Extract from the Register of European Patents

EP About this file: EP0876361

EP0876361 - 4,10BETA-DIACETOXY-2ALPHA-BENZOYLOXY-5BETA,20-EPOXY-1-HYDROXY-9-OXO-19-NOR-CYCLOPROPA(G]TAX-11-ENE-13ALPHA-YL (2R,3S)-TERT-BUTOXYCARBONYLAMINO-2-HYDROXY-3-PHENYLPROPIONATE DIHYDRATE, AND METHOD FOR PREPARING SAME [Right-click to bookmark this link]
Former [1998/46]4,10$g(b)-DIACETOXY-2$g(a)-BENZOYLOXY-5$g(b),20-EPOXY-1-HYDROXY-9-OXO-19-NOR-CYCLOPROPA G]TAX-11-ENE-13$g(a)-YL (2R,3S)-TERT-BUTOXYCARBONYLAMINO-2-HYDROXY-3-PHENYLPROPIONATE DIHYDRATE, AND METHOD FOR PREPARING SAME
[1999/52]
StatusNo opposition filed within time limit
Status updated on  28.06.2002
Database last updated on 21.03.2026
Most recent event   Tooltip15.11.2013Lapse of the patent in a contracting statepublished on 18.12.2013  [2013/51]
Applicant(s)For all designated states
Aventis Pharma S.A.
20, avenue Raymond Aron
92160 Antony / FR
[2001/34]
Former [1998/46]For all designated states
RHONE-POULENC RORER S.A.
20, avenue Raymond Aron
92160 Antony / FR
Inventor(s)01 / DIDIER, Eric
24, Rue de la Glacière
F-75013 Paris / FR
02 / LAVIGNE, Michel
4, allée des Acacias
F-91380 Chilly-Mazarin / FR
03 / AUTHELIN, Jean-René
51, résidence les Cendrennes
F-91180 Saint-Germain-les-Arpajon / FR
[1999/01]
Former [1998/46]01 / DIDIER, Eric
69, avenue des Gobelins
F-75013 Paris / FR
02 / LAVIGNE, Michel
4, allée des Acacias
F-91380 Chilly-Mazarin / FR
03 / AUTHELIN, Jean-René
51, résidence les Cendrennes
F-91180 Saint-Germain-les-Arpajon / FR
Representative(s)Le Pennec, Magali, et al
Aventis Pharma S.A.
Direction des Brevets
Tri LEO/144
20 Avenue Raymond Aron
92165 Antony Cedex / FR
[N/P]
Former [1998/46]Le Pennec, Magali, et al
RHONE-POULENC RORER SA, Direction des Brevets, 20 Avenue Raymond Aron
92165 Antony Cédex / FR
Application number, filing date96941720.309.12.1996
[1998/46]
WO1996FR01957
Priority number, dateFR1995001484114.12.1995         Original published format: FR 9514841
[1998/46]
Filing languageFR
Procedural languageFR
PublicationType: A1 Application with search report
No.:WO9721695
Date:19.06.1997
Language:FR
[1997/26]
Type: A1 Application with search report 
No.:EP0876361
Date:11.11.1998
Language:FR
The application published by WIPO in one of the EPO official languages on 19.06.1997 takes the place of the publication of the European patent application.
[1998/46]
Type: B1 Patent specification 
No.:EP0876361
Date:22.08.2001
Language:FR
[2001/34]
Search report(s)International search report - published on:EP19.06.1997
ClassificationIPC:C07D305/14, A61K31/335
[1998/46]
CPC:
C07D305/14 (EP,KR); A61P35/00 (EP); A61P35/02 (EP)
Designated contracting statesAT,   BE,   CH,   DE,   DK,   ES,   FI,   FR,   GB,   GR,   IE,   IT,   LI,   LU,   NL,   PT,   SE [1998/46]
TitleGerman:DIHYDRAT VON (2R,3S)-3-TERT-BUTOXYCARBONYLAMINO-2-HYDROXY-3-PHENYLPROPIONSÄURE ESTER VON 4,10-BETA-DIACETOXY-2ALPHA-BENZOYLOXY-5BETA, 20-EPOXY-1-HYDROXY-9-OXO-19-NOR-CYCLOPROPA(G]TAX-11-EN-13ALPHA-YL UND VERFAHREN ZU IHRER HERSTELLUNG[1999/52]
English:4,10BETA-DIACETOXY-2ALPHA-BENZOYLOXY-5BETA,20-EPOXY-1-HYDROXY-9-OXO-19-NOR-CYCLOPROPA(G]TAX-11-ENE-13ALPHA-YL (2R,3S)-TERT-BUTOXYCARBONYLAMINO-2-HYDROXY-3-PHENYLPROPIONATE DIHYDRATE, AND METHOD FOR PREPARING SAME[1999/52]
French:DIHYDRATE DU (2R,3S)-3-TERT-BUTOXYCARBONYLAMINO-2-HYDROXY-3-PHENYLPROPIONATE DE 4,10BETA-DIACETOXY-2ALPHA-BENZOYLOXY-5BETA,20-EPOXY-1-HYDROXY-9-OXO-19-NOR-CYCLOPROPA G]TAX-11-ENE-13ALPHA-YLE, ET SON PROCEDE DE PREPARATION[1999/52]
Former [1998/46]DIHYDRAT VON (2R,3S)-3-TERT-BUTOXYCARBONYLAMINO-2-HYDROXY-3-PHENYLPROPIONSÄURE ESTER VON 4,10-BETA-DIACETOXY-2ALFA-BENZOYLOXY-5BETA, 20-EPOXY-1-HYDROXY-9-OXO-19-NOR-CYCLOPROPA G]TAX-11-EN-13ALFA-YL UND VERFAHREN ZU IHRER HERSTELLUNG
Former [1998/46]4,10$g(b)-DIACETOXY-2$g(a)-BENZOYLOXY-5$g(b),20-EPOXY-1-HYDROXY-9-OXO-19-NOR-CYCLOPROPA G]TAX-11-ENE-13$g(a)-YL (2R,3S)-TERT-BUTOXYCARBONYLAMINO-2-HYDROXY-3-PHENYLPROPIONATE DIHYDRATE, AND METHOD FOR PREPARING SAME
Former [1998/46]DIHYDRATE DU (2R,3S)-3-TERT-BUTOXYCARBONYLAMINO-2-HYDROXY-3-PHENYLPROPIONATE DE 4,10$g(b)-DIACETOXY-2$g(a)-BENZOYLOXY-5$g(b),20-EPOXY-1-HYDROXY-9-OXO-19-NOR-CYCLOPROPA G]TAX-11-ENE-13$g(a)-YLE, ET SON PROCEDE DE PREPARATION
Entry into regional phase08.06.1998National basic fee paid 
08.06.1998Designation fee(s) paid 
08.06.1998Examination fee paid 
Examination procedure05.06.1997Request for preliminary examination filed
International Preliminary Examining Authority: EP
08.06.1998Examination requested  [1998/46]
07.02.2001Despatch of communication of intention to grant (Approval: Yes)
26.02.2001Communication of intention to grant the patent
17.04.2001Fee for grant paid
17.04.2001Fee for publishing/printing paid
Opposition(s)23.05.2002No opposition filed within time limit [2002/33]
Fees paidRenewal fee
23.11.1998Renewal fee patent year 03
20.11.1999Renewal fee patent year 04
23.11.2000Renewal fee patent year 05
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Former [2003/01]GB09.12.2001
Cited inInternational search[A]   CHEMICAL ABSTRACTS, vol. 113, no. 75, 1990, Columbus, Ohio, US; abstract no. 142641k, GUERITTE-VOGELEIN ET AL.: "structure of a synthetic taxol precursor." page 723; column 2; XP002007111 [A] 1-5 * abstract *
 [A]   ACTA CRISTALLOGR. SECT. C:CRYSTAL STRUCTURE COMMUN., vol. C46, no. 5, 1990, ENGL., pages 781 - 784
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