EP0833947 - VARIANT PRESENILIN-2 GENES [Right-click to bookmark this link] | Status | The application is deemed to be withdrawn Status updated on 06.02.2004 Database last updated on 22.08.2024 | Most recent event Tooltip | 06.02.2004 | Application deemed to be withdrawn | published on 24.03.2004 [2004/13] | Applicant(s) | For all designated states UNIVERSITY OF SOUTH FLORIDA 4204 East Fowler Avenue Tampa, FL 33620 / US | For all designated states Washington University 1 Brookings Drive St. Louis, MO 63130 / US | For all designated states THE INSTITUTE FOR GENOMIC RESEARCH 9712 Medical Center Drive Rockville Maryland 20850 / US | [N/P] |
Former [1998/15] | For all designated states University of South Florida 4204 East Fowler Avenue Tampa, FL 33620 / US | ||
For all designated states WASHINGTON UNIVERSITY 1 Brookings Drive St. Louis, MO 63130 / US | |||
For all designated states THE INSTITUTE FOR GENOMIC RESEARCH 9712 Medical Center Drive Rockville, Maryland 20850 / US | Inventor(s) | 01 /
HARDY, John 48 Water Street St. Augustine, FL 32084 / US | 02 /
GOATE, Alison, M. 1177 Claytonia Terrace Richmond Heights, MO 63117 / US | 03 /
FULDNER, Rebecca, A. 21910 Beallsville Road Box 391 Barnesville, MD 20838 / US | [1998/15] | Representative(s) | Crump, Julian Richard John Cleveland 40-43 Chancery Lane London WC2A 1JQ / GB | [N/P] |
Former [1998/35] | Crump, Julian Richard John fJ Cleveland, 40-43 Chancery Lane London WC2A 1JQ / GB | ||
Former [1998/15] | Connell, Anthony Christopher, et al SmithKline Beecham plc Corporate Intellectual Property, Two New Horizons Court Brentford, Middlesex TW8 9EP / GB | Application number, filing date | 97916930.7 | 20.03.1997 | [1998/15] | WO1997US04683 | Priority number, date | US19960014860 | 04.04.1996 Original published format: US 14860 | [1998/15] | Filing language | EN | Procedural language | EN | Publication | Type: | A1 Application with search report | No.: | WO9738133 | Date: | 16.10.1997 | Language: | EN | [1997/44] | Type: | A1 Application with search report | No.: | EP0833947 | Date: | 08.04.1998 | Language: | EN | The application published by WIPO in one of the EPO official languages on 16.10.1997 takes the place of the publication of the European patent application. | [1998/15] | Search report(s) | International search report - published on: | US | 16.10.1997 | (Supplementary) European search report - dispatched on: | EP | 21.05.2003 | Classification | IPC: | C12Q1/68, C07H21/04, C07K14/47 | [2003/26] | CPC: |
C12Q1/6883 (EP);
C07K14/4711 (EP);
C12Q2600/156 (EP)
|
Former IPC [1998/15] | C12Q1/68, C07H21/04 | Designated contracting states | BE, CH, DE, DK, FR, GB, IT, LI, NL [1998/15] | Title | German: | VERSCHIEDENE PRESENILIN-2 GENE | [1998/15] | English: | VARIANT PRESENILIN-2 GENES | [1998/15] | French: | VARIANTS DU GENE PRESENILINE 2 | [1998/15] | Entry into regional phase | 05.01.1998 | National basic fee paid | 05.01.1998 | Search fee paid | 05.01.1998 | Designation fee(s) paid | 16.04.1998 | Examination fee paid | Examination procedure | 16.04.1998 | Examination requested [2000/36] | 05.08.2003 | Application deemed to be withdrawn, date of legal effect [2004/13] | 29.09.2003 | Despatch of communication that the application is deemed to be withdrawn, reason: reply to the communication from the examining division not received in time [2004/13] | Fees paid | Renewal fee | 04.03.1999 | Renewal fee patent year 03 | 06.03.2000 | Renewal fee patent year 04 | 05.03.2001 | Renewal fee patent year 05 | 04.03.2002 | Renewal fee patent year 06 | 05.03.2003 | Renewal fee patent year 07 |
Opt-out from the exclusive Tooltip competence of the Unified Patent Court | See the Register of the Unified Patent Court for opt-out data | ||
Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court. | Documents cited: | Search | [PXY]WO9634099 (ROMMENS JOHANNA M ;FRASER PAUL E (CA); HSC RES DEV LP (CA); UNIV T) [PX] 1-4 * page 10, line 18 - page 11, line 12 * * page 13, line 9 - line 14 * * page 14, line 38 - page 15, line 16 * * page 25, line 12 - page 26, line 7 * * page 33, line 8 - page 34, line 6 * * page 39, line 36 - page 40, line 30 * * page 42, line 35 - page 44, line 36 * * page 81, line 13 - page 91, line 25 * * claims 1,5-7,14,18-25,100,101 * [PY] 5; | [XY] - ROGAEV E I ET AL, "FAMILIAL ALZHEIMER'S DISEASE IN KINDREDS WITH MISSENSE MUTATIONS INA GENE ON CHROMOSOME 1 RELATED TO THE ALZHEIMER'S DISEASE TYPE 3 GENE", NATURE, MACMILLAN JOURNALS LTD. LONDON, GB, (19950831), vol. 376, ISSN 0028-0836, pages 775 - 778, XP000196835 [X] 1-4 *whole document, especially page 775, col. 2, last paragraph* [Y] 5 DOI: http://dx.doi.org/10.1038/376775a0 | [X] - LEVY-LAHAD E ET AL, "CANDIDATE GENE FOR THE CHROMOSOME 1 FAMILIAL ALZHEIMER'S DISEASE LOCUS", SCIENCE, AMERICAN ASSOCIATION FOR THE ADVANCEMENT OF SCIENCE,, US, (19950818), vol. 269, ISSN 0036-8075, pages 973 - 977, XP000616667 [X] 1,4 * page 975, column 1, paragraph 2 - column 3, paragraph 1 * * figure 3 * * page 976, column 3, paragraph 13 - page 977, column 1, paragraph 16 * DOI: http://dx.doi.org/10.1126/science.7638622 | [Y] - PEREZ-TUR J ET AL, "A mutation in Alzheimer's disease destroying a splice acceptor site in the presenilin-1 gene", NEUROREPORT, RAPID COMMUNICATIONS OF OXFORD, OXFORD, GB, (19951229), vol. 7, no. 1, ISSN 0959-4965, pages 297 - 301, XP002114867 [Y] 5 * abstract * * page 298, column 1, paragraph 3 - page 299, column 1, paragraph 1 * * figures 2,3 * | [A] - LEVY-LAHAD E ET AL, "A FAMILIAL ALZHEIMER'S DISEASE LOCUS ON CHROMOSOME I", SCIENCE, AMERICAN ASSOCIATION FOR THE ADVANCEMENT OF SCIENCE,, US, (19950818), vol. 269, no. 5226, ISSN 0036-8075, pages 970 - 973, XP001093899 [A] 1-3 * the whole document * DOI: http://dx.doi.org/10.1126/science.7638621 | [A] - ANWAR R ET AL, "MOLECULAR ANALYSIS OF THE PRESINILIN 1 (S182) GENE IN SPORADIC CASES OF ALZHEIMER'S DISEASE: IDENTIFICATION AND CHARACTERISATION OF UNUSUAL SPLICE VARIANTS", JOURNAL OF NEUROCHEMISTRY, NEW YORK, NY, US, (199604), vol. 66, no. 4, ISSN 0022-3042, pages 1774 - 1777, XP000891244 [A] 5 * the whole document * | [PXA] - LEVY-LAHAD E ET AL, "GENOMIC STRUCTURE AND EXPRESSION OF STM2, THE CHROMOSOME 1 FAMILIAL ALZHEIMER DISEASE GENE", GENOMICS, ACADEMIC PRESS, SAN DIEGO, US, (19960601), vol. 34, no. 2, ISSN 0888-7543, pages 198 - 204, XP002072677 [PX] 1 * abstract * * figure 1 * * table 2 * * page 200, column 1, paragraph L - column 2, paragraph 1 * * page 201, column 1, paragraph L * [PA] 2-5 DOI: http://dx.doi.org/10.1006/geno.1996.0266 | [ ] - GENBANK, (19960708), Database accession no. U50871, URL: GENBANK, XP002236889 [ ] * the whole document * | [PX] - PRIHAR G ET AL, "STRUCTURE AND ALTERNATIVE SPLICING OF THE PRESENILIN-2 GENE", NEUROREPORT, RAPID COMMUNICATIONS OF OXFORD, OXFORD, GB, (199607), vol. 7, no. 10, ISSN 0959-4965, pages 1680 - 1684, XP002921818 [PX] 1-5 * the whole document * | [PX] - CRUTS M ET AL, "THE PRESENILIN GENES: A NEW GENE FAMILY INVOLVED IN ALZHEIMER DISEASE PATHOLOGY", HUMAN MOLECULAR GENETICS, OXFORD UNIVERSITY PRESS, SURREY, GB, (199609), vol. 5, ISSN 0964-6906, pages 1449 - 1455, XP001094396 [PX] 1-3 * abstract * * page 1451, column 1, paragraph 1 - column 2, paragraph 1 * | International search | [T]US5525714 | [T] - AMERICAN J. PATHOLOGY, December 1996, Vol. 149, No. 6, MURPHY G.M. et al., "Antibodies to Presenilin Proteins Detect Neurofibrillary Tangles in Alzheimer's Disease", pages 1839-1845. | [Y] - NATURE MEDICINE, February 1996, Vol. 2, No. 2, KOVACS et al., "Alzheimer-Associated Presenilins 1 and 2: Neuronal Expression in Brain and Localization to Intracellular Membranes in Mammalian Cells", pages 224-229. |