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Extract from the Register of European Patents

EP About this file: EP0979298

EP0979298 - METASTASIS MODELS USING GREEN FLUORESCENT PROTEIN (GFP) AS A MARKER [Right-click to bookmark this link]
StatusNo opposition filed within time limit
Status updated on  17.04.2009
Database last updated on 20.12.2024
Most recent event   Tooltip30.09.2011Lapse of the patent in a contracting state
New state(s): CY		published on 02.11.2011  [2011/44]
Applicant(s)For all designated states
AntiCancer, Inc.
7917 Ostrow Street
San Diego, CA 92111 / US
[2008/24]
Former [2000/07]For all designated states
ANTICANCER, INC.
7917 Ostrow Street
San Diego, CA 92111 / US
Inventor(s)01 / TAN, Yuying
7575 Linda Vista Road 95
San Diego, CA 92111 / US
02 / CHISHIMA, Takashi
2-14-30 Marigaoka Isogo-ku
Yokohama 235-0024 / JP
[2000/07]
Representative(s)WP Thompson
8th Floor
1 Mann Island
Liverpool L3 1BP / GB
[N/P]
Former [2000/07]W.P. Thompson & Co.
Coopers Building, Church Street
Liverpool L1 3AB / GB
Application number, filing date98918790.128.04.1998
[2000/07]
WO1998US08457
Priority number, dateUS1997084853928.04.1997         Original published format: US 848539
US1998004954427.03.1998         Original published format: US 49544
[2000/07]
Filing languageEN
Procedural languageEN
PublicationType: A1 Application with search report
No.:WO9849336
Date:05.11.1998
Language:EN
[1998/44]
Type: A1 Application with search report 
No.:EP0979298
Date:16.02.2000
Language:EN
The application published by WIPO in one of the EPO official languages on 05.11.1998 takes the place of the publication of the European patent application.
[2000/07]
Type: B1 Patent specification 
No.:EP0979298
Date:11.06.2008
Language:EN
[2008/24]
Search report(s)International search report - published on:EP05.11.1998
ClassificationIPC:C12N15/86, C12N5/10, A01K67/027, C07K14/435
[2000/07]
CPC:
A61K49/0047 (EP,US); A01K67/0271 (EP,US); A61K49/0041 (EP,US);
C07K14/43595 (EP,US); A01K2217/05 (EP,US); A61K48/00 (EP,US)
Designated contracting statesAT,   BE,   CH,   CY,   DE,   DK,   ES,   FI,   FR,   GB,   GR,   IE,   IT,   LI,   LU,   MC,   NL,   PT,   SE [2000/07]
TitleGerman:METASTASEMODELLE UNTER VERWENDUNG DES GRÜN-FLUORESZIERENDEN PROTEINS[2000/07]
English:METASTASIS MODELS USING GREEN FLUORESCENT PROTEIN (GFP) AS A MARKER[2000/07]
French:METASTASES MODELES UTILISANT UNE PROTEINE FLUORESCENTE VERTE (GFP) COMME MARQUEUR[2000/07]
Entry into regional phase05.10.1999National basic fee paid 
05.10.1999Designation fee(s) paid 
05.10.1999Examination fee paid 
Examination procedure09.11.1998Request for preliminary examination filed
International Preliminary Examining Authority: US
05.10.1999Examination requested  [2000/07]
09.12.2002Despatch of a communication from the examining division (Time limit: M06)
19.06.2003Reply to a communication from the examining division
03.07.2003Despatch of a communication from the examining division (Time limit: M06)
13.01.2004Reply to a communication from the examining division
27.03.2006Despatch of a communication from the examining division (Time limit: M04)
25.07.2006Reply to a communication from the examining division
02.02.2007Despatch of a communication from the examining division (Time limit: M04)
29.05.2007Reply to a communication from the examining division
10.08.2007Communication of intention to grant the patent
05.12.2007Fee for grant paid
05.12.2007Fee for publishing/printing paid
Opposition(s)12.03.2009No opposition filed within time limit [2009/21]
Fees paidRenewal fee
07.04.2000Renewal fee patent year 03
09.04.2001Renewal fee patent year 04
08.04.2002Renewal fee patent year 05
07.04.2003Renewal fee patent year 06
06.04.2004Renewal fee patent year 07
04.04.2005Renewal fee patent year 08
17.03.2006Renewal fee patent year 09
12.04.2007Renewal fee patent year 10
28.03.2008Renewal fee patent year 11
Opt-out from the exclusive  Tooltip
competence of the Unified
Patent Court		 See the Register of the Unified Patent Court for opt-out data
Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court.
Lapses during opposition  TooltipAT11.06.2008
CY11.06.2008
DK11.06.2008
FI11.06.2008
IT11.06.2008
NL11.06.2008
SE11.09.2008
GR12.09.2008
ES22.09.2008
PT11.11.2008
[2011/44]
Former [2011/25]AT11.06.2008
DK11.06.2008
FI11.06.2008
IT11.06.2008
NL11.06.2008
SE11.09.2008
GR12.09.2008
ES22.09.2008
PT11.11.2008
Former [2010/05]AT11.06.2008
DK11.06.2008
FI11.06.2008
IT11.06.2008
NL11.06.2008
SE11.09.2008
ES22.09.2008
PT11.11.2008
Former [2009/20]AT11.06.2008
DK11.06.2008
FI11.06.2008
NL11.06.2008
SE11.09.2008
ES22.09.2008
PT11.11.2008
Former [2009/09]AT11.06.2008
FI11.06.2008
NL11.06.2008
SE11.09.2008
ES22.09.2008
PT11.11.2008
Former [2009/07]AT11.06.2008
FI11.06.2008
NL11.06.2008
SE11.09.2008
Former [2009/01]AT11.06.2008
FI11.06.2008
NL11.06.2008
Former [2008/49]AT11.06.2008
FI11.06.2008
Cited inInternational search[PX]WO9745550  (BAXTER INT [US], et al) [PX] 8-10,13 * page 84, line 4 - page 89, line 13; figure 8 *;
 [XDY]  - LEVY J P ET AL, "RETROVIRAL TRANSFER AND EXPRESSION OF A HUMANIZED, RED-SHIFTED GREEN FLUORESCENT PROTEIN GENE INTO HUMAN TUMOR CELLS", NATURE BIOTECHNOLOGY., PUBLISHING US, (199605), vol. 14, no. 5, pages 610 - 614, XP000673366 [XD] 10-12 * page 611, column 1, paragraph 1 * * page 613, column 1, line 11 - line 21 * [Y] 1,6-9,13

DOI:   http://dx.doi.org/10.1038/nbt0596-610
 [X]  - PLAUTZ, J. D. ET AL., "Green fluorescent protein and its derivatives as versatile markers for gene expression in living Drosophila melanogaster, plant and mammalian cells", GENE, AMSTERDAM NL, (1996), vol. 173, pages 83 - 87, XP002073529 [X] 10,11 * page 86, line 2 - line 8 *

DOI:   http://dx.doi.org/10.1016/0378-1119(95)00700-8
 [Y]  - CHALFIE M ET AL, "GREEN FLUORESCENT PROTEIN AS A MARKER FOR GENE EXPRESSION", SCIENCE, (19940211), vol. 263, pages 802 - 805, XP002003599 [Y] 1-16 * page 803, column 3, paragraph 3 *

DOI:   http://dx.doi.org/10.1126/science.8303295
 [YD]  - LIN, W.C. ET AL., "Bacterial lacZ gene as a highly sensitive marker to detect micrometastasis formation during tumor progression", CANCER RESEARCH, (19900501), vol. 50, no. 9, pages 2808 - 2817, XP002078058 [YD] 1-16 * the whole document *
 [Y]  - LIN, W.C. & CULP, L. A., "Altered establishment/clearance mechanisms during experimental micrometastasis with live and/or disabled bacterial lacZ-tagged tumor cells", INVASION METASTASIS, (199205), vol. 12, XP002078059 [Y] 1-16 * released febrary 1993; page 207, column 1, line 26 - line 30 *
 [DPX]  - CHISHISMA, T. ET AL., "Metastatic patterns of lung cancer vizualized live and in process by green fluorescence protein expression", CLINICAL AND EXPERIMENTAL METASTASIS, (199709), vol. 15, no. 5, pages 547 - 552, XP002078061 [DPX] 1-5,7-12,14,15 * the whole document *

DOI:   http://dx.doi.org/10.1023/A:1018431128179
 [DPX]  - CHISHIMA, T. ET AL., "Visualization of the metastatic process by green fluorescent protein expression", ANTICANCER RESEARCH, (199707), vol. 17, no. 4a, pages 2377 - 2384, XP002078062 [DPX] 1-5,7-12,14,15 * the whole document *
 [DPX]  - CHISHIMA, T. ET AL., "Cancer invasion and micrometastasis visualized in live tissue by green fluorescent protein expression", CANCER RESEARCH., MD US, (19970515), vol. 57, no. 10, pages 2042 - 2047, XP002078063 [DPX] 1-5,7-12,14-16 * the whole document *
 [DPX]  - CHISHIMA, T. ET AL., "Governing step of metastasis visualized in vitro", PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF USA., WASHINGTON US, (199710), vol. 94, no. 21, pages 11573 - 11576, XP002078064 [DPX] 1-4,8-13,15 * the whole document *

DOI:   http://dx.doi.org/10.1073/pnas.94.21.11573
 [PX]  - HYER, M.L. ET AL., "Adenovirus-mediated gene transfer of GFP (green fluorescent protein) to mouse and human prostate cancer cells", CANCER GENE THERAPY, (199711), vol. 4, no. 6, pages s29 - s30, XP002078065 [PX] 1-4,6-10,13,15 * the whole document *
 [PY]  - LI Y & HORWITZ, M.S., ""USE OF A GREEN FLUORESCENT PROTEIN IN STUDIES OF APOPTOSIS OF TRANSFECTED CELLLS"", BIOTECHNIQUES, (199712), vol. 23, no. 6, pages 1026 - 1029, XP002068179 [PY] 1-16 * the whole document *
The EPO accepts no responsibility for the accuracy of data originating from other authorities; in particular, it does not guarantee that it is complete, up to date or fit for specific purposes.