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EP About this file: EP0946721

EP0946721 - HUMAN GROWTH GENE AND SHORT STATURE GENE REGION [Right-click to bookmark this link]
Status	No opposition filed within time limit Status updated on 24.10.2003 Database last updated on 11.01.2025
Most recent event Tooltip	24.10.2003	No opposition filed within time limit	published on 10.12.2003 [2003/50]
Applicant(s)	For all designated states Rappold-Hörbrand, Gudrun, Dr. Hausackerweg 14 69118 Heidelberg / DE
	[1999/40]
Inventor(s)	01 / RAPPOLD-HOERBRAND, Gudrun Hausackerweg 14 D-69118 Heidelberg / DE
	02 / RAO, Ercole Odenwaldstrasse 11 D-64560 Riedstadt / DE
	[1999/40]
Representative(s)	Köster, Reinhold Werderplatz 9 69120 Heidelberg / DE
	[N/P]
Former [1999/40]	Köster, Reinhold, Dr. Werderplatz 9 69120 Heidelberg / DE
Application number, filing date	97944906.3	29.09.1997
	[1999/40]
	WO1997EP05355
Priority number, date	US19960027633	01.10.1996 Original published format: US 27633
	EP19970100583	16.01.1997 Original published format: EP 97100583
	[1999/40]
Filing language	EN
Procedural language	EN
Publication	Type:	A1 Application with search report
	No.:	WO9814568
	Date:	09.04.1998
	Language:	EN
	[1998/14]
	Type:	A1 Application with search report
	No.:	EP0946721
	Date:	06.10.1999
	Language:	EN
	The application published by WIPO in one of the EPO official languages on 09.04.1998 takes the place of the publication of the European patent application.
	[1999/40]
	Type:	B1 Patent specification
	No.:	EP0946721
	Date:	18.12.2002
	Language:	EN
	[2002/51]
Search report(s)	International search report - published on:	EP	09.04.1998
Classification	IPC:	C12N15/12, C07K14/47, C12Q1/68, A61K38/18, C12N5/10	[2002/08]
	CPC:	C07K14/475 (EP,US); C12N15/11 (KR); A61P3/00 (EP); A61P5/02 (EP); A61P5/06 (EP); C07K14/4702 (EP,US); (+) A01K2217/05 (EP,US); A61K38/00 (EP,US) (-)
	Former IPC [1999/40]	C12N15/12, C07K14/47, C12Q1/68, A61K38/18, A01K67/027, C12N5/10, C07K16/18
Designated contracting states	AT, BE, CH, DE, DK, ES, FI, FR, GB, GR, IE, IT, LI, LU, MC, NL, PT, SE [1999/40]
Extension states	SI	06.04.1999
Title	German:	MENSCHLICHES WACHSTUMSGEN UND MINDERWUCHSE GEN BEREICH	[1999/40]
	English:	HUMAN GROWTH GENE AND SHORT STATURE GENE REGION	[1999/40]
	French:	GENE DE LA CROISSANCE CHEZ L'HOMME ET ZONE DU GENE DE L'INSUFFISANCE STATURALE	[1999/40]
Entry into regional phase	06.04.1999	National basic fee paid
	06.04.1999	Designation fee(s) paid
	06.04.1999	Examination fee paid
Examination procedure	25.03.1998	Request for preliminary examination filed International Preliminary Examining Authority: EP
	06.04.1999	Examination requested [1999/40]
	20.09.1999	Request for accelerated examination filed
	18.01.2000	Despatch of a communication from the examining division (Time limit: M06)
	18.01.2000	Decision about request for accelerated examination - accepted: Yes
	27.05.2000	Reply to a communication from the examining division
	08.09.2000	Despatch of a communication from the examining division (Time limit: M04)
	02.11.2000	Reply to a communication from the examining division
	11.12.2000	Despatch of a communication from the examining division (Time limit: M04)
	09.04.2001	Reply to a communication from the examining division
	08.08.2001	Despatch of a communication from the examining division (Time limit: M04)
	22.08.2001	Reply to a communication from the examining division
	30.01.2002	Despatch of communication of intention to grant (Approval: Yes)
	28.05.2002	Fee for grant paid
	28.05.2002	Fee for publishing/printing paid
	06.06.2002	Communication of intention to grant the patent
Divisional application(s)	EP02011329.6 / EP1260228
Opposition(s)	19.09.2003	No opposition filed within time limit [2003/50]
Fees paid	Renewal fee
	06.04.1999	Renewal fee patent year 03
	13.09.2000	Renewal fee patent year 04
	22.08.2001	Renewal fee patent year 05
	06.09.2002	Renewal fee patent year 06
Opt-out from the exclusive Tooltip competence of the Unified Patent Court	See the Register of the Unified Patent Court for opt-out data
	Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court.
Cited in	International search	[XA] - M. MARRA ET AL, "mj75d03.r1 Soares mouse p3NMF19.5 Mus musculus cDNA clone 481925 5' similar to TR:G1002494 G1002494 ARIX1.", EMBL DATABASE ENTRY MMA59929, ACCESSION NUMBER AA059929, (19960924), XP002052953 [X] 1,2 * abstract * [A] 27
		[X] - M. MARRA ET AL, "mb68b03.r1 Soares mouse p3NMF19.5 Mus musculus cDNA clone 334541 5'similar to SW: HPR1-chick q05437 homeobox protein PRX-1.", EMBL DATABASE ENTRY MM3349, ACCESSION NUMBER W1818334, (19960504), XP002052954 [X] 1,2 * abstract *
		[DA] - E. RAO ET AL, "Construction of a cosmid contig spanning the short stature candidate region in the pseudoautosomal region PAR 1.", TURNER SYNDROME IN A LIFE SPAN PERSPECTIVE: RESEARCH AND CLINICAL ASPECTS. PROCEEDINGS OF THE 4TH INTERNATIONAL SYMPOSIIUM ON TURNER SYNDROME, GOTHENBURG, SWEDEN,, EDITED BY ALBERTSO-WIKLAND K, RANKE MB, (19950518), pages 19 - 24, XP002052955 [DA] * the whole document *
		[A] - L. HILLIER ET AL, "zb81a08.s1 Homo sapiens cDNA clone 309974 3' similar to PIR:S29087 S29087 homeotic protein Otx1-mouse", EMBL DATABASE ENTRY HS100314, ACCESSION NUMBER N99100, (19960419), XP002052956 [A] 27 * abstract *
		[DA] - T. OGATA ET AL, "short stature in a girl with partial monosomy of the pseudoautosomal region distal to DXYS15: further evidence for the assignment of the critical region for a pseudoautosomal growth gene(s).", JOURNAL OF MEDICAL GENETICS, (199510), vol. 32, no. 10, pages 831 - 834, XP002052957
		[DA] - A. HENKE ET AL, "Deletions within the pseudoautosomal region help map three new markers and indicate a possible role of this region in linear growth", AMERICAN JOURNAL OF HUMAN GENETICS, (199110), vol. 49, no. 4, pages 811 - 819, XP002052958
		[A] - B.W. SCHÄFER ET AL, "Molecular cloning and characterization of a human PAX-7 cDNA expressed in normal and neoplastic myocytes.", NUCLEIC ACIDS RESEARCH., OXFORD GB, (1994), vol. 22, no. 22, pages 4574 - 4582, XP002052959 [A] 1,2 * figure 1A *
		[PDX] - E. RAO ET AL, "Pseudoautosomal deletions encompassing a novel homeobox gene cause growth failure in idiopathic short stature and Turner syndrome.", NATURE GENETICS, (199704), vol. 16, no. 1, pages 54 - 63, XP002052960 [PDX] 1-28 * the whole document * DOI: http://dx.doi.org/10.1038/ng0597-54
		[PX] - J.W. ELLISON ET AL, "PHOG, a candidate gene for involvement in the short stature of Turner Syndrome.", HUMAN MOLECULAR GENETICS, (199708), vol. 6, no. 8, pages 1341 - 1347, XP002052961 [PX] 1-28 * the whole document * DOI: http://dx.doi.org/10.1093/hmg/6.8.1341
		[PA] - A.C. ROVESCALLI ET AL, "Cloning and characterization of four murine homeobox genes", PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF USA., WASHINGTON US, (19961001), vol. 93, pages 10691 - 10696, XP002052968 [PA] 1,2,8,27 * figures 3,4,6 * DOI: http://dx.doi.org/10.1073/pnas.93.20.10691

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