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Extract from the Register of European Patents

EP About this file: EP0851918

EP0851918 - STRATEGY FOR SUPPRESSING THE EXPRESSION OF AN ENDOGENEOUS GENE BY USING COMPOUNDS THAT ARE ABLE TO BIND TO THE NON-CODING REGIONS OF THE GENE TO BE SUPPRESSED [Right-click to bookmark this link]
StatusNo opposition filed within time limit
Status updated on  11.12.2009
Database last updated on 02.11.2024
Most recent event   Tooltip15.08.2014Lapse of the patent in a contracting statepublished on 17.09.2014  [2014/38]
Applicant(s)For all designated states
Optigen Patents Limited
The Smurfit Institute of Genetics Trinity College Dublin
Dublin 2 / IE
[2008/52]
Former [2005/05]For all designated states
Optigen Patents Limited
Department of Genetics Trinity College Dublin
Dublin 2 / IE
Former [1998/28]For all designated states
Provost, Fellows and Scholars of the College of the Holy and Undivided Trinity of Queen Elizabeth near Dublin
Trinity College
Dublin, Dublin 2 / IE
Inventor(s)01 / FARRAR, Gwenyth, Jane
9 The Crescent, Monkstown D20
County Dublin / IE
02 / HUMPHRIES, Peter
5 Holmwood, Cabinteely D15
County Dublin / IE
03 / KENNA, Paul, Francis
176 New Cabra Road
Dublin 7 / IE
[1998/28]
Representative(s)Main, Malcolm Charles, et al
Murgitroyd & Company
Scotland House
165-169 Scotland Street
Glasgow G5 8PL / GB
[N/P]
Former [2009/48]Main, Malcolm Charles, et al
Murgitroyd & Company Scotland House 165-169 Scotland Street
Glasgow G5 8PL / GB
Former [2006/18]Main, Malcolm Charles, et al
Murgitroyd & Company Scotland House 165-169 Scotland Street
Glasgow, G5 8PL / GB
Former [1998/28]Pattullo, Norman, et al
Murgitroyd and Company 373 Scotland Street
Glasgow G5 8QA / GB
Application number, filing date96931887.223.09.1996
[1998/28]
WO1996GB02357
Priority number, dateGB1995001929921.09.1995         Original published format: GB 9519299
[1998/28]
Filing languageEN
Procedural languageEN
PublicationType: A2 Application without search report
No.:WO9711169
Date:27.03.1997
Language:EN
[1997/14]
Type: A2 Application without search report 
No.:EP0851918
Date:08.07.1998
Language:EN
The application published by WIPO in one of the EPO official languages on 27.03.1997 takes the place of the publication of the European patent application.
[1998/28]
Type: B1 Patent specification 
No.:EP0851918
Date:04.02.2009
Language:EN
[2009/06]
Search report(s)International search report - published on:EP12.06.1997
ClassificationIPC:C12N15/11, C12N9/00, C12N15/85, A61K48/00
[1998/28]
CPC:
C12N15/113 (EP,US); C07K14/47 (EP,US); C07K14/78 (EP,US);
A61K38/00 (EP,US); A61K48/00 (EP,US); C12N2310/121 (EP,US);
C12N2310/15 (EP,US); C12N2310/3181 (EP,US) (-)
Designated contracting statesAT,   BE,   CH,   DE,   DK,   ES,   FI,   FR,   GB,   GR,   IE,   IT,   LI,   LU,   MC,   NL,   PT,   SE [1998/28]
TitleGerman:STRATEGIE ZUR UNTERDRUCKUNG DER EXPRESSION EINES ENDOGENEN GENES DURCH VERWENDUNG VON VERBINDUNGEN, DIE AN DIE NICHT-KODIERENDEN REGIONEN DES ZU HEMMENDEN GENES BINDEN KÖNNEN[1998/28]
English:STRATEGY FOR SUPPRESSING THE EXPRESSION OF AN ENDOGENEOUS GENE BY USING COMPOUNDS THAT ARE ABLE TO BIND TO THE NON-CODING REGIONS OF THE GENE TO BE SUPPRESSED[1998/28]
French:STRATEGIE PERMETTANT DE SUPPRIMER L'EXPRESSION D'UN GENE ENDOGENE EN UTILISANT DES COMPOSES CAPABLES DE SE LIER AUX REGIONS NON CODANTES D'UN GENE A SUPPRIMER[1998/28]
Entry into regional phase17.04.1998National basic fee paid 
17.04.1998Designation fee(s) paid 
17.04.1998Examination fee paid 
Examination procedure21.04.1997Request for preliminary examination filed
International Preliminary Examining Authority: EP
17.04.1998Examination requested  [1998/28]
24.09.2003Despatch of a communication from the examining division (Time limit: M08)
20.09.2004Reply to a communication from the examining division
02.05.2005Despatch of a communication from the examining division (Time limit: M06)
16.12.2005Despatch of communication that the application is deemed to be withdrawn, reason: reply to the communication from the examining division not received in time
23.02.2006Reply to a communication from the examining division
15.11.2007Despatch of a communication from the examining division (Time limit: M06)
19.05.2008Reply to a communication from the examining division
22.07.2008Communication of intention to grant the patent
20.11.2008Fee for grant paid
20.11.2008Fee for publishing/printing paid
Opposition(s)05.11.2009No opposition filed within time limit [2010/02]
Request for further processing for:23.02.2006Request for further processing filed
23.02.2006Full payment received (date of receipt of payment)
Request granted
13.03.2006Decision despatched
20.09.2004Request for further processing filed
20.09.2004Full payment received (date of receipt of payment)
Request granted
04.10.2004Decision despatched
Fees paidRenewal fee
25.09.1998Renewal fee patent year 03
26.08.1999Renewal fee patent year 04
13.09.2000Renewal fee patent year 05
12.09.2001Renewal fee patent year 06
12.09.2002Renewal fee patent year 07
12.09.2003Renewal fee patent year 08
23.08.2004Renewal fee patent year 09
05.09.2005Renewal fee patent year 10
08.09.2006Renewal fee patent year 11
05.09.2007Renewal fee patent year 12
05.09.2008Renewal fee patent year 13
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competence of the Unified
Patent Court
See the Register of the Unified Patent Court for opt-out data
Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court.
Lapses during opposition  TooltipAT04.02.2009
BE04.02.2009
DK04.02.2009
FI04.02.2009
SE04.05.2009
GR05.05.2009
PT06.07.2009
[2014/38]
Former [2011/25]AT04.02.2009
BE04.02.2009
DK04.02.2009
FI04.02.2009
SE04.05.2009
GR05.05.2009
PT06.07.2009
Former [2010/05]AT04.02.2009
BE04.02.2009
DK04.02.2009
FI04.02.2009
SE04.05.2009
PT06.07.2009
Cited inInternational search[X]WO9321202  (YISSUM RES DEV CO [IL], et al) [X] 1-4,7,8,11 * see page 36, first paragraph *;
 [A]WO9403596  (UNIV HAWAII [US]) [A] 5 * see pages 30-36 *;
 [XA]WO9411494  (UNIV JEFFERSON [US], et al) [X] 1-4,7-11 * see page 5;page 11, second paragraph continued on page 12; pages 19-20; * [A] 12-20;
 [XA]WO9422487  (UNIV JEFFERSON [US], et al) [X] 1-4,7,8 * see Example 2 * [A] 10,12-20;
 [XA]  - ROBINSON-BENION, C. ET AL., "Gene transplantation: Combined antisense inhibition and gene replacement strategies", LEUKEMIA, (199404), vol. 8, pages s152 - s155, XP000652853 [X] 1-4,7,8,11-15 * see p.152, right-hand column, l. 17-19; p.153, left-hand column, l. 1-4 and 18-21; Abstract * * see last sentence of the Abstract and Discussion * [A] 10,16-20
 [X]  - CHANG, J.L.C. ET AL., "Antisense RNA complementary to 3'coding and noncoding sequences of creatine kinase is a potent inhibitor of translation in vivo", PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES, vol. 86, pages 10006 - 10010, XP000652039 [X] 1-4,7-9,11 * see page 10006, right-hand column, second and third paragraph *

DOI:   http://dx.doi.org/10.1073/pnas.86.24.10006
 [A]  - POSTEL, E.H. ET AL., "Evidence that a triplex-forming oligodeoxyribonucleotide binds to the c-myc promoter in HeLa cells, thereby reducing c-myc RNA levels", PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES, (1991), vol. 88, pages 8227 - 8231, XP002028900 [A] 6 * see the whole document *
 [A]  - MARINI, J.C. AND WANG, C., "Antisense oligonucleotides selectively suppress production of mutant alpha2(I) collagen in osteogenesis imperfecta type IV fibroblasts: an approach to gene therapy for a dominant disorder of matrix structural protein", PEDIATRIC RESEARCH, (199504), vol. 37, no. 4, page 150, XP000652811 [A] 1 * see the whole Abstract *
The EPO accepts no responsibility for the accuracy of data originating from other authorities; in particular, it does not guarantee that it is complete, up to date or fit for specific purposes.