EP0760864 - DNA ENCODING GLUTAMATE GATED CHLORIDE CHANNELS [Right-click to bookmark this link] | Status | No opposition filed within time limit Status updated on 30.09.2005 Database last updated on 24.08.2024 | Most recent event Tooltip | 04.01.2008 | Lapse of the patent in a contracting state New state(s): PT | published on 06.02.2008 [2008/06] | Applicant(s) | For all designated states Merck & Co., Inc. 126 East Lincoln Avenue Rahway, New Jersey 07065 / US | For all designated states The Trustees of Columbia University in the City of New York Broadway and West 116th Street New York, NY 10027-6699 / US | [N/P] |
Former [2004/19] | For all designated states MERCK & CO., INC. 126 East Lincoln Avenue Rahway, New Jersey 07065 / US | ||
For all designated states The Trustees of Columbia University in the City of New York Broadway and West 116th Street New York, NY 10027-6699 / US | |||
Former [1997/47] | For all designated states Merck & Co., Inc. (a New Jersey corp.) 126 East Lincoln Avenue Rahway, N.J. 07065 / US | ||
For all designated states The Trustees of Columbia University in the City of New York Broadway and West 116th Street New York, NY 10027-6699 / US | |||
Former [1997/11] | For all designated states Merck & Co., Inc. (a New Jersey corp.) 126 East Lincoln Avenue Rahway, N.J. 07065 / US | Inventor(s) | 01 /
CULLY, Doris F. 126 East Lincoln Avenue Rahway, NJ 07065 / US | 02 /
ARENA, Joseph P. 126 East Lincoln Avenue Rahway, NJ 07065 / US | 03 /
LIU, Ken K. 126 East Lincoln Avenue Rahway, NJ 07065 / US | 04 /
VASSILATIS, Demetrios 126 East Lincoln Avenue Rahway, NJ 07065 / US | [1997/11] | Representative(s) | Horgan, James Michael Frederic, et al Merck & Co., Inc. European Patent Department Terlings Park Eastwick Road, Harlow Essex CM20 2QR / GB | [N/P] |
Former [2004/27] | Horgan, James Michael Frederic, et al Merck & Co., Inc. European Patent Department Terlings Park Eastwick Road Harlow, Essex CM20 2QR / GB | ||
Former [2004/19] | Thompson, John Dr., et al Merck & Co., Inc. European Patent Department Terlings Park Eastwick Road Harlow, Essex CM20 2QR / GB | ||
Former [1997/11] | Thompson, John Dr. Merck & Co., Inc. European Patent Department Terlings Park Eastwick Road Harlow, Essex CM20 2QR / GB | Application number, filing date | 95920633.5 | 19.05.1995 | [1997/11] | WO1995US06556 | Priority number, date | US19940249112 | 25.05.1994 Original published format: US 249112 | [1997/11] | Filing language | EN | Procedural language | EN | Publication | Type: | A1 Application with search report | No.: | WO9532302 | Date: | 30.11.1995 | Language: | EN | [1995/51] | Type: | A1 Application with search report | No.: | EP0760864 | Date: | 12.03.1997 | Language: | EN | The application published by WIPO in one of the EPO official languages on 30.11.1995 takes the place of the publication of the European patent application. | [1997/11] | Type: | B1 Patent specification | No.: | EP0760864 | Date: | 24.11.2004 | Language: | EN | [2004/48] | Search report(s) | International search report - published on: | US | 30.11.1995 | (Supplementary) European search report - dispatched on: | EP | 21.12.1999 | Classification | IPC: | C12P21/06, C12N15/00, C12N1/00, A01N61/00, C07K1/00, C07K16/00, C07H21/02, A61K39/395, A61K39/00, A61K39/002, G01N33/53 | [1997/11] | CPC: |
C07K14/70571 (EP,US);
A61P31/00 (EP);
A61P43/00 (EP);
A61K38/00 (EP,US);
C12N2799/026 (EP,US)
| Designated contracting states | AT, BE, CH, DE, DK, ES, FR, GB, GR, IE, IT, LI, LU, NL, PT, SE [1997/11] | Title | German: | FÜR DIE GLUTAMATABHÄNGIGEN CHLORIDKANÄLE KODIERENDE DNA | [1997/11] | English: | DNA ENCODING GLUTAMATE GATED CHLORIDE CHANNELS | [1997/11] | French: | ADN CODANT LES CANAUX A CHLORURE DEBLOQUES PAR GLUTAMATE | [1997/11] | Entry into regional phase | 27.12.1996 | National basic fee paid | 27.12.1996 | Search fee paid | 27.12.1996 | Designation fee(s) paid | 27.12.1996 | Examination fee paid | Examination procedure | 19.12.1995 | Request for preliminary examination filed | 27.12.1996 | Examination requested [1997/11] | 30.01.2002 | Despatch of a communication from the examining division (Time limit: M06) | 05.08.2002 | Reply to a communication from the examining division | 18.11.2002 | Despatch of a communication from the examining division (Time limit: M06) | 14.05.2003 | Reply to a communication from the examining division | 13.01.2004 | Date of oral proceedings | 28.01.2004 | Minutes of oral proceedings despatched | 18.03.2004 | Communication of intention to grant the patent | 28.09.2004 | Fee for grant paid | 28.09.2004 | Fee for publishing/printing paid | Opposition(s) | 25.08.2005 | No opposition filed within time limit [2005/46] | Fees paid | Renewal fee | 02.06.1997 | Renewal fee patent year 03 | 02.06.1998 | Renewal fee patent year 04 | 31.05.1999 | Renewal fee patent year 05 | 31.05.2000 | Renewal fee patent year 06 | 31.05.2001 | Renewal fee patent year 07 | 31.05.2002 | Renewal fee patent year 08 | 07.05.2003 | Renewal fee patent year 09 | 05.05.2004 | Renewal fee patent year 10 |
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Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court. | Lapses during opposition Tooltip | AT | 24.11.2004 | BE | 24.11.2004 | CH | 24.11.2004 | LI | 24.11.2004 | NL | 24.11.2004 | DK | 24.02.2005 | GR | 24.02.2005 | SE | 24.02.2005 | PT | 24.04.2005 | IE | 19.05.2005 | LU | 19.05.2005 | [2008/06] |
Former [2007/26] | AT | 24.11.2004 | |
BE | 24.11.2004 | ||
CH | 24.11.2004 | ||
LI | 24.11.2004 | ||
NL | 24.11.2004 | ||
DK | 24.02.2005 | ||
GR | 24.02.2005 | ||
SE | 24.02.2005 | ||
IE | 19.05.2005 | ||
LU | 19.05.2005 | ||
Former [2007/16] | AT | 24.11.2004 | |
BE | 24.11.2004 | ||
CH | 24.11.2004 | ||
LI | 24.11.2004 | ||
NL | 24.11.2004 | ||
DK | 24.02.2005 | ||
GR | 24.02.2005 | ||
SE | 24.02.2005 | ||
IE | 19.05.2005 | ||
LU | 31.05.2005 | ||
Former [2006/25] | AT | 24.11.2004 | |
BE | 24.11.2004 | ||
CH | 24.11.2004 | ||
LI | 24.11.2004 | ||
NL | 24.11.2004 | ||
DK | 24.02.2005 | ||
GR | 24.02.2005 | ||
IE | 19.05.2005 | ||
Former [2006/14] | AT | 24.11.2004 | |
BE | 24.11.2004 | ||
CH | 24.11.2004 | ||
LI | 24.11.2004 | ||
NL | 24.11.2004 | ||
DK | 24.02.2005 | ||
GR | 24.02.2005 | ||
Former [2005/51] | AT | 24.11.2004 | |
BE | 24.11.2004 | ||
CH | 24.11.2004 | ||
LI | 24.11.2004 | ||
DK | 24.02.2005 | ||
GR | 24.02.2005 | ||
Former [2005/46] | AT | 24.11.2004 | |
CH | 24.11.2004 | ||
LI | 24.11.2004 | ||
DK | 24.02.2005 | ||
GR | 24.02.2005 | ||
Former [2005/36] | AT | 24.11.2004 | |
CH | 24.11.2004 | ||
LI | 24.11.2004 | ||
GR | 24.02.2005 | ||
Former [2005/26] | CH | 24.11.2004 | |
LI | 24.11.2004 | ||
GR | 24.02.2005 | ||
Former [2005/25] | CH | 24.11.2004 | |
LI | 24.11.2004 | Documents cited: | Search | [A]WO9210583 (ZYMOGENETICS INC [US], et al) [A] 1-34 * abstract * * claims 1-38 *; | [A]WO9219717 (BAYLOR COLLEGE MEDICINE [US], et al) [A] 1-34 * abstract * * page 1 - page 13 *; | [E]WO9634940 (MERCK & CO INC [US], et al) [E] 7,9,10,12 * abstract ** claims 1-14 *; | [XDA] - ROHRER S.P., "Photoaffinity labelling of avermectin binding sites from Caernorhabditis elegan and Drosophila melanogaster", PROC. NATL. ACAD. SCI. USA, (199205), vol. 89, pages 4168 - 4172, XP002113577 [XD] 1-11,14-34 * the whole document * [A] 12,13 DOI: http://dx.doi.org/10.1073/pnas.89.9.4168 | [PX] - CULLY D.F. ET AL., "Cloning of an avermectin-sensitive glutamate-gated chloride channel from Caernorhabditis elegans", NATURE, (19941020), vol. 371, pages 707 - 711, XP002113578 [PX] 1-11,14-34 * the whole document * DOI: http://dx.doi.org/10.1038/371707a0 | [A] - CULLY D F ET AL, "SOLUBILIZATION AND CHARACTERIZATION OF A HIGH AFFINITY IVERMECTIN BINDING SITE FROM CAENORHABDITIS ELEGANS", MOLECULAR PHARMACOLOGY,US,BALTIMORE, MD, vol. 40, no. 2, ISSN 0026-895X, page 326-332, XP002052916 [A] 1-34 * the whole document * | [A] - KANNER B.I., "Glutamate transporters from brain", FEBS LETTERS, (199306), vol. 325, no. 1-2, pages 95 - 99, XP002124431 [A] 1-34 * the whole document * DOI: http://dx.doi.org/10.1016/0014-5793(93)81421-U | [A] - MINAKAMI R. ET AL., "Molecular cloning and the functional expression of two isoforms of human metabotropic glutamate receptor subtype 5.", BIOCHEM. BIOPHYS. RES. COMMUN., (19940330), vol. 199, no. 3, pages 1136 - 1143, XP002124432 [A] 1-34 * the whole document * DOI: http://dx.doi.org/10.1006/bbrc.1994.1349 | [A] - MROZIK H ET AL, "DISCOVERY OF NOVEL AVERMECTINS WITH UNPRECEDENTED INSECTICIDAL ACTIVITY", EXPERIENTIA,CH,BIRKHAUSER VERLAG. BASEL, vol. 45, no. 3, ISSN 0014-4754, page 315-316, XP000029339 [A] 15-34 * the whole document * DOI: http://dx.doi.org/10.1007/BF01951823 | International search | [YP]US5385831 (MULVIHILL EILEEN R [US], et al) | [Y] - MOLECULAR PHARMACOLOGY, Volume 40, Number 3, issued June 1991, ARENA et al., "Avermectin-Sensitive Chloride Currents Induced by Caenorhabditis Elegans RNA in Xenopus Oocytes", pages 368-374. | [Y] - MOLECULAR BRAIN RESEARCH, Volume 15, Number 3-4, issued October 1992, ARENA et al., "Expression of a Glutamate-Activated Chloride Current in Xenopus Oocytes Injected with Caenorhabditis Elegans RNA: Evidence for Modulation by Avermectin", pages 339-348. | [Y] - PARASITOLOGY TODAY, Volume 10, Number 1, issued January 1994, ARENA J.P., "Expression of Caenorhabditis Elegans mRNA in Xenopus Oocytes: A Model System to Study the Mechanism of Action of Avermectins", pages 35-37. | [Y] - E. HARLOW et al., "Antibodies: A Laboratory Manual", Published January 1988, by COLD SPRING HARBOR LABORATORY PRESS (N.Y.), pages 92-115. | [Y] - SCIENCE, Volume 241, issued 29 July 1988, JULIUS et al., "Molecular Characterization of a Functional cDNA Encoding the Serotonin 1c Receptor", pages 558-564. | [Y] - JOURNAL OF EXPERIMENTAL BIOLOGY, Volume 142, Number 0, issued January 1989, ZUFALL et al., "The Insecticide Avermectin B1a Activates a Chloride Channel in Crayfish Muscle Membrane", pages 191-205. |