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Extract from the Register of European Patents

EP About this file: EP1007720

EP1007720 - DENDRITIC CELL HYBRIDS [Right-click to bookmark this link]
StatusNo opposition filed within time limit
Status updated on  09.01.2009
Database last updated on 06.07.2024
Most recent event   Tooltip20.05.2011Lapse of the patent in a contracting state
New state(s): GR		published on 22.06.2011  [2011/25]
Applicant(s)For all designated states
DANA FARBER CANCER INSTITUTE, INC.
44 Binney Street Boston
Massachusetts 02154 / US
[2008/10]
Former [2000/24]For all designated states
DANA FARBER CANCER INSTITUTE, INC.
44 Binney Street
Boston Massachusetts 02154 / US
Inventor(s)01 / GONG, Jianlin
20 Winchester Street 7
Brookline, MA 02146 / US
02 / KUFE, Donald
179 Grove Street
Wellesley, MA 02181 / US
[2000/24]
Representative(s)Crump, Julian Richard John, et al
Mintz Levin Cohn Ferris Glovsky & Popeo
Intellectual Property LLP
Alder Castle
10 Noble Street
London EC2V 7JX / GB
[N/P]
Former [2004/30]Crump, Julian Richard John, et al
Mintz Levin Cohn Glovsky and Popeo Intellectual Property LLP The Rectory 9, Ironmonger Lane
London EC2V 8EY / GB
Former [2000/24]Pett, Christopher Phineas, et al
Frank B. Dehn & Co., European Patent Attorneys, 179 Queen Victoria Street
London EC4V 4EL / GB
Application number, filing date98918140.915.04.1998
[2000/24]
WO1998US07353
Priority number, dateUS19970043609P15.04.1997         Original published format: US 43609 P
[2000/24]
Filing languageEN
Procedural languageEN
PublicationType: A1 Application with search report
No.:WO9846785
Date:22.10.1998
Language:EN
[1998/42]
Type: A1 Application with search report 
No.:EP1007720
Date:14.06.2000
Language:EN
The application published by WIPO in one of the EPO official languages on 22.10.1998 takes the place of the publication of the European patent application.
[2000/24]
Type: B1 Patent specification 
No.:EP1007720
Date:05.03.2008
Language:EN
[2008/10]
Search report(s)International search report - published on:US22.10.1998
(Supplementary) European search report - dispatched on:EP12.09.2001
ClassificationIPC:C12P21/00, C12N5/08, C12N5/22, A61K39/00
[2001/43]
CPC:
C12N5/16 (EP,US); A61K39/0011 (US); A61K39/4615 (EP);
A61K39/4622 (EP); A61K39/46447 (EP); A61P1/16 (EP);
A61P31/04 (EP); A61P31/12 (EP); A61P33/02 (EP);
A61P35/00 (EP); A61P37/04 (EP); A61P37/06 (EP);
A61K2039/5152 (US); A61K2039/5154 (US); A61K2039/5156 (US);
A61K2039/5158 (US); A61K2239/38 (EP); A61K38/00 (EP,US);
C12N2501/22 (EP,US); C12N2501/23 (EP,US); C12N2510/00 (EP,US) (-)
Former IPC [2000/24]C12P21/00
Designated contracting statesAT,   BE,   CH,   CY,   DE,   DK,   ES,   FI,   FR,   GB,   GR,   IE,   IT,   LI,   LU,   MC,   NL,   PT,   SE [2000/24]
TitleGerman:DENDRITISCHE ZELLHYBRIDE[2000/24]
English:DENDRITIC CELL HYBRIDS[2000/24]
French:HYBRIDES DE CELLULES DENDRITIQUES[2000/24]
Entry into regional phase15.11.1999National basic fee paid 
15.11.1999Search fee paid 
15.11.1999Designation fee(s) paid 
15.11.1999Examination fee paid 
Examination procedure13.11.1998Request for preliminary examination filed
International Preliminary Examining Authority: US
15.11.1999Examination requested  [2000/24]
19.04.2002Despatch of a communication from the examining division (Time limit: M07)
23.01.2003Reply to a communication from the examining division
03.06.2003Despatch of a communication from the examining division (Time limit: M08)
22.03.2004Despatch of communication that the application is deemed to be withdrawn, reason: reply to the communication from the examining division not received in time
28.05.2004Reply to a communication from the examining division
27.08.2004Despatch of a communication from the examining division (Time limit: M06)
07.03.2005Reply to a communication from the examining division
16.06.2005Despatch of a communication from the examining division (Time limit: M06)
23.12.2005Reply to a communication from the examining division
23.08.2007Cancellation of oral proceeding that was planned for 03.09.2007
03.09.2007Date of oral proceedings (cancelled)
18.09.2007Communication of intention to grant the patent
16.01.2008Fee for grant paid
16.01.2008Fee for publishing/printing paid
Opposition(s)08.12.2008No opposition filed within time limit [2009/07]
Request for further processing for:28.05.2004Request for further processing filed
28.05.2004Full payment received (date of receipt of payment)
Request granted
15.06.2004Decision despatched
23.01.2003Request for further processing filed
23.01.2003Full payment received (date of receipt of payment)
Request granted
11.02.2003Decision despatched
Fees paidRenewal fee
20.03.2000Renewal fee patent year 03
19.03.2001Renewal fee patent year 04
14.03.2002Renewal fee patent year 05
22.04.2003Renewal fee patent year 06
26.04.2004Renewal fee patent year 07
20.04.2005Renewal fee patent year 08
26.04.2006Renewal fee patent year 09
27.04.2007Renewal fee patent year 10
Opt-out from the exclusive  Tooltip
competence of the Unified
Patent Court		 See the Register of the Unified Patent Court for opt-out data
Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court.
Lapses during opposition  TooltipAT05.03.2008
BE05.03.2008
CY05.03.2008
DK05.03.2008
FI05.03.2008
IT05.03.2008
NL05.03.2008
LU15.04.2008
CH30.04.2008
LI30.04.2008
MC30.04.2008
SE05.06.2008
GR06.06.2008
ES16.06.2008
PT05.08.2008
[2011/25]
Former [2010/28]AT05.03.2008
BE05.03.2008
CY05.03.2008
DK05.03.2008
FI05.03.2008
IT05.03.2008
NL05.03.2008
LU15.04.2008
CH30.04.2008
LI30.04.2008
MC30.04.2008
SE05.06.2008
ES16.06.2008
PT05.08.2008
Former [2010/05]AT05.03.2008
BE05.03.2008
CY05.03.2008
DK05.03.2008
FI05.03.2008
IT05.03.2008
NL05.03.2008
CH30.04.2008
LI30.04.2008
MC30.04.2008
SE05.06.2008
ES16.06.2008
PT05.08.2008
Former [2009/12]AT05.03.2008
BE05.03.2008
DK05.03.2008
FI05.03.2008
NL05.03.2008
CH30.04.2008
LI30.04.2008
MC30.04.2008
SE05.06.2008
ES16.06.2008
PT05.08.2008
Former [2009/08]AT05.03.2008
BE05.03.2008
DK05.03.2008
FI05.03.2008
NL05.03.2008
MC30.04.2008
SE05.06.2008
ES16.06.2008
PT05.08.2008
Former [2008/49]AT05.03.2008
BE05.03.2008
FI05.03.2008
NL05.03.2008
MC30.04.2008
SE05.06.2008
ES16.06.2008
PT05.08.2008
Former [2008/46]AT05.03.2008
BE05.03.2008
FI05.03.2008
SE05.06.2008
ES16.06.2008
Former [2008/43]AT05.03.2008
BE05.03.2008
FI05.03.2008
ES16.06.2008
Former [2008/39]AT05.03.2008
FI05.03.2008
ES16.06.2008
Former [2008/35]ES16.06.2008
Documents cited:Search[X]  - MEDLINE, US NATIONAL LIBRARY OF MEDICINE (NLM), BETHESDA, MD, US, XP002167017 [X] 1-26 * abstract *
    [ ] - ZHANG W ET AL, "In vivo induction of antitumor response by tumor cells fused with GM-CSF gene-modified dendritic cells", ZHONGHUA YI XUE ZA ZHI, (199701), vol. 77, no. 1, pages 39 - 42
 [X]  - CELLUZZI CH M & FALO L D, "Immunization with dendritic cells fused with tumor cells elicits potent tumor specific immunity.", JOURNAL OF INVESTIGATIVE DERMATOLOGY, Annual Meeting of the Society for Investigative Dermatology; Washington DC; 23-27 April 1997, (199704), vol. 108, no. 4, page 564, XP000993479 [X] 1-26 * abstract 157 *

DOI:   http://dx.doi.org/10.1111/1523-1747.ep12292095
 [Y]  - GUO YAJUN ET AL, "Effective tumor vaccine generated by fusion of hepatoma cells with activated B cells.", SCIENCE, (19940128), vol. 263, no. 5146, pages 518 - 520, XP002167016 [Y] 1-26 * the whole document *

DOI:   http://dx.doi.org/10.1126/science.7507262
 [Y]  - ZITVOGEL L ET AL, "Therapy of murine tumors with tumor peptide-pulsed dendritic cells: Dependence on T cells, B7 costimulation, and T helper cell 1-associated cytokines.", JOURNAL OF EXPERIMENTAL MEDICINE, (199601), vol. 183, no. 1, pages 87 - 97, XP002910558 [Y] 1-26 * the whole document *

DOI:   http://dx.doi.org/10.1084/jem.183.1.87
International search[AE]WO9817300  (DANA FARBER CANCER INST INC [US]);
 [AP]  - GONG J., ET AL., "INDUCTION OF ANTIGEN-SPECIFIC ANTITUMOR IMMUNITY WITH ADENOVIRUS- TRANSDUCED DENDRITIC CELLS.", Gene Therapy, Nature Publishing Group, GB, GB, (19971001), vol. 04., no. 10., doi:10.1038/sj.gt.3300496, ISSN 0969-7128, pages 1023 - 1028., XP002910552

DOI:   http://dx.doi.org/10.1038/sj.gt.3300496
 [XP]  - GONG J., ET AL., "INDUCTION OF ANTITUMOR ACTIVITY BY IMMUNIZATION WITH FUSIONS OF DENDRITIC AND CARCINOMA CELLS.", NATURE MEDICINE., NATURE PUBLISHING GROUP, NEW YORK, NY., US, US, (19970501), vol. 03., no. 05., doi:10.1038/nm0597-558, ISSN 1078-8956, pages 558 - 561., XP002910553

DOI:   http://dx.doi.org/10.1038/nm0597-558
 [Y]  - GIMMI C. D., ET AL., "BREAST CANCER-ASSOCIATED ANTIGEN, DF3/MUC1, INDUCES APOPTOSIS OF ACTIVATED HUMAN T CELLS.", NATURE MEDICINE., NATURE PUBLISHING GROUP, NEW YORK, NY., US, US, (19961201), vol. 02., no. 12., doi:10.1038/nm1296-1367, ISSN 1078-8956, pages 1367 - 1370., XP002910554

DOI:   http://dx.doi.org/10.1038/nm1296-1367
 [X]  - GONG J., ET AL., "INDUCTION OF ANTITUMOR ACTIVITY BY IMMUNIZATION WITH FUSION OF DENDRIC CELLS AND CARCINOMA CELLS.", Gene Therapy, Nature Publishing Group, GB, GB, (19970301), vol. 38., ISSN 0969-7128, page 616., XP002910555
 [Y]  - CHEN L., ET AL., "TRANSDUCTION OF HUMAN DENDRITIC CELLS WITH TUMOR ASSOCIATED ANTIGENGENES FOR THE GENERATION OF SPECIFIC CYTOTOXIC T IYMPHOCYTES.", PROCEEDINGS OF THE 88TH. ANNUAL MEETING OF THE AMERICAN ASSOCIATION FOR CANCER RESEARCH. SAN DIEGO, APR. 12 - 16, 1997., PHILADELPHIA, AACR., US, US, (19970101), vol. 38., no. 11., page 11., XP002910556
 [XP]  - GONG J. L., ET AL., "FUSION OF HUMAN BREAST TUMOR AND DENDRITIC CELLS AS A NOVEL ANTITUMOR VACCINE.", PROCEEDINGS OF THE 89TH. ANNUAL MEETING OF THE AMERICAN ASSOCIATION FOR CANCER RESEARCH. NEW ORLEANS, LA, MARCH 28 - APRIL 1, 1998., PHILADELPHIA, PA : AACR., US, US, (19980301), vol. 39., page 172., XP002910557
 [Y]  - YCH K.-Y., ET AL., "EXPRESSION OF B7-1 BY PAM 212 SQUAMOUS CELL CARCINOMA ENHANCES TUMOR CELL INTERACTIONS WITH DENDRITIC EPIDERMAL T CELLS BUT DOES NOT AFFECT IN VIVO TUMOR GROWTH.", Journal of Investigative Dermatology, Nature Publishing Group, US, US, (19970101), vol. 109., doi:10.1111/1523-1747.ep12340723, ISSN 0022-202X, pages 728 - 733., XP002910559

DOI:   http://dx.doi.org/10.1111/1523-1747.ep12340723
 [XP]  - GONJ J. L., ET AL., "REVERSAL OF CELL TOLERANCE BY IMMUNIZATION WITH FC/MUC1 DENDRITIC- CARCINOMA FUSIONS IN MUC1 TRANSGENIC MICE.", PROCEEDINGS OF THE 89TH. ANNUAL MEETING OF THE AMERICAN ASSOCIATION FOR CANCER RESEARCH. NEW ORLEANS, LA, MARCH 28 - APRIL 1, 1998., PHILADELPHIA, PA : AACR., US, US, (19980301), vol. 39., page 263., XP002910560
ExaminationWO9817300
    - Moviglia: (1996) Transfus. Sci. 17, 643-649.
    - ZHANG W. ET AL, "Translation of corresponding chinese document", ZHONGHUA YIXUE ZAZHI, (199701), vol. 77, no. 1, pages 39 - 42, XP009011468
    - JOHNSON ET AL, BR. J. CANCER, (2001), vol. 84, no. 10, pages 1424 - 1431
    - Cao et al: (1999) Immunology 97, 616-625.
    - Gong et al: (1997) Gene Ther. 4, 1023-1028.
    - Gong et al: W.B.SAUNDERS COMPANY 3, 558-561.
    - Gimmi et al: (1996) Nature Med. 2, 1360-1370.
    - Gong et al: (1997) Proc. Am. Assoc. Cancer Res. 38, 616.
    - Chen et al: (1997) Proc. Am. Assoc. Cancer Res. 38, 11.
    - Gong et al: (1997) Proc. Am. Assoc. Cancer Res. 39, 172.
    - Gong et al: (1997) Proc. Am. Assoc. Cancer Res. 39, 63.
    - Yeh et al: (1997) J. Invest. Dermatol. 109, 728-733.
    - Hart; Colaco: (1997) Nature 388, 626-627.
The EPO accepts no responsibility for the accuracy of data originating from other authorities; in particular, it does not guarantee that it is complete, up to date or fit for specific purposes.