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Extract from the Register of European Patents

EP About this file: EP0850300

EP0850300 - METHOD OF MODULATING GENE EXPRESSION WITH REDUCED IMMUNOSTIMULATORY RESPONSE [Right-click to bookmark this link]
StatusNo opposition filed within time limit
Status updated on  11.08.2000
Database last updated on 13.07.2024
Most recent event   Tooltip11.08.2000No opposition filed within time limitpublished on 27.09.2000 [2000/39]
Applicant(s)For all designated states
HYBRIDON, Inc.
155 Fortune Boulevard
Milford, MA 01757 / US
[N/P]
Former [1999/41]For all designated states
HYBRIDON, INC.
155 Fortune Boulevard
Milford, MA 01757 / US
Former [1999/26]For all designated states
Hybridon, Inc.
155 Fortune Boulevard
Milford, MA 01757 / US
Former [1998/27]For all designated states
HYBRIDON, Inc.
620 Memorial Drive
Cambridge, MA 02139 / US
Inventor(s)01 / AGRAWAL, Sudhir
61 Lamplighter Drive
Shrewsbury, MA 01545 / US
02 / TEMSAMANI, Jamal
16 Dartmouth Street
Worcester, MA 01604 / US
03 / ZHAO, Qiuyan
Apartment 160 67 Frank Street
Worcester, MA 01604 / US
[1998/27]
Representative(s)Vossius, Volker, et al
ZSP Patentanwälte PartG mbB
Radlkoferstrasse 2
81373 München / DE
[N/P]
Former [1998/27]Vossius, Volker, Dr., et al
Dr. Volker Vossius, Patentanwaltskanzlei - Rechtsanwaltskanzlei, Holbeinstrasse 5
81679 München / DE
Application number, filing date96923709.809.07.1996
[1998/27]
WO1996US11439
Priority number, dateUS1995051153604.08.1995         Original published format: US 511536
[1998/27]
Filing languageEN
Procedural languageEN
PublicationType: A1 Application with search report
No.:WO9706253
Date:20.02.1997
Language:EN
[1997/09]
Type: A1 Application with search report 
No.:EP0850300
Date:01.07.1998
Language:EN
The application published by WIPO in one of the EPO official languages on 20.02.1997 takes the place of the publication of the European patent application.
[1998/27]
Type: B1 Patent specification 
No.:EP0850300
Date:13.10.1999
Language:EN
[1999/41]
Search report(s)International search report - published on:EP20.02.1997
ClassificationIPC:C12N15/11, A61K31/70, A61K48/00
[1998/27]
CPC:
A61K31/7125 (EP,US); A61P31/00 (EP); A61P35/00 (EP);
C07H21/00 (EP,US)
Designated contracting statesAT,   BE,   CH,   DE,   DK,   ES,   FI,   FR,   GB,   GR,   IE,   IT,   LI,   LU,   MC,   NL,   PT,   SE [1998/27]
TitleGerman:METHODE ZUR MODULATION DER GENEXPRESSION MIT REDUZIERTER IMMUNSTIMULIERENDER WIRKUNG[1998/27]
English:METHOD OF MODULATING GENE EXPRESSION WITH REDUCED IMMUNOSTIMULATORY RESPONSE[1998/27]
French:PROCEDE DE MODULATION DE L'EXPRESSION D'UN GENE PROVOQUANT UNE REPONSE IMMUNOSTIMULATRICE REDUITE[1998/27]
Entry into regional phase26.02.1998National basic fee paid 
26.02.1998Designation fee(s) paid 
26.02.1998Examination fee paid 
Examination procedure03.03.1997Request for preliminary examination filed
International Preliminary Examining Authority: EP
26.02.1998Examination requested  [1998/27]
26.02.1998Request for accelerated examination filed
03.08.1998Despatch of communication of intention to grant (Approval: No)
03.08.1998Decision about request for accelerated examination - accepted: Yes
30.11.1998Despatch of communication of intention to grant (Approval: later approval)
17.12.1998Communication of intention to grant the patent
18.02.1999Fee for grant paid
18.02.1999Fee for publishing/printing paid
Opposition(s)14.07.2000No opposition filed within time limit [2000/39]
Fees paidRenewal fee
03.07.1998Renewal fee patent year 03
08.07.1999Renewal fee patent year 04
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Cited inInternational search[PX]  - Q. ZHAO ET AL., "Effect of different chemically modified oligodeoxynucleotides on immune stimulation", BIOCHEMICAL PHARMACOLOGY, (1996), vol. 51, pages 173 - 182, XP002019729 [PX] 1-19 *see the whole article*
 [PX]  - A.M. KRIEG ET AL., "Oligodeoxynucleotide modifications determine the magnitude of B cell stimulation by CpG motifs", ANTISENSE AND NUCLEIC ACID DRUG DEVELOPMENT, (1996), vol. 6, pages 133 - 139, XP002019730 [PX] 1-19 *see the whole article*
 [Y]  - D.S. PISETSKY & C. REICH, "Stimulation of in vitro proliferation of murine lymphocytes by sythetic oilgodeoxynucleotides", MOLECULAR BIOLOGY REPORTS, (1993), vol. 18, pages 217 - 221, XP002019731 [Y] 1-19 *see the whole article*
 [Y]  - L. ZHOU ET AL., "Synthesis of phopshorothioate-methylphosphonate oligonucleotide co-polymers", NUCLEIC ACIDS RESEARCH, (1994), vol. 22, no. 3, pages 453 - 456, XP002019732 [Y] 1-19 *see the whole article*
The EPO accepts no responsibility for the accuracy of data originating from other authorities; in particular, it does not guarantee that it is complete, up to date or fit for specific purposes.