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EP0871647
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EP About this file: EP0871647
| EP0871647 - OLIGOMERS WHICH INHIBIT EXPRESSION OF COLLAGEN GENES [Right-click to bookmark this link] | Status | The application is deemed to be withdrawn Status updated on 18.03.2005 Database last updated on 30.03.2026 | Most recent event Tooltip | 18.03.2005 | Application deemed to be withdrawn | published on 04.05.2005 [2005/18] | Applicant(s) | For all designated states Guntaka, Ramareddy V. 2909 Eastpointe Drive Columbia, MO 65201 / US | [1998/43] | Inventor(s) | 01 /
GUNTAKA, Ramareddy, V. 2909 Eastpointe Drive Columbia, MO 65201 / US | 02 /
WEBER, Karl, Theodore 1307 Stonehaven Columbia, MO 65203 / US | 03 /
KOVACS, Attilla Apartment 25,6238 Southwood Avenue St. Louis, MO 63105 / US | 04 /
KANDALA, Jagannadhachari 3300 Bellemeade Columbia, MO 65203 / US | [1998/43] | Representative(s) | Uexküll & Stolberg Partnerschaft von Patent- und Rechtsanwälten mbB Beselerstrasse 4 22607 Hamburg / DE | [N/P] |
| Former [1998/43] | UEXKÜLL & STOLBERG Patentanwälte Beselerstrasse 4 22607 Hamburg / DE | Application number, filing date | 96933005.9 | 12.09.1996 | [1998/43] | WO1996US14640 | Priority number, date | US19950528836 | 15.09.1995 Original published format: US 528836 | US19960712357 | 11.09.1996 Original published format: US 712357 | [1998/43] | Filing language | EN | Procedural language | EN | Publication | Type: | A1 Application with search report | No.: | WO9710254 | Date: | 20.03.1997 | Language: | EN | [1997/13] | Type: | A1 Application with search report | No.: | EP0871647 | Date: | 21.10.1998 | Language: | EN | The application published by WIPO in one of the EPO official languages on 20.03.1997 takes the place of the publication of the European patent application. | [1998/43] | Search report(s) | International search report - published on: | US | 20.03.1997 | (Supplementary) European search report - dispatched on: | EP | 29.07.2004 | Classification | IPC: | C07H21/04, A61K48/00 | [1998/43] | CPC: |
C12N15/113 (EP,KR,US);
A61K38/14 (KR);
A61P1/00 (EP);
A61P1/16 (EP);
A61P11/00 (EP);
A61P17/00 (EP);
A61P17/02 (EP);
A61P9/00 (EP);
A61P9/10 (EP);
A61K38/00 (EP,US);
C12N2310/15 (EP,KR,US);
C12N2310/315 (EP,KR,US);
C12N2310/3181 (EP,KR,US)
(-)
| Designated contracting states | AT, BE, CH, DE, DK, ES, FI, FR, GB, GR, IE, IT, LI, LU, MC, NL, PT, SE [1998/43] | Title | German: | OLIGOMERE DIE DIE EXPRESSION VON COLLAGEN-GENEN VERHINDERN | [1998/43] | English: | OLIGOMERS WHICH INHIBIT EXPRESSION OF COLLAGEN GENES | [1998/43] | French: | OLIGOMERES INHIBANT L'EXPRESSION DES GENES DU COLLAGENE | [1998/43] | Entry into regional phase | 03.04.1998 | National basic fee paid | 03.04.1998 | Search fee paid | 03.04.1998 | Designation fee(s) paid | 03.04.1998 | Examination fee paid | Examination procedure | 29.03.1997 | Request for preliminary examination filed International Preliminary Examining Authority: US | 03.04.1998 | Examination requested [1998/43] | 14.10.2004 | Application deemed to be withdrawn, date of legal effect [2005/18] | 22.11.2004 | Despatch of communication that the application is deemed to be withdrawn, reason: reply to the communication from the examining division not received in time [2005/18] | Fees paid | Renewal fee | 26.11.1998 | Renewal fee patent year 03 | 14.01.2000 | Renewal fee patent year 04 | 15.09.2000 | Renewal fee patent year 05 | 18.09.2001 | Renewal fee patent year 06 | 18.09.2002 | Renewal fee patent year 07 | 12.09.2003 | Renewal fee patent year 08 | Penalty fee | Additional fee for renewal fee | 30.09.1998 | 03 M06 Fee paid on 26.11.1998 | 30.09.1999 | 04 M06 Fee paid on 14.01.2000 | 30.09.2004 | 09 M06 Not yet paid |
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| Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court. | Documents cited: | Search | [PX] KOVACS A. ET AL.: "Triple helix-forming oligonucleotide corresponding to the polypyrimidine sequence in the rat alpha1(I) collagen promoter specifically inhibits factor binding and transcription", THE JOURNAL OF BIOLOGICAL CHEMISTRY, vol. 271, no. 3, 19 January 1996 (1996-01-19), pages 1805 - 1812, XP002288333 DOI: http://dx.doi.org/10.1074/jbc.271.3.1805 | [A] KOVACS A. ET AL.: "Studies on the regulation of the alpha1(I) collagen gene expression: triple helix-forming oligonucleotide specifically inhibits the in vitro transcription of rat alpha1(I) collagen gene", CLINICAL RESEARCH, vol. 42, no. 3, 1994, pages 395A, XP008032786 [A] * the whole document * | [A] LICHTLER A. ET AL.: "Isolation and characterization of the rat alpha1(I) collagen promoter", THE JOURNAL OF BIOLOGICAL CHEMISTRY, vol. 264, no. 6, 25 February 1989 (1989-02-25), pages 3072 - 3077, XP002288335 [A] * page 417 - page 418 * | [A] LAPTEV A.V. ET AL.: "Specific inhibition of expression of human collagen gene (COLIA1) with modified antisense oligonucleotides. The most efective target site are clustered in double-stranded regions of the predicted secondary structure for the mRNA", BIOCHEMISTRY, vol. 33, no. 36, 1994, pages 11033 - 11039, XP002925082, ISSN: 0006-2960 [A] DOI: http://dx.doi.org/10.1021/bi00202a024 | [A] DATABASE MEDLINE [online] US NATIONAL LIBRARY OF MEDICINE (NLM), BETHESDA, MD, US; December 1992 (1992-12-01), KIYAMA R: "[Triplex DNA for therapeutics]", XP002288336, Database accession no. NLM1491462 [A] | [A] NIPPON RINSHO. JAPANESE JOURNAL OF CLINICAL MEDICINE. DEC 1992, vol. 50, no. 12, December 1992 (1992-12-01), pages 3117 - 3124, ISSN: 0047-1852 | [A] COONEY M. ET AL.: "Site-specific oligonucleotide binding represses transcription of the human c-myc gene in vitro", SCIENCE, vol. 241, 22 July 1988 (1988-07-22), pages 456 - 459, XP008032785 [A] DOI: http://dx.doi.org/10.1126/science.3293213 | [PX] KIM H.-G. AND MILLER D.M.: "Inhibition of in vitro transcription by a triplex-forming oligonucleotide targeted to human c-myc P2 promoter", BIOCHEMISTRY, vol. 34, no. 25, 27 June 1995 (1995-06-27), pages 8165 - 8171, XP002288339 [PX] 1-13 * the whole document * DOI: http://dx.doi.org/10.1021/bi00025a023 | International search | [Y] CHEMICAL REVIEWS, June 1990, Vol. 90, UHLMANN et al., "Antisense Oligonucleotides: a New Therapeutic Principle", pages 543-584. [Y] | [Y] PROC. NATL. ACAD. SCI. U.S.A., March 1984, Vol. 81, HARBERS et al., "Insertion of Retrovirus Into the First Intron of alpha1(I)Collagen Gene Leads to Embryonic Mutation in Mice", pages 1504-1508. [Y] | [Y] MAMMALIAN GENOME, 1995, Vol. 6, STAUBLI et al., "Structure and Chromosomal Localization of the Mouse Oncomodulin Gene", pages 769-777. [Y] |