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Extract from the Register of European Patents

EP About this file: EP0714908

EP0714908 - New 17-(3-imino-2-alkyl-propenyl)-5beta,14beta-androstane derivatives active on the cardiovascular system, processes for their preparation and pharmaceutical compositions containing same [Right-click to bookmark this link]
StatusNo opposition filed within time limit
Status updated on  08.01.1999
Database last updated on 28.06.2024
Most recent event   Tooltip08.01.1999No opposition filed within time limitpublished on 24.02.1999 [1999/08]
Applicant(s)For all designated states
SIGMA-TAU Industrie Farmaceutiche Riunite S.p.A.
Viale Shakespeare, 47
00144 Roma / IT
[N/P]
Former [1998/09]For all designated states
Sigma-Tau Industrie Farmaceutiche Riunite S.p.A.
Viale Shakespeare, 47
00144 Roma / IT
Former [1996/23]For all designated states
Sigma-Tau Industrie Farmaceutiche Riunite S.p.A.
Viale Shakespeare, 47
I-00144 Roma / IT
Inventor(s)01 / Cerri, Alberto
7, Via Monte San Michele
I-20060 Gessate (Milan) / IT
02 / Bianchi, Giuseppe
4, Piazza Adigrat
I-20133 Milan / IT
03 / Ferrari, Patrizia
5, Via Gasparotto
I-21100 Varese / IT
04 / Melloni, Piero
1, Via Centurelli
I-20091 Bresso (Milan) / IT
05 / Quadri, Maria L.
11, Via C. Porta
I-20063 Cernusco S/N (Milan) / IT
[1996/23]
Representative(s)Fassi, Aldo, et al
Hoffmann-Eitle & Partner, Patent-und Rechtsanwälte, Arabellastrasse 4
81925 München / DE
[N/P]
Former [1996/23]Fassi, Aldo, et al
Hoffmann-Eitle & Partner, Patent-und Rechtsanwälte, Arabellastrasse 4
D-81925 München / DE
Application number, filing date95117347.503.11.1995
[1996/23]
Priority number, dateDE1994444248629.11.1994         Original published format: DE 4442486
[1996/23]
Filing languageEN
Procedural languageEN
PublicationType: A2 Application without search report 
No.:EP0714908
Date:05.06.1996
Language:EN
[1996/23]
Type: A3 Search report 
No.:EP0714908
Date:19.06.1996
[1996/25]
Type: B1 Patent specification 
No.:EP0714908
Date:25.02.1998
Language:EN
[1998/09]
Search report(s)(Supplementary) European search report - dispatched on:EP07.05.1996
ClassificationIPC:C07J41/00, A61K31/56, C07J43/00
[1996/25]
CPC:
C07J43/003 (EP,US); A61P9/00 (EP); A61P9/04 (EP);
A61P9/12 (EP); C07J41/0055 (EP,US)
Former IPC [1996/23]C07J41/00, A61K31/56
Designated contracting statesAT,   BE,   CH,   DE,   DK,   ES,   FR,   GB,   GR,   IE,   IT,   LI,   LU,   MC,   NL,   PT,   SE [1996/23]
TitleGerman:Neue 17-(3-Imino-2-alkyl-propenyl)-5beta-14beta-Androstanderivate, zur Behandlung von kardiovaskulären Erkrankungen, ein Verfahren zu ihrer Herstellung und pharmazeutische Präparate davon[1996/23]
English:New 17-(3-imino-2-alkyl-propenyl)-5beta,14beta-androstane derivatives active on the cardiovascular system, processes for their preparation and pharmaceutical compositions containing same[1996/23]
French:Nouveaux dérivés 17-(3-imino-2-alkyl-propényle)-5beta,14beta-androstanes actifs sur le système cardiovasculaire, un procédé pour leur préparation et compositions pharmaceutiques les contenant[1996/23]
Examination procedure18.07.1996Examination requested  [1996/37]
28.02.1997Despatch of communication of intention to grant (Approval: No)
03.07.1997Despatch of communication of intention to grant (Approval: later approval)
08.07.1997Communication of intention to grant the patent
08.10.1997Fee for grant paid
08.10.1997Fee for publishing/printing paid
Opposition(s)26.11.1998No opposition filed within time limit [1999/08]
Fees paidRenewal fee
28.11.1997Renewal fee patent year 03
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Documents cited:Search[PA]EP0659761  (SIGMA TAU IND FARMACEUTI [IT]) [PA] 1-5 * whole document, in particular examples 1 and 13 *;
 [E]EP0688786  (SIGMA TAU IND FARMACEUTI [IT]) [E] 1-4* example 22 *;
 [A]  - D. S. FULLERTON ET AL, "Cardenolide Analogues. I. A 17.beta.-Unsaturated Aldehyde", JOURNAL OF MEDICINAL CHEMISTRY, WASHINGTON US, (1976), vol. 19, no. 11, pages 1330 - 1333, XP002001296 [A] 1-5 * page 1331; table 1 * * page 1332; example 7 *

DOI:   http://dx.doi.org/10.1021/jm00233a015
 [A]  - R. HINTSCHE ET AL, "Biological potency and solution conformation of cardenolides determined by a new 1H NMR method", EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY CHIMICA THERAPEUTICA., PARIS FR, (1985), vol. 20, no. 1, pages 9 - 15, XP002001297 [A] 1-5 * page 10; examples 5,7 * * page 14; table IV *
 [A]  - J. BOUTAGY ET AL, "Cardenolide Analogues. IV. Inhibition of Na+,K+-ATPase", AUSTRALIAN JOURNAL OF PHARMACEUTICAL SCIENCES, (1973), vol. NS2, no. 2, pages 41 - 46, XP002001298 [A] 1-5 * page 43; table I * * page 45, column 1, paragraph 3 *
The EPO accepts no responsibility for the accuracy of data originating from other authorities; in particular, it does not guarantee that it is complete, up to date or fit for specific purposes.