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Extract from the Register of European Patents

EP About this file: EP1003856

EP1003856 - APAF-1, THE CED-4 HUMAN HOMOLOG, AN ACTIVATOR OF CASPASE-3 [Right-click to bookmark this link]
StatusThe application is deemed to be withdrawn
Status updated on  04.06.2004
Database last updated on 24.08.2024
Most recent event   Tooltip04.06.2004Application deemed to be withdrawnpublished on 21.07.2004  [2004/30]
Applicant(s)For all designated states
BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM
5323 Harry Hines Boulevard Dallas
Texas 75235-9094 / US
[N/P]
Former [2000/22]For all designated states
Board of Regents, The University of Texas System
5323 Harry Hines Boulevard
Dallas, Texas 75235-9094 / US
Inventor(s)01 / ZOU, Hua
2506A Rampast
Dallas, TX 75235 / US
02 / HENZEL, William, J.
3724 Southwood Avenue
San Mateo, CA 94403 / US
03 / WANG, Xiaodong
4063 Stone Hollow Way
Dallas, TX 75287 / US
[2000/22]
Representative(s)Goldin, Douglas Michael, et al
J.A. KEMP & CO. 14 South Square Gray's Inn
London WC1R 5JJ / GB
[N/P]
Former [2000/22]Goldin, Douglas Michael, et al
J.A. KEMP & CO. 14 South Square Gray's Inn
London WC1R 5LX / GB
Application number, filing date98926395.905.06.1998
[2000/22]
WO1998US11773
Priority number, dateUS19970048807P05.06.1997         Original published format: US 48807 P
US19970055258P07.08.1997         Original published format: US 55258 P
[2000/22]
Filing languageEN
Procedural languageEN
PublicationType: A1 Application with search report
No.:WO9855615
Date:10.12.1998
Language:EN
[1998/49]
Type: A1 Application with search report 
No.:EP1003856
Date:31.05.2000
Language:EN
The application published by WIPO in one of the EPO official languages on 10.12.1998 takes the place of the publication of the European patent application.
[2000/22]
Search report(s)International search report - published on:EP10.12.1998
ClassificationIPC:C12N15/12, C12N15/62, C07K14/47, C07K16/18, C07K19/00, C12N5/10, A61K38/17, G01N33/68, A01K67/027
[2000/22]
CPC:
C07K14/4747 (EP,US); A61P25/00 (EP); A61P35/00 (EP);
A61P37/00 (EP); A61P43/00 (EP); A01K2217/075 (EP,US);
A61K38/00 (EP,US); C07K2319/00 (EP,US) (-)
Designated contracting statesAT,   BE,   CH,   CY,   DE,   DK,   ES,   FI,   FR,   GB,   GR,   IE,   IT,   LI,   LU,   MC,   NL,   PT,   SE [2000/22]
TitleGerman:APAF-1, MENSCHLUCHES CED-4 HOMOLOG, EIN AKTIVATOR VON CASPASE-3[2000/22]
English:APAF-1, THE CED-4 HUMAN HOMOLOG, AN ACTIVATOR OF CASPASE-3[2000/22]
French:APAF-1, HOMOLOGUE HUMAIN DE CED-4, ACTIVATEUR DE CASPASE-3[2000/22]
Entry into regional phase27.12.1999National basic fee paid 
27.12.1999Designation fee(s) paid 
27.12.1999Examination fee paid 
Examination procedure04.01.1999Request for preliminary examination filed
International Preliminary Examining Authority: EP
27.12.1999Examination requested  [2000/22]
17.11.2003Despatch of a communication from the examining division (Time limit: M04)
01.01.2004Application deemed to be withdrawn, date of legal effect  [2004/30]
11.02.2004Despatch of communication that the application is deemed to be withdrawn, reason: renewal fee not paid in time  [2004/30]
Fees paidRenewal fee
13.06.2000Renewal fee patent year 03
13.06.2001Renewal fee patent year 04
12.06.2002Renewal fee patent year 05
Penalty fee
Additional fee for renewal fee
30.06.200306   M06   Not yet paid
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Cited inInternational search[Y]WO9325685  (MASSACHUSETTS INST TECHNOLOGY [US]) [Y] 1-27 * figures 1,3,4; example 1; claims 17-74 *;
 [A]WO9320237  (CAMBRIDGE NEUROSCIENCE INC [US]) [A] 1-4,12-19 * abstract *;
 [X]  - EMEST7 database Accession number N92067 Hillier L. et al. 18-APR-1996 (Rel. 47, Created), XP002078071 [X] 15 * the whole document *
 [Y]  - SPECTOR MS ET AL, "Interaction between the C. elegans cell-death regulators CED-9 and CED-4.", NATURE, FEB 13 1997, 385 (6617) P653-6, ENGLAND, XP002077927 [Y] 1-27 * abstract * * page 655, column R, paragraph 2 *
 [A]  - CHINNAIYAN AM ET AL, "Interaction of CED-4 with CED-3 and CED-9: a molecular framework for cell death [see comments]", SCIENCE, FEB 21 1997, 275 (5303) P1122-6, UNITED STATES, XP002077928 [A] 1-4,12-19,26,27 * abstract * * page 1124, column L, paragraph 2 - page 1126, column L, paragraph 1 *
 [A]  - BAUER, MANUEL K. A. ET AL, "The Caenorhabditis elegans death protein Ced-4 contains a motif with similarity to the mammalian death effector domain", FEBS LETT. (1997), 402(2,3), 256-258 CODEN: FEBLAL;ISSN: 0014-5793, XP002077929 [A] 1-4,12-19 * the whole document *
 [PX]  - ZOU H ET AL, "Apaf-1, a human protein homologous to C. elegans CED-4, participates in cytochrome c-dependent activation of caspase-3 [see comments]", CELL, AUG 8 1997, 90 (3) P405-13, UNITED STATES, XP002077930 [PX] 1-5,9,10,12-19 * the whole document *
The EPO accepts no responsibility for the accuracy of data originating from other authorities; in particular, it does not guarantee that it is complete, up to date or fit for specific purposes.