EP0851918 - STRATEGY FOR SUPPRESSING THE EXPRESSION OF AN ENDOGENEOUS GENE BY USING COMPOUNDS THAT ARE ABLE TO BIND TO THE NON-CODING REGIONS OF THE GENE TO BE SUPPRESSED [Right-click to bookmark this link] | Status | No opposition filed within time limit Status updated on 11.12.2009 Database last updated on 02.11.2024 | Most recent event Tooltip | 15.08.2014 | Lapse of the patent in a contracting state | published on 17.09.2014 [2014/38] | Applicant(s) | For all designated states Optigen Patents Limited The Smurfit Institute of Genetics Trinity College Dublin Dublin 2 / IE | [2008/52] |
Former [2005/05] | For all designated states Optigen Patents Limited Department of Genetics Trinity College Dublin Dublin 2 / IE | ||
Former [1998/28] | For all designated states Provost, Fellows and Scholars of the College of the Holy and Undivided Trinity of Queen Elizabeth near Dublin Trinity College Dublin, Dublin 2 / IE | Inventor(s) | 01 /
FARRAR, Gwenyth, Jane 9 The Crescent, Monkstown D20 County Dublin / IE | 02 /
HUMPHRIES, Peter 5 Holmwood, Cabinteely D15 County Dublin / IE | 03 /
KENNA, Paul, Francis 176 New Cabra Road Dublin 7 / IE | [1998/28] | Representative(s) | Main, Malcolm Charles, et al Murgitroyd & Company Scotland House 165-169 Scotland Street Glasgow G5 8PL / GB | [N/P] |
Former [2009/48] | Main, Malcolm Charles, et al Murgitroyd & Company Scotland House 165-169 Scotland Street Glasgow G5 8PL / GB | ||
Former [2006/18] | Main, Malcolm Charles, et al Murgitroyd & Company Scotland House 165-169 Scotland Street Glasgow, G5 8PL / GB | ||
Former [1998/28] | Pattullo, Norman, et al Murgitroyd and Company 373 Scotland Street Glasgow G5 8QA / GB | Application number, filing date | 96931887.2 | 23.09.1996 | [1998/28] | WO1996GB02357 | Priority number, date | GB19950019299 | 21.09.1995 Original published format: GB 9519299 | [1998/28] | Filing language | EN | Procedural language | EN | Publication | Type: | A2 Application without search report | No.: | WO9711169 | Date: | 27.03.1997 | Language: | EN | [1997/14] | Type: | A2 Application without search report | No.: | EP0851918 | Date: | 08.07.1998 | Language: | EN | The application published by WIPO in one of the EPO official languages on 27.03.1997 takes the place of the publication of the European patent application. | [1998/28] | Type: | B1 Patent specification | No.: | EP0851918 | Date: | 04.02.2009 | Language: | EN | [2009/06] | Search report(s) | International search report - published on: | EP | 12.06.1997 | Classification | IPC: | C12N15/11, C12N9/00, C12N15/85, A61K48/00 | [1998/28] | CPC: |
C12N15/113 (EP,US);
C07K14/47 (EP,US);
C07K14/78 (EP,US);
A61K38/00 (EP,US);
A61K48/00 (EP,US);
C12N2310/121 (EP,US);
| Designated contracting states | AT, BE, CH, DE, DK, ES, FI, FR, GB, GR, IE, IT, LI, LU, MC, NL, PT, SE [1998/28] | Title | German: | STRATEGIE ZUR UNTERDRUCKUNG DER EXPRESSION EINES ENDOGENEN GENES DURCH VERWENDUNG VON VERBINDUNGEN, DIE AN DIE NICHT-KODIERENDEN REGIONEN DES ZU HEMMENDEN GENES BINDEN KÖNNEN | [1998/28] | English: | STRATEGY FOR SUPPRESSING THE EXPRESSION OF AN ENDOGENEOUS GENE BY USING COMPOUNDS THAT ARE ABLE TO BIND TO THE NON-CODING REGIONS OF THE GENE TO BE SUPPRESSED | [1998/28] | French: | STRATEGIE PERMETTANT DE SUPPRIMER L'EXPRESSION D'UN GENE ENDOGENE EN UTILISANT DES COMPOSES CAPABLES DE SE LIER AUX REGIONS NON CODANTES D'UN GENE A SUPPRIMER | [1998/28] | Entry into regional phase | 17.04.1998 | National basic fee paid | 17.04.1998 | Designation fee(s) paid | 17.04.1998 | Examination fee paid | Examination procedure | 21.04.1997 | Request for preliminary examination filed International Preliminary Examining Authority: EP | 17.04.1998 | Examination requested [1998/28] | 24.09.2003 | Despatch of a communication from the examining division (Time limit: M08) | 20.09.2004 | Reply to a communication from the examining division | 02.05.2005 | Despatch of a communication from the examining division (Time limit: M06) | 16.12.2005 | Despatch of communication that the application is deemed to be withdrawn, reason: reply to the communication from the examining division not received in time | 23.02.2006 | Reply to a communication from the examining division | 15.11.2007 | Despatch of a communication from the examining division (Time limit: M06) | 19.05.2008 | Reply to a communication from the examining division | 22.07.2008 | Communication of intention to grant the patent | 20.11.2008 | Fee for grant paid | 20.11.2008 | Fee for publishing/printing paid | Opposition(s) | 05.11.2009 | No opposition filed within time limit [2010/02] | Request for further processing for: | 23.02.2006 | Request for further processing filed | 23.02.2006 | Full payment received (date of receipt of payment) Request granted | 13.03.2006 | Decision despatched | 20.09.2004 | Request for further processing filed | 20.09.2004 | Full payment received (date of receipt of payment) Request granted | 04.10.2004 | Decision despatched | Fees paid | Renewal fee | 25.09.1998 | Renewal fee patent year 03 | 26.08.1999 | Renewal fee patent year 04 | 13.09.2000 | Renewal fee patent year 05 | 12.09.2001 | Renewal fee patent year 06 | 12.09.2002 | Renewal fee patent year 07 | 12.09.2003 | Renewal fee patent year 08 | 23.08.2004 | Renewal fee patent year 09 | 05.09.2005 | Renewal fee patent year 10 | 08.09.2006 | Renewal fee patent year 11 | 05.09.2007 | Renewal fee patent year 12 | 05.09.2008 | Renewal fee patent year 13 |
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Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court. | Lapses during opposition Tooltip | AT | 04.02.2009 | BE | 04.02.2009 | DK | 04.02.2009 | FI | 04.02.2009 | SE | 04.05.2009 | GR | 05.05.2009 | PT | 06.07.2009 | [2014/38] |
Former [2011/25] | AT | 04.02.2009 | |
BE | 04.02.2009 | ||
DK | 04.02.2009 | ||
FI | 04.02.2009 | ||
SE | 04.05.2009 | ||
GR | 05.05.2009 | ||
PT | 06.07.2009 | ||
Former [2010/05] | AT | 04.02.2009 | |
BE | 04.02.2009 | ||
DK | 04.02.2009 | ||
FI | 04.02.2009 | ||
SE | 04.05.2009 | ||
PT | 06.07.2009 | Cited in | International search | [X]WO9321202 (YISSUM RES DEV CO [IL], et al) [X] 1-4,7,8,11 * see page 36, first paragraph *; | [A]WO9403596 (UNIV HAWAII [US]) [A] 5 * see pages 30-36 *; | [XA]WO9411494 (UNIV JEFFERSON [US], et al) [X] 1-4,7-11 * see page 5;page 11, second paragraph continued on page 12; pages 19-20; * [A] 12-20; | [XA]WO9422487 (UNIV JEFFERSON [US], et al) [X] 1-4,7,8 * see Example 2 * [A] 10,12-20; | [XA] - ROBINSON-BENION, C. ET AL., "Gene transplantation: Combined antisense inhibition and gene replacement strategies", LEUKEMIA, (199404), vol. 8, pages s152 - s155, XP000652853 [X] 1-4,7,8,11-15 * see p.152, right-hand column, l. 17-19; p.153, left-hand column, l. 1-4 and 18-21; Abstract * * see last sentence of the Abstract and Discussion * [A] 10,16-20 | [X] - CHANG, J.L.C. ET AL., "Antisense RNA complementary to 3'coding and noncoding sequences of creatine kinase is a potent inhibitor of translation in vivo", PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES, vol. 86, pages 10006 - 10010, XP000652039 [X] 1-4,7-9,11 * see page 10006, right-hand column, second and third paragraph * DOI: http://dx.doi.org/10.1073/pnas.86.24.10006 | [A] - POSTEL, E.H. ET AL., "Evidence that a triplex-forming oligodeoxyribonucleotide binds to the c-myc promoter in HeLa cells, thereby reducing c-myc RNA levels", PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES, (1991), vol. 88, pages 8227 - 8231, XP002028900 [A] 6 * see the whole document * | [A] - MARINI, J.C. AND WANG, C., "Antisense oligonucleotides selectively suppress production of mutant alpha2(I) collagen in osteogenesis imperfecta type IV fibroblasts: an approach to gene therapy for a dominant disorder of matrix structural protein", PEDIATRIC RESEARCH, (199504), vol. 37, no. 4, page 150, XP000652811 [A] 1 * see the whole Abstract * |