EP0745612 - Anti-idiotypic antibodies which induce an immune response against epidermal growth factor receptor [Right-click to bookmark this link] | Status | No opposition filed within time limit Status updated on 13.09.2002 Database last updated on 19.10.2024 | Most recent event Tooltip | 04.01.2008 | Lapse of the patent in a contracting state New state(s): IT | published on 06.02.2008 [2008/06] | Applicant(s) | For all designated states Merck Patent GmbH Frankfurter Strasse 250 64293 Darmstadt / DE | [N/P] |
Former [1996/49] | For all designated states MERCK PATENT GmbH Frankfurter Strasse 250 64293 Darmstadt / DE | Inventor(s) | 01 /
Carceller, Ana Taquigrafo Marti 6 2 2a 08028 Barcelona / ES | 02 /
Rosell, Elisabet Enrique Granados, 43 3 08008 Barcelona / ES | 03 /
Gomez, Alicia Josep Tarradellas, 116 7 2a 08029 Barcelona / ES | 04 /
Adan, Jaume Pujol 28 Mataro / ES | 05 /
Piulats, Jaume M. Quinti Mallofre'2 08030 Barcelona / ES | [1996/49] | Application number, filing date | 96107651.0 | 14.05.1996 | [1996/49] | Priority number, date | EP19950107967 | 26.05.1995 Original published format: EP 95107967 | [1996/49] | Filing language | EN | Procedural language | EN | Publication | Type: | A1 Application with search report | No.: | EP0745612 | Date: | 04.12.1996 | Language: | EN | [1996/49] | Type: | B1 Patent specification | No.: | EP0745612 | Date: | 07.11.2001 | Language: | EN | [2001/45] | Search report(s) | (Supplementary) European search report - dispatched on: | EP | 14.10.1996 | Classification | IPC: | C07K16/42, A61K39/395 | [1996/49] | CPC: |
C07K16/4258 (EP);
A61K38/00 (EP)
| Designated contracting states | AT, BE, CH, DE, DK, ES, FR, GB, GR, IE, IT, LI, LU, NL, PT, SE [1996/49] | Extension states | LT | 14.05.1996 | LV | 14.05.1996 | SI | 14.05.1996 | Title | German: | Antiidiotypische Antikörper die eine Immunantwort gegen den Rezeptor für epidermalen Wachstumsfaktor induzieren | [1996/49] | English: | Anti-idiotypic antibodies which induce an immune response against epidermal growth factor receptor | [1996/49] | French: | Anticorps anti-idiotypiques qui induisent une réponse immunitaire contre le récepteur de croissance épidermique | [1996/49] | Examination procedure | 23.05.1997 | Examination requested [1997/30] | 11.08.2000 | Despatch of a communication from the examining division (Time limit: M04) | 01.12.2000 | Reply to a communication from the examining division | 18.04.2001 | Despatch of communication of intention to grant (Approval: Yes) | 07.05.2001 | Communication of intention to grant the patent | 13.07.2001 | Fee for grant paid | 13.07.2001 | Fee for publishing/printing paid | Opposition(s) | 08.08.2002 | No opposition filed within time limit [2002/44] | Fees paid | Renewal fee | 11.05.1998 | Renewal fee patent year 03 | 12.05.1999 | Renewal fee patent year 04 | 15.05.2000 | Renewal fee patent year 05 | 14.05.2001 | Renewal fee patent year 06 |
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Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court. | Lapses during opposition Tooltip | AT | 07.11.2001 | BE | 07.11.2001 | CH | 07.11.2001 | FR | 07.11.2001 | GR | 07.11.2001 | IT | 07.11.2001 | LI | 07.11.2001 | NL | 07.11.2001 | DK | 07.02.2002 | PT | 07.02.2002 | SE | 07.02.2002 | DE | 08.02.2002 | GB | 14.05.2002 | IE | 14.05.2002 | LU | 14.05.2002 | ES | 30.05.2002 | [2008/06] |
Former [2006/14] | AT | 07.11.2001 | |
BE | 07.11.2001 | ||
CH | 07.11.2001 | ||
FR | 07.11.2001 | ||
GR | 07.11.2001 | ||
LI | 07.11.2001 | ||
NL | 07.11.2001 | ||
DK | 07.02.2002 | ||
PT | 07.02.2002 | ||
SE | 07.02.2002 | ||
DE | 08.02.2002 | ||
GB | 14.05.2002 | ||
IE | 14.05.2002 | ||
LU | 14.05.2002 | ||
ES | 30.05.2002 | ||
Former [2004/39] | AT | 07.11.2001 | |
BE | 07.11.2001 | ||
CH | 07.11.2001 | ||
GR | 07.11.2001 | ||
LI | 07.11.2001 | ||
NL | 07.11.2001 | ||
DK | 07.02.2002 | ||
PT | 07.02.2002 | ||
SE | 07.02.2002 | ||
DE | 08.02.2002 | ||
GB | 14.05.2002 | ||
IE | 14.05.2002 | ||
LU | 14.05.2002 | ||
ES | 30.05.2002 | ||
Former [2004/04] | AT | 07.11.2001 | |
BE | 07.11.2001 | ||
CH | 07.11.2001 | ||
GR | 07.11.2001 | ||
LI | 07.11.2001 | ||
NL | 07.11.2001 | ||
DK | 07.02.2002 | ||
PT | 07.02.2002 | ||
SE | 07.02.2002 | ||
DE | 08.02.2002 | ||
GB | 14.05.2002 | ||
IE | 14.05.2002 | ||
ES | 30.05.2002 | ||
Former [2003/46] | AT | 07.11.2001 | |
BE | 07.11.2001 | ||
CH | 07.11.2001 | ||
GR | 07.11.2001 | ||
LI | 07.11.2001 | ||
NL | 07.11.2001 | ||
DK | 07.02.2002 | ||
PT | 07.02.2002 | ||
SE | 07.02.2002 | ||
DE | 08.02.2002 | ||
GB | 14.05.2002 | ||
IE | 14.05.2002 | ||
Former [2003/30] | AT | 07.11.2001 | |
BE | 07.11.2001 | ||
CH | 07.11.2001 | ||
GR | 07.11.2001 | ||
LI | 07.11.2001 | ||
NL | 07.11.2001 | ||
PT | 07.02.2002 | ||
SE | 07.02.2002 | ||
DE | 08.02.2002 | ||
GB | 14.05.2002 | ||
IE | 14.05.2002 | ||
Former [2003/29] | AT | 07.11.2001 | |
BE | 07.11.2001 | ||
CH | 07.11.2001 | ||
GR | 07.11.2001 | ||
LI | 07.11.2001 | ||
NL | 07.11.2001 | ||
PT | 07.02.2002 | ||
SE | 07.02.2002 | ||
GB | 14.05.2002 | ||
IE | 14.05.2002 | ||
Former [2003/17] | AT | 07.11.2001 | |
BE | 07.11.2001 | ||
CH | 07.11.2001 | ||
GR | 07.11.2001 | ||
LI | 07.11.2001 | ||
NL | 07.11.2001 | ||
PT | 07.02.2002 | ||
SE | 07.02.2002 | ||
GB | 14.05.2002 | ||
Former [2003/09] | AT | 07.11.2001 | |
BE | 07.11.2001 | ||
CH | 07.11.2001 | ||
GR | 07.11.2001 | ||
LI | 07.11.2001 | ||
NL | 07.11.2001 | ||
PT | 07.02.2002 | ||
SE | 07.02.2002 | ||
Former [2003/06] | BE | 07.11.2001 | |
CH | 07.11.2001 | ||
GR | 07.11.2001 | ||
LI | 07.11.2001 | ||
NL | 07.11.2001 | ||
PT | 07.02.2002 | ||
SE | 07.02.2002 | ||
Former [2003/01] | CH | 07.11.2001 | |
GR | 07.11.2001 | ||
LI | 07.11.2001 | ||
PT | 07.02.2002 | ||
SE | 07.02.2002 | ||
Former [2002/49] | GR | 07.11.2001 | |
PT | 07.02.2002 | ||
SE | 07.02.2002 | ||
Former [2002/48] | PT | 07.02.2002 | |
SE | 07.02.2002 | ||
Former [2002/26] | SE | 07.02.2002 | Documents cited: | Search | [X]EP0586002 (CENTRO DE IMMUNOLOGIA MOLECULAR) [X] 1-10 * page 7, line 44 - page 8, line 5 * * claim 1 *; | [DA]WO9215683 (MERCK PATENT GMBH) [DA] 1-10 * example - * * claim - *; | [A] - O. MERIMSKY ET AL., "Antigens and antibodies in malignant melanoma.", TUMOUR BIOLOGY, BASEL, SWITZERLAND, (1994), vol. 15, no. 4, pages 188 - 202, XP000579858 [A] 1-10 * the whole document * | [DA] - C. KETTLEBOROUGH ET AL., "Humanization of a mouse monoclonal antibody by CDR-grafting: the importance of framework residues on loop conformation.", PROTEIN ENGINEERING, OXFORD, GB, (199110), vol. 4, no. 7, pages 773 - 783, XP002012218 [DA] 1-10 * abstract * | [DA] - U. RODECK ET AL., "Tumor growth modulation by a monoclonal antibody to the epidermal growth factor receptor: immunologically mediated and effector cell-independent effects.", CANCER RESEARCH, BALTIMORE, MD, USA, (19870715), vol. 47, no. 14, pages 3692 - 3696, XP002012219 [DA] 1-10 * abstract * | [DA] - E. SUAREZ ET AL., IMMUNOLOGIA, MILANO, ITALY, (1993), vol. 12, page 122, XP002012220 [DA] 1-10 * the whole document * | [A] - M. TSUJISAKI ET AL., "The analysis of internal image-bearing anti-idiotypic monoclonal antibody in relation to carcinoembryonic antigen.", THE JOURNAL OF IMMUNOLOGY, BALTIMORE, MD, USA, (19930115), vol. 150, no. 2, pages 508 - 516, XP002012221 [A] 1-10 * abstract * | [A] - K. STEINER ET AL., "Distribution of humanized mab 425 (EMD 62 000) in rats and specific localization in tumour-bearing nude mice.", CELLULAR AND MOLECULAR IMMUNOLOGY, NEW YORK, NY, USA, (199502), vol. 41, no. 1, pages 179 - 184, XP002012222 [A] 1-10 * abstract * |