EP0811682 - Method of producing L-lysine [Right-click to bookmark this link] | Status | Patent maintained as amended Status updated on 20.03.2017 Database last updated on 31.08.2024 | Most recent event Tooltip | 20.03.2017 | Change - inventor | 20.03.2017 | Patent maintained (B2 publication) | published on 19.04.2017 [2017/16] | Applicant(s) | For all designated states Ajinomoto Co., Inc. 15-1, Kyobashi 1-chome, Chuo-ku Tokyo 104-8315 / JP | [2017/14] |
Former [1997/50] | For all designated states Ajinomoto Co., Inc. No. 15-1, Kyobashi 1-chome, Chuo-ku Tokyo 104 / JP | Inventor(s) | 01 /
Hirano, Seiko, @c/o Ajinomoto Co., Inc. 1-1, Suzuki-cho Kawasaki-ku Kawasaki-shi, Kanagawa 210-8681 / JP | 02 /
Sugimoto, Masakazu, @c/o Ajinomoto Co., Inc. 1-1, Suzuki-cho Kawasaki-ku Kawasaki-shi, Kanagawa 210-8681 / JP | 03 /
Nakano, Eiichi, @c/o Ajinomoto Co., Inc. 1-1, Suzuki-cho Kawasaki-ku Kawasaki-shi, Kanagawa 210-8681 / JP | 04 /
Izui, Masako, @c/o Ajinomoto Co., Inc. 1-1, Suzuki-cho Kawasaki-ku Kawasaki-shi, Kanagawa 210-8681 / JP | 05 /
Hayakawa, Atsushi, @c/o Ajinomoto Co., Inc. 1-1 Suzuki-cho Kawasaki-ku Kawasaki-shi, Kanagawa 210-8681 / JP | 06 /
Yoshihara, Yasuhiko, @c/o Ajinomoto Co., Inc. 1-1, Suzuki-cho Kawasaki-ku Kawasaki-shi, Kanagawa 210-8681 / JP | 07 /
Nakamatsu, Tsuyoshi, @c/o Ajinomoto Co., Inc. 1-1, Suzuki-cho Kawasaki-ku Kawasaki-shi, Kanagawa 210-8681 / JP | [2017/16] |
Former [1998/40] | 01 /
Hirano, Seiko, Ajinomoto Co., Inc. Techn. & Eng. Lab.. 1-1 Suzuki-cho, Kawasaki-ku Kawasaki-shi, Kanagawa 210 / JP | ||
02 /
Sugimoto, Masakazu, Ajinomoto Co., Inc. Techn. & Eng. Lab.. 1-1 Suzuki-cho, Kawasaki-ku Kawasaki-shi, Kanagawa 210 / JP | |||
03 /
Nakano, Eiichi, Ajinomoto Co., Inc. Techn. & Eng. Lab.. 1-1 Suzuki-cho, Kawasaki-ku Kawasaki-shi, Kanagawa 210 / JP | |||
04 /
Izui, Masako, Ajinomoto Co., Inc. Techn. & Eng. Lab.. 1-1 Suzuki-cho, Kawasaki-ku Kawasaki-shi, Kanagawa 210 / JP | |||
05 /
Hayakawa, Atsushi, Ajinomoto Co., Inc. Techn. & Eng. Lab.. 1-1 Suzuki-cho, Kawasaki-ku Kawasaki-shi, Kanagawa 210 / JP | |||
06 /
Yoshihara, Yasuhiko, Ajinomoto Co., Inc. Techn. & Eng. Lab.. 1-1 Suzuki-cho, Kawasaki-ku Kawasaki-shi, Kanagawa 210 / JP | |||
07 /
Nakamatsu, Tsuyoshi, Ajinomoto Co., Inc. Techn. & Eng. Lab.. 1-1 Suzuki-cho, Kawasaki-ku Kawasaki-shi, Kanagawa 210 / JP | |||
Former [1997/50] | 01 /
Hirano, Seiko, Ajinomot Co., Inc. Techn. & Eng. LAb.. 1-1 Suzuki-cho, Kawasaki-ku Kawasaki-shi, Kanagawa 210 / JP | ||
02 /
Sugimoto, Masakazu, Ajinomoto Co., Inc. Techn. & Eng. LAb.. 1-1 Suzuki-cho, Kawasaki-ku Kawasaki-shi, Kanagawa 210 / JP | |||
03 /
Nakano, Eiichi, Ajinomoto Co., Inc. Techn. & Eng. LAb.. 1-1 Suzuki-cho, Kawasaki-ku Kawasaki-shi, Kanagawa 210 / JP | |||
04 /
Izui, Masako, Ajinomoto Co., Inc. Techn. & Eng. LAb.. 1-1 Suzuki-cho, Kawasaki-ku Kawasaki-shi, Kanagawa 210 / JP | |||
05 /
Hayakawa, Atsushi, Ajinomoto Co., Inc. Techn. & Eng. LAb.. 1-1 Suzuki-cho, Kawasaki-ku Kawasaki-shi, Kanagawa 210 / JP | |||
06 /
Yoshihara, Yasuhiko, Ajinomoto Co., Inc. Techn. & Eng. LAb.. 1-1 Suzuki-cho, Kawasaki-ku Kawasaki-shi, Kanagawa 210 / JP | |||
07 /
Nakamatsu, Tsuyoshi, Ajinomoto Co., Inc. Techn. & Eng. LAb.. 1-1 Suzuki-cho, Kawasaki-ku Kawasaki-shi, Kanagawa 210 / JP | Representative(s) | Hoffmann Eitle Patent- und Rechtsanwälte PartmbB Arabellastraße 30 81925 München / DE | [2017/16] |
Former [2012/24] | HOFFMANN EITLE Patent- und Rechtsanwälte Arabellastraße 4 81925 München / DE | ||
Former [2003/37] | Polz, Leo, Dr., et al Hoffmann Eitle Postfach 81 04 20 81904 München / DE | ||
Former [1997/50] | Kolb, Helga, Dr. Dipl.-Chem., et al Hoffmann Eitle, Patent- und Rechtsanwälte, Arabellastrasse 4 81925 München / DE | Application number, filing date | 97108764.8 | 02.06.1997 | [1997/50] | Priority number, date | JP19960142812 | 05.06.1996 Original published format: JP 14281296 | [1997/50] | Filing language | EN | Procedural language | EN | Publication | Type: | A2 Application without search report | No.: | EP0811682 | Date: | 10.12.1997 | Language: | EN | [1997/50] | Type: | A3 Search report | No.: | EP0811682 | Date: | 10.06.1998 | [1998/24] | Type: | B1 Patent specification | No.: | EP0811682 | Date: | 21.01.2004 | Language: | EN | [2004/04] | Type: | B2 New European patent specification | No.: | EP0811682 | Date: | 19.04.2017 | Language: | EN | [2017/16] | Search report(s) | (Supplementary) European search report - dispatched on: | EP | 28.04.1998 | Classification | IPC: | C12N9/06, C12N9/88, C12N15/77, C12P13/08 | [1997/50] | CPC data not yet available | Designated contracting states | DE, DK, ES, FR, GB, IT, NL [2017/16] |
Former [1997/50] | DE, DK, ES, FR, GB, IT, NL | Title | German: | Verfahren zur Herstellung von L-Lysin | [1997/50] | English: | Method of producing L-lysine | [1997/50] | French: | Procédé pour préparer L-lysine | [2003/33] |
Former [1997/50] | Prcédé pour preparér L-lysine | Biological material | This application mentions deposited biological material, check the file for details | Examination procedure | 15.07.1998 | Amendment by applicant (claims and/or description) | 02.09.1998 | Examination requested [1998/44] | 05.03.2002 | Despatch of a communication from the examining division (Time limit: M04) | 05.07.2002 | Reply to a communication from the examining division | 02.10.2002 | Despatch of a communication from the examining division (Time limit: M04) | 10.02.2003 | Reply to a communication from the examining division | 17.07.2003 | Communication of intention to grant the patent | 22.10.2003 | Fee for grant paid | 22.10.2003 | Fee for publishing/printing paid | 16.06.2007 | Observations by third parties | Opposition(s) | Opponent(s) | 01
21.10.2004
14.12.2004
ADMISSIBLE BASF Aktiengesellschaft -Patentabteilung - C6- Carl-Bosch-Strasse 38 D-67056 Ludwigshafen / DE Opponent's representative Bühler, Dirk Maiwald GmbH Elisenhof Elisenstraße 3 80335 München / DE | [N/P] |
Former [2008/31] | |||
Opponent(s) | 01
21.10.2004
14.12.2004
ADMISSIBLE BASF Aktiengesellschaft -Patentabteilung - C6- Carl-Bosch-Strasse 38 D-67056 Ludwigshafen / DE Opponent's representative Bühler, Dirk Maiwald Patentanwalts GmbH Elisenhof Eliesenstraße 3 80335 München / DE | ||
Former [2007/28] | |||
Opponent(s) | 01
21.10.2004
14.12.2004
ADMISSIBLE BASF Aktiengesellschaft Patente, Marken und Lizenzen 67056 Ludwigshafen / DE Opponent's representative Bühler, Dirk Maiwald Patentanwalts GmbH Elisenhof Eliesenstraße 3 80335 München / DE | ||
Former [2006/35] | |||
Opponent(s) | 01
21.10.2004
14.12.2004
ADMISSIBLE Bühler, Dirk Maiwald Patentanwalts GmbH Elisenhof Eliesenstraße 3 D-80335 München / DE | ||
Former [2004/51] | |||
Opponent(s) | 01
21.10.2004
BASF Aktiengesellschaft Patente, Marken und Lizenzen D-67056 Ludwigshafen / DE | 21.12.2004 | Invitation to proprietor to file observations on the notice of opposition | 02.05.2005 | Reply of patent proprietor to notice(s) of opposition | 22.08.2006 | Date of oral proceedings | 05.09.2006 | Despatch of a communication from the opposition division (Time limit: M02) | 05.09.2006 | Despatch of minutes of oral proceedings | 13.11.2006 | Reply to a communication from the opposition division | 11.12.2006 | Despatch of interlocutory decision in opposition | 20.11.2008 | Legal effect of interlocutory decision in opposition | 09.12.2016 | Despatch of communication that the patent will be maintained as amended | 13.02.2017 | Fee for printing new specification paid | Appeal following opposition | 21.02.2007 | Appeal received No. T0390/07 | 23.04.2007 | Statement of grounds filed | 21.02.2007 | Appeal received No. T0390/07 | 20.04.2007 | Statement of grounds filed | 20.11.2008 | Result of appeal procedure: appeal of the proprietor was rejected | 20.11.2008 | Date of oral proceedings | 27.11.2008 | Minutes of the oral proceedings despatched | Fees paid | Renewal fee | 14.06.1999 | Renewal fee patent year 03 | 13.06.2000 | Renewal fee patent year 04 | 13.06.2001 | Renewal fee patent year 05 | 12.06.2002 | Renewal fee patent year 06 | 12.06.2003 | Renewal fee patent year 07 |
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Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court. | Documents cited: | Search | [A]JPH05284970 ; | [A]JPH0775579 ; | [A]JPS61289887 ; | [Y]US4861722 (SANO KONOSUKE [JP], et al) [Y] 1-7 * column W *; | [A]EP0435132 (FORSCHUNGSZENTRUM JUELICH GMBH [DE]) [A] 1 * the whole document *; | [Y]WO9516042 (AJINOMOTO KK [JP], et al) [Y] 1-7 * abstract *; | [A]US5426052 (FLICKINGER MICHAEL C [US], et al) [A] 1,3-7 * column W *; | EP0733710 [ ] (AJINOMOTO KK [JP]) [ ] * page 4, line 11 - line 19 * * page 23, line 40 - page 34, line 38 *; | [PX]WO9640934 (AJINOMOTO KK [JP], et al) [PX] 1-7 * abstract * * page 54 - page 60 ** page 66 - page 68 * | [A] - PATENT ABSTRACTS OF JAPAN, (19940207), vol. 018, no. 071, Database accession no. (C - 1162), & JP05284970 A 19931102 (MITSUBISHI PETROCHEM CO LTD) [A] 1-7 * abstract * | [A] - PATENT ABSTRACTS OF JAPAN, (19950731), vol. 095, no. 006, & JP07075579 A 19950320 (MITSUBISHI CHEM CORP) [A] 1,2,4-7 * abstract * | [A] - PATENT ABSTRACTS OF JAPAN, (19870522), vol. 011, no. 159, Database accession no. (C - 423), & JP61289887 A 19861219 (KYOWA HAKKO KOGYO CO LTD) [A] 1,3 * abstract * | other | EP0699759 | EP1172437 | - CREMER J. ET AL., "CONTROL OF THE LYSINE BIOSYNTHESIS SEQUENCE IN CORYNEBACTERIUM GLUTAMICUM AS ANALYZED BY OVEREXPRESSION OF THE INDIVIDUAL CORRESPONDING GENES", APPLIED AND ENVIRONMENTAL MICROBIOLOGY, (199106), vol. 57, no. 6, pages 1746 - 1752, XP000616281 | - CREMER J. ET AL, "REGULATION OF ENZYMES OF LYSINE BIOSYNTHESIS IN CORYNEBACTERIUM GLUTAMICUM", JOURNAL OF GENERAL MICROBIOLOGY, (1988), vol. 134, no. 12, pages 3221 - 3229, XP008047559 | - JETTEN M S M; SINSKEY A J, "RECENT ADVANCES IN THE PHYSIOLOGY AND GENETICS OF AMINO ACID-PRODUCING BACTERIA", CRC CRITICAL REVIEWS IN BIOTECHNOLOGY, (1995), vol. 15, no. 1, pages 73 - 103, XP000613291 | Opposition | JPH01215280 | IE912791 | WO9203546 | FR2667875 | EP0584375 | EP0629699 | US5380657 | JPH07140614 | US5616480 | US5643790 | EP0841395 | EP1172437 | EP0699759 | WO2005059144 | - CREMER J. ET AL, "Control of the Lysine Biosynthesis Sequence in Corynebacterium glutamicum as Analyzed by Overexpression of the Individual Corresponding Genes", APPLIED AND ENVIRONMENTAL MICROBIOLOGY, (199106), vol. 57, no. 6, pages 1746 - 1752, XP000616281 | - SHAW-REID C.A. ET AL, "Flux through the tetrahydrodipicolinate succinylase pathway is dispensable for L-lysine production in Corynebacterium glutamicum", APPL. MICROBIOL BIOTECHNOL, (1999), vol. 51, doi:doi:10.1007/s002530051398, pages 325 - 333, XP000884352 DOI: http://dx.doi.org/10.1007/s002530051398 | - LABARRE J. ET AL, "Gene Replacement, Integration, and Amplification at the gdhA Locus of Corynebacterium glutamicum", JOURNAL OF BACTERIOLOGY, (199302), pages 1001 - 1007, XP008015643 | - the abstract of JP 03-147791 | - the abstract of JP 03-147792 | - CREMER J. ET AL, "Regulation of Enzymes of Lysine Biosynthesis in Corynebacterium glutamicum", JOURNAL OF GENERAL MICROBIOLOGY, (1988), vol. 134, pages 3221 - 3229, XP008047559 | - SHAW-REID C.A. ET AL, "Flux through the tetrahydrodipicolinate succinylase pathway is dispensable for L-lysine production in Corynebacterium glutamicum", APPL. MICROBIOL. BIOTECHNOL., (1995), vol. 51, doi:doi:10.1007/s002530051398, pages 325 - 333, XP000884352 DOI: http://dx.doi.org/10.1007/s002530051398 | - GLICK B.R. ET AL, Molecular Biotechnology, WASHINGTON, ASM PRESS, (1998), vol. 2, pages 115 - 116 | - STRAGIER P. ET AL, "Regulation of Diaminopimelate Decarboxylase Synthesis in Escherichia coli", J. MOL. BIOL., (1983), vol. 168, pages 321 - 331 | - KIEL J.A.K.W. ET AL, "A General Method for the Consecutive Integration of Single Copies of a Heterologous Gene at Multiple Locations in the Bacillus subtilis Chromosome by Replacement Recombination", APPLIED AND ENVIRONMENTAL MICROBIOLOGY, (199512), vol. 61, no. 12, pages 4244 - 4250, XP002365733 | - LI S.-J. ET AL, "Growth Rate Regulation of Escherichia coli Acetyl Coenzyme A Carboxylase, Which Catalyzes the First Committed Step of Lipid Biosynthesis", JOURNAL OF BACTERIOLOGY, (199301), vol. 175, no. 2, pages 332 - 340, XP000608157 | - PATEK M. ET AL, "Promoters from Corynebacterium glutamicum: cloning, molecular analysis and search for a consensus motif", MICROBIOLOGY, (1996), vol. 142, pages 1297 - 1309 | - EIKMANNS B.J. ET AL, "A family of Corynebacterium glutamicum / Escherichia coli shuttle vectors for cloning, controlled gene expression, and promotor probing", GENE, (1991), vol. 102, pages 93 - 98 | - ZUPANCIC T.J. ET AL, "Isolation of promoters from Brevibacterium flavum strain MJ233C and comparison of their gene expression levels in B. flavum and Escherichia coli", FEMES MICROBIOLOGY LETTERS, (1995), vol. 131, pages 121 - 126 | - SCHÄFER A. ET AL, "Small mobilizable multi-purpose cloning vectors derived from the Escherichia coli plasmids pK18 and pK19: selection of defined deletions in the chromosome of Corynebacterium glutamicum", GENE, (1994), vol. 145, doi:doi:10.1016/0378-1119(94)90324-7, pages 69 - 73, XP023540831 DOI: http://dx.doi.org/10.1016/0378-1119(94)90324-7 | - KRAFT A.E. ET AL, "Transcription analysis and nucleotide sequence of tox promoter / operator mutants of corynebacteriophage ß", MICROBIAL PATHOGENESIS, (1992), vol. 13, doi:doi:10.1016/0882-4010(92)90069-Z, pages 85 - 92, XP023312930 DOI: http://dx.doi.org/10.1016/0882-4010(92)90069-Z | - MISONO H. ET AL, "Properties of meso-x, Diaminopimelate D-Dehydrogenase from Bacillus sphaericus*", THE JOURNAL OF BIOLOGICAL CHEMISTRY, (1990), vol. 265, pages 10599 - 10605 | - ALBERTS B. ET AL, Molecular Biology of the Cell, NEW YORK - LONDON, GARLAND PUBLISHING, INC., (1994), vol. 3, pages 224 - 226 | - JETTEN M.S.M. ET AL, "Recent Advances in the Physiology and Genetics of Amino Acid-Producing Bacteria", CRITICAL REVIEWS IN BIOTECHNOLOGY, (1995), vol. 15, no. 1, pages 73 - 103, XP000613291 | - PATEK M. ET AL, "Promoters of Corynebacterium glutamicum", JOURNAL OF BIOTECHNOLOGY, (2003), vol. 104, doi:doi:10.1016/S0168-1656(03)00155-X, pages 311 - 323, XP002323247 DOI: http://dx.doi.org/10.1016/S0168-1656(03)00155-X | - SAKAMOTO S. ET AL, "Cloning, sequencing, and expression of the meso-diaminopimelate dehydrogenase gene from Bacillus sphaericus", JOURNAL OF MOLECULAR CATALYSIS B: ENZYMATIC, (2001), vol. 12, pages 85 - 92 | - BIOTECHNOLOGY ENCCLOPEDIA, CMC CO. LTD., (19861009), pages 810 - 811 | - MENKEL E. ET AL, "Influence of increased aspartate availability on lysine formation by a recombinant strain of Corynebacterium glutamicum and utilization of fumarate", APPLIED AND ENVIRONMENTAL MICROBIOLOGY, (198903), vol. 55, no. 3, pages 684 - 688, XP008017685 | - SANO K. ET AL, "Microbial production of L-Lsine III. production by mutants resistant to S-(2-aminoethyl).L-Cysteine", J. GEN. APPL. MICROBIOL., (19700219), vol. 16, pages 373 - 391, XP001320242 | - MORINAGA Y. ET AL, "Expression of Escherichia coli promoters in Brevibacterium lactofermentum using the shuttle vector p.EB003", JOURNAL OF BIOTECHNOLOGY, (1987), vol. 5, doi:doi:10.1016/0168-1656(87)90027-7, pages 305 - 312, XP023944337 DOI: http://dx.doi.org/10.1016/0168-1656(87)90027-7 | - SHIIO I. ET AL, "Concerted inhibition and its reversal by end products of aspartate kinase in Brevibacterium flavum", THE JOURNAL OF BIOCHEMISTRY, (19690612), vol. 65, no. 6, pages 849 - 859 |