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Extract from the Register of European Patents

EP About this file: EP0745612

EP0745612 - Anti-idiotypic antibodies which induce an immune response against epidermal growth factor receptor [Right-click to bookmark this link]
StatusNo opposition filed within time limit
Status updated on  13.09.2002
Database last updated on 19.10.2024
Most recent event   Tooltip04.01.2008Lapse of the patent in a contracting state
New state(s): IT
published on 06.02.2008  [2008/06]
Applicant(s)For all designated states
Merck Patent GmbH
Frankfurter Strasse 250
64293 Darmstadt / DE
[N/P]
Former [1996/49]For all designated states
MERCK PATENT GmbH
Frankfurter Strasse 250
64293 Darmstadt / DE
Inventor(s)01 / Carceller, Ana
Taquigrafo Marti 6 2 2a
08028 Barcelona / ES
02 / Rosell, Elisabet
Enrique Granados, 43 3
08008 Barcelona / ES
03 / Gomez, Alicia
Josep Tarradellas, 116 7 2a
08029 Barcelona / ES
04 / Adan, Jaume
Pujol
28 Mataro / ES
05 / Piulats, Jaume
M. Quinti Mallofre'2
08030 Barcelona / ES
[1996/49]
Application number, filing date96107651.014.05.1996
[1996/49]
Priority number, dateEP1995010796726.05.1995         Original published format: EP 95107967
[1996/49]
Filing languageEN
Procedural languageEN
PublicationType: A1 Application with search report 
No.:EP0745612
Date:04.12.1996
Language:EN
[1996/49]
Type: B1 Patent specification 
No.:EP0745612
Date:07.11.2001
Language:EN
[2001/45]
Search report(s)(Supplementary) European search report - dispatched on:EP14.10.1996
ClassificationIPC:C07K16/42, A61K39/395
[1996/49]
CPC:
C07K16/4258 (EP); A61K38/00 (EP)
Designated contracting statesAT,   BE,   CH,   DE,   DK,   ES,   FR,   GB,   GR,   IE,   IT,   LI,   LU,   NL,   PT,   SE [1996/49]
Extension statesLT14.05.1996
LV14.05.1996
SI14.05.1996
TitleGerman:Antiidiotypische Antikörper die eine Immunantwort gegen den Rezeptor für epidermalen Wachstumsfaktor induzieren[1996/49]
English:Anti-idiotypic antibodies which induce an immune response against epidermal growth factor receptor[1996/49]
French:Anticorps anti-idiotypiques qui induisent une réponse immunitaire contre le récepteur de croissance épidermique[1996/49]
Examination procedure23.05.1997Examination requested  [1997/30]
11.08.2000Despatch of a communication from the examining division (Time limit: M04)
01.12.2000Reply to a communication from the examining division
18.04.2001Despatch of communication of intention to grant (Approval: Yes)
07.05.2001Communication of intention to grant the patent
13.07.2001Fee for grant paid
13.07.2001Fee for publishing/printing paid
Opposition(s)08.08.2002No opposition filed within time limit [2002/44]
Fees paidRenewal fee
11.05.1998Renewal fee patent year 03
12.05.1999Renewal fee patent year 04
15.05.2000Renewal fee patent year 05
14.05.2001Renewal fee patent year 06
Opt-out from the exclusive  Tooltip
competence of the Unified
Patent Court
See the Register of the Unified Patent Court for opt-out data
Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court.
Lapses during opposition  TooltipAT07.11.2001
BE07.11.2001
CH07.11.2001
FR07.11.2001
GR07.11.2001
IT07.11.2001
LI07.11.2001
NL07.11.2001
DK07.02.2002
PT07.02.2002
SE07.02.2002
DE08.02.2002
GB14.05.2002
IE14.05.2002
LU14.05.2002
ES30.05.2002
[2008/06]
Former [2006/14]AT07.11.2001
BE07.11.2001
CH07.11.2001
FR07.11.2001
GR07.11.2001
LI07.11.2001
NL07.11.2001
DK07.02.2002
PT07.02.2002
SE07.02.2002
DE08.02.2002
GB14.05.2002
IE14.05.2002
LU14.05.2002
ES30.05.2002
Former [2004/39]AT07.11.2001
BE07.11.2001
CH07.11.2001
GR07.11.2001
LI07.11.2001
NL07.11.2001
DK07.02.2002
PT07.02.2002
SE07.02.2002
DE08.02.2002
GB14.05.2002
IE14.05.2002
LU14.05.2002
ES30.05.2002
Former [2004/04]AT07.11.2001
BE07.11.2001
CH07.11.2001
GR07.11.2001
LI07.11.2001
NL07.11.2001
DK07.02.2002
PT07.02.2002
SE07.02.2002
DE08.02.2002
GB14.05.2002
IE14.05.2002
ES30.05.2002
Former [2003/46]AT07.11.2001
BE07.11.2001
CH07.11.2001
GR07.11.2001
LI07.11.2001
NL07.11.2001
DK07.02.2002
PT07.02.2002
SE07.02.2002
DE08.02.2002
GB14.05.2002
IE14.05.2002
Former [2003/30]AT07.11.2001
BE07.11.2001
CH07.11.2001
GR07.11.2001
LI07.11.2001
NL07.11.2001
PT07.02.2002
SE07.02.2002
DE08.02.2002
GB14.05.2002
IE14.05.2002
Former [2003/29]AT07.11.2001
BE07.11.2001
CH07.11.2001
GR07.11.2001
LI07.11.2001
NL07.11.2001
PT07.02.2002
SE07.02.2002
GB14.05.2002
IE14.05.2002
Former [2003/17]AT07.11.2001
BE07.11.2001
CH07.11.2001
GR07.11.2001
LI07.11.2001
NL07.11.2001
PT07.02.2002
SE07.02.2002
GB14.05.2002
Former [2003/09]AT07.11.2001
BE07.11.2001
CH07.11.2001
GR07.11.2001
LI07.11.2001
NL07.11.2001
PT07.02.2002
SE07.02.2002
Former [2003/06]BE07.11.2001
CH07.11.2001
GR07.11.2001
LI07.11.2001
NL07.11.2001
PT07.02.2002
SE07.02.2002
Former [2003/01]CH07.11.2001
GR07.11.2001
LI07.11.2001
PT07.02.2002
SE07.02.2002
Former [2002/49]GR07.11.2001
PT07.02.2002
SE07.02.2002
Former [2002/48]PT07.02.2002
SE07.02.2002
Former [2002/26]SE07.02.2002
Documents cited:Search[X]EP0586002  (CENTRO DE IMMUNOLOGIA MOLECULAR) [X] 1-10 * page 7, line 44 - page 8, line 5 * * claim 1 *;
 [DA]WO9215683  (MERCK PATENT GMBH) [DA] 1-10 * example - * * claim - *;
 [A]  - O. MERIMSKY ET AL., "Antigens and antibodies in malignant melanoma.", TUMOUR BIOLOGY, BASEL, SWITZERLAND, (1994), vol. 15, no. 4, pages 188 - 202, XP000579858 [A] 1-10 * the whole document *
 [DA]  - C. KETTLEBOROUGH ET AL., "Humanization of a mouse monoclonal antibody by CDR-grafting: the importance of framework residues on loop conformation.", PROTEIN ENGINEERING, OXFORD, GB, (199110), vol. 4, no. 7, pages 773 - 783, XP002012218 [DA] 1-10 * abstract *
 [DA]  - U. RODECK ET AL., "Tumor growth modulation by a monoclonal antibody to the epidermal growth factor receptor: immunologically mediated and effector cell-independent effects.", CANCER RESEARCH, BALTIMORE, MD, USA, (19870715), vol. 47, no. 14, pages 3692 - 3696, XP002012219 [DA] 1-10 * abstract *
 [DA]  - E. SUAREZ ET AL., IMMUNOLOGIA, MILANO, ITALY, (1993), vol. 12, page 122, XP002012220 [DA] 1-10 * the whole document *
 [A]  - M. TSUJISAKI ET AL., "The analysis of internal image-bearing anti-idiotypic monoclonal antibody in relation to carcinoembryonic antigen.", THE JOURNAL OF IMMUNOLOGY, BALTIMORE, MD, USA, (19930115), vol. 150, no. 2, pages 508 - 516, XP002012221 [A] 1-10 * abstract *
 [A]  - K. STEINER ET AL., "Distribution of humanized mab 425 (EMD 62 000) in rats and specific localization in tumour-bearing nude mice.", CELLULAR AND MOLECULAR IMMUNOLOGY, NEW YORK, NY, USA, (199502), vol. 41, no. 1, pages 179 - 184, XP002012222 [A] 1-10 * abstract *
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