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Extract from the Register of European Patents

EP About this file: EP0870041

EP0870041 - KVLQT1 - A LONG QT SYNDROME GENE WHICH ENCODES KVLQT1 WHICH COASSEMBLES WITH minK TO FORM CARDIAC Iks POTASSIUM CHANNELS [Right-click to bookmark this link]
Former [1998/42]KVLQT1 - A LONG QT SYNDROME GENE WHICH ENCODES KVLQT1 WHICH COASSEMBLES WITH minK TO FORM CARDIAC I Ks? POTASSIUM CHANNELS
[1999/52]
StatusNo opposition filed within time limit
Status updated on  30.11.2007
Database last updated on 03.10.2024
Most recent event   Tooltip02.05.2008Lapse of the patent in a contracting state
New state(s): IT		published on 04.06.2008  [2008/23]
Applicant(s)For all designated states
The University of Utah Research Foundation
615 Arapeen Drive, Suite 310
Salt Lake City, Utah 84108 / US
[N/P]
Former [2006/10]For all designated states
The University of Utah Research Foundation
615 Arapeen Drive, Suite 310 Salt Lake City
Utah 84108 / US
Former [1998/42]For all designated states
UNIVERSITY OF UTAH RESEARCH FOUNDATION
421 Wakara Way, Suite 170
Salt Lake City, Utah 84108 / US
Inventor(s)01 / KEATING, Mark, T.
78 Laurel Street
Salt Lake City, UT 84103 / US
02 / SANGUINETTI, Michael, C.
4922 East Meadows Drive
Park City, UT 84060 / US
03 / CURRAN, Mark, E.
227 Wood Street
Hopkinton, MA 01748 / US
 [2004/45]
Former [2004/14]01 / KEATING, Mark, T.
78 Laurel Street
Salt Lake City, UT 84103 / US
02 / SANGUINETTI, Michael, C.
4922 East Meadows Drive
Park City, UT 84060 / US
03 / CURRAN, Mark, E.
227 Wood Street
Hopkinton, MA 01748 / US
04 / WANG, Qing
3316 Daleford Road
Shaker Heights, Ohio 44120 / US
Former [1999/25]01 / KEATING, Mark, T.
78 Laurel Street
Salt Lake City, UT 84103 / US
02 / SANGUINETTI, Michael, C.
4922 East Meadows Drive
Park City, UT 84060 / US
03 / CURRAN, Mark, E.
227 Wood Street
Hopkinton, MA 01748 / US
Former [1998/42]01 / KEATING, Mark, T.
78 Laurel Street
Salt Lake City, UT 84103 / US
02 / SANGUINETTI, Michael, C.
4922 East Meadows Drive
Park City, UT 84060 / US
03 / CURRAN, Mark, E.
1032 E. 400 South 610B
Salt Lake City, UT 84102 / US
Representative(s)Dörries, Hans Ulrich, et al
df-mp Dörries Frank-Molnia & Pohlman
Patentanwälte Rechtsanwälte PartG mbB
Theatinerstrasse 16
80333 München / DE
[N/P]
Former [2005/01]Dörries, Hans Ulrich, Dr., et al
Dörries, Frank-Molnia & Pohlman, Triftstrasse 13
80538 München / DE
Former [2004/45]Wright, Simon Mark, et al
J.A. Kemp & Co. 14 South Square Gray's Inn
London WC1R 5JJ / GB
Former [2004/16]Irvine, Jonquil Claire, et al
J.A. KEMP & CO. 14 South Square Gray's Inn
London WC1R 5JJ / GB
Former [1998/42]Goldin, Douglas Michael, et al
J.A. KEMP & CO. 14 South Square Gray's Inn
London WC1R 5LX / GB
Application number, filing date96945935.320.12.1996
[1998/42]
WO1996US19756
Priority number, dateUS19950019014P22.12.1995         Original published format: US 19014 P
US1996073938329.10.1996         Original published format: US 739383
[1998/42]
Filing languageEN
Procedural languageEN
PublicationType: A2 Application without search report
No.:WO9723598
Date:03.07.1997
Language:EN
[1997/29]
Type: A2 Application without search report 
No.:EP0870041
Date:14.10.1998
Language:EN
The application published by WIPO in one of the EPO official languages on 03.07.1997 takes the place of the publication of the European patent application.
[1998/42]
Type: B1 Patent specification 
No.:EP0870041
Date:24.01.2007
Language:EN
[2007/04]
Search report(s)International search report - published on:US12.09.1997
(Supplementary) European search report - dispatched on:EP06.12.2001
ClassificationIPC:C12N15/63, C12N5/00, C12N15/00, A01N43/04, A61K31/70
[2002/04]
CPC:
C07K14/47 (EP); C07K14/705 (EP); A01K2217/05 (EP);
A61K48/00 (EP)
Former IPC [1998/42]C12N15/63, C12N5/00, C12N15/00
Designated contracting statesAT,   BE,   CH,   DE,   DK,   ES,   FI,   FR,   GB,   GR,   IE,   IT,   LI,   LU,   MC,   NL,   PT,   SE [1998/42]
TitleGerman:KVLQT1 - EIN GEN DES LONG-QT-SYNDROMS, WELCHES FÜR KVLQT1 KODIERT UND WELCHES SICH MIT Mink ZUSAMMENSETZT, UM Iks-KALIUMKANÄLE DES HERZENS ZU BILDEN[1999/52]
English:KVLQT1 - A LONG QT SYNDROME GENE WHICH ENCODES KVLQT1 WHICH COASSEMBLES WITH minK TO FORM CARDIAC Iks POTASSIUM CHANNELS[1999/52]
French:KVLQT1- GENE DU SYNDROME DU QT LONG CODANT POUR KVLQT1, QUI SE COASSEMBLE AVEC minK POUR FORMER DES CANAUX POTASSIQUES CARDIAQUES Iks[1999/52]
Former [1998/42]KVLQT1 - EIN GEN DES LONG-QT-SYNDROMS, WELCHES FÜR KVLQT1 KODIERT UND WELCHES SICH MIT MINK ZUSAMMENSETZT, UM I-Ks?-KALIUMKANÄLE DES HERZENS ZU BILDEN
Former [1998/42]KVLQT1 - A LONG QT SYNDROME GENE WHICH ENCODES KVLQT1 WHICH COASSEMBLES WITH minK TO FORM CARDIAC I Ks? POTASSIUM CHANNELS
Former [1998/42]KVLQT1- GENE DU SYNDROME DU QT LONG CODANT POUR KVLQT1, QUI SE COASSEMBLE AVEC minK POUR FORMER DES CANAUX POTASSIQUES CARDIAQUES I Ks?
Entry into regional phase23.06.1998National basic fee paid 
23.06.1998Search fee paid 
23.06.1998Designation fee(s) paid 
23.06.1998Examination fee paid 
Examination procedure18.07.1997Request for preliminary examination filed
International Preliminary Examining Authority: US
23.06.1998Examination requested  [1998/42]
17.11.2003Despatch of a communication from the examining division (Time limit: M06)
25.05.2004Reply to a communication from the examining division
29.09.2005Despatch of a communication from the examining division (Time limit: M04)
24.01.2006Reply to a communication from the examining division
18.08.2006Communication of intention to grant the patent
28.11.2006Fee for grant paid
28.11.2006Fee for publishing/printing paid
Opposition(s)25.10.2007No opposition filed within time limit [2008/01]
Fees paidRenewal fee
04.12.1998Renewal fee patent year 03
06.12.1999Renewal fee patent year 04
07.12.2000Renewal fee patent year 05
31.12.2001Renewal fee patent year 06
23.12.2002Renewal fee patent year 07
29.12.2003Renewal fee patent year 08
23.12.2004Renewal fee patent year 09
27.12.2005Renewal fee patent year 10
13.12.2006Renewal fee patent year 11
Opt-out from the exclusive  Tooltip
competence of the Unified
Patent Court		 See the Register of the Unified Patent Court for opt-out data
Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court.
Lapses during opposition  TooltipAT24.01.2007
BE24.01.2007
CH24.01.2007
DK24.01.2007
FI24.01.2007
IT24.01.2007
LI24.01.2007
NL24.01.2007
SE24.04.2007
GR25.04.2007
ES05.05.2007
PT25.06.2007
[2008/23]
Former [2008/21]AT24.01.2007
BE24.01.2007
CH24.01.2007
DK24.01.2007
FI24.01.2007
LI24.01.2007
NL24.01.2007
SE24.04.2007
GR25.04.2007
ES05.05.2007
PT25.06.2007
Former [2008/07]AT24.01.2007
BE24.01.2007
CH24.01.2007
DK24.01.2007
FI24.01.2007
LI24.01.2007
NL24.01.2007
SE24.04.2007
ES05.05.2007
PT25.06.2007
Documents cited:Search[XP]  - BARHANIN J ET AL, "KVLQT1 AND ISK (MINK) PROTEINS ASSOCIATE TO FORM TH IKS CARDIAC POTASSIUM CURRENT", NATURE, MACMILLAN JOURNALS LTD. LONDON, GB, (19961107), vol. 384, ISSN 0028-0836, pages 78 - 80, XP002910425 [XP] 1-20 * the whole document *

DOI:   http://dx.doi.org/10.1038/384078a0
International search[YE]US5599673  (KEATING MARK T [US], et al);
 [XP]  - SANGUINETTI M C, ET AL., "COASSEMBLY OF KVLQT1 AND MINK (ISK) PROTEINS TO FORM CARDIAC I POTASSIUM CHANNEL", NATURE, Nature Publishing Group, United Kingdom, United Kingdom, (19961107), vol. 384, doi:10.1038/384080a0, ISSN 0028-0836, pages 80 - 83, XP002916128

DOI:   http://dx.doi.org/10.1038/384080a0
 [X]  - RUKNUDIN A M, ET AL., "CHARACTERIZATION OF A HUMAN MINK CHANNEL EXPRESSE IN XENOPUS OOCYTES", SOCIETY FOR NEUROSCIENCE, WASHINGTON, DC., (19930101), XP001022126
 [X]  - WANG Q, ET AL., "POSITIONAL CLONING OF A NOVEL POTASSIUM CHANNEL GENE:KVLQT1 MUTATIONS CAUSE CARDIAC ARRHYTHMIAS", NATURE GENETICS., Nature Publishing Group, NEW YORK, US, NEW YORK, US, (19960112), vol. 12, no. 01, doi:10.1038/ng0196-17, ISSN 1061-4036, pages 17 - 23, XP002916129

DOI:   http://dx.doi.org/10.1038/ng0196-17
 [YP]  - ATTALI B, "A NEW WAVE FOR HEART RHYTHMS", NATURE, Nature Publishing Group, United Kingdom, United Kingdom, (19961107), vol. 384, doi:10.1038/384024a0, ISSN 0028-0836, page 24/25, XP002916130

DOI:   http://dx.doi.org/10.1038/384024a0
 [Y]  - Lai, L.-P. Deng, C.-L. Moss, A.J. Kass, R.S. Liang, C.-s., "Polymorphism of the gene encoding a human minimal potassium ion channel (minK)", GENE., ELSEVIER, AMSTERDAM., NL, NL, (19941230), vol. 151, no. 1, doi:10.1016/0378-1119(94)90685-8, ISSN 0378-1119, pages 339 - 340, XP004042666

DOI:   http://dx.doi.org/10.1016/0378-1119(94)90685-8
 [YP]  - TANG M D, KACZMAREL L K, "Identification of a Novel KvLQT1-Like Gene (KL1)", ABSTRACTS OF THE SOCIETY FOR NEUROSCIENCE, SOCIETY FOR NEUROSCIENCE, WASHINGTON, DC., US, US, (19961101), vol. 22, no. 496.2, ISSN 0190-5295, page 1245, XP002965603
 [YP]  - RODEN D M, ET AL., "MULTIPLE MECHANISMS IN THE LONG-QT SYNDROME CURRENT KNOWLEDGE, GAPS, AND FUTURE DIRECTIONS", Circulation, Lippincott Williams & Wilkins, US, US, (19961015), vol. 94, no. 08, ISSN 0009-7322, pages 1996 - 2012, XP009007234
 [YP]  - PRIORI S. G., CANTU F., SCHWARTZ P. J., "THE LONG QT SYNDROME: NEW DIAGNOSTIC AND THERAPEUTIC APPROACH IN THE ERA OF MOLECULAR BIOLOGY.", Schweizerische Medizinische Wochenschrift, E M H Schweizerischer Aerzteverlag AG, CH, CH, (19960101), vol. 126., no. 41., ISSN 0036-7672, pages 1727 - 1731., XP000865562
 [YP]  - CIRCULATION, 10 November 1996, Vol. 94, No. 8, CHOY et al., "Regional Expression of HERG and KVLQT1 in Heart Failure", Abstract 0952, page I164., XP002965638
 [AP]  - PRIORI S-G, NAPOLITANO C, SCHWARTZ P-J, "A Molecular Basis For the Therapy of the Long QT Syndro me", ARCHIVES DES MALADIES DU COEUR ET DES VAISSEAUX., J.B. BALLIERE, PARIS., FR, FR, (19960901), vol. 89, no. 9, ISSN 0003-9683, pages 1185 - 1187, XP002965650
 [AP]  - LI HUA, ET AL., "Chromosome 11-Linke d Long QT Syndrome (LQT1) is the Most Common Form of Long QT Syndrome", PEDIATRICS, AMERICAN ACADEMY OF PEDIATRICS, EVANSTON, IL,, US, US, (19961025), vol. 98, no. 3, ISSN 0031-4005, pages 534 - 535, XP002965651
The EPO accepts no responsibility for the accuracy of data originating from other authorities; in particular, it does not guarantee that it is complete, up to date or fit for specific purposes.