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Extract from the Register of European Patents

EP About this file: EP0853681

EP0853681 - ARF-p19, A NOVEL REGULATOR OF THE MAMMALIAN CELL CYCLE [Right-click to bookmark this link]
StatusThe application is deemed to be withdrawn
Status updated on  13.08.2004
Database last updated on 16.11.2024
Most recent event   Tooltip13.08.2004Application deemed to be withdrawnpublished on 29.09.2004  [2004/40]
Applicant(s)For all designated states
ST. JUDE CHILDREN'S RESEARCH HOSPITAL
332 North Lauderdale
Memphis, TN 38105-2794 / US
[1998/30]
Inventor(s)01 / SHERR, Charles, J.
67 Grove Park Circle
Memphis, TN 38117 / US
02 / QUELLE, Dawn, E.
8579 Ericson Cove
Cordova, TN 38018 / US
[1998/30]
Representative(s)Chapman, Paul William, et al
Kilburn & Strode LLP
20 Red Lion Street
London
WC1R 4PJ / GB
[N/P]
Former [1998/30]Chapman, Paul William, et al
Kilburn & Strode, 20 Red Lion Street
London WC1R 4PJ / GB
Application number, filing date96933880.525.09.1996
[1998/30]
WO1996US15312
Priority number, dateUS1995053497527.09.1995         Original published format: US 534975
[1998/30]
Filing languageEN
Procedural languageEN
PublicationType: A1 Application with search report
No.:WO9712060
Date:03.04.1997
Language:EN
[1997/15]
Type: A1 Application with search report 
No.:EP0853681
Date:22.07.1998
Language:EN
The application published by WIPO in one of the EPO official languages on 03.04.1997 takes the place of the publication of the European patent application.
[1998/30]
Search report(s)International search report - published on:US03.04.1997
(Supplementary) European search report - dispatched on:EP12.07.2002
ClassificationIPC:C12Q1/68, G01N33/53, C12P21/06, C12N5/00, C12N15/00, C07K1/00, C07K16/00, C07H21/04
[1998/30]
CPC:
C07K14/4703 (EP,US); A61P35/00 (EP); A61P43/00 (EP);
A01K2217/05 (EP,US); A01K2217/075 (EP,US); A61K38/00 (EP,US);
C07K2319/00 (EP,US) (-)
Designated contracting statesAT,   BE,   CH,   DE,   DK,   ES,   FI,   FR,   GB,   GR,   IE,   IT,   LI,   LU,   MC,   NL,   PT,   SE [1998/30]
TitleGerman:ARF-P19, EIN NEUARTIGER REGULATORDES SÄUGETIERZELLZYKLUS[1998/30]
English:ARF-p19, A NOVEL REGULATOR OF THE MAMMALIAN CELL CYCLE[1998/30]
French:ARF-p19 NOUVEAU REGULATEUR DU CYCLE DE LA CELLULE MAMMIFERE[1998/30]
Entry into regional phase27.04.1998National basic fee paid 
27.04.1998Search fee paid 
27.04.1998Designation fee(s) paid 
27.04.1998Examination fee paid 
Examination procedure28.04.1997Request for preliminary examination filed
International Preliminary Examining Authority: US
27.04.1998Examination requested  [1998/30]
05.09.2003Despatch of a communication from the examining division (Time limit: M06)
16.03.2004Application deemed to be withdrawn, date of legal effect  [2004/40]
26.04.2004Despatch of communication that the application is deemed to be withdrawn, reason: reply to the communication from the examining division not received in time  [2004/40]
Fees paidRenewal fee
28.09.1998Renewal fee patent year 03
13.09.1999Renewal fee patent year 04
13.09.2000Renewal fee patent year 05
12.09.2001Renewal fee patent year 06
12.09.2002Renewal fee patent year 07
12.09.2003Renewal fee patent year 08
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Documents cited:Search[X]  - DURO ET AL., "Human p16INK4/MTS1 mRNA, complete cds", EMBL/GENBANK, (19950619), Database accession no. U26727, XP002203206 [X] 1-21,26-30 * alternative INK4a transcript which encodes protein with 100% identity to SEQ ID No 4 (human ARF-p19) *
International search[YP]WO9525249  (ALSBERG TERRY WAYNE [US]);
 [YP]WO9528483  (COLD SPRING HARBOR LAB [US])
 [Y]  - NATURE, 21 April 1994, Vol. 368, NOBORi et al., "Deletions of the Cyclin-Dependent Kinase-4 Inhibitor Gene in Multiple Human Cancers", pages 753-756.
 [Y]  - SCIENCE, 15 April 1994, Vol. 264, KAMB et al., "A Cell Cycle Regulator Potentially Involved in Genesis of Many Tumor Types", pages 436-440.
 [Y]  - ONCOGENE, 17 August 1995, Vol. 11, QUELLE et al., "Cloning and Characterization of Murine p16INK4a and p15INK4b Genes", pages 635-645.
 [XP]  - CELL, 15 December 1995, Vol. 83, QUELLE et al., "Alternative Reading Frames of the INK4a Tumor Suppressor Gene Encode Two Unrelated Proteins Capable of Inducing Cell Cycle Arrest", pages 993-1000.
 [Y]  - GENES & DEVELOPMENT, 1994, Vol. 8, GUAN et al., "Growth Suppression by p18, a p16INK4/MTS1- and p14INK4b/MTS2-Related CDK6 Inhibitor, Correlates with Wild-Type pRb Function", pages 2939-2952.
 [Y]  - PROC. NATL. ACAD. SCI. U.S.A., November 1994, Vol. 91, OKAMOTO et al., "Mutations and Altered Expression of p16INK4 in Human Cancer", pages 11045-11049.
 [X]  - ONCOGENE, 1995, Vol. 11, DURO et al., "A New Type of p16INK4/MTS1 Gene Transcript Expressed in B-Cell Malignancies", pages 21-29.
 [X]  - CANCER RESEARCH, 15 July 1995, Vol. 55, STONE et al., "Complex Structure and Regulation of the P16 (MTS1) Locus", pages 2988-2994.
The EPO accepts no responsibility for the accuracy of data originating from other authorities; in particular, it does not guarantee that it is complete, up to date or fit for specific purposes.