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Extract from the Register of European Patents

EP About this file: EP0737248

EP0737248 - CONTROL OF THE EXPRESSION OF THE IGF-I GENE [Right-click to bookmark this link]
Former [1996/42]GENE EXPRESSION CONTROL
[2007/22]
StatusNo opposition filed within time limit
Status updated on  19.09.2008
Database last updated on 25.09.2024
Most recent event   Tooltip19.09.2008No opposition filed within time limitpublished on 22.10.2008  [2008/43]
Applicant(s)For all designated states
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE -CNRS-
3, rue Michel-Ange
75016 Paris / FR
For all designated states
INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM)
101, rue de Tolbiac
75654 Paris Cédex 13 / FR
For all designated states
MUSEUM NATIONAL D'HISTOIRE NATURELLE
57, rue Cuvier
75005 Paris / FR
[N/P]
Former [2007/46]For all designated states
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS)
3, rue Michel Ange
75016 Paris / FR
For all designated states
INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM)
101, rue de Tolbiac
75654 Paris Cédex 13 / FR
For all designated states
MUSEUM NATIONAL D'HISTOIRE NATURELLE
57, rue Cuvier
75005 Paris / FR
Former [1996/42]For all designated states
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS)
3, rue Michel Ange
75016 Paris / FR
For all designated states
INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM)
101, rue de Tolbiac
75654 Paris Cédex 13 / FR
For all designated states
MUSEUM NATIONAL D'HISTOIRE NATURELLE
57, rue Cuvier
F-75005 Paris / FR
Inventor(s)01 / GIOVANNANGELI, Carine
16, rue Larrey
F-75005 Paris / FR
02 / HELENE, Claude
14, quai d'Orléans
F-75004 Paris / FR
[1996/42]
Representative(s)Dernoncour, Roxane, et al
Aventis Pharma S.A.
Direction des Brevets
Tri LEO/144
20, avenue Raymond Aron
92165 Antony Cedex / FR
[N/P]
Former [2007/52]Dernoncour, Roxane, et al
Aventis Pharma S.A. Direction des Brevets, Tri LEO/144 20, avenue Raymond Aron
92165 Antony Cedex / FR
Former [1996/42]Savina, Jacques, et al
RHONE-POULENC RORER S.A., Direction des Brevets, 20 avenue Raymond Aron
92160 Antony Cédex / FR
Application number, filing date95905172.327.12.1994
[1996/42]
WO1994FR01536
Priority number, dateFR1993001579829.12.1993         Original published format: FR 9315798
[1996/42]
Filing languageFR
Procedural languageFR
PublicationType: A1 Application with search report
No.:WO9518223
Date:06.07.1995
Language:FR
[1995/29]
Type: A1 Application with search report 
No.:EP0737248
Date:16.10.1996
Language:FR
The application published by WIPO in one of the EPO official languages on 06.07.1995 takes the place of the publication of the European patent application.
[1996/42]
Type: B1 Patent specification 
No.:EP0737248
Date:14.11.2007
Language:FR
[2007/46]
Search report(s)International search report - published on:EP06.07.1995
ClassificationIPC:C12N15/11, C12N15/86, C07H21/02, A61K31/70
[1996/42]
CPC:
C12N15/113 (EP,US); A61P31/12 (EP); A61P31/22 (EP);
A61P35/00 (EP); C12N15/1132 (EP,US); C12N15/1136 (EP,US);
A61K38/00 (EP,US); C12N2310/152 (EP,US); C12N2310/53 (EP,US);
C12N2310/531 (EP,US); C12N2310/532 (EP,US); Y10S977/802 (EP,US);
Y10S977/916 (EP,US); Y10S977/92 (EP,US) (-)
Designated contracting statesAT,   BE,   CH,   DE,   DK,   ES,   FR,   GB,   GR,   IE,   IT,   LI,   LU,   NL,   PT,   SE [1996/42]
TitleGerman:KONTROLLE DER EXPRIMIERUNG DES IGF-I GENS[2007/22]
English:CONTROL OF THE EXPRESSION OF THE IGF-I GENE[2007/22]
French:CONTROLE DE L'EXPRESSION DU GENE DE L'IGF-I[2007/22]
Former [1996/42]KONTROLLE DER GEN- EXPRIMIERUNG
Former [1996/42]GENE EXPRESSION CONTROL
Former [1996/42]CONTROLE DE L'EXPRESSION DE GENES
Entry into regional phase20.06.1996National basic fee paid 
20.06.1996Designation fee(s) paid 
20.06.1996Examination fee paid 
Examination procedure29.06.1995Request for preliminary examination filed
International Preliminary Examining Authority: EP
20.06.1996Examination requested  [1996/43]
04.05.2004Despatch of a communication from the examining division (Time limit: M06)
15.11.2004Reply to a communication from the examining division
04.02.2005Despatch of a communication from the examining division (Time limit: M04)
21.07.2005Despatch of communication that the application is deemed to be withdrawn, reason: reply to the communication from the examining division not received in time
30.09.2005Reply to a communication from the examining division
18.01.2006Despatch of a communication from the examining division (Time limit: M06)
28.07.2006Reply to a communication from the examining division
24.04.2007Date of oral proceedings
11.05.2007Communication of intention to grant the patent
11.05.2007Minutes of oral proceedings despatched
21.09.2007Fee for grant paid
21.09.2007Fee for publishing/printing paid
Divisional application(s)EP07007057.8  / EP1939290
Opposition(s)15.08.2008No opposition filed within time limit [2008/43]
Request for further processing for:30.09.2005Request for further processing filed
30.09.2005Full payment received (date of receipt of payment)
Request granted
14.10.2005Decision despatched
Fees paidRenewal fee
22.11.1996Renewal fee patent year 03
21.11.1997Renewal fee patent year 04
23.11.1998Renewal fee patent year 05
20.11.1999Renewal fee patent year 06
23.11.2000Renewal fee patent year 07
20.12.2001Renewal fee patent year 08
15.02.2003Renewal fee patent year 09
01.03.2004Renewal fee patent year 10
03.01.2005Renewal fee patent year 11
02.01.2006Renewal fee patent year 12
13.12.2006Renewal fee patent year 13
Penalty fee
Additional fee for renewal fee
31.12.200209   M06   Fee paid on   15.02.2003
31.12.200310   M06   Fee paid on   01.03.2004
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Cited inInternational search[Y]WO9106626  (GILEAD SCIENCES INC [US]) [Y] 1,2,6,24 * page 4, line 31 - page 5, line 35 * * example 8 * * claim - *;
 [Y]WO9219732  (GENSET SA [FR]) [Y] 1,2,5,20,23 * page 17, line 11 - page 18, line 4 * * page 24, line 35 - page 25, line 33 * * page 33 * * figures 1,5 * * claim - *;
 [A]WO9312230  (STANFORD RES INST INT [US]) [A] 1 * page 8, line 25 - line 31 * * page 28, line 34 - page 33, line 32 ** figures 12B,13; claims 19-23 *;
 [DY]FR2687411  (NICE SOPHIA ANTIPOLIS UNIVERSI [FR]) [DY] 1-12,14-25 * the whole document *
 [Y]  - GIOVANNANGELI, C. ET AL., "Oligonucleotide clamps arrest DNA synthesis on a single - stranded DNA target.", PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 90 (21). 1993. 10013-10017 [Y] 1-4,7-12,14-19,21,22,25 * the whole document *
 [DA]  - GIOVANNANGELI, C. ET AL., "SINGLE - STRANDED DNA AS A TARGET FOR TRIPLE - HELIX FORMATION.", J AM CHEM SOC 113 (20). 1991. 7775-7777 [DA] 1-4,21,22 * the whole document *
 [T]  - HELENE, C., "Rational design of sequence-specific DNA ligands for artificial control of gene expression", PURE & APPLIED CHEMISTRY, vol. 66, no. 4, pages 663 - 669 [T] 1-4 * page 667, paragraph 3 * * figure 4 *
 [T]  - KANDIMALLA, E. & AGRAWAL, S., "Single-stranded-targeted triplex formation: stability, specificity and RNase H activation properties", GENE, AMSTERDAM NL, (19941104), vol. 149, pages 115 - 121 [T] 1-4 * figure 1 *
Examination   - ROBERTS R.; CROTHERS D., "Stability and properties of double and triple helices: dramatic effects of RNA or DNA backbone composition", SCIENCE, (19921127), vol. 258, pages 1463 - 1466, XP002026847

DOI:   http://dx.doi.org/10.1126/science.1279808
    - MILLIGAN J. ET AL, "Oligoribonucleotide synthesis using T7 RNA polymerase and synthetic DNA duplexes", NUCLEIC ACIDS RESEARCH, (1987), vol. 15, pages 8783 - 8798, XP002360370
    - LANDRETH K. ET AL, "Insulin-like growth factor-I regulates pro-B cell differentiation", BLOOD, (19920901), vol. 80, pages 1207 - 1212
    - MOATS-STAATS B. ET AL, "Insulin-like growth factor-I (IGF-I) antisense oligodeoxynucleotide mediated inhibition of DNA synthesis by WI-38 cells: evidence for autocrine actions of IGF-I", MOLECULAR ENDOCRINOLOGY, (1993), vol. 7, pages 171 - 180
The EPO accepts no responsibility for the accuracy of data originating from other authorities; in particular, it does not guarantee that it is complete, up to date or fit for specific purposes.