format: JP 7748493
[1995/48]
Filing languageEN
Procedural languageEN
PublicationType: A1 Application with search report 
No.:EP0684230
Date:29.11.1995
Language:EN
[1995/48]
Type: B1 Patent specification 
No.:EP0684230
Date:03.07.2002
Language:EN
[2002/27]
Search report(s)(Supplementary) European search report - dispatched on:EP02.10.1995
ClassificationIPC:C07D205/08, C07F7/18, C07D487/04
[1995/48]
CPC:
C07F15/008 (EP); C07C45/50 (EP); C07C45/505 (EP);
C07C67/293 (EP); C07D205/08 (EP); C07D205/085 (EP);
C07F9/5022 (EP); C07F9/65683 (EP); C07F9/65744 (EP);
Y02P20/55 (EP) (-)
C-Set:
C07C45/505, C07C47/228 (EP);
C07C45/50, C07C47/453 (EP);
C07C67/293, C07C69/14 (EP)
Designated contracting statesCH,   DE,   FR,   GB,   IT,   LI,   NL [1995/48]
TitleGerman:4-(R)-1'-Formylethyl Azetidin-2-on-Derivate[1995/48]
English:4-£(R)-1'-formylethyl azetidin-2-one derivatives[1995/48]
French:Dérivés de 4-(R)-1'-formyléthyl-azetidin-2-one[1995/48]
Examination procedure25.04.1996Examination requested  [1996/26]
17.08.1998Despatch of a communication from the examining division (Time limit: M06)
22.02.1999Reply to a communication from the examining division
10.08.1999Despatch of a communication from the examining division (Time limit: M06)
11.02.2000Reply to a communication from the examining division
05.06.2000Despatch of a communication from the examining division (Time limit: M06)
07.12.2000Reply to a communication from the examining division
20.08.2001Despatch of communication of intention to grant (Approval: Yes)
15.01.2002Communication of intention to grant the patent
23.03.2002Fee for grant paid
23.03.2002Fee for publishing/printing paid
Parent application(s)   TooltipEP94301775.6  / EP0614903
Opposition(s)04.04.2003No opposition filed within time limit [2003/26]
Fees paidRenewal fee
25.03.1996Renewal fee patent year 03
26.03.1997Renewal fee patent year 04
30.03.1998Renewal fee patent year 05
29.03.1999Renewal fee patent year 06
29.03.2000Renewal fee patent year 07
05.03.2001Renewal fee patent year 08
22.03.2002Renewal fee patent year 09
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Documents cited:Search[Y]EP0010317  (MERCK & CO INC [US]) [Y] 1,2*pages 44, 45 and 49 *;
 [Y]EP0089139  (BEECHAM GROUP PLC [GB]) [Y] 1,2 *pages 32, 49 and 59*;
 [X]EP0113101  (MERCK & CO INC [US]) [X] 1,2 *Page 12, formula 11; page 16, line 24-line 31; page 54-page 56 and page 59*
ExaminationEP0180189
 EP0188816
 WO8801619
    - SASAKI ET AL, "Synthetic Studies of Carbapenem and Penem Antibiotics. III. A Synthesis of a Key Intermediate for 1-beta-Methylcarbapenem", CHEM. PHARM. BULL., (1992), vol. 40, no. 5, pages 1098 - 1104
    - SHIRAI ET AL, "A New Synthetic Route to the Key Precursor of 1-beta-Methylcarbapenem Antibiotics from (S)-Methyl 3-Hydroxy-2-methylpropanoate", CHEMISTRY LETTERS, (1989), pages 445 - 448
    - SHIRAI ET AL, "A novel, double asymmetric aldol approach to the synthesis of a 1-beta-methyl carbapenem antibiotic precursor", TETRAHEDRON LETTERS, (1988), vol. 29, no. 49, pages 6461 - 6464
    - KAWABATA ET AL, "A novel and efficient synthesis of the key intermediate of 1-beta-methylcarbapenem antibiotics employing [2+2]-cycloaddition reaction of diketene with a chiral imine", TETRAHEDRON, (1988), vol. 44, no. 8, doi:doi:10.1016/S0040-4020(01)81722-1, pages 2149 - 2165, XP003013245

DOI:   http://dx.doi.org/10.1016/S0040-4020(01)81722-1
    - KAWABATA ET AL, "A novel and efficient synthesis of the key intermediate of 1-beta-methylcarbapenem antibiotics from (S)-methyl 3-hydroxy-2-methylpropionate", TETRAHEDRON LETTERS, (1986), vol. 27, no. 51, pages 6241 - 6244
    - SHIH ET AL, "Synthetic carbapenem antibiotics. III. 1-Methyl thienamycin", TETRAHEDRON LETTERS, (1985), vol. 26, no. 5, pages 587 - 590
    - BERKS, ANDREW H, "TETRAHEDRON REPORT NUMBER 387. Preparations of Two Pivotal Intermediates for the Synthesis of 1-beta-Methyl Carbapenem Antibiotics", TETRAHEDRON, (1996), vol. 52, no. 2, pages 331 - 375
The EPO accepts no responsibility for the accuracy of data originating from other authorities; in particular, it does not guarantee that it is complete, up to date or fit for specific purposes.