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Extract from the Register of European Patents

EP About this file: EP0776970

EP0776970 - Stable enzyme composition comprising a thermostable nucleic acid polymerase enzyme [Right-click to bookmark this link]
StatusPatent maintained as amended
Status updated on  21.06.2013
Database last updated on 29.10.2024
Most recent event   Tooltip21.06.2013Patent maintained (B2 publication)published on 24.07.2013  [2013/30]
Applicant(s)For all designated states
F. Hoffmann-La Roche AG
Postfach 3255
4002 Basel / CH
[2008/15]
Former [1997/23]For all designated states
F. Hoffmann-La Roche AG
Postfach 3255
4002 Basel / CH
Inventor(s)01 / Saiki, Randy
1737 Alameda Ave
Alameda, CA 94501 / US
02 / Stoffel, Susanne
935 Galvin Drive
El Cerrito, CA 94530 / US
03 / Gelfland, David
6208 Chelton Drive
Oakland, CA 94611 / US
[1997/23]
Representative(s)Vossius & Partner Patentanwälte Rechtsanwälte mbB
Siebertstrasse 3
81675 München / DE
[N/P]
Former [2013/30]Vossius & Partner
Siebertstrasse 4
81675 München / DE
Former [2008/35]Vossius & Partner
Siebertstrasse 3
81675 München / DE
Former [1997/23]VOSSIUS & PARTNER
Siebertstrasse 4
81675 München / DE
Application number, filing date96119077.421.08.1987
[1997/23]
Priority number, dateUS1986089951322.08.1986         Original published format: US 899513
US1986089924122.08.1986         Original published format: US 899241
US1987006364717.06.1987         Original published format: US 63647
US1987006350917.06.1987         Original published format: US 63509
[1997/23]
Filing languageEN
Procedural languageEN
PublicationType: A1 Application with search report 
No.:EP0776970
Date:04.06.1997
Language:EN
[1997/23]
Type: B1 Patent specification 
No.:EP0776970
Date:09.04.2008
Language:EN
[2008/15]
Type: B2 New European patent specification 
No.:EP0776970
Date:24.07.2013
Language:EN
[2013/30]
Search report(s)(Supplementary) European search report - dispatched on:EP09.04.1997
ClassificationIPC:C12N9/12, C12N9/96, C12N15/00, C12P19/34, C12Q1/68
[1997/23]
CPC:
C12P19/34 (EP); C12N15/00 (KR); C12N9/1252 (EP);
C12N9/1276 (EP); C12P21/00 (KR); C12Q1/68 (KR);
C12Q1/686 (EP) (-)
C-Set:
C12Q1/686, C12Q2527/125 (EP)
Designated contracting statesAT,   BE,   CH,   DE,   ES,   FR,   GB,   GR,   IT,   LI,   LU,   NL,   SE [1997/23]
TitleGerman:Stabile Enzymzusammensetzung, die eine thermostabile Nukleinsäurepolymerase enthält[1997/23]
English:Stable enzyme composition comprising a thermostable nucleic acid polymerase enzyme[1997/23]
French:Composition d'enzyme stable contenant une polymérase d'acide nucléique thermostable[1997/23]
Biological materialThis application mentions deposited biological material, check the file for details
Examination procedure27.12.1996Examination requested  [1997/23]
14.11.2000Request for accelerated examination filed
10.05.2002Despatch of a communication from the examining division (Time limit: M04)
10.05.2002Decision about request for accelerated examination - accepted: Yes
29.10.2004Despatch of communication that the application is deemed to be withdrawn, reason: reply to the communication from the examining division not received in time
04.01.2005Reply to a communication from the examining division
07.08.2006Despatch of a communication from the examining division (Time limit: M04)
13.12.2006Reply to a communication from the examining division
28.09.2007Communication of intention to grant the patent
05.01.2008Observations by third parties
11.01.2008Fee for grant paid
11.01.2008Fee for publishing/printing paid
Parent application(s)   TooltipEP87307433.0  / EP0258017
Opposition(s)Opponent(s)01  09.01.2009  21.01.2009  ADMISSIBLE
NEW ENGLAND BIOLABS, INC.
240 County Road
Ipswich, MA 01938-2723 / US
Opponent's representative
König, Gregor Sebastian
König-Szynka-Tilmann-von Renesse
Patentanwälte Partnerschaft mbB
Postfach 11 09 46
40509 Düsseldorf / DE
 [N/P]
Former [2011/39]
Opponent(s)01  09.01.2009  21.01.2009  ADMISSIBLE
NEW ENGLAND BIOLABS, INC.
240 County Road
Ipswich, MA 01938-2723 / US
Opponent's representative
König, Gregor Sebastian
König Szynka Tilmann von Renesse Patentanwälte Partnerschaft Lohengrinstrasse 11
40549 Düsseldorf / DE
Former [2009/08]
Opponent(s)01  09.01.2009   
NEW ENGLAND BIOLABS, INC.
240 County Road
Ipswich, MA 01938-2723 / US
Opponent's representative
Davies, Jonathan Mark
Reddie & Grose 16 Theobalds Road
London WC1X 8PL / GB
17.02.2009Invitation to proprietor to file observations on the notice of opposition
26.06.2009Reply of patent proprietor to notice(s) of opposition
10.03.2011Date of oral proceedings
21.06.2011Despatch of interlocutory decision in opposition
21.06.2011Despatch of minutes of oral proceedings
15.11.2012Legal effect of interlocutory decision in opposition
15.03.2013Despatch of communication that the patent will be maintained as amended
10.06.2013Fee for printing new specification paid
Appeal following opposition22.08.2011Appeal received No.  T1705/11
02.11.2011Statement of grounds filed
15.11.2012Result of appeal procedure: appeal of the proprietor was rejected
01.08.2011Appeal received No.  T1705/11
28.10.2011Statement of grounds filed
15.11.2012Result of appeal procedure: appeal of the proprietor was rejected
15.11.2012Date of oral proceedings
27.11.2012Minutes of the oral proceedings despatched
Request for further processing for:04.01.2005Request for further processing filed
04.01.2005Full payment received (date of receipt of payment)
Request granted
20.01.2005Decision despatched
Fees paidRenewal fee
27.12.1996Renewal fee patent year 03
27.12.1996Renewal fee patent year 04
27.12.1996Renewal fee patent year 05
27.12.1996Renewal fee patent year 06
27.12.1996Renewal fee patent year 07
27.12.1996Renewal fee patent year 08
27.12.1996Renewal fee patent year 09
27.12.1996Renewal fee patent year 10
23.08.1997Renewal fee patent year 11
10.08.1998Renewal fee patent year 12
11.08.1999Renewal fee patent year 13
16.08.2000Renewal fee patent year 14
14.08.2001Renewal fee patent year 15
14.08.2002Renewal fee patent year 16
13.08.2003Renewal fee patent year 17
06.08.2004Renewal fee patent year 18
08.08.2005Renewal fee patent year 19
07.08.2006Renewal fee patent year 20
Opt-out from the exclusive  Tooltip
competence of the Unified
Patent Court		 See the Register of the Unified Patent Court for opt-out data
Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court.
Lapses during opposition  TooltipAT09.04.2008
BE09.04.2008
IT09.04.2008
NL10.04.2008
SE09.07.2008
GR10.07.2008
ES20.07.2008
FR30.01.2009
[2011/25]
Former [2010/05]AT09.04.2008
BE09.04.2008
IT09.04.2008
NL10.04.2008
SE09.07.2008
ES20.07.2008
FR30.01.2009
Former [2009/30]AT09.04.2008
BE09.04.2008
NL10.04.2008
SE09.07.2008
ES20.07.2008
FR30.01.2009
Former [2009/14]AT09.04.2008
BE09.04.2008
NL10.04.2008
SE09.07.2008
ES20.07.2008
Former [2009/07]AT09.04.2008
NL10.04.2008
SE09.07.2008
ES20.07.2008
Former [2008/50]AT09.04.2008
NL10.04.2008
ES20.07.2008
Former [2008/47]NL10.04.2008
ES20.07.2008
Former [2008/27]NL10.04.2008
Documents cited:Search[Y]US4305837  (KAMINSKY GEORGE J, et al) [Y] 1 * column 1, line 55 - column 2, line 11 *;
 [DY]  - A. CHIEN ET AL., "Deoxyribonucleic acid polymerase from the extreme thermophile Thermus Aquaticus", JOURNAL OF BACTERIOLOGY, BALTIMORE US, (197608), vol. 127, no. 3, pages 1550 - 1557, XP002027712 [DY] 1 * the whole document *
 [A]  - K. MARTINEK ET AL., "The stabilisation of enzymes-a key factor in the practical application of biocatalysis", RUSSIAN CHEMICAL REVIEWS (USPEKHI KHIMII), LONDON GB, (1980), vol. 49, no. 5, pages 385 - 403, XP002027713 [A] 1

DOI:   http://dx.doi.org/10.1070/RC1980v049n05ABEH002466
by applicantEP0063879
 US4358535
 US4399216
 US4419446
 US4458066
 EP0164054
 US4582789
 US4601978
 EP0196864
 US4617261
 EP0200362
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    - BUTTIN, KORNBERG, J. BIOL. CHEM., (1966), vol. 241, pages 5419 - 5427
    - KALEDIN ET AL., BIOKHYMIYA, (1980), vol. 45, pages 644 - 651
    - A. CHIEN ET AL., J. BACTERIOL., (1976), vol. 127, pages 1550 - 1557
    - SAIKI ET AL., SCIENCE, (1985), vol. 230, pages 1350 - 1354
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    - T. OSHIMA, ARCH. MICROBIOL., (1978), vol. 117, pages 189 - 196
    - BOLIVAR ET AL., GENE, (1977), vol. 2, page 95
    - CHANG ET AL., NATURE, (1977), vol. 198, page 1056
    - GOEDDEL ET AL., NUCLEIC ACIDS RES., (1980), vol. 8, page 4057
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    - M.J. HOLLAND ET AL., J. BIOL. CHEM., (1981), vol. 256, page 1385
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    - D.W. MILLER ET AL., D.W. MILLER ET AL., J.K. SETLOW ET AL., Genetic Engineering, PLENUM PUBLISHING, (1986), vol. 8, pages 277 - 297
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    - APLLICATION CONTAINS STILL MORE REFERENCES
other   - SUELTER C.H., DELUCA M., "HOW TO PREVENT LOSSES OF PROTEIN BY ADSORPTION TO GLASS AND PLASTIC", ANAL. BIOCHEM., (1983), vol. 135, pages 112 - 119, XP009031248

DOI:   http://dx.doi.org/10.1016/0003-2697(83)90738-8
    - DAVID BRUCE EDGAR, "DNA polymerase from an extreme thermophile: thermus aquaticus", MASTER THESIS, (1974), pages 1 - 93 + COVER, CONTENT, XP003019522
    - CLARENCE H. SUELTER, A practical guide to enzymology, USA, JOHN WILEY AND SONS, (1985), ISBN 0-471-86431-5, XP003019523
The EPO accepts no responsibility for the accuracy of data originating from other authorities; in particular, it does not guarantee that it is complete, up to date or fit for specific purposes.