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Extract from the Register of European Patents

EP About this file: EP0828851

EP0828851 - TRIPEPTIDYLPEPTIDASE INHIBITORS [Right-click to bookmark this link]
StatusNo opposition filed within time limit
Status updated on  26.05.2006
Database last updated on 31.08.2024
Most recent event   Tooltip11.07.2008Change - representativepublished on 13.08.2008  [2008/33]
Applicant(s)For all designated states
INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM)
101, rue de Tolbiac
75654 Paris Cédex 13 / FR
For all designated states
BIOPROJET
30, rue des Francs-Bourgeois
75003 Paris / FR
[N/P]
Former [2005/29]For all designated states
INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM)
101, rue de Tolbiac
75654 Paris Cédex 13 / FR
For all designated states
BIOPROJET
30, rue des Francs-Bourgeois
75003 Paris / FR
Former [2004/15]For all designated states
INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM)
101, rue de Tolbiac
75654 Paris Cédex 13 / FR
For all designated states
BIOPROJET
30, rue des Francs-Bourgeois
75003 Paris / FR
Former [1998/12]For all designated states
INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM)
101, rue de Tolbiac
75654 Paris Cédex 13 / FR
Inventor(s)01 / ROSE, Christiane
20, place Henri-IV
F-78320 Le Mesnil-Saint-Denis / FR
02 / VARGAS, Froylan
2 ter, rue d'Alésia
F-75014 Paris / FR
03 / BOURGEAT, Pierre
71 bis, boulevard Arago
F-75013 Paris / FR
04 / SCHWARTZ, Jean-Charles
9, villa Seurat
F-75014 Paris / FR
05 / BISHOP, Paul, Beaumont
2 Fairbridge Road
London N19 3HZ / GB
06 / BAMBAL, Ramesh, Babarao
802 Elmway Circle
Blue Bell, PA 19422 / US
07 / GANELLIN, Charon, Robin
Kinwood, Briary Wood End
Welwyn, Herts AL6 0TD / GB
08 / LEBLOND, Bertrand
10, rue de Fontenelle
F-76000 Rouen / FR
09 / MOORE, Andrew, N., J.
240 Powell Avenue, Apartment 3
Ottawa, Ontario K1S 2A5 / CA
10 / CHAN, Suzanne
42 Royal Oak Road, Bexleyhreath
Ken t DA6 7HG / GB
11 / LIHUA, Zhao
25 Ambler Road
London N4 2QT / GB
[1998/28]
Former [1998/12]01 / ROSE, Christiane
20, place Henri-IV
F-78320 Le Mesnil-Saint-Denis / FR
02 / VARGAS, Froylan
2 ter, rue d'Alésia
F-75014 Paris / FR
03 / BOURGEAT, Pierre
71 bis, boulevard Arago
F-75013 Paris / FR
04 / SCHWARTZ, Jean-Charles
9, villa Seurat
F-75014 Paris / FR
05 / BISHOP, Paul, Beaumont
2 Fairbridge Road
London N19 3HZ / GB
06 / BAMBAL, Ramesh, Babarao
2436 Redbud Lane, No A
Lawrence, KS 66046 / US
07 / GANELLIN, Charon, Robin
Kinwood, Briary Wood End
Welwyn, Herts AL6 0TD / GB
08 / LEBLOND, Bertrand
10, rue de Fontenelle
F-76000 Rouen / FR
09 / MOORE, Andrew, N., J.
Hebrew - University of Jerusalem
91904 Jerusalem / IL
10 / CHAN, Suzanne
42 Royal Oak Road, Bexleyhreath
Ken t DA6 7HG / GB
11 / LIHUA, Zhao
25 Ambler Road
London N4 2QT / GB
Representative(s)Bernasconi, Jean Raymond, et al
Cabinet Lavoix 2, Place d'Estienne d'Orves
75441 Paris Cedex 09 / FR
[N/P]
Former [2008/33]Bernasconi, Jean Raymond, et al
Cabinet Lavoix 2, Place d'Estienne d'Orves
75441 Paris Cedex 09 / FR
Former [1998/12]Bernasconi, Jean, et al
c/o Cabinet Lavoix, 2, Place d'Estienne d'Orves
75441 Paris Cédex / FR
Application number, filing date96916181.909.05.1996
[1998/12]
WO1996FR00700
Priority number, dateFR1995000548909.05.1995         Original published format: FR 9505489
[1998/12]
Filing languageFR
Procedural languageFR
PublicationType: A2 Application without search report
No.:WO9635805
Date:14.11.1996
Language:FR
[1996/50]
Type: A2 Application without search report 
No.:EP0828851
Date:18.03.1998
Language:FR
The application published by WIPO in one of the EPO official languages on 14.11.1996 takes the place of the publication of the European patent application.
[1998/12]
Type: B1 Patent specification 
No.:EP0828851
Date:20.07.2005
Language:FR
[2005/29]
Search report(s)International search report - published on:EP30.01.1997
ClassificationIPC:C12Q1/37, C07K5/062, A61K38/05
[1998/12]
CPC:
C07K5/06052 (EP,US); A61P1/00 (EP); A61P21/00 (EP);
A61P25/00 (EP); A61P25/16 (EP); A61P25/18 (EP);
A61P25/24 (EP); A61P3/00 (EP); A61P3/04 (EP);
C07D209/42 (EP,US); C07K5/06026 (EP,US); C07K5/06191 (EP,US);
C12Q1/37 (EP,US); A61K38/00 (EP,US); G01N2333/595 (EP,US) (-)
Designated contracting statesAT,   BE,   CH,   DE,   DK,   ES,   FI,   FR,   GB,   GR,   IE,   IT,   LI,   LU,   MC,   NL,   PT,   SE [1998/12]
TitleGerman:TRIPEPTIDYLPEPTIDASE-INHIBITOREN[1998/12]
English:TRIPEPTIDYLPEPTIDASE INHIBITORS[1998/12]
French:INHIBITEURS DE TRIPEPTIDYLPEPTIDASES[1998/12]
Entry into regional phase06.11.1997National basic fee paid 
06.11.1997Designation fee(s) paid 
06.11.1997Examination fee paid 
Examination procedure25.11.1996Request for preliminary examination filed
International Preliminary Examining Authority: EP
06.11.1997Examination requested  [1998/12]
10.06.1999Despatch of a communication from the examining division (Time limit: M06)
13.12.1999Reply to a communication from the examining division
16.08.2000Despatch of a communication from the examining division (Time limit: M06)
30.01.2001Reply to a communication from the examining division
05.11.2001Despatch of a communication from the examining division (Time limit: M06)
30.04.2002Reply to a communication from the examining division
11.02.2003Despatch of a communication from the examining division (Time limit: M06)
11.08.2003Reply to a communication from the examining division
14.12.2004Communication of intention to grant the patent
14.04.2005Fee for grant paid
14.04.2005Fee for publishing/printing paid
Opposition(s)21.04.2006No opposition filed within time limit [2006/26]
Fees paidRenewal fee
06.11.1997Renewal fee patent year 03
25.05.1999Renewal fee patent year 04
22.05.2000Renewal fee patent year 05
21.05.2001Renewal fee patent year 06
15.05.2002Renewal fee patent year 07
15.05.2003Renewal fee patent year 08
17.05.2004Renewal fee patent year 09
17.05.2005Renewal fee patent year 10
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Cited inInternational search[X]DE2727670  (HOFFMANN LA ROCHE) [X] 7-9,12,17,20,21,25,26 * page 27, line 11 - line 19 *;
 [X]DE2728593  (HOFFMANN LA ROCHE) [X] 7-9,12,17,20,21,25,26 * page 42, line 7 - line 14 *;
 [A]FR2460292  (RICHTER GEDEON VEGYESZET [HU]) [A] 50;
 [X]FR2510990  (SPOFA VEREINIGTE PHARMA WERKE [CS]) [X] 7-9,12,17,20,21,25,26 * examples 3,7 *;
 [X]AT389517B  (HOECHST AG [DE]) [X] 7-9,12,17,20,21,25,26 * example 2B *;
 [A]US5159060  (KINDER DAVID H [US], et al) [A] 7,8,19,22,28,30,31,37,38 * the whole document *;
 [A]WO9308259  (NEW ENGLAND MEDICAL CENTER INC [US], et al) [A] 1-50* the whole document *;
 [X]  - WILSON, C. ET AL, "Purification and characterization of tripeptidylpeptidase-II from post-mortem human brain", NEUROCHEM. RES. (1993), 18(7), 743-9 CODEN: NEREDZ;ISSN: 0364-3190, XP000562808 [X] 1-6 * the whole document *
 [DX]  - C. ROSE ET AL, "A serine peptidase responsible for the inactivation of endogenous cholecystokinin in brain", PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF USA, WASHINGTON US, vol. 85, pages 8326 - 8330, XP002018477 [DX] 1,4-6 * the whole document *
 [X]  - B. TOMKINSON, "Characterization of cDNA for murine tripeptidyl-peptidase II reveals alternative splicing", BIOCHEMICAL JOURNAL, vol. 304, pages 517 - 523, XP000562825 [X] 2,3 * the whole document *
 [X]  - B. TOMKINSON AND A-K JONSSON, "Characterization of cDNA for human tripeptidyl peptidase II", BIOCHEMISTRY, vol. 30, pages 168 - 174, XP000561825 [X] 2,3 * the whole document *
 [DX]  - R-M BALÖW ET AL, "Purification, substrate specificity, and classification of tripeptidyl peptidase II", JOURNAL OF BIOLOGICAL CHEMISTRY, MD US, vol. 261, no. 5, pages 2409 - 2417, XP002018480 [DX] 2,3 * the whole document *
 [A]  - TOMKINSON, BIRGITTA ET AL, "Use of a dehydroalanine-containing peptide as an efficient inhibitor of tripeptidyl peptidase II", ARCH. BIOCHEM. BIOPHYS. (1994), 314(2), 276-9 CODEN: ABBIA4;ISSN: 0003-9861, XP000562811 [A] 4-7 * the whole document *

DOI:   http://dx.doi.org/10.1006/abbi.1994.1442
 [PX]  - C.ROSE E.A., "Characterization and inhibition of a CCK-inactivating serine protease", NATURE, LONDON GB, (19960404), vol. 380, pages 403 - 409, XP002018482 [PX] 1-50 * the whole document *
Examination   - LIFE SCIENCES, (1984), vol. 34, pages 67 - 72
    - J. CLIN. PSYCHIATRY, (199110), vol. 52, no. 10, pages 21 - 28
    - NEUROSCIENCE LETTERS, (1991), vol. 131, pages 129 - 134
    - BRAIN RESEARCH, (1982), vol. 243, pages 176 - 179
    - AM. JOURN. MEDICAL GENETICS, (2002), vol. 114, pages 479 - 482
    - BIOL. PSYCHIATRY, (1993), vol. 34, pages 781 - 790
    - PSYCHOLOGICAL MEDICINE, (1992), vol. 22, pages 37 - 43
The EPO accepts no responsibility for the accuracy of data originating from other authorities; in particular, it does not guarantee that it is complete, up to date or fit for specific purposes.