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Extract from the Register of European Patents

EP About this file: EP0988378

EP0988378 - A METHOD FOR IN VITRO MOLECULAR EVOLUTION OF PROTEIN FUNCTION [Right-click to bookmark this link]
Status	Patent maintained as amended Status updated on 16.10.2009 Database last updated on 26.04.2025
Most recent event Tooltip	02.07.2010	Correction of patent specification	published on 04.08.2010 [2010/31]
Applicant(s)	For all designated states BioInvent International AB Sölvegatan 41 223 70 Lund / SE
	[2009/47]
Former [2003/46]	For all designated states BIOINVENT INTERNATIONAL AB Sölvegatan 41 223 70 Lund / SE
Former [2000/13]	For all designated states BIOINVENT INTERNATIONAL AB Ole Römers väg 12 S-223 70 Lund / SE
Inventor(s)	01 / SÖDERLIND, Ulf, Hans, Eskil Spinnarevägen 5 S-247 35 Södra Sandby / SE
	02 / BORREBAECK, Carl, Arne, Krister Attevägen 8A S-245 62 Hjärup / SE
	[2003/44]
Former [2000/13]	01 / SÖDERLIND, Ulf, Hans, Eskil Spinnarevägen 5 S-247 35 Söndra Sandby / SE
	02 / BORREBAECK, Carl, Arne, Krister Attevägen 8A S-245 62 Hjärup / SE
Representative(s)	Thomas, Philip John Duval, et al Potter Clarkson LLP The Belgrave Centre Talbot Street Nottingham NG1 5GG / GB
	[N/P]
Former [2000/22]	Thomas, Philip John Duval, et al Eric Potter Clarkson, Park View House, 58 The Ropewalk Nottingham NG1 5DD / GB
Former [2000/13]	Cripps, Joanna Elizabeth, et al Mewburn Ellis York House 23 Kingsway GB-London WC2B 6HP / GB
Application number, filing date	98901380.0	26.01.1998
	[2000/13]
	WO1998GB00219
Priority number, date	GB19970001425	24.01.1997 Original published format: GB 9701425
	[2000/13]
Filing language	EN
Procedural language	EN
Publication	Type:	A1 Application with search report
	No.:	WO9832845
	Date:	30.07.1998
	Language:	EN
	[1998/30]
	Type:	A1 Application with search report
	No.:	EP0988378
	Date:	29.03.2000
	Language:	EN
	The application published by WIPO in one of the EPO official languages on 30.07.1998 takes the place of the publication of the European patent application.
	[2000/13]
	Type:	B1 Patent specification
	No.:	EP0988378
	Date:	26.11.2003
	Language:	EN
	[2003/48]
	Type:	B2 New European patent specification
	No.:	EP0988378
	Date:	18.11.2009
	Language:	EN
	[2009/47]
	Type:	B9 Corrected patent specification
	No.:	EP0988378
	Date:	04.08.2010
	[2010/31]
Search report(s)	International search report - published on:	EP	30.07.1998
Classification	IPC:	C12N15/10, C07K16/00, C12Q1/68	[2000/13]
	CPC:	C12N15/102 (EP,US); C07K16/00 (EP,US); C07K16/44 (EP,US); C12N15/1027 (EP,US); C12N15/1031 (EP,US); C12N15/1058 (EP,US); (+) C12N15/1086 (EP,US); C07K2317/622 (EP,US); C07K2317/92 (EP,US); Y10T436/143333 (EP,US) (-)
Designated contracting states	AT, BE, CH, DE, DK, ES, FI, FR, GB, GR, IE, IT, LI, LU, MC, NL, PT, SE [2000/13]
Title	German:	METHODE ZUR IN VITRO MOLEKULAREN EVOLUTION EINER PROTEINFUNKTION	[2000/13]
	English:	A METHOD FOR IN VITRO MOLECULAR EVOLUTION OF PROTEIN FUNCTION	[2000/13]
	French:	PROCEDE D'EVOLUTION MOLECULAIRE IN VITRO DE LA FONCTION PROTEIQUE	[2000/13]
Entry into regional phase	13.08.1999	National basic fee paid
	13.08.1999	Designation fee(s) paid
	13.08.1999	Examination fee paid
Examination procedure	17.08.1998	Request for preliminary examination filed International Preliminary Examining Authority: EP
	13.08.1999	Examination requested [2000/13]
	11.07.2003	Communication of intention to grant the patent
	27.08.2003	Fee for grant paid
	27.08.2003	Fee for publishing/printing paid
Divisional application(s)	EP03076606.7 / EP1352959
Opposition(s)	Opponent(s)	01 19.08.2004 27.09.2004 ADMISSIBLE MAXYGEN INC. 515 Galveston Drive Redwood City, CA 94063 / US Opponent's representative Hallybone, Huw George Carpmaels & Ransford LLP One Southampton Row London WC1B 5HA / GB
		02 23.08.2004 28.09.2004 ADMISSIBLE NOVOZYMES A/S Krogshoejvej 36 2880 Bagsvaerd / DK Opponent's representative Power, David J A Kemp 14 South Square Gray's Inn London WC1R 5JJ / GB
		[N/P]
	Former [2009/51]
	Opponent(s)	01 19.08.2004 27.09.2004 ADMISSIBLE MAXYGEN INC. 515 Galveston Drive Redwood City, CA 94063 / US Opponent's representative Hallybone, Huw George Carpmaels & Ransford 43-45 Bloomsbury Square London WC1A 2RA / GB
		02 23.08.2004 28.09.2004 ADMISSIBLE NOVOZYMES A/S Krogshoejvej 36 2880 Bagsvaerd / DK Opponent's representative Power, David J.A. Kemp & Co. 14 South Square Gray's Inn GB-London WC1R 5JJ / GB
	Former [2007/17]
	Opponent(s)	01 19.08.2004 27.09.2004 ADMISSIBLE MAXYGEN Inc. 515 Galveston Drive Redwood City, CA 94063 / US Opponent's representative Hallybone, Huw George Carpmaels and Ransford, 43-45 Bloomsbury Square London WC1A 2RA / GB
		02 23.08.2004 28.09.2004 ADMISSIBLE NOVOZYMES A/S Krogshoejvej 36 2880 Bagsvaerd / DK Opponent's representative Power, David J.A. Kemp & Co. 14 South Square Gray's Inn GB-London WC1R 5JJ / GB
	Former [2004/47]
	Opponent(s)	01 19.08.2004 27.09.2004 ADMISSIBLE MAXYGEN Inc. 515 Galveston Drive Redwood City, CA 94063 / US Opponent's representative Hallybone, Huw George Carpmaels and Ransford, 43-45 Bloomsbury Square London WC1A 2RA / GB
		02 23.08.2004 28.09.2004 ADMISSIBLE NOVOZYMES A/S Krogshoejvej 36 2880 Bagsvaerd / DK Opponent's representative Campbell, Patrick John Henry J.A. Kemp & Co., 14 South Square, Gray's Inn London WC1R 5JJ / GB
	Former [2004/43]
	Opponent(s)	01 19.08.2004 Maxygen ApS Agern Allé 1 2970 Hoersholm / DK Opponent's representative Hallybone, Huw George Carpmaels and Ransford, 43-45 Bloomsbury Square London WC1A 2RA / GB
		02 23.08.2004 NOVOZYMES A/S Krogshoejvej 36 2880 Bagsvaerd / DK Opponent's representative Campbell, Patrick John Henry J.A. Kemp & Co., 14 South Square, Gray's Inn London WC1R 5JJ / GB
	Former [2004/42]
	Opponent(s)	01 19.08.2004 Maxygen ApS Agern Allé 1 2970 Hoersholm / DK Opponent's representative Hallybone, Huw George Carpmaels and Ransford, 43-45 Bloomsbury Square London WC1A 2RA / GB
	04.10.2004	Invitation to proprietor to file observations on the notice of opposition
	06.06.2005	Reply of patent proprietor to notice(s) of opposition
	16.03.2006	Date of oral proceedings
	26.05.2006	Despatch of minutes of oral proceedings
	26.05.2006	Despatch of communication that the patent will be revoked
	05.03.2009	Cancellation of oral proceeding that was planned for 05.05.2009
	05.03.2009	Despatch of minutes of oral proceedings
	18.03.2009	Despatch of interlocutory decision in opposition
	28.03.2009	Legal effect of interlocutory decision in opposition
	05.05.2009	Date of oral proceedings
	08.07.2009	Despatch of communication that the patent will be maintained as amended
	08.10.2009	Fee for printing new specification paid
Appeal following opposition	21.07.2006	Appeal received No. T1188/06
	25.09.2006	Statement of grounds filed
	18.10.2007	Result of appeal procedure: maintenance in amended form
	18.10.2007	Date of oral proceedings
	24.10.2007	Minutes of the oral proceedings despatched
Fees paid	Renewal fee
	24.01.2000	Renewal fee patent year 03
	11.01.2001	Renewal fee patent year 04
	14.01.2002	Renewal fee patent year 05
	14.01.2003	Renewal fee patent year 06
Opt-out from the exclusive Tooltip competence of the Unified Patent Court	See the Register of the Unified Patent Court for opt-out data
	Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court.
Cited in	International search	[A]US5023171 (HO STEFFAN N [US], et al) [A] 1-19 * the whole document *;
		[A]EP0456304 (EASTMAN KODAK CO [US]) [A] 1-19 * the whole document *;
		[A]WO9412632 (UNIV LONDON [GB], et al) [A] 1-19 * the whole document *;
		[A]WO9522625 (AFFYMAX TECH NV [NL], et al) [A] 1-19 * the whole document *;
		[A]WO9617056 (PASTEUR INSTITUT [FR]) [A] 1-19 * the whole document *;
		[DA] - LEUNG D W ET AL, "A METHOD FOR RANDOM MUTAGENESIS OF A DEFINED DNA SEGMENT USING A MODIFIED POLYMERASE CHAIN REACTION", TECHNIQUE, (198908), vol. 1, no. 1, pages 11 - 15, XP000614654 [DA] 1-19 * the whole document *
		[A] - HO S N ET AL, "SITE-DIRECTED MUTAGENESIS BY OVERLAP EXTENSION USING THE POLYMERASE CHAIN REACTION", GENE, (19890101), vol. 77, no. 1, pages 51 - 59, XP000272761 [A] 1-19 * the whole document * DOI: http://dx.doi.org/10.1016/0378-1119(89)90358-2
	Examination	WO9708320
		- SöDERLIND E ET AL, "Domain libraries: Synthetic diversity for de novo design of antibody V-regions", GENE, (1995), vol. 160, pages 269 - 272

The EPO accepts no responsibility for the accuracy of data originating from other authorities; in particular, it does not guarantee that it is complete, up to date or fit for specific purposes.

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