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Extract from the Register of European Patents

EP About this file: EP0924519

EP0924519 - Process for the determination of a dosing regimen for thrombin inhibitors [Right-click to bookmark this link]
Former [1999/25]Process for determining of a dosage regime for thrombin inhibitors
[2005/23]
StatusNo opposition filed within time limit
Status updated on  10.11.2006
Database last updated on 15.07.2024
Most recent event   Tooltip15.02.2008Lapse of the patent in a contracting statepublished on 19.03.2008  [2008/12]
Applicant(s)For all designated states
Abbott GmbH & Co. KG
Max-Planck-Ring 2
65205 Wiesbaden / DE
[2006/01]
Former [2003/19]For all designated states
Abbott GmbH & Co. KG
Max-Planck-Ring 2
65205 Wiesbaden / DE
Former [1999/25]For all designated states
KNOLL AKTIENGESELLSCHAFT
Knollstrasse 16-20
67061 Ludwigshafen / DE
Inventor(s)01 / Nörtersheuser, Peter Dr.
Am alten Weg 24a
55127 Mainz / DE
02 / Kreis, Siegfried
Buttstädterstrasse 8
67251 Freinsheim / DE
[1999/25]
Representative(s)Grünecker Patent- und Rechtsanwälte PartG mbB
Leopoldstrasse 4
80802 München / DE
[N/P]
Former [2001/41]Grünecker, Kinkeldey, Stockmair & Schwanhäusser Anwaltssozietät
Maximilianstrasse 58
80538 München / DE
Application number, filing date98121054.506.11.1998
[1999/25]
Priority number, dateDE199715568215.12.1997         Original published format: DE 19755682
[1999/25]
Filing languageDE
Procedural languageDE
PublicationType: A2 Application without search report 
No.:EP0924519
Date:23.06.1999
Language:DE
[1999/25]
Type: A3 Search report 
No.:EP0924519
Date:24.10.2001
[2001/43]
Type: B1 Patent specification 
No.:EP0924519
Date:04.01.2006
Language:DE
[2006/01]
Search report(s)(Supplementary) European search report - dispatched on:EP12.09.2001
ClassificationIPC:G01N33/48, G01N33/86, G06F19/00, A61K38/58
[2001/43]
CPC:
A61K38/58 (EP,US); A61P7/00 (EP); A61P7/02 (EP)
Former IPC [1999/25]G01N33/48
Designated contracting statesCH,   DE,   ES,   FR,   GB,   IT,   LI [2002/29]
Former [1999/25]AT,  BE,  CH,  CY,  DE,  DK,  ES,  FI,  FR,  GB,  GR,  IE,  IT,  LI,  LU,  MC,  NL,  PT,  SE 
TitleGerman:Verfahren zur Ermittlung eines Dosierungsschemas für Thrombininhibitoren[1999/25]
English:Process for the determination of a dosing regimen for thrombin inhibitors[2005/23]
French:Procédé de détermination d'un régime posologique pour inhibiteurs de thrombine[2005/23]
Former [1999/25]Process for determining of a dosage regime for thrombin inhibitors
Former [1999/25]Procédé pour déterminer un régime dosage pour les inhibiteurs de thrombine
Examination procedure13.11.2001Examination requested  [2002/02]
01.02.2002Despatch of a communication from the examining division (Time limit: M04)
02.05.2002Reply to a communication from the examining division
26.06.2003Despatch of a communication from the examining division (Time limit: M06)
28.11.2003Reply to a communication from the examining division
04.05.2005Communication of intention to grant the patent
08.09.2005Fee for grant paid
08.09.2005Fee for publishing/printing paid
Opposition(s)05.10.2006No opposition filed within time limit [2006/50]
Fees paidRenewal fee
18.11.2000Renewal fee patent year 03
07.11.2001Renewal fee patent year 04
24.04.2003Renewal fee patent year 05
07.11.2003Renewal fee patent year 06
08.11.2004Renewal fee patent year 07
07.11.2005Renewal fee patent year 08
Penalty fee
Additional fee for renewal fee
30.11.200205   M06   Fee paid on   24.04.2003
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Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court.
Lapses during opposition  TooltipES15.04.2006
[2008/12]
Former [2007/17]ES15.04.2006
Documents cited:Search[AD]WO9316390  (MAX PLANCK GESELLSCHAFT [DE]) [AD] 1-5 * abstract * * page 2, paragraph L - page 3, paragraph 2 * * page 8, paragraph L - page 9, paragraph 2 *;
 [Y]  - POETZSCH B ET AL, "MONITORING OF RECOMBINANT HIRUDIN: ASSESSMENT OF A PLASMA-BASED ECARIN CLOTTING TIME ASSAY", THROMBOSIS RESEARCH,TARRYTOWN, NY,US, (19970601), vol. 86, no. 5, ISSN 0049-3848, pages 373 - 383, XP001000734 [Y] 1-5 * abstract * * page 374, paragraph 2 * * page 380, paragraph L - page 382, paragraph 1 *

DOI:   http://dx.doi.org/10.1016/S0049-3848(97)00082-0
 [Y]  - WAKEFIELD J ET AL, "AN APPLICATION OF BAYESIAN POPULATION PHARMACOKINETIC/PHARMACODYNAMIC MODELS TO DOSE RECOMMENDATION", STATISTICS IN MEDICINE, WILEY, NEW YORK, NY, US, (199505), vol. 14, no. 9/10, ISSN 0277-6715, pages 971 - 986, XP001008622 [Y] 1-5 * abstract * * page 972, paragraph 2 - page 985 *
 [Y]  - MUNGALL D R ET AL, "A PROSPECTIVE RANDOMIZED COMPARISON OF THE ACCURACY OF COMPUTER-ASSISTED VERSUS GUSTO NOMOGRAM-DIRECTED HEPARIN THERAPY", CLINICAL PHARMACOLOGY & THERAPEUTICS, MOSBY-YEAR BOOK, ST LOUIS, MO, US, (199405), vol. 55, ISSN 0009-9236, pages 591 - 596, XP001008447 [Y] 1-5 * abstract * * page 591, column L, paragraph 1 - page 592, column L, paragraph 2 * * page 592, column R, paragraph 2 * * page 593, column L, paragraph 2 - column R, paragraph 1 * * Appendix *
 [A]  - GOMENI R ET AL, "POPULATION KINETICS AND CONDITIONAL ASSESSMENT OF THE OPTIMAL DOSAGE REGIMEN USING THE P-PHARM SOFTWARE PACKAGE", ANTICANCER RESEARCH, HELENIC ANTICANCER INSTITUTE, ATHENS,, GR, (19941108), vol. 14, ISSN 0250-7005, pages 2321 - 2326, XP001008384 [A] 1-5 * abstract * * page 2324, column R, paragraph 4 - page 2326, column L *
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