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Extract from the Register of European Patents

EP About this file: EP0828843

EP0828843 - RECOMBINANT HEREGULINS AND THEIR BIOLOGICAL FUNCTIONS UPON RECEPTOR ACTIVATION [Right-click to bookmark this link]
StatusThe application is deemed to be withdrawn
Status updated on  25.04.2003
Database last updated on 05.10.2024
Most recent event   Tooltip25.07.2008Change - representativepublished on 27.08.2008  [2008/35]
Applicant(s)For all designated states
Bristol-Myers Squibb Company
Route 206 and Province Line Road
Princeton, NJ 08543 / US
[N/P]
Former [1998/12]For all designated states
BRISTOL-MYERS SQUIBB COMPANY
P.O. Box 4000
Princeton, NJ 08543-4000 / US
Inventor(s)01 / CULOUSCOU, Jean-Michel
39, rue de Verdun
F-78110 Le Vésinet / FR
02 / CARLTON, Gary, W.
Apartment 403-411 West Republician
Seattle, WA 98119 / US
03 / ARUFFO, Alejandro, A.
1012 Spruce Street
Edmonds, WA 98020 / US
[1998/12]
Representative(s)Vossius & Partner Patentanwälte Rechtsanwälte mbB
Siebertstrasse 3
81675 München / DE
[N/P]
Former [2008/35]Vossius & Partner
Siebertstrasse 3
81675 München / DE
Former [1998/12]VOSSIUS & PARTNER
Siebertstrasse 4
81675 München / DE
Application number, filing date96915791.614.05.1996
[1998/12]
WO1996US06861
Priority number, dateUS1995044186316.05.1995         Original published format: US 441863
[1998/12]
Filing languageEN
Procedural languageEN
PublicationType: A1 Application with search report
No.:WO9636720
Date:21.11.1996
Language:EN
[1996/51]
Type: A1 Application with search report 
No.:EP0828843
Date:18.03.1998
Language:EN
The application published by WIPO in one of the EPO official languages on 21.11.1996 takes the place of the publication of the European patent application.
[1998/12]
Search report(s)International search report - published on:EP21.11.1996
ClassificationIPC:C12N15/62, C12N15/12, C07K14/475, A61K38/18
[1998/12]
CPC:
C07K14/4756 (EP); A61P43/00 (EP); C07K14/475 (EP);
A61K38/00 (EP); C07K2319/02 (EP)
Designated contracting statesAT,   BE,   CH,   DE,   DK,   ES,   FI,   FR,   GB,   GR,   IE,   IT,   LI,   LU,   MC,   NL,   PT,   SE [1998/12]
TitleGerman:REKOMBINANTE HEREGULINE UND IHRE BIOLOGISCHE FUNKTIONEN NACH REZEPTORAKTIVIERUNG[1998/12]
English:RECOMBINANT HEREGULINS AND THEIR BIOLOGICAL FUNCTIONS UPON RECEPTOR ACTIVATION[1998/12]
French:HEREGULINES DE RECOMBINAISON ET LEURS FONCTIONS BIOLOGIQUES LORS DE L'ACTIVATION D'UN RECEPTEUR[1998/12]
Entry into regional phase16.12.1997National basic fee paid 
16.12.1997Designation fee(s) paid 
16.12.1997Examination fee paid 
Examination procedure06.12.1996Request for preliminary examination filed
International Preliminary Examining Authority: US
16.12.1997Examination requested  [1998/12]
12.07.2002Despatch of a communication from the examining division (Time limit: M04)
25.11.2002Application deemed to be withdrawn, date of legal effect  [2003/24]
08.01.2003Despatch of communication that the application is deemed to be withdrawn, reason: reply to the communication from the examining division not received in time  [2003/24]
Fees paidRenewal fee
16.12.1997Renewal fee patent year 03
12.05.1999Renewal fee patent year 04
15.05.2000Renewal fee patent year 05
14.05.2001Renewal fee patent year 06
14.05.2002Renewal fee patent year 07
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Cited inInternational search[Y]EP0329175  (TOSOH CORP [JP]) [Y] 1,2 * page 3, line 4 - line 10 *;
 [DX]  - W.E.HOLMES ET AL., "Identification of heregulin, a specific activator of p185erbB2", SCIENCE, LANCASTER, PA US, (19920522), vol. 256, pages 1205 - 1210, XP002015659 [DX] 20 * page 1209, column L, line 15 - line 24 *

DOI:   http://dx.doi.org/10.1126/science.256.5060.1205
 [YA]  - A.ARUFFO ET AL., "CD44 is the principal cell surface receptor for hyaluronate", CELL, NA US, (19900629), vol. 61, pages 1303 - 1313, XP002015660 [Y] 1,2 * see page 1310: CD5-IgG1 Vector Construction * [A] 3-10

DOI:   http://dx.doi.org/10.1016/0092-8674(90)90694-A
 [PX]  - J-M CULOUSCOU ET AL., "HER4 receptor activation and phosphorylation of Shc proteins by recombinant heregulin-Fc fusion proteins", JOURNAL OF BIOLOGICAL CHEMISTRY, MD US, (19950526), vol. 270, no. 21, pages 12857 - 12863, XP002015661 [PX] 1-20 * the whole document *

DOI:   http://dx.doi.org/10.1074/jbc.270.21.12857
The EPO accepts no responsibility for the accuracy of data originating from other authorities; in particular, it does not guarantee that it is complete, up to date or fit for specific purposes.