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EP About this file: EP0767832

EP0767832 - CHIRAL SYNTHESIS OF 2-HYDROXY CARBOXYLIC ACIDS WITH A DEHYDROGENASE [Right-click to bookmark this link]
Status	The application is deemed to be withdrawn Status updated on 18.02.2005 Database last updated on 02.11.2024
Most recent event Tooltip	18.02.2005	Application deemed to be withdrawn	published on 06.04.2005 [2005/14]
Applicant(s)	For all designated states Genzyme Limited 37 Hollands Road Haverhill Suffolk CB9 8PU / GB
	[N/P]
Former [1997/16]	For all designated states Genzyme Limited 37 Hollands Road Haverhill Suffolk CB9 8PU / GB
Inventor(s)	01 / HOLBROOK, Joseph, John Sleight Farm Bath BA3 1HN / GB
	02 / WILLIS, Christine, Louise-University of Bristol School of Chemistry-Cantock's Close Bristol BS5 1TS / GB
	03 / JOHNSEN, Keyji 1 Chapel Green Lane Bristol BS6 6UA / GB
	04 / HATELEY, Martin, John-University of Bristol School of Chemistry-Cantock's Close Bristol BS8 1TS / GB
	[1997/16]
Representative(s)	Froud, Clive, et al Elkington and Fife LLP Prospect House 8 Pembroke Road Sevenoaks Kent TN13 1XR / GB
	[N/P]
Former [1997/16]	Froud, Clive, et al Elkington and Fife Prospect House 8 Pembroke Road Sevenoaks, Kent TN13 1XR / GB
Application number, filing date	95940911.1	07.07.1995
	[1997/16]
	WO1995EP02692
Priority number, date	GB19940013710	07.07.1994 Original published format: GB 9413710
	[1997/16]
Filing language	EN
Procedural language	EN
Publication	Type:	A1 Application with search report
	No.:	WO9601892
	Date:	25.01.1996
	Language:	EN
	[1996/05]
	Type:	A1 Application with search report
	No.:	EP0767832
	Date:	16.04.1997
	Language:	EN
	The application published by WIPO in one of the EPO official languages on 25.01.1996 takes the place of the publication of the European patent application.
	[1997/16]
Search report(s)	International search report - published on:	EP	25.01.1996
Classification	IPC:	C12N9/04, C12P7/42, C12N15/53	[1997/16]
	CPC:	C12N9/0006 (EP,US); C12P7/42 (EP,US)
Designated contracting states	AT, BE, CH, DE, DK, ES, FR, GB, GR, IE, IT, LI, LU, MC, NL, PT, SE [1997/16]
Title	German:	CHIRALE SYNTHESE VON 2-HYDROXYCARBONSÄUREN MIT EINER DEHYDROGENASE	[1997/16]
	English:	CHIRAL SYNTHESIS OF 2-HYDROXY CARBOXYLIC ACIDS WITH A DEHYDROGENASE	[1997/16]
	French:	SYNTHESE CHIRALE D'ACIDES 2-HYDROXYCARBOXYLIQUES AVEC UNE DESHYDROGENASE	[1997/16]
Entry into regional phase	07.01.1997	National basic fee paid
	07.01.1997	Designation fee(s) paid
	07.01.1997	Examination fee paid
Examination procedure	07.07.1995	Request for preliminary examination filed International Preliminary Examining Authority: EP
	07.01.1997	Examination requested [1997/16]
	06.09.2002	Despatch of a communication from the examining division (Time limit: M06)
	20.06.2003	Reply to a communication from the examining division
	19.05.2004	Despatch of a communication from the examining division (Time limit: M04)
	30.09.2004	Application deemed to be withdrawn, date of legal effect [2005/14]
	04.11.2004	Despatch of communication that the application is deemed to be withdrawn, reason: reply to the communication from the examining division not received in time [2005/14]
Request for further processing for:	20.06.2003	Request for further processing filed
	20.06.2003	Full payment received (date of receipt of payment) Request granted
	08.07.2003	Decision despatched
Fees paid	Renewal fee
	14.07.1997	Renewal fee patent year 03
	10.07.1998	Renewal fee patent year 04
	21.07.1999	Renewal fee patent year 05
	10.07.2000	Renewal fee patent year 06
	05.07.2001	Renewal fee patent year 07
	22.07.2002	Renewal fee patent year 08
	23.07.2003	Renewal fee patent year 09
	Penalty fee
	Additional fee for renewal fee
	31.07.2004	10 M06 Not yet paid
Opt-out from the exclusive Tooltip competence of the Unified Patent Court	See the Register of the Unified Patent Court for opt-out data
	Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court.
Cited in	International search	[A]EP0130288 (DEGUSSA [DE], et al) [A] 1 * claim - *
		[X] - DATABASE EMBL Empro:Ldhdhag. access No X 65222 DELCOUR , J. [X] 1-6 * '' NAD+ dependent D-2-hydroxyisocaproate dehydroge- nase Lactobacillus delbr.ssp.bulgaricus: * * Gene cloning and enzyme characterization'' *
		[ ] - EUR.J.BIOCHEM., vol. 224, pages 439 - 446
		[X] - NESSLER, SYLVIE ET AL, "Crystallization of D-lactate dehydrogenase from Lactobacillus bulgaricus", CHEMICAL ABSTRACTS, (19940411), vol. 120, no. 15, Database accession no. 186050, page 450 [X] 1,2,6 * abstract *
		[ ] - J. MOL. BIOL. (1994), 235(1), 370-1 CODEN: JMOBAK;ISSN: 0022-2836
		[X] - BERNARD, NATHALIE ET AL, "Cloning of the D-lactate dehydrogenase gene from Lactobacillus delbrueckii subsp. bulgaricus by complementation in Escherichia coli", FEBS LETT. (1991), 290(1-2), 61-4 CODEN: FEBLAL;ISSN: 0014-5793 [X] 1,2,6 * the whole document *
		[X] - SUNIL KOCHHAR ET AL., "Primary structure,physicochemical properties, and chemical modification of NAD+ -dependent D-lactate dehydrogenase.", JOURNAL OF BIOLOGICAL CHEMISTRY, MD US, (19920425), vol. 267, no. 12, pages 8499 - 8513 [X] 1,2,6 * the whole document *
		[X] - SUNIL KOCHHAR ET AL., "Cloning and overexpression of the Lactobacillus Bulgaricus NAD+ -dependent D-lactate dehydrogenase gene in Escherichia coli:Purification and characterization of the recombinant enzyme.", BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, ORLANDO, FL US, (19920615), vol. 185, no. 2, pages 705 - 712 [X] 1,2,6 * the whole document *
		[A] - RAGOUT, ALICIA ET AL, "Presence of an L(+)-lactate dehydrogenase in cells of Lactobacillus delbrueckii ssp. bulgaricus", CHEMICAL ABSTRACTS, (19890828), vol. 111, no. 9, Database accession no. 74501, page 421 [A] 1 * abstract *
		[ ] - BIOCHIMIE (1989), 71(5), 639-44 CODEN: BICMBE;ISSN: 0300-9084
		[PX] - BERNARD, NATHALIE ET AL, "D175 discriminates between NADH and NADPH in the coenzyme binding site of Lactobacillus delbrueckii subsp. bulgaricus D-lactate dehydrogenase", BIOCHEM. BIOPHYS. RES. COMMUN. (1995), 208(3), 895-900 CODEN: BBRCA9;ISSN: 0006-291X [PX] 1,2,6 * the whole document *

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