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Extract from the Register of European Patents

EP About this file: EP0750512

EP0750512 - A MEDICAL USE OF MATRIX METALLOPROTEINASE INHIBITORS FOR INHIBITING TISSUE CONTRACTION [Right-click to bookmark this link]
StatusNo opposition filed within time limit
Status updated on  19.05.2006
Database last updated on 22.08.2024
Most recent event   Tooltip14.12.2007Change - applicantpublished on 16.01.2008  [2008/03]
Applicant(s)For all designated states
INSTITUTE OF OPHTHALMOLOGY
11-43 Bath Street
London EC1V 9EL / GB
For all designated states
MOORFIELDS EYE HOSPITAL NHS FOUNDATION TRUST
162 City Road
London EC1V 2PD / GB
[2008/03]
Former [1997/01]For all designated states
INSTITUTE OF OPHTHALMOLOGY
11-43 Bath Street
London EC1V 9EL / GB
For all designated states
UNIVERSITY OF FLORIDA
223 Grinter Hall
Gainesville, Florida 32611-2037 / US
Inventor(s)01 / KHAW, Peng Tee, Institute of Ophthalmology
University of London 11-43 Bath Street
London EC1V 9EL / GB
02 / SCHULTZ, Gregory Scott, University of Florida
223 Grinter Hall
Gainesville, FL 32611-2037 / US
[1997/01]
Representative(s)Silveston, Judith, et al
ABEL & IMRAY
20 Red Lion Street
London, WC1R 4PQ / GB
[N/P]
Former [1997/01]Silveston, Judith, et al
ABEL & IMRAY Northumberland House 303-306 High Holborn
London, WC1V 7LH / GB
Application number, filing date95911409.116.03.1995
[1997/01]
WO1995GB00576
Priority number, dateGB1994000507616.03.1994         Original published format: GB 9405076
[1997/01]
Filing languageEN
Procedural languageEN
PublicationType: A1 Application with search report
No.:WO9524921
Date:21.09.1995
Language:EN
[1995/40]
Type: A1 Application with search report 
No.:EP0750512
Date:02.01.1997
Language:EN
The application published by WIPO in one of the EPO official languages on 21.09.1995 takes the place of the publication of the European patent application.
[1997/01]
Type: B1 Patent specification 
No.:EP0750512
Date:13.07.2005
Language:EN
[2005/28]
Search report(s)International search report - published on:EP21.09.1995
ClassificationIPC:A61K38/55, A61K31/405, C07K16/40, A61P17/00
[2004/47]
CPC:
C07K16/40 (EP,US); A61K31/4045 (EP,US); A61K31/405 (EP,US);
A61K38/55 (EP,US); A61K45/06 (EP,US); A61K8/44 (EP,US);
A61K8/492 (EP,US); A61K8/64 (EP,US); A61P17/00 (EP);
A61Q19/08 (EP,US); A61K2800/782 (EP,US) (-)
Former IPC [1997/01]A61K38/55, A61K31/405, C07K16/40
Designated contracting statesCH,   DE,   FR,   GB,   IT,   LI,   NL [2000/11]
Former [1997/01]CH,  DE,  FR,  GB,  IT,  NL 
TitleGerman:MEDIZINISCHE VERWENDUNG VON MATRIXMETALLPROTEINE-INHIBITOREN ZUR HEMMUNG VON GEWEBEKONTRAKTION[1997/01]
English:A MEDICAL USE OF MATRIX METALLOPROTEINASE INHIBITORS FOR INHIBITING TISSUE CONTRACTION[1997/01]
French:UTILISATION A DES FINS MEDICALES D'INHIBITEURS DE METALLOPROTEASES MATRICIELLES DANS LE TRAITEMENT DE LA CONTRACTION TISSULAIRE[1997/01]
Entry into regional phase14.10.1996National basic fee paid 
14.10.1996Designation fee(s) paid 
14.10.1996Examination fee paid 
Examination procedure02.10.1995Request for preliminary examination filed
International Preliminary Examining Authority: EP
14.10.1996Examination requested  [1997/01]
16.01.2001Despatch of a communication from the examining division (Time limit: M06)
24.07.2001Reply to a communication from the examining division
27.12.2001Despatch of a communication from the examining division (Time limit: M08)
11.10.2002Despatch of communication that the application is deemed to be withdrawn, reason: reply to the communication from the examining division not received in time
19.12.2002Reply to a communication from the examining division
28.07.2003Despatch of a communication from the examining division (Time limit: M06)
22.01.2004Reply to a communication from the examining division
09.11.2004Communication of intention to grant the patent
03.03.2005Fee for grant paid
03.03.2005Fee for publishing/printing paid
Opposition(s)18.04.2006No opposition filed within time limit [2006/25]
Request for further processing for:19.12.2002Request for further processing filed
11.12.2002Full payment received (date of receipt of payment)
Request granted
08.01.2003Decision despatched
Fees paidRenewal fee
12.03.1997Renewal fee patent year 03
10.08.1998Renewal fee patent year 04
11.03.1999Renewal fee patent year 05
13.03.2000Renewal fee patent year 06
16.03.2001Renewal fee patent year 07
13.03.2002Renewal fee patent year 08
11.03.2003Renewal fee patent year 09
15.03.2004Renewal fee patent year 10
12.05.2005Renewal fee patent year 11
Penalty fee
Additional fee for renewal fee
31.03.199804   M06   Fee paid on   10.08.1998
31.03.200511   M06   Fee paid on   12.05.2005
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Cited inInternational search[DXY]US5189178  (GALARDY RICHARD E [US], et al) [DX] 4,5,10-14 * column W * [Y] 1-25;
 [XY]WO9321942  (BRITISH BIO TECHNOLOGY [GB], et al) [X] 4,5,10,11,13,14 * the whole document * [Y] 1-25
 [DY]  - Schultz GS et al, "Treatment of alkali-injured rabbit corneas with a synthetic inhibitor of matrix metalloproteinases.", INVEST OPHTHALMOL VIS SCI (UNITED STATES), NOV 1992, VOL. 33, NO. 12, PAGE(S) 3325-31, [DY] 1-25 * the whole document *
 [Y]  - E. RATZENHOFER ET AL., "In-vitro inhibition of collagenase activity in epidermolysis bullosa hereditaria dystrophica", Z HAUTKR (GERMANY, WEST), DEC 15 1978, VOL. 53, NO. 24, PAGE(S) 929-34, [Y] 1-25 * the whole document *
 [Y]  - KRIEG T ET AL, "Hereditare bullose Epidermolysen. Neuere Aspekte zur Diagnostik und Therapie.", HAUTARZT (GERMANY, WEST), APR 1986, VOL. 37, NO. 4, PAGE(S) 185-9, [Y] 1-25 * the whole document *
 [Y]  - E.E. PEACOCK, "Healing and control of healing - Introduction", WORLD J. SURG., VOL. 4, NO. 3, (1980), pages 269 - 270 [Y] 19,22-24 * the whole document *
 [A]  - HEMBRY RM ET AL, "Immunolocalization of collagenase and tissue inhibitor of metalloproteinases (TIMP) in hypertrophic scar tissue.", BR J DERMATOL (ENGLAND), OCT 1986, VOL. 115, NO. 4, PAGE(S) 409-20, [A] 1-25 * the whole document *
 [A]  - EISEN A.Z. ET AL, "Behavior of epidermolysis bullosa fibroblasts in a hydrated collagen lattice", J. INVEST. DERMATOL. (USA), 1987, VOL. 88, NO. 6, PAGE(S) 741-746, [A] 1-25 * the whole document *
The EPO accepts no responsibility for the accuracy of data originating from other authorities; in particular, it does not guarantee that it is complete, up to date or fit for specific purposes.