blank Quick help
blank Maintenance news

Scheduled maintenance

Regular maintenance outages:
between 05.00 and 05.15 hrs CET (Monday to Sunday).

Other outages
Availability
Register Forum

2022.02.11

More...
blank News flashes

News Flashes

New version of the European Patent Register – SPC proceedings information in the Unitary Patent Register.

2024-07-24

More...
blank Related links

Release notes
European Patent Register Assistant
European Patent Register Resource Book
European Patent Register – pocket guide
FAQ - European Patent Register
FAQ - Register Alert
Federated Register (Flyer)
Global Dossier (Flyer)
Register events
Deep link coverage
Federated Register content
The Patent Information Tour
Fair use charter

Extract from the Register of European Patents

EP About this file: EP0760864

EP0760864 - DNA ENCODING GLUTAMATE GATED CHLORIDE CHANNELS [Right-click to bookmark this link]
StatusNo opposition filed within time limit
Status updated on  30.09.2005
Database last updated on 24.08.2024
Most recent event   Tooltip04.01.2008Lapse of the patent in a contracting state
New state(s): PT		published on 06.02.2008  [2008/06]
Applicant(s)For all designated states
Merck & Co., Inc.
126 East Lincoln Avenue
Rahway, New Jersey 07065 / US
For all designated states
The Trustees of Columbia University in the City of New York
Broadway and West 116th Street
New York, NY 10027-6699 / US
[N/P]
Former [2004/19]For all designated states
MERCK & CO., INC.
126 East Lincoln Avenue
Rahway, New Jersey 07065 / US
For all designated states
The Trustees of Columbia University in the City of New York
Broadway and West 116th Street
New York, NY 10027-6699 / US
Former [1997/47]For all designated states
Merck & Co., Inc. (a New Jersey corp.)
126 East Lincoln Avenue
Rahway, N.J. 07065 / US
For all designated states
The Trustees of Columbia University in the City of New York
Broadway and West 116th Street
New York, NY 10027-6699 / US
Former [1997/11]For all designated states
Merck & Co., Inc. (a New Jersey corp.)
126 East Lincoln Avenue
Rahway, N.J. 07065 / US
Inventor(s)01 / CULLY, Doris F.
126 East Lincoln Avenue
Rahway, NJ 07065 / US
02 / ARENA, Joseph P.
126 East Lincoln Avenue
Rahway, NJ 07065 / US
03 / LIU, Ken K.
126 East Lincoln Avenue
Rahway, NJ 07065 / US
04 / VASSILATIS, Demetrios
126 East Lincoln Avenue
Rahway, NJ 07065 / US
[1997/11]
Representative(s)Horgan, James Michael Frederic, et al
Merck & Co., Inc.
European Patent Department
Terlings Park
Eastwick Road, Harlow
Essex CM20 2QR / GB
[N/P]
Former [2004/27]Horgan, James Michael Frederic, et al
Merck & Co., Inc. European Patent Department Terlings Park Eastwick Road
Harlow, Essex CM20 2QR / GB
Former [2004/19]Thompson, John Dr., et al
Merck & Co., Inc. European Patent Department Terlings Park Eastwick Road
Harlow, Essex CM20 2QR / GB
Former [1997/11]Thompson, John Dr.
Merck & Co., Inc. European Patent Department Terlings Park Eastwick Road
Harlow, Essex CM20 2QR / GB
Application number, filing date95920633.519.05.1995
[1997/11]
WO1995US06556
Priority number, dateUS1994024911225.05.1994         Original published format: US 249112
[1997/11]
Filing languageEN
Procedural languageEN
PublicationType: A1 Application with search report
No.:WO9532302
Date:30.11.1995
Language:EN
[1995/51]
Type: A1 Application with search report 
No.:EP0760864
Date:12.03.1997
Language:EN
The application published by WIPO in one of the EPO official languages on 30.11.1995 takes the place of the publication of the European patent application.
[1997/11]
Type: B1 Patent specification 
No.:EP0760864
Date:24.11.2004
Language:EN
[2004/48]
Search report(s)International search report - published on:US30.11.1995
(Supplementary) European search report - dispatched on:EP21.12.1999
ClassificationIPC:C12P21/06, C12N15/00, C12N1/00, A01N61/00, C07K1/00, C07K16/00, C07H21/02, A61K39/395, A61K39/00, A61K39/002, G01N33/53
[1997/11]
CPC:
C07K14/70571 (EP,US); A61P31/00 (EP); A61P43/00 (EP);
A61K38/00 (EP,US); C12N2799/026 (EP,US)
Designated contracting statesAT,   BE,   CH,   DE,   DK,   ES,   FR,   GB,   GR,   IE,   IT,   LI,   LU,   NL,   PT,   SE [1997/11]
TitleGerman:FÜR DIE GLUTAMATABHÄNGIGEN CHLORIDKANÄLE KODIERENDE DNA[1997/11]
English:DNA ENCODING GLUTAMATE GATED CHLORIDE CHANNELS[1997/11]
French:ADN CODANT LES CANAUX A CHLORURE DEBLOQUES PAR GLUTAMATE[1997/11]
Entry into regional phase27.12.1996National basic fee paid 
27.12.1996Search fee paid 
27.12.1996Designation fee(s) paid 
27.12.1996Examination fee paid 
Examination procedure19.12.1995Request for preliminary examination filed
27.12.1996Examination requested  [1997/11]
30.01.2002Despatch of a communication from the examining division (Time limit: M06)
05.08.2002Reply to a communication from the examining division
18.11.2002Despatch of a communication from the examining division (Time limit: M06)
14.05.2003Reply to a communication from the examining division
13.01.2004Date of oral proceedings
28.01.2004Minutes of oral proceedings despatched
18.03.2004Communication of intention to grant the patent
28.09.2004Fee for grant paid
28.09.2004Fee for publishing/printing paid
Opposition(s)25.08.2005No opposition filed within time limit [2005/46]
Fees paidRenewal fee
02.06.1997Renewal fee patent year 03
02.06.1998Renewal fee patent year 04
31.05.1999Renewal fee patent year 05
31.05.2000Renewal fee patent year 06
31.05.2001Renewal fee patent year 07
31.05.2002Renewal fee patent year 08
07.05.2003Renewal fee patent year 09
05.05.2004Renewal fee patent year 10
Opt-out from the exclusive  Tooltip
competence of the Unified
Patent Court		 See the Register of the Unified Patent Court for opt-out data
Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court.
Lapses during opposition  TooltipAT24.11.2004
BE24.11.2004
CH24.11.2004
LI24.11.2004
NL24.11.2004
DK24.02.2005
GR24.02.2005
SE24.02.2005
PT24.04.2005
IE19.05.2005
LU19.05.2005
[2008/06]
Former [2007/26]AT24.11.2004
BE24.11.2004
CH24.11.2004
LI24.11.2004
NL24.11.2004
DK24.02.2005
GR24.02.2005
SE24.02.2005
IE19.05.2005
LU19.05.2005
Former [2007/16]AT24.11.2004
BE24.11.2004
CH24.11.2004
LI24.11.2004
NL24.11.2004
DK24.02.2005
GR24.02.2005
SE24.02.2005
IE19.05.2005
LU31.05.2005
Former [2006/25]AT24.11.2004
BE24.11.2004
CH24.11.2004
LI24.11.2004
NL24.11.2004
DK24.02.2005
GR24.02.2005
IE19.05.2005
Former [2006/14]AT24.11.2004
BE24.11.2004
CH24.11.2004
LI24.11.2004
NL24.11.2004
DK24.02.2005
GR24.02.2005
Former [2005/51]AT24.11.2004
BE24.11.2004
CH24.11.2004
LI24.11.2004
DK24.02.2005
GR24.02.2005
Former [2005/46]AT24.11.2004
CH24.11.2004
LI24.11.2004
DK24.02.2005
GR24.02.2005
Former [2005/36]AT24.11.2004
CH24.11.2004
LI24.11.2004
GR24.02.2005
Former [2005/26]CH24.11.2004
LI24.11.2004
GR24.02.2005
Former [2005/25]CH24.11.2004
LI24.11.2004
Documents cited:Search[A]WO9210583  (ZYMOGENETICS INC [US], et al) [A] 1-34 * abstract * * claims 1-38 *;
 [A]WO9219717  (BAYLOR COLLEGE MEDICINE [US], et al) [A] 1-34 * abstract * * page 1 - page 13 *;
 [E]WO9634940  (MERCK & CO INC [US], et al) [E] 7,9,10,12 * abstract ** claims 1-14 *;
 [XDA]  - ROHRER S.P., "Photoaffinity labelling of avermectin binding sites from Caernorhabditis elegan and Drosophila melanogaster", PROC. NATL. ACAD. SCI. USA, (199205), vol. 89, pages 4168 - 4172, XP002113577 [XD] 1-11,14-34 * the whole document * [A] 12,13

DOI:   http://dx.doi.org/10.1073/pnas.89.9.4168
 [PX]  - CULLY D.F. ET AL., "Cloning of an avermectin-sensitive glutamate-gated chloride channel from Caernorhabditis elegans", NATURE, (19941020), vol. 371, pages 707 - 711, XP002113578 [PX] 1-11,14-34 * the whole document *

DOI:   http://dx.doi.org/10.1038/371707a0
 [A]  - CULLY D F ET AL, "SOLUBILIZATION AND CHARACTERIZATION OF A HIGH AFFINITY IVERMECTIN BINDING SITE FROM CAENORHABDITIS ELEGANS", MOLECULAR PHARMACOLOGY,US,BALTIMORE, MD, vol. 40, no. 2, ISSN 0026-895X, page 326-332, XP002052916 [A] 1-34 * the whole document *
 [A]  - KANNER B.I., "Glutamate transporters from brain", FEBS LETTERS, (199306), vol. 325, no. 1-2, pages 95 - 99, XP002124431 [A] 1-34 * the whole document *

DOI:   http://dx.doi.org/10.1016/0014-5793(93)81421-U
 [A]  - MINAKAMI R. ET AL., "Molecular cloning and the functional expression of two isoforms of human metabotropic glutamate receptor subtype 5.", BIOCHEM. BIOPHYS. RES. COMMUN., (19940330), vol. 199, no. 3, pages 1136 - 1143, XP002124432 [A] 1-34 * the whole document *

DOI:   http://dx.doi.org/10.1006/bbrc.1994.1349
 [A]  - MROZIK H ET AL, "DISCOVERY OF NOVEL AVERMECTINS WITH UNPRECEDENTED INSECTICIDAL ACTIVITY", EXPERIENTIA,CH,BIRKHAUSER VERLAG. BASEL, vol. 45, no. 3, ISSN 0014-4754, page 315-316, XP000029339 [A] 15-34 * the whole document *

DOI:   http://dx.doi.org/10.1007/BF01951823
International search[YP]US5385831  (MULVIHILL EILEEN R [US], et al)
 [Y]  - MOLECULAR PHARMACOLOGY, Volume 40, Number 3, issued June 1991, ARENA et al., "Avermectin-Sensitive Chloride Currents Induced by Caenorhabditis Elegans RNA in Xenopus Oocytes", pages 368-374.
 [Y]  - MOLECULAR BRAIN RESEARCH, Volume 15, Number 3-4, issued October 1992, ARENA et al., "Expression of a Glutamate-Activated Chloride Current in Xenopus Oocytes Injected with Caenorhabditis Elegans RNA: Evidence for Modulation by Avermectin", pages 339-348.
 [Y]  - PARASITOLOGY TODAY, Volume 10, Number 1, issued January 1994, ARENA J.P., "Expression of Caenorhabditis Elegans mRNA in Xenopus Oocytes: A Model System to Study the Mechanism of Action of Avermectins", pages 35-37.
 [Y]  - E. HARLOW et al., "Antibodies: A Laboratory Manual", Published January 1988, by COLD SPRING HARBOR LABORATORY PRESS (N.Y.), pages 92-115.
 [Y]  - SCIENCE, Volume 241, issued 29 July 1988, JULIUS et al., "Molecular Characterization of a Functional cDNA Encoding the Serotonin 1c Receptor", pages 558-564.
 [Y]  - JOURNAL OF EXPERIMENTAL BIOLOGY, Volume 142, Number 0, issued January 1989, ZUFALL et al., "The Insecticide Avermectin B1a Activates a Chloride Channel in Crayfish Muscle Membrane", pages 191-205.
The EPO accepts no responsibility for the accuracy of data originating from other authorities; in particular, it does not guarantee that it is complete, up to date or fit for specific purposes.