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Extract from the Register of European Patents

EP About this file: EP0979096

EP0979096 - TREATMENT OF INFARCTS THROUGH INHIBITION OF NF-KAPPAB [Right-click to bookmark this link]
Status	No opposition filed within time limit Status updated on 19.03.2004 Database last updated on 24.08.2024
Most recent event Tooltip	16.04.2004	Lapse of the patent in a contracting state New state(s): DK	published on 02.06.2004 [2004/23]
Applicant(s)	For all designated states MILLENNIUM PHARMACEUTICALS, INC. 75 Sidney Street Cambridge Massachusetts 02139 / US
	[N/P]
Former [2003/20]	For all designated states Millennium Pharmaceuticals, Inc. 75 Sidney Street Cambridge, Massachusetts 02139 / US
Former [2001/01]	For all designated states Millennium Pharmaceuticals, Inc. 75 Sidney Street Cambridge, Massachusetts 02139 / US
Former [2000/07]	For all designated states PROSCRIPT, INC. 38 Sidney Street Cambridge, MA 02139 / US
Inventor(s)	01 / BRAND, Stephen 4405 Foxhollow Court San Diego, CA 92130 / US
	02 / GOLDBERG, Alfred, L. 171 Crafts Road Chestnut Hill, MA 02167 / US
	03 / PLAMONDON, Louis 144 Robbins Road Watertown MA 02472 / US
	04 / SOUCY, François 39 Ellen Road Stoneham, MA 02180 / US
	05 / ELLIOT Peter J. 406 Stearns Road Marlborough, MA01752 / US
	[2003/23]
Former [2003/03]	01 / BRAND, Stephen 4405 Foxhollow Court San Diego, CA 92130 / US
	02 / GOLDBERG, Alfred, L. 171 Crafts Road Chestnut Hill, MA 02167 / US
	03 / PLAMONDON, Louis 144 Robbins Road Watertown MA 02472 / US
	04 / SOUCY, François 39 Ellen Road Stoncham, MA 02180 / US
	05 / ELLIOT Peter J. 406 Stearns Road Marlborough, MA01752 / US
Former [2003/01]	01 / BRAND, Stephen 4405 Foxhollow Court San Diego, CA 92130 / US
	02 / GOLDBERG, Alfred, L. 171 Crafts Road Chestnut Hill, MA 02167 / US
	03 / PLAMONDON, Louis 144 Robbins Road Watertown MA 02472 / US
	04 / SOUCY, François 60 Summit Street Arlington, MA 02174 / US
	05 / ELLIOT Peter J. 406 Stearns Road Marlborough, MA01752 / US
Former [2000/21]	01 / BRAND, Stephen 4405 Foxhollow Court San Diego, CA 92130 / US
	02 / GOLDBERG, Alfred, L. 171 Crafts Road Chestnut Hill, MA 02167 / US
	03 / PLAMONDON, Louis 144 ROBBINS ROAD WATERTOWN MA 02472 / US
	04 / SOUCY, François 60 Summit Street Arlington, MA 02174 / US
	05 / ELLIOT Peter J. 406 Stearns Road Marlborough, MA01752 / US
Former [2000/07]	01 / BRAND, Stephen 4405 Foxhollow Court San Diego, CA 92130 / US
	02 / GOLDBERG, Alfred, L. 171 Crafts Road Chestnut Hill, MA 02167 / US
	03 / PLAMONDON, Louis 67 Gilbert Road Belmont, MA 02178 / US
	04 / SOUCY, François 60 Summit Street Arlington, MA 02174 / US
Representative(s)	Vossius, Volker, et al ZSP Patentanwälte PartG mbB Radlkoferstrasse 2 81373 München / DE
	[N/P]
Former [2000/07]	Vossius, Volker, Dr., et al Dr. Volker Vossius, Patentanwaltskanzlei - Rechtsanwaltskanzlei, Holbeinstrasse 5 81679 München / DE
Application number, filing date	98906511.5	17.02.1998
	[2000/07]
	WO1998US03077
Priority number, date	US19970801936	15.02.1997 Original published format: US 801936
	US19970988339	03.12.1997 Original published format: US 988339
	[2000/07]
Filing language	EN
Procedural language	EN
Publication	Type:	A1 Application with search report
	No.:	WO9835691
	Date:	20.08.1998
	Language:	EN
	[1998/33]
	Type:	A1 Application with search report
	No.:	EP0979096
	Date:	16.02.2000
	Language:	EN
	The application published by WIPO in one of the EPO official languages on 20.08.1998 takes the place of the publication of the European patent application.
	[2000/07]
	Type:	B1 Patent specification
	No.:	EP0979096
	Date:	14.05.2003
	Language:	EN
	[2003/20]
Search report(s)	International search report - published on:	EP	20.08.1998
Classification	IPC:	A61K38/05, A61K31/407	[2002/44]
	CPC:	A61K31/407 (EP,US); A61K38/05 (EP,US); A61P9/00 (EP); A61P9/10 (EP)
	Former IPC [2000/07]	A61K38/05, A61K31/40
Designated contracting states	AT, BE, CH, DE, DK, ES, FI, FR, GB, GR, IE, IT, LI, LU, MC, NL, PT, SE [2000/07]
Title	German:	BEHANDLUNG VON INFARKTEN DURCH INHIBIERUNG VON NF-KAPPAB	[2002/44]
	English:	TREATMENT OF INFARCTS THROUGH INHIBITION OF NF-KAPPAB	[2000/07]
	French:	TRAITEMENT D'INFARCTUS PAR INHIBITION DE NF-KAPPAB	[2000/07]
	Former [2000/07]	VERFAHREN ZUR BEHANDLUNG VON INFARKTEN DURCH INHIBIERUNG VON NF-KAPPAB
Entry into regional phase	10.09.1999	National basic fee paid
	10.09.1999	Designation fee(s) paid
	10.09.1999	Examination fee paid
Examination procedure	15.09.1998	Request for preliminary examination filed International Preliminary Examining Authority: EP
	10.09.1999	Examination requested [2000/07]
	25.10.2000	Despatch of a communication from the examining division (Time limit: M04)
	02.03.2001	Reply to a communication from the examining division
	03.05.2001	Despatch of a communication from the examining division (Time limit: M02)
	03.07.2001	Reply to a communication from the examining division
	15.11.2002	Communication of intention to grant the patent
	13.03.2003	Fee for grant paid
	13.03.2003	Fee for publishing/printing paid
Opposition(s)	17.02.2004	No opposition filed within time limit [2004/19]
Fees paid	Renewal fee
	16.02.2000	Renewal fee patent year 03
	20.02.2001	Renewal fee patent year 04
	26.02.2002	Renewal fee patent year 05
	25.02.2003	Renewal fee patent year 06
Opt-out from the exclusive Tooltip competence of the Unified Patent Court	See the Register of the Unified Patent Court for opt-out data
	Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court.
Lapses during opposition Tooltip	DK	14.08.2003
	GR	14.08.2003
	SE	14.08.2003
	[2004/23]
Former [2004/02]	GR	14.08.2003
	SE	14.08.2003
Former [2003/50]	SE	14.08.2003
Cited in	International search	[DA]WO9525533 (HARVARD COLLEGE [US]) [DA] * page 8, line 23 - page 9, line 19 *;
		[DA]WO9613266 (PROSCRIPT INC [US]) [DA] * page 4, line 9 - page 6, line 4 *;
		[DA]WO9632105 (HARVARD COLLEGE [US], et al) [DA] * page 2, line 2 - line 6 * * page 81, line 2 - page 91, line 14 *;
		[A]WO9635430 (FUJISAWA PHARMACEUTICAL CO [JP], et al);
		EP0824918 [ ] (FUJISAWA PHARMACEUTICAL CO [JP]);
		[DA] - ALKALAY ET AL, "STIMULATION -DEPENDENT IKAPPABALPHA PHOSPHORYLATION MARKS THE NF-KAPPAB INHIBITOR FOR DEGRADATION VIA THE UBIQUITIN-PROTEASOME PATHWAY", PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES,USA, (1995), vol. 92, pages 10559 - 10603, XP002066578 [DA] * page 10599 * * abstract * DOI: http://dx.doi.org/10.1073/pnas.92.23.10599
		[DA] - CHEN ET AL, "SITE-SPECIFIC PHOSPHORYLATION OF IKAPPABALPHA BY A NOVEL UBIQUITINATION-DEPENDENT PROTEIN KINASE ACTIVITY", CELL, (19960322), vol. 84, pages 853 - 862, XP002066579 [DA] * page 853 * * abstract * DOI: http://dx.doi.org/10.1016/S0092-8674(00)81064-8
		[DA] - BERLETH ET AL, "MECHANISM OF UBIQUITIN CONJUGATING ENZYME E2-230K: CATALYSIS INVOLVING A THIOL RELAY?", BIOCHEMISTRY, (1996), vol. 35, pages 1664 - 1671, XP002066580 [DA] * page 1664 * * abstract * DOI: http://dx.doi.org/10.1021/bi952105y
		[A] - KOONG ET AL, "HYPOXIA CAUSES THE ACTIVATION OF NUCLEAR FACTOR KAPPAB THROUGH THE PHOSPHORYLATION OF IKAPPABALPHA ON TYROSINE RESIDUES", CANCER RESEARCH, (1994), vol. 54, pages 1425 - 1430, XP002066581 [A] * page 1425 * * abstract *

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