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Extract from the Register of European Patents

EP About this file: EP0760666

EP0760666 - USE OF OLIGONUCLEOTIDE PHOSPHOROTHIOATE FOR DEPLETING COMPLEMENT AND FOR REDUCING BLOOD PRESSURE [Right-click to bookmark this link]
StatusThe application has been withdrawn
Status updated on  06.02.1998
Database last updated on 12.10.2024
Most recent event   Tooltip06.02.1998Withdrawal of applicationpublished on 25.03.1998 [1998/13]
Applicant(s)For all designated states
HYBRIDON, Inc.
One Innovation Drive Massachusetts Biotechnology Research Park Worcester
Massachusetts 01605 / US
[N/P]
Former [1997/11]For all designated states
HYBRIDON, Inc.
One Innovation Drive Massachusetts Biotechnology Research Park
Worcester, Massachusetts 01605 / US
Inventor(s)01 / GALBRAITH, Wayne, M.
918 Cornell Street
Fredericksburg, VA 22401 / US
02 / AGRAWAL, Sudhir
61 Lamplighter Drive
Shrewsbury, MA 01545 / US
[1997/11]
Representative(s)Vossius, Volker, et al
ZSP Patentanwälte PartG mbB
Radlkoferstrasse 2
81373 München / DE
[N/P]
Former [1997/11]Vossius, Volker, Dr., et al
Dr. Volker Vossius, Patentanwaltskanzlei - Rechtsanwaltskanzlei, Holbeinstrasse 5
81679 München / DE
Application number, filing date95920471.019.05.1995
[1997/11]
WO1995US06161
Priority number, dateUS1994025085327.05.1994         Original published format: US 250853
[1997/11]
Filing languageEN
Procedural languageEN
PublicationType: A1 Application with search report
No.:WO9532719
Date:07.12.1995
Language:EN
[1995/52]
Type: A1 Application with search report 
No.:EP0760666
Date:12.03.1997
Language:EN
The application published by WIPO in one of the EPO official languages on 07.12.1995 takes the place of the publication of the European patent application.
[1997/11]
Search report(s)International search report - published on:EP07.12.1995
ClassificationIPC:A61K31/70
[1997/11]
CPC:
A61K31/70 (EP); A61P37/06 (EP); A61P9/12 (EP)
Designated contracting statesAT,   BE,   CH,   DE,   DK,   ES,   FR,   GB,   GR,   IE,   IT,   LI,   LU,   MC,   NL,   PT,   SE [1997/11]
TitleGerman:VERWENDUNG EINES OLIGONUKLEOTID-PHOSPHOROTIOATES ZUR KOMPLEMENTDEPLETION UND ZUR SENKUNG DES BLUTDRUCKS[1997/11]
English:USE OF OLIGONUCLEOTIDE PHOSPHOROTHIOATE FOR DEPLETING COMPLEMENT AND FOR REDUCING BLOOD PRESSURE[1997/11]
French:UTILISATION DE PHOSPHOROTHIOATE OLIGONUCLEOTIDIQUE POUR LA DEPLETION DU COMPLEMENT ET LA REDUCTION DE LA PRESSION SANGUINE[1997/11]
Entry into regional phase26.11.1996National basic fee paid 
26.11.1996Designation fee(s) paid 
26.11.1996Examination fee paid 
Examination proceduredeletedDecision about request for accelerated examination - accepted: No
05.12.1995Request for preliminary examination filed
International Preliminary Examining Authority: EP
26.11.1996Examination requested  [1997/11]
26.11.1996Request for accelerated examination filed
20.01.1998Application withdrawn by applicant  [1998/13]
Fees paidRenewal fee
07.05.1997Renewal fee patent year 03
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Cited inInternational search[X]  - "Antisense inhibition of AT1 receptor mRNA and angiotensinogen mRNA in the brain of spontaneously hypertensive rats reduces hypertension of neurogenic origin", REGUL.PEPT., vol. 49, pages 167 - 74 [X] 1-13 * see page 167, summary * * page 170, column R, line 3 - page 171, column R, line 2 * * page 172, column L, line 16 - line 18 *
 [XP]  - "Antisense inhibition of hypertension in the spontaneously hypertensive rat", HYPERTENSION, vol. 25, no. 3, pages 314 - 9 [XP] 1-13 * see page 314, summary * * page 315, column L, paragraph 1 * * page 318, column L, line 35 - line 38 *
 [XP]  - "Complement activation and hemostatic changes following intravenous administration of phosphorothioate oligonucleotides in the mokey", ANTISENSE RES.DEV.(FALL 1994), vol. 4, no. 3, pages 201 - 6 [XP] 27-39 * page 206, column L, line 15 - line 32 *
 [Y]  - "Antisense Nonmuscle Myosin Heavy Chain and c-myb Oligonucleotides Suppress Smooth Muscle Cell Proliferation In Vitro", CIRC.RES., vol. 70, no. 4, pages 835 - 43 [Y] 1-39 * page 835, column L, line 15 - line 20 * * see page 843, reference no. 9; page 836, column L, paragraph 3 - column R, paragraph 1 * * page 837, column R, line 14 - line 18 * * page 842, column L, line 28 - line 40 *
 [Y]  - "Antisense Oligonucleotides decrease expression of human CD46, a regulator of complement", TRANSPL.PROC., vol. 25, no. 5, pages 2922 - 23 [Y] 1-39 * page 2922 *
The EPO accepts no responsibility for the accuracy of data originating from other authorities; in particular, it does not guarantee that it is complete, up to date or fit for specific purposes.