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Extract from the Register of European Patents

EP About this file: EP1017826

EP1017826 - COMPOSITIONS AND METHODS FOR IDENTIFYING PKB KINASE INHIBITORS [Right-click to bookmark this link]
StatusThe application is deemed to be withdrawn
Status updated on  27.02.2004
Database last updated on 25.09.2024
Most recent event   Tooltip27.02.2004Application deemed to be withdrawnpublished on 14.04.2004  [2004/16]
Applicant(s)For all designated states
ONYX PHARMACEUTICALS
3031 Research Drive, Building A
Richmond, CA 94806-5206 / US
For all designated states
THE BABRAHAM INSTITUTE
Babraham Hall
Babraham, Cambridge CB2 4AT / GB
[2000/49]
Former [2000/28]For all designated states
ONYX PHARMACEUTICALS
3031 Research Drive, Building A
Richmond, CA 94806-5206 / US
Inventor(s)01 / STEPHENS, Len
3 Kingfisher Close
Sawston Cambridge LB2 4JQ / GB
02 / HAWKINGS, Philip
7 South Terrace
Sawston Cambridge CB2 4JQ / GB
03 / STOKOE, David
1221 Gilman Street
Berkeley, CA 94706 / US
[2000/28]
Representative(s)Cripps, Joanna Elizabeth, et al
Mewburn Ellis LLP
City Tower
40 Basinghall Street
London EC2V 5DE / GB
[N/P]
Former [2000/28]Cripps, Joanna Elizabeth, et al
Mewburn Ellis York House 23 Kingsway
GB-London WC2B 6HP / GB
Application number, filing date98947088.517.09.1998
[2000/28]
WO1998US19412
Priority number, dateUS1997006019026.09.1997         Original published format: US 60190
[2000/28]
Filing languageEN
Procedural languageEN
PublicationType: A2 Application without search report
No.:WO9916887
Date:08.04.1999
Language:EN
[1999/14]
Type: A2 Application without search report 
No.:EP1017826
Date:12.07.2000
Language:EN
The application published by WIPO in one of the EPO official languages on 08.04.1999 takes the place of the publication of the European patent application.
[2000/28]
Search report(s)International search report - published on:EP17.06.1999
ClassificationIPC:C12N15/54, C12N9/12, C07K16/40, C12Q1/68, G01N33/50
[2000/28]
CPC:
C12N9/1205 (EP); A61P35/00 (EP); A61P43/00 (EP)
Designated contracting statesAT,   BE,   CH,   CY,   DE,   DK,   ES,   FI,   FR,   GB,   GR,   IE,   IT,   LI,   LU,   MC,   NL,   PT,   SE [2000/28]
TitleGerman:ZUSAMMENSETZUNGEN UND METHODEN ZUR IDENTIFIKATION VON INHIBITOREN DER PKB-KINASE[2000/28]
English:COMPOSITIONS AND METHODS FOR IDENTIFYING PKB KINASE INHIBITORS[2000/28]
French:COMPOSITIONS ET TECHNIQUES PERMETTANT D'IDENTIFIER LES INHIBITEURS DE LA KINASE DE LA PKB[2000/28]
Entry into regional phase08.03.2000National basic fee paid 
08.03.2000Designation fee(s) paid 
08.03.2000Examination fee paid 
Examination procedure06.04.1999Request for preliminary examination filed
International Preliminary Examining Authority: US
08.03.2000Examination requested  [2000/28]
02.04.2003Despatch of a communication from the examining division (Time limit: M06)
13.10.2003Application deemed to be withdrawn, date of legal effect  [2004/16]
14.11.2003Despatch of communication that the application is deemed to be withdrawn, reason: reply to the communication from the examining division not received in time  [2004/16]
Fees paidRenewal fee
04.09.2000Renewal fee patent year 03
24.09.2001Renewal fee patent year 04
23.09.2002Renewal fee patent year 05
24.09.2003Renewal fee patent year 06
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Cited inInternational search[E]WO9841638  (MEDICAL RES COUNCIL) [E] 1-7,9-12,14,15 * the whole document *;
 [DX]WO9722360  (MEDICAL RES COUNCIL ;UNIV DUNDEE (GB); COHEN PHILIP (GB); ALESSI D) [DX] 9 * claim 34 *;
 [DX]  - ALESSI D R ET AL, "Characterization of a 3- phosphoinositide -dependent protein kinase which phosphorylates and activates protein kinase Balpha.", CURRENT BIOLOGY, (19970319), vol. 7, no. 4, pages 261 - 269, XP002070053 [DX] 1-7,14,15 * the whole document *

DOI:   http://dx.doi.org/10.1016/S0960-9822(06)00122-9
 [X]  - ALESSI D R ET AL, "3-phosphoinositide-dependent protein kinase-1 (PDK1): Structural and functional homology with the Drosophila DSTPK61 kinase.", CURRENT BIOLOGY 7 (10). 1997. 776-789. ISSN: 0960-9822, (19970918), XP002070054 [X] 1-12,14,15 * the whole document *

DOI:   http://dx.doi.org/10.1016/S0960-9822(06)00336-8
 [X]  - STOKOE ET AL, "Dual role of phosphatidyl-3,4,5-triphosphate in the activation of protein kinase B", SCIENCE, (19970725), vol. 277, pages 567 - 570, XP002070055 [X] 1-7,14,15 * the whole document *

DOI:   http://dx.doi.org/10.1126/science.277.5325.567
 [X]  - P. COHEN ET AL., "PDK1, one of the missing links in insulin signal transduction?", FEBS LETTERS, ELSEVIER, AMSTERDAM, NL, (19970623), vol. 410, no. 1, pages 3 - 10, XP002098146 [X] 14,15 * the whole document *

DOI:   http://dx.doi.org/10.1016/S0014-5793(97)00490-0
 [DA]  - ALESSI D ET AL, "Mechanism of activation of protein kinase B by insulin and IGF-1", THE EMBO JOURNAL, (1996), vol. 15, no. 23, pages 6541 - 6551, XP002070051 [DA] 1-12,14,15
 [A]  - ALESSI D ET AL, "Molecular basis for the substrate specificity of protein kinase B", FEBS LETTERS, (1996), vol. 399, pages 333 - 338, XP002070052 [A] 1-12,14,15 * the whole document *

DOI:   http://dx.doi.org/10.1016/S0014-5793(96)01370-1
 [A]  - HEMMINGS B A, "PtdIns(3,4,5)P3 gets its message across [comment].", SCIENCE, (19970725), vol. 277, page 534, XP002070056 [A] 1-12,14,15 * the whole document *

DOI:   http://dx.doi.org/10.1126/science.277.5325.534
 [PX]  - L. STEPHENS ET AL., "Protein kinase B kinases that mediate phosphatidylinositol 3,4,5-triphosphate-dependent activation of protein kinase B", SCIENCE, AAAS,WASHINGTON,DC,US, (19980130), vol. 279, pages 710 - 714, XP002098138 [PX] 1-12,14,15 * the whole document *

DOI:   http://dx.doi.org/10.1126/science.279.5351.710
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