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Extract from the Register of European Patents

EP About this file: EP0979273

EP0979273 - MODIFIED ANTISENSE NUCLEOTIDES COMPLEMENTARY TO A SECTION OF THE HUMAN Ha-Ras GENE [Right-click to bookmark this link]
StatusThe application has been withdrawn
Status updated on  20.04.2007
Database last updated on 01.01.2025
Most recent event   Tooltip04.05.2007Application deemed to be withdrawnpublished on 06.06.2007  [2007/23]
Applicant(s)For all designated states
Sanofi-Aventis Deutschland GmbH
Brüningstrasse 50
65929 Frankfurt am Main / DE
[N/P]
Former [2005/44]For all designated states
Sanofi-Aventis Deutschland GmbH
Brüningstrasse 50
65929 Frankfurt am Main / DE
Former [2000/14]For all designated states
Aventis Pharma Deutschland GmbH
Brüningstrasse 50
65929 Frankfurt am Main / DE
Former [2000/07]For all designated states
Hoechst Marion Roussel Deutschland GmbH
Brüningstrasse 50
65929 Frankfurt am Main / DE
Inventor(s)01 / UHLMANN, Eugen
Zum Talblick 31
D-61479 Glashütten / DE
02 / PEYMAN, Anuschirwan
Zeilsheimer Strasse 46
D-65779 Kelkheim / DE
03 / WILL, David, William
Taunusstrasse 9A
D-65824 Schwalbach / DE
04 / CHANG, Esther
7508 Vale Street
Chevy Chase, MD 20815 / US
05 / PIROLLO, Kathleen
Apartment 1031 2001 N. Adams Street
Arlington, VA 22201 / US
06 / RAIT, Antonina
Apartment 4 202 N. Rolfe Street
Arlington, VA 22209 / US
[2000/07]
Application number, filing date98925504.730.04.1998
[2000/07]
WO1998EP02546
Priority number, dateEP1997010740405.05.1997         Original published format: EP 97107404
[2000/07]
Filing languageEN
Procedural languageEN
PublicationType: A1 Application with search report
No.:WO9850540
Date:12.11.1998
Language:EN
[1998/45]
Type: A1 Application with search report 
No.:EP0979273
Date:16.02.2000
Language:EN
The application published by WIPO in one of the EPO official languages on 12.11.1998 takes the place of the publication of the European patent application.
[2000/07]
Search report(s)International search report - published on:EP12.11.1998
ClassificationIPC:C12N15/11, C07H21/00, A61K31/70, A61K45/06
[2000/07]
CPC:
C07H21/02 (EP,US); C12N15/113 (KR); A61K48/00 (KR);
A61P35/00 (EP); C12N15/1135 (EP,US); A61K38/00 (EP,US);
C12N2310/11 (EP,US); C12N2310/315 (EP,US); C12N2310/322 (EP,US);
C12N2310/345 (EP,US); C12N2310/351 (EP,US); C12N2310/3531 (EP,US) (-)
Designated contracting statesAT,   BE,   CH,   CY,   DE,   DK,   ES,   FI,   FR,   GB,   GR,   IE,   IT,   LI,   LU,   MC,   NL,   PT,   SE [2000/07]
TitleGerman:MODIFIZIERTE ANTISENSE OLIGONUKLEOTIDE, DIE KOMPLEMENTÄR ZU EINEM ABSCHNITT DES MENSCHLICHEN HA-RAS GEN SIND[2000/07]
English:MODIFIED ANTISENSE NUCLEOTIDES COMPLEMENTARY TO A SECTION OF THE HUMAN Ha-Ras GENE[2000/07]
French:NUCLEOTIDES ANTISENS MODIFIES COMPLEMENTAIRES D'UNE SECTION DU GENE HUMAIN Ha-Ras[2000/07]
Entry into regional phase06.12.1999National basic fee paid 
06.12.1999Designation fee(s) paid 
06.12.1999Examination fee paid 
Examination procedure28.11.1998Request for preliminary examination filed
International Preliminary Examining Authority: EP
06.12.1999Examination requested  [2000/07]
25.07.2003Despatch of a communication from the examining division (Time limit: M06)
03.02.2004Reply to a communication from the examining division
06.07.2004Despatch of a communication from the examining division (Time limit: M06)
16.12.2004Reply to a communication from the examining division
27.06.2005Despatch of a communication from the examining division (Time limit: M03)
23.01.2006Reply to a communication from the examining division
07.09.2006Communication of intention to grant the patent
17.01.2007Fee for grant paid
17.01.2007Fee for publishing/printing paid
18.01.2007Application deemed to be withdrawn, date of legal effect  [2007/23]
23.02.2007Despatch of communication that the application is deemed to be withdrawn, reason: fee for grant / fee for printing not paid in time  [2007/23]
13.04.2007Application withdrawn by applicant  [2007/21]
Request for further processing for:23.01.2006Request for further processing filed
23.01.2006Full payment received (date of receipt of payment)
Request granted
07.02.2006Decision despatched
Fees paidRenewal fee
02.05.2000Renewal fee patent year 03
02.05.2001Renewal fee patent year 04
02.05.2002Renewal fee patent year 05
02.05.2003Renewal fee patent year 06
03.05.2004Renewal fee patent year 07
02.05.2005Renewal fee patent year 08
02.05.2006Renewal fee patent year 09
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Cited inInternational search[DYA]EP0552766  (HOECHST AG [DE]) [DY] 1-3,6-9 * Formula I with page 5, lines 17-18 and 55-58 * [A] 1-3,5;
 [DA]WO9408003  (ISIS PHARMACEUTICALS INC [US], et al) [DA] 1-3,5,10-14,19,20 * page 19, line 12 - page 22, line 30 * * page 33; table 7 * * page 35, line 7 - page 36, line 17 *;
 [Y]WO9408625  (UNIV TEMPLE [US], et al) [Y] 14,16-18,22-44 * page 13, line 18 - page 27 * * page 32, line 15 - line 17 * * example - * * claim - *;
 [YA]EP0653439  (HOECHST AG [DE]) [Y] 1-3,5,10-14,19,20 * page 2, line 50 - page 5, line 20 * * page 6, line 9 - line 23 * * page 10, line 1 - line 15 * [A] 4,6-9;
 [A]EP0688784  (HOECHST AG [DE]) [A] 1-9 * the whole document *;
 [DY]  - BROWN D ET AL, "MODULATION OF RAS EXPRESSION BY ANTI-SENSE, NONIONIC DEOXYOLIGONUCLEOTIDE ANALOGS", ONCOGENE RESEARCH, (1989), vol. 4, no. 4, pages 243 - 252, XP002031619 [DY] 1-45 * page 249, line 12 - page 250 *
 [Y]  - PEYMAN, A. ET AL., "Facile preparation of 3'-derivatized oligodeoxynucleotides", BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, (1995), vol. 5, pages 2469 - 2472, XP002051342 [Y] 1-4 * the whole document *

DOI:   http://dx.doi.org/10.1016/0960-894X(95)00433-T
 [DY]  - PIROLLO, K. ET AL., "Evidence supporting a signal transduction pathway leading to the radiation-resistant phenotype in human tumor cells", BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS., ORLANDO, FL US, (1997), vol. 230, pages 196 - 201, XP002041769 [DY] 15,21 * the whole document *

DOI:   http://dx.doi.org/10.1006/bbrc.1996.5922
 [Y]  - BITONTI, A. ET AL., "Regression of human breast tumor xenografts in response to (E)-2'-deoxy-2'-(fluoromethylene)cytidine, an inhibitor of ribonucleoside diphosphate reductase", CANCER RESEARCH., MD US, (19940315), vol. 54, pages 1485 - 1490, XP002041770 [Y] 43,44 * the whole document *
 [Y]  - ZON, G. & STEC, W., "Phosphorothioate oligonucleotides", ECKSTEIN, F. 'OLIGONUCLEOTIDES AND ANALOGUES - A PRACTICAL APPROACH', OXFORD UNIVERSITY PRESS; 1991; CHAPTER 4, PAGES 87-108, XP002080898 [Y] 45 * page 97, line 15 - line 27 *
 [DA]  - PEYMAN, A. & UHLMANN, E., "Minimally modified oligonucleotides - combination of end-capping and pyrimidine protection", BIOL. CHEM. HOPPE-SEYLER, (199601), vol. 377, pages 67 - 70, XP002041771
The EPO accepts no responsibility for the accuracy of data originating from other authorities; in particular, it does not guarantee that it is complete, up to date or fit for specific purposes.