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Extract from the Register of European Patents

EP About this file: EP1024811

EP1024811 - NOVEL BENZODIAZEPINE DERIVATIVES AS ANTIARRHYTHMIC AGENTS [Right-click to bookmark this link]
StatusThe application is deemed to be withdrawn
Status updated on  28.06.2003
Database last updated on 20.09.2024
Most recent event   Tooltip28.06.2003Application deemed to be withdrawnpublished on 13.08.2003  [2003/33]
Applicant(s)For all designated states
Merck & Co., Inc.
126 East Lincoln Avenue
Rahway, New Jersey 07065 / US
[N/P]
Former [2000/32]For all designated states
MERCK & CO., INC.
126 East Lincoln Avenue
Rahway, New Jersey 07065 / US
Inventor(s)01 / LIVERTON, Nigel, J.
126 East Lincoln Avenue
Rahway, NJ 07065 / US
02 / BUTCHER, John, W.
126 East Lincoln Avenue
Rahway, NJ 07065 / US
03 / CLAREMON, David, A.
126 East Lincoln Avenue
Rahway, NJ 07065 / US
04 / SELNICK, Harold, G.
126 East Lincoln Avenue
Rahway, NJ 07065 / US
[2000/32]
Representative(s)Hiscock, Ian James, et al
European Patent Department, Merck & Co., Inc., Terlings Park, Eastwick Road
Harlow, Essex CM20 2QR / GB
[N/P]
Former [2000/32]Hiscock, Ian James, et al
European Patent Department, Merck & Co., Inc., Terlings Park, Eastwick Road
Harlow, Essex CM20 2QR / GB
Application number, filing date98953453.213.10.1998
[2000/32]
WO1998US21597
Priority number, dateUS19970062833P17.10.1997         Original published format: US 62833 P
GB1998000668627.03.1998         Original published format: GB 9806686
[2000/32]
Filing languageEN
Procedural languageEN
PublicationType: A1 Application with search report
No.:WO9920281
Date:29.04.1999
Language:EN
[1999/17]
Type: A1 Application with search report 
No.:EP1024811
Date:09.08.2000
Language:EN
The application published by WIPO in one of the EPO official languages on 29.04.1999 takes the place of the publication of the European patent application.
[2000/32]
Search report(s)International search report - published on:US29.04.1999
(Supplementary) European search report - dispatched on:EP30.09.2002
ClassificationIPC:A61K31/55, C07D243/24
[2000/32]
CPC:
C07D243/14 (EP); A61P9/06 (EP); C07D243/24 (EP)
Designated contracting statesAT,   BE,   CH,   CY,   DE,   DK,   ES,   FI,   FR,   GB,   GR,   IE,   IT,   LI,   LU,   NL,   PT,   SE [2000/32]
Extension statesAL17.05.2000
LT17.05.2000
LV17.05.2000
MK17.05.2000
RO17.05.2000
SI17.05.2000
TitleGerman:NEUE BENZODIAZEPINDERIVATE ALS ANTIARRHYTHMISCHE MITTEL[2000/32]
English:NOVEL BENZODIAZEPINE DERIVATIVES AS ANTIARRHYTHMIC AGENTS[2000/32]
French:NOUVEAUX DERIVES DE BENZODIAZEPINE S'UTILISANT COMME AGENTS ANTI-ARYTHMISANTS[2000/32]
Entry into regional phase17.05.2000National basic fee paid 
17.05.2000Search fee paid 
17.05.2000Designation fee(s) paid 
17.05.2000Examination fee paid 
Examination procedure23.04.1999Request for preliminary examination filed
International Preliminary Examining Authority: US
17.05.2000Examination requested  [2000/32]
10.12.2002Application deemed to be withdrawn, date of legal effect  [2003/33]
29.01.2003Despatch of communication that the application is deemed to be withdrawn, reason: filing fee / search fee not paid in time  [2003/33]
Fees paidRenewal fee
31.10.2000Renewal fee patent year 03
31.10.2001Renewal fee patent year 04
Penalty fee
Additional fee for renewal fee
31.10.200205   M06   Not yet paid
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See the Register of the Unified Patent Court for opt-out data
Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court.
Documents cited:Search   [ ] - No further relevant documents disclosed
International search[YP]US5817658  (SIEGL PETER K S [US], et al);
 [YP]WO9748686  (MERCK & CO INC [US], et al);
 [YP]US5776930  (LYNCH JR JOSEPH J [US], et al);
 [Y]US5633251  (CLAREMON DAVID A [US], et al);
 [Y]US5597818  (SANGUINETTI MICHAEL C [US], et al);
 [Y]US5426185  (BALDWIN JOHN J [US], et al);
 [Y]US5004741  (EVANS BEN E [US], et al);
 [Y]US4994258  (BURNS H DONALD [US], et al);
 [Y]US4628084  (BOCK MARK G [US], et al)
 [YP]  - SELNICK H G, ET AL., "CLASS III ANTIARRHYTHMIC ACTIVITY IN VIVO BY SELECTIVE BLOCKADE OF THE SLOWLY ACTIVATING CARDIAC DELAYED RECTIFIER POTASSIUM CURRENT IKS BY (R)-2-(2,4-TRIFLUOROMETHYL)-N-¬2-OXO-5-PHENYL- 1-(2,2,2-TRIFLUOROETHYL)-2,3-DIHYDRO-1H-BENZO¬E3⁄4¬1,43⁄4DIAZEPIN-3-YL3⁄4ACETAMIDE", Journal of Medicinal Chemistry, American Chemical Society, US, US, (19971107), vol. 40, no. 23, doi:10.1021/jm970517u, ISSN 0022-2623, pages 3865 - 3868, XP002916243

DOI:   http://dx.doi.org/10.1021/jm970517u
 [Y]  - TOKARSKI J S, HOPFINGER A J, "THREE-DIMENSIONAL MOLECULAR SHAPE ANALYSIS-QUANTITATIVE STRUCTURE-ACTIVITY RELATIONSHIP OF A SERIES OF CHOLECYSTOKININ-A RECEPTOR ANTAGONISTS", Journal of Medicinal Chemistry, American Chemical Society, US, US, (19941014), vol. 37, no. 21, doi:10.1021/jm00047a021, ISSN 0022-2623, pages 3639 - 3654, XP002916244

DOI:   http://dx.doi.org/10.1021/jm00047a021
 [Y]  - BUREAU R, RAULT S, ROBBA M, "COMPARATIVE MOLECULAR FIELD ANALYSIS OF CCK-B ANTAGONISTS", EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY., EDITIONS SCIENTIFIQUE ELSEVIER, PARIS., FR, FR, (19940101), vol. 29, no. 06, doi:10.1016/0223-5234(94)90076-0, ISSN 0223-5234, pages 487 - 494, XP002916245

DOI:   http://dx.doi.org/10.1016/0223-5234(94)90076-0
The EPO accepts no responsibility for the accuracy of data originating from other authorities; in particular, it does not guarantee that it is complete, up to date or fit for specific purposes.