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Extract from the Register of European Patents

EP About this file: EP0955060

EP0955060 - REMEDIES FOR ACUTE PULMONARY INJURIES DUE TO INDIRECT CAUSES CONTAINING ANTI-IL-8 ANTIBODY AS THE ACTIVE INGREDIENT [Right-click to bookmark this link]
StatusThe application has been refused
Status updated on  25.11.2005
Database last updated on 24.01.2025
Most recent event   Tooltip25.11.2005Refusal of applicationpublished on 11.01.2006  [2006/02]
Applicant(s)For all designated states
Chugai Seiyaku Kabushiki Kaisha
5-1, 5-chome, Ukima Kita-ku
Tokyo 115 / JP
[N/P]
Former [1999/45]For all designated states
Chugai Seiyaku Kabushiki Kaisha
5-1, 5-chome, Ukima Kita-ku
Tokyo 115 / JP
Inventor(s)01 / MATSUSHIMA, Kouji
Matsudo Daisanjutaku 2-905, 159-1, Matsudo
Matsudo-shi, Chiba 271 / JP
02 / YOKOI, Kenji
2-4-5, Nomachi
Kanazawa-shi, Ishikawa 921 / JP
[1999/45]
Representative(s)Wakerley, Helen Rachael
Reddie & Grose LLP The White Chapel Building
10 Whitechapel High Street
London E1 8QS / GB
[N/P]
Former [1999/45]Wakerley, Helen Rachael
Reddie & Grose, 16 Theobalds Road
London WC1X 8PL / GB
Application number, filing date97928485.826.06.1997
[1999/45]
WO1997JP02221
Priority number, dateJP1996020091826.06.1996         Original published format: JP 20091896
JP1996031537822.10.1996         Original published format: JP 31537896
[1999/45]
Filing languageJA
Procedural languageEN
PublicationType: A1 Application with search report
No.:WO9749426
Date:31.12.1997
Language:EN
[1997/57]
Type: A1 Application with search report 
No.:EP0955060
Date:10.11.1999
Language:EN
The application published by WIPO in one of the EPO official languages on 31.12.1997 takes the place of the publication of the European patent application.
[1999/45]
Search report(s)International search report - published on:JP31.12.1997
(Supplementary) European search report - dispatched on:EP17.06.1999
ClassificationIPC:A61K39/395, // C07K16/24, C12P21/08
[1999/45]
CPC:
C07K16/24 (EP,US); A61K39/395 (KR); A61P11/00 (EP);
C07K16/244 (EP,US); A61K38/00 (EP,US); C07K2317/24 (EP,US);
C07K2319/00 (EP,US) (-)
Designated contracting statesAT,   BE,   CH,   DE,   DK,   ES,   FI,   FR,   GB,   GR,   IE,   IT,   LI,   LU,   MC,   NL,   PT,   SE [1999/45]
TitleGerman:HEILMITTEL FÜR AKUTE AUF INDIREKTE URSACHEN ZURüCKGEHENDE LUNGENSCHÄDIGUNGEN, DIE EINEN ANTI-IL-8 ANTIKÖRPER ALS WIRKSTOFF ENTHALTEN[1999/45]
English:REMEDIES FOR ACUTE PULMONARY INJURIES DUE TO INDIRECT CAUSES CONTAINING ANTI-IL-8 ANTIBODY AS THE ACTIVE INGREDIENT[1999/45]
French:MEDICAMENTS DESTINES AUX LESIONS PULMONAIRES AIGUES DUES A DES CAUSES INDIRECTES, CONTENANT UN ANTICORPS ANTI-IL-8 COMME PRINCIPE ACTIF[1999/45]
Entry into regional phase24.12.1998Translation filed 
11.01.1999National basic fee paid 
11.01.1999Search fee paid 
11.01.1999Designation fee(s) paid 
11.01.1999Examination fee paid 
Examination procedure25.07.1997Request for preliminary examination filed
International Preliminary Examining Authority: JP
11.01.1999Examination requested  [1999/45]
11.10.2002Despatch of a communication from the examining division (Time limit: M06)
12.03.2003Reply to a communication from the examining division
25.04.2003Despatch of a communication from the examining division (Time limit: M04)
15.05.2003Reply to a communication from the examining division
27.05.2003Despatch of a communication from the examining division (Time limit: M06)
26.11.2003Reply to a communication from the examining division
30.06.2005Date of oral proceedings
26.07.2005Despatch of communication that the application is refused, reason: substantive examination [2006/02]
26.07.2005Minutes of oral proceedings despatched
04.08.2005Application refused, date of legal effect [2006/02]
Fees paidRenewal fee
14.06.1999Renewal fee patent year 03
13.06.2000Renewal fee patent year 04
13.06.2001Renewal fee patent year 05
12.06.2002Renewal fee patent year 06
12.06.2003Renewal fee patent year 07
14.06.2004Renewal fee patent year 08
14.06.2005Renewal fee patent year 09
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Documents cited:Search[XY]WO9523865  (GENENTECH INC [US], et al) [X] 1-6,11-21,26 * page 1, line 21 - line 33 * * page 11, line 28 - page 12, line 5 * * page 35, line 18 - page 36, line 5 *;; claims 1,5,6,26 * [Y] 8-10,23-25;
 [X]WO9204372  (SCRIPPS RESEARCH INST [US]) [X] 1-6,11-21,26 * page 1, line 30 - page 2, line 34; claims 13,14 *;
 [XY]  - SEKIDO, NOBUAKI ET AL, "Prevention of lung reperfusion injury in rabbits by a monoclonal antibody against interleukin - 8.", NATURE (LONDON), (1993), vol. 365, no. 6447, pages 655 - 657, XP000604920 [X] 1-7,11-22,26 * the whole document * [Y] 8-10,23-25

DOI:   http://dx.doi.org/10.1038/365654a0
 [X]  - MULLIGAN M S ET AL, "Inhibition of lung inflammatory reactions in rats by anti-human IL-8 antibody.", THE JOURNAL OF IMMUNOLOGY, (19930615), vol. 150, no. 12, pages 5585 - 95, XP000604925 [X] 1-6,11-21,26 * abstract *
 [X]  - BOYLAN A M ET AL, "Evidence of a role for mesothelial cell-derived interleukin 8 in the pathogenesis of asbestos-induced pleurisy in rabbits.", JOURNAL OF CLINICAL INVESTIGATION, (199204), vol. 89, pages 1257 - 67, XP000603440 [X] 1-6,11-21,26 * abstract *

DOI:   http://dx.doi.org/10.1172/JCI115710
International search[XP]WO9622785  (UNIV CALIFORNIA [US]);
 [Y]WO9602576  (CHUGAI PHARMACEUTICAL CO LTD [JP], et al)
 [X]  - J. CLIN. INVEST., 1995, Vol. 155, "Acid Aspiration-Induced Lung Injury in Rabbits is Mediated by Interleukin-8-Dependant Mechanisms", pp. 107-116.
 [Y]  - CYTOKINE, 1995, Vol. 7, No. 7, "Interleukin 8-Related Neutrophil Elastase and the Severity of the Adult Respiratory Distress Syndrome", pp. 746-752.
 [Y]  - AM. J. RESPIR. CELL. MOL. BIOL., 1992, Vol. 7, "Synthetic Surfactant (Exosurf) Inhibits Endotoxin-Stimulated Cytokine Secretion by Human Alveolar Macrophages", pp. 257-260.
The EPO accepts no responsibility for the accuracy of data originating from other authorities; in particular, it does not guarantee that it is complete, up to date or fit for specific purposes.