EP0821588 - LEVOBUPIVACAINE AND ITS USE AS AN ANAESTHETIC IN PREGNANT WOMEN [Right-click to bookmark this link] | Status | No opposition filed within time limit Status updated on 23.04.2004 Database last updated on 03.09.2024 | Most recent event Tooltip | 23.04.2004 | No opposition filed within time limit | published on 09.06.2004 [2004/24] | Applicant(s) | For all designated states Darwin Discovery Limited 208 Bath Road Slough Berks SL1 3WE / GB | [N/P] |
Former [2003/04] | For all designated states Darwin Discovery Limited 208 Bath Road Slough Berks SL1 3WE / GB | ||
Former [1999/04] | For all designated states Darwin Discovery Limited Cambridge Science Park, Milton Road Cambridge CB4 4WE / GB | ||
Former [1998/06] | For all designated states Chiroscience Limited Cambridge Science Park, Milton Road Cambridge CB4 4WE / GB | Inventor(s) | 01 /
BARDSLEY, Hazel, Judith Chiroscience Limited Cambridge Science Park Milton Road Cambridge CB4 4WE / GB | 02 /
GRISTWOOD, Robert, William Chiroscience Limited Cambridge Science Park Milton Road Cambridge CB4 4WE / GB | [1998/06] | Representative(s) | Perry, Robert Edward, et al Gill Jennings & Every LLP The Broadgate Tower 20 Primrose Street London EC2A 2ES / GB | [N/P] |
Former [1998/06] | Perry, Robert Edward, et al GILL JENNINGS & EVERY Broadgate House 7 Eldon Street London EC2M 7LH / GB | Application number, filing date | 96910087.4 | 15.04.1996 | [1998/06] | WO1996GB00912 | Priority number, date | GB19950007677 | 13.04.1995 Original published format: GB 9507677 | US19950549408 | 27.10.1995 Original published format: US 549408 | [1998/06] | Filing language | EN | Procedural language | EN | Publication | Type: | A2 Application without search report | No.: | WO9632109 | Date: | 17.10.1996 | Language: | EN | [1996/46] | Type: | A2 Application without search report | No.: | EP0821588 | Date: | 04.02.1998 | Language: | EN | The application published by WIPO in one of the EPO official languages on 17.10.1996 takes the place of the publication of the European patent application. | [1998/06] | Type: | B1 Patent specification | No.: | EP0821588 | Date: | 18.06.2003 | Language: | EN | [2003/25] | Search report(s) | International search report - published on: | EP | 13.02.1997 | Classification | IPC: | A61K31/445, A61P23/02 | [2002/20] | CPC data not yet available |
Former IPC [1998/06] | A61K31/445 | Designated contracting states | AT, BE, CH, DE, DK, ES, FI, FR, GB, GR, IE, IT, LI, LU, NL, PT, SE [1998/06] | Title | German: | LEVOBUPIVACAIN UND DESSEN VERWENDUNG ALS ANÄSTHETIKUM BEI SCHWANGEREN FRAUEN | [1998/06] | English: | LEVOBUPIVACAINE AND ITS USE AS AN ANAESTHETIC IN PREGNANT WOMEN | [1998/06] | French: | LEVOBUPIVACAINE ET SON UTILISATION COMME ANESTHESIQUE CHEZ LA FEMME ENCEINTE | [1998/06] | Entry into regional phase | 31.10.1997 | National basic fee paid | 31.10.1997 | Designation fee(s) paid | 31.10.1997 | Examination fee paid | Examination procedure | 24.10.1996 | Request for preliminary examination filed International Preliminary Examining Authority: EP | 31.10.1997 | Examination requested [1998/06] | 29.05.2001 | Despatch of a communication from the examining division (Time limit: M06) | 07.12.2001 | Reply to a communication from the examining division | 31.05.2002 | Despatch of communication of intention to grant (Approval: Yes) | 09.12.2002 | Communication of intention to grant the patent | 21.02.2003 | Fee for grant paid | 21.02.2003 | Fee for publishing/printing paid | Opposition(s) | 19.03.2004 | No opposition filed within time limit [2004/24] | Fees paid | Renewal fee | 14.04.1998 | Renewal fee patent year 03 | 14.04.1999 | Renewal fee patent year 04 | 13.04.2000 | Renewal fee patent year 05 | 12.04.2001 | Renewal fee patent year 06 | 12.04.2002 | Renewal fee patent year 07 | 14.04.2003 | Renewal fee patent year 08 |
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Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court. | Cited in | International search | [DPX]WO9510276 (CHIROSCIENCE LTD [GB], et al) [DPX] 1-13 * the whole document *; | [DPX]WO9510277 (CHIROSCIENCE LTD [GB], et al) [DPX] 1-13 * the whole document *; | [X] - REYNOLDS, F., "In defence of Bupivacaine", INTERNATIONAL JOURNAL OD OBSTETRIC ANALGESIA, (1995), vol. 4, no. 2, pages 93 - 108, XP000613009 [X] 1-3 * the whole document * * especially page 107, line 54, righthand column-page 108, line 13, lefthand column * DOI: http://dx.doi.org/10.1016/0959-289X(95)82999-Q | [DA] - DENSON, D.D. ET AL, "Enantiomer-specific effects of an intravenously administered arrhythmogenic dose of bupivacaine on neurons of the nucleus tractus solitarius and the cardiovascular system in the anesthetized rat", REGIONAL ANAESTHESIA, (1992), vol. 17, pages 311 - 316, XP000610923 [DA] 1-13 * the whole document * | [DA] - GRISTWOOD, R. ET AL, "Reduced cardiotoxicity of levobupivacaine compared with racemic bupivacaine (Marcaine): new clinical evidence", EXPERT OPINION ON INVESTIGATIONAL DRUGS, (199411), vol. 3, no. 11, pages 1209 - 1212, XP000610836 [DA] 1-13 * the whole document * | [DA] - VANHOUTTE, F. ET AL, "Stereoselective effects of the enantiomers of bupivacaine on the electrophysiological properties of the guinea-pig papillary muscle", BRITISH JOURNAL OF PHARMACOLOGY, (1991), vol. 103, pages 1275 - 1281, XP000610827 [DA] 1-13 * the whole document * | [A] - RUTTEN, A.J. ET AL, "Tissue distribution of bupivacaine enantiomers in sheep", CHIRALITY, (1993), vol. 5, no. 7, pages 485 - 491, XP000610881 [A] 1-13 * the whole document * DOI: http://dx.doi.org/10.1002/chir.530050702 | [A] - ABERG, G., "Toxicological and local anaesthetic effects of optically active isomers of two local anaesthetic compounds", ACTA PHARMACOLOGICA ET TOXICOLOGICA, (1972), vol. 31, pages 273 - 286, XP000610878 [A] 1-13 * the whole document * | [A] - KUHNERT, B.R. ET AL, "Bupivacaine disposition in mother, fetus and neonate", FEDERATION PROCEEDINGS, (1981), vol. 40, no. 31, page 684, XP002020663 [A] 1-13 * abstract * |