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Extract from the Register of European Patents

EP About this file: EP0827544

EP0827544 - MULTIMERIC PROTEINS [Right-click to bookmark this link]
StatusPatent revoked
Status updated on  14.07.2006
Database last updated on 25.09.2024
Most recent event   Tooltip04.01.2008Lapse of the patent in a contracting state
New state(s): IT, PT		published on 06.02.2008  [2008/06]
Applicant(s)For all designated states
MorphoSys AG
Am Klopferspitz 19
82152 Martinsried / DE
[1999/12]
Former [1998/11]For all designated states
MORPHOSYS GESELLSCHAFT FÜR PROTEINOPTIMIERUNG mbH
Frankfurter Ring 193a
80807 München / DE
Inventor(s)01 / PACK, Peter
Franz-Wolter-Strasse 4/III
D-81925 Oberföhring / DE
02 / HOESS, Adolf
Am Waldeck 2
D-83629 Weyarn / DE
 [2004/34]
Former [1998/11]01 / PACK, Peter
Franz-Wolter-Strasse 4/III
D-81925 Oberföhring / DE
02 / HOESS, Adolf
Wirtsbreite 21
D-83672 Warngau / DE
Representative(s)Vossius & Partner Patentanwälte Rechtsanwälte mbB
Siebertstrasse 3
81675 München / DE
[N/P]
Former [1998/11]VOSSIUS & PARTNER
Postfach 86 07 67
81634 München / DE
Application number, filing date96916159.523.05.1996
[1998/11]
WO1996EP02230
Priority number, dateEP1995010791423.05.1995         Original published format: EP 95107914
[1998/11]
Filing languageEN
Procedural languageEN
PublicationType: A2 Application without search report
No.:WO9637621
Date:28.11.1996
Language:EN
[1996/52]
Type: A2 Application without search report 
No.:EP0827544
Date:11.03.1998
Language:EN
The application published by WIPO in one of the EPO official languages on 28.11.1996 takes the place of the publication of the European patent application.
[1998/11]
Type: B1 Patent specification 
No.:EP0827544
Date:18.08.2004
Language:EN
[2004/34]
Search report(s)International search report - published on:EP03.01.1997
ClassificationIPC:C12N15/62, C07K19/00, C07K14/82, C07K14/52, C07K14/78, C07K14/47, C07K16/18, C07K16/28, C12N1/21, C12N1/19
[1998/11]
CPC:
C07K16/18 (EP); A61P35/00 (EP); A61P43/00 (EP);
C07K16/28 (EP); C07K16/44 (EP); C07K19/00 (EP);
C12N15/62 (EP); A61K38/00 (EP); C07K2319/02 (EP);
C07K2319/70 (EP); C07K2319/75 (EP) (-)
Designated contracting statesAT,   BE,   CH,   DE,   DK,   ES,   FI,   FR,   GB,   GR,   IE,   IT,   LI,   LU,   MC,   NL,   PT,   SE [1998/11]
TitleGerman:MULTIMERE PROTEINE[1998/11]
English:MULTIMERIC PROTEINS[1998/11]
French:PROTEINES MULTIMERES[1998/11]
Entry into regional phase28.11.1997National basic fee paid 
28.11.1997Designation fee(s) paid 
28.11.1997Examination fee paid 
Examination procedure19.12.1996Request for preliminary examination filed
International Preliminary Examining Authority: EP
28.11.1997Examination requested  [1998/11]
05.09.2002Despatch of a communication from the examining division (Time limit: M04)
14.01.2003Reply to a communication from the examining division
09.02.2004Communication of intention to grant the patent
21.06.2004Fee for grant paid
21.06.2004Fee for publishing/printing paid
Opposition(s)Opponent(s)01  18.05.2005    ADMISSIBLE
Borean Pharma A/S
Gustav Wieds Vej 10
8000 Aarhus C / DK
Opponent's representative
Inspicos P/S
Agern Allé 24
2970 Hørsholm / DK
 [N/P]
Former [2005/28]
Opponent(s)01  18.05.2005    ADMISSIBLE
Borean Pharma A/S
Gustav Wieds Vej 10
8000 Aarhus C / DK
Opponent's representative
Inspicos A/S
Böge Allé 5, P.O. Box 45
2970 Hörsholm / DK
20.07.2005Invitation to proprietor to file observations on the notice of opposition
02.03.2006Reply of patent proprietor to notice(s) of opposition
14.03.2006Despatch of communication that the patent will be revoked
24.03.2006Legal effect of revocation of patent [2006/33]
Fees paidRenewal fee
29.05.1998Renewal fee patent year 03
28.05.1999Renewal fee patent year 04
30.05.2000Renewal fee patent year 05
31.05.2001Renewal fee patent year 06
31.05.2002Renewal fee patent year 07
30.05.2003Renewal fee patent year 08
28.05.2004Renewal fee patent year 09
Opt-out from the exclusive  Tooltip
competence of the Unified
Patent Court		 See the Register of the Unified Patent Court for opt-out data
Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court.
Lapses during opposition  TooltipFI18.08.2004
FR18.08.2004
IT18.08.2004
NL18.08.2004
DK18.11.2004
GR18.11.2004
SE18.11.2004
ES29.11.2004
PT18.01.2005
IE23.05.2005
LU23.05.2005
MC31.05.2005
[2008/06]
Former [2007/30]FI18.08.2004
FR18.08.2004
NL18.08.2004
DK18.11.2004
GR18.11.2004
SE18.11.2004
ES29.11.2004
IE23.05.2005
LU23.05.2005
MC31.05.2005
Former [2007/29]FI18.08.2004
FR18.08.2004
NL18.08.2004
DK18.11.2004
GR18.11.2004
SE18.11.2004
ES29.11.2004
IE23.05.2005
MC31.05.2005
Former [2006/32]FI18.08.2004
FR18.08.2004
NL18.08.2004
DK18.11.2004
GR18.11.2004
SE18.11.2004
ES29.11.2004
IE23.05.2005
Former [2006/25]FI18.08.2004
NL18.08.2004
DK18.11.2004
GR18.11.2004
SE18.11.2004
ES29.11.2004
IE23.05.2005
FR19.08.2005
Former [2006/14]FI18.08.2004
NL18.08.2004
DK18.11.2004
GR18.11.2004
SE18.11.2004
ES29.11.2004
FR19.08.2005
Former [2006/13]FI18.08.2004
NL18.08.2004
DK18.11.2004
GR18.11.2004
SE18.11.2004
ES29.11.2004
Former [2005/23]FI18.08.2004
DK18.11.2004
GR18.11.2004
SE18.11.2004
ES29.11.2004
Former [2005/22]FI18.08.2004
DK18.11.2004
GR18.11.2004
SE18.11.2004
Former [2005/18]FI18.08.2004
GR18.11.2004
SE18.11.2004
Former [2005/11]FI18.08.2004
SE18.11.2004
Former [2005/10]SE18.11.2004
Cited inInternational search[DY]WO9315210  (MERCK PATENT GMBH [DE]) [DY] 1-3,12-16,25-41 * page 10 - page 13; examples 1-4 *;
 [PX]WO9613583  (MORPHOSYS PROTEINOPTIMIERUNG [DE], et al) [PX] 1,25-37 * figure 2 *;
 [X]  - DUBEL S ET AL, "Bifunctional and multimeric complexes of streptavidin fused to single chain antibodies (scFv).", J IMMUNOL METHODS, JAN 27 1995, 178 (2) P201-9, NETHERLANDS, XP000608189 [X] 1,25-41 * the whole document *

DOI:   http://dx.doi.org/10.1016/0022-1759(94)00257-W
 [PX]  - KIPRIYANOV SM ET AL, "Single-chain antibody streptavidin fusions: tetrameric bifunctional scFv-complexes with biotin binding activity and enhanced affinity to antigen.", HUM ANTIBODIES HYBRIDOMAS, 1995, 6 (3) P93-101, UNITED STATES, XP000607119 [PX] 1,25-41 * figure 5 *
 [Y]  - PACK P ET AL, "Tetravalent miniantibodies with high avidity assembling in Escherichia coli.", J MOL BIOL, FEB 10 1995, 246 (1) P28-34, ENGLAND, XP000607470 [Y] 1-7,12-16,25-41 * the whole document *

DOI:   http://dx.doi.org/10.1006/jmbi.1994.0062
 [DY]  - EFIMOV VP ET AL, "The thrombospondin-like chains of cartilage oligomeric matrix protein are assembled by a five-stranded alpha-helical bundle between residues 20 and 83", FEBS LETTERS, AMSTERDAM NL, (1994), vol. 341, pages 54 - 58, XP002017642 [DY] 1-7,12-16,25-41 * the whole document *

DOI:   http://dx.doi.org/10.1016/0014-5793(94)80239-4
 [DY]  - LAI CK ET AK, "Crystal structure of recombinant human platelet factor 4", BIOCHEMISTRY, EASTON, PA US, (1994), vol. 33, pages 8361 - 8366, XP002017643 [DY] 1-7,12-16,25-41 * page 4 *

DOI:   http://dx.doi.org/10.1021/bi00253a012
 [DY]  - SAKAMOTO H ET AL, "Specific sequences from the carboxyl terminus of human p53 gene product form anti-parallel tetramers in solution.", PROC NATL ACAD SCI U S A, SEP 13 1994, 91 (19) P8974-8, UNITED STATES, XP000608191 [DY] 1-3,12-16,25-41 * abstract *

DOI:   http://dx.doi.org/10.1073/pnas.91.19.8974
 [DY]  - JEFFREY PD ET AL, "Crystal structure of the tetramerization domain of the p53 tumor suppressor at 1.7 angstroms.", SCIENCE, MAR 10 1995, 267 (5203) P1498-502, UNITED STATES, XP000608194 [DY] 1-3,12-16,25-41 * abstract *

DOI:   http://dx.doi.org/10.1126/science.7878469
The EPO accepts no responsibility for the accuracy of data originating from other authorities; in particular, it does not guarantee that it is complete, up to date or fit for specific purposes.