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Extract from the Register of European Patents

EP About this file: EP1040202

EP1040202 - DNA POLYMORPHISM IDENTITY DETERMINATION USING FLOW CYTOMETRY [Right-click to bookmark this link]
StatusNo opposition filed within time limit
Status updated on  06.11.2009
Database last updated on 25.09.2024
Most recent event   Tooltip30.09.2011Lapse of the patent in a contracting state
New state(s): CY		published on 02.11.2011  [2011/44]
Applicant(s)For all designated states
Los Alamos National Security, LLC
Los Alamos National Laboratory LC/IP, MS A187
Los Alamos, NM 87545 / US
[2008/31]
Former [2006/29]For all designated states
The Regents of the University of California
Los Alamos National Laboratory, LC/IP, MS A187
Los Alamos, NM 87545 / US
Former [2000/40]For all designated states
The Regents of The University of California
Los Alamos National Laboratory, LCP/BPL, MS D412, P.O. Box 1663
Los Alamos, NM 87545 / US
Inventor(s)01 / NOLAN, John, P.
11 Bundy Road
Santa Fe, NM 87501 / US
02 / WHITE, P., Scott
2942 A Orange Street
Los Alamos, NM 87544 / US
03 / CAI, Hong
1997 Cumbres Patio
Los Alamos, NM 87544 / US
[2000/40]
Representative(s)Capasso, Olga, et al
de Simone & Partners
Via Vincenzo Bellini, 20
00198 Roma / IT
[N/P]
Former [2006/29]Capasso, Olga, et al
de Simone & Partners Via Vincenzo Bellini, 20
00198 Roma / IT
Former [2000/40]Wagner, Karl H., Dipl.-Ing., et al
WAGNER & GEYER Patentanwälte Gewürzmühlstrasse 5
80538 München / DE
Application number, filing date98955222.928.10.1998
[2000/40]
WO1998US23143
Priority number, dateUS1997006368528.10.1997         Original published format: US 63685
[2000/40]
Filing languageEN
Procedural languageEN
PublicationType: A1 Application with search report
No.:WO9922030
Date:06.05.1999
Language:EN
[1999/18]
Type: A1 Application with search report 
No.:EP1040202
Date:04.10.2000
Language:EN
The application published by WIPO in one of the EPO official languages on 06.05.1999 takes the place of the publication of the European patent application.
[2000/40]
Type: B1 Patent specification 
No.:EP1040202
Date:31.12.2008
Language:EN
[2009/01]
Type: B9 Corrected patent specification 
No.:EP1040202
Date:23.09.2009
[2009/39]
Search report(s)International search report - published on:US06.05.1999
(Supplementary) European search report - dispatched on:EP01.07.2004
ClassificationIPC:C12Q1/68, C07H21/02, C07H21/04, C12N15/00
[2000/40]
CPC:
C12Q1/6827 (EP,US); C12Q1/6816 (EP,US); C12Q1/6834 (EP,US);
C12Q1/6855 (EP,US); C12Q1/6862 (EP,US); C12Q1/6869 (EP,US)
C-Set:
C12Q1/6816, C12Q2565/626, C12Q2565/519, C12Q2533/107 (EP,US);
C12Q1/6827, C12Q2565/626, C12Q2563/131 (US,EP);
C12Q1/6834, C12Q2565/626, C12Q2565/519, C12Q2533/107 (US,EP);
C12Q1/6855, C12Q2537/143, C12Q2535/125 (US,EP);
C12Q1/6862, C12Q2537/143, C12Q2535/125 (EP,US);
C12Q1/6869, C12Q2565/626, C12Q2563/155, C12Q2563/131 (EP,US)
(-)
Designated contracting statesAT,   BE,   CH,   CY,   DE,   DK,   ES,   FI,   FR,   GB,   GR,   IE,   IT,   LI,   LU,   MC,   NL,   PT,   SE [2000/40]
TitleGerman:IDENTIFIZIERUNG VON DNA-POLYMORPHISMEN MITTELS DURCHFLUSSZYTOMETRIE[2000/40]
English:DNA POLYMORPHISM IDENTITY DETERMINATION USING FLOW CYTOMETRY[2000/40]
French:IDENTIFICATION DE POLYMORPHISMES DE L' ADN PAR CYTOMETRIE DE FLUX[2008/04]
Former [2000/40]IDENTIFICATION DU POLYMORPHISME ADN PAR LA CYTOMETRIE DE FLUX
Entry into regional phase29.05.2000National basic fee paid 
29.05.2000Search fee paid 
29.05.2000Designation fee(s) paid 
29.05.2000Examination fee paid 
Examination procedure16.04.1999Request for preliminary examination filed
International Preliminary Examining Authority: US
29.05.2000Examination requested  [2000/40]
27.01.2005Despatch of a communication from the examining division (Time limit: M06)
08.08.2005Reply to a communication from the examining division
13.09.2005Despatch of a communication from the examining division (Time limit: M08)
20.07.2006Despatch of communication that the application is deemed to be withdrawn, reason: reply to the communication from the examining division not received in time
27.09.2006Reply to a communication from the examining division
04.02.2008Communication of intention to grant the patent
03.06.2008Fee for grant paid
03.06.2008Fee for publishing/printing paid
Divisional application(s)EP08104631.0  / EP2034031
Opposition(s)01.10.2009No opposition filed within time limit [2009/50]
Request for further processing for:27.09.2006Request for further processing filed
27.09.2006Full payment received (date of receipt of payment)
Request granted
17.10.2006Decision despatched
Fees paidRenewal fee
31.10.2000Renewal fee patent year 03
31.10.2001Renewal fee patent year 04
21.10.2002Renewal fee patent year 05
30.10.2003Renewal fee patent year 06
30.10.2004Renewal fee patent year 07
31.10.2005Renewal fee patent year 08
03.10.2006Renewal fee patent year 09
24.10.2007Renewal fee patent year 10
30.09.2008Renewal fee patent year 11
Opt-out from the exclusive  Tooltip
competence of the Unified
Patent Court		 See the Register of the Unified Patent Court for opt-out data
Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court.
Lapses during opposition  TooltipCY31.12.2008
GR01.04.2009
[2011/44]
Former [2011/25]GR01.04.2009
Documents cited:Search[Y]US4962037  (JETT JAMES H [US], et al) [Y] 6,7 * the whole document *;
 [Y]WO9606950  (CHIRON CORP [US]) [Y] 7 * page 3 - page 4 *;
 [Y]US5512439  (HORNES ERIK [NO], et al) [Y] 7 * column 4, paragraph 6 *;
 [Y]WO9714028  (LUMINEX CORP [US], et al) [Y] 5 * claims 75-77 * * page 91, paragraph 3 * * page 11, paragraph 3 *;
 [XY]US5670325  (LAPIDUS STANLEY N [US], et al) [X] 1-4 * claim 38 * * column 5, line 58 - line 63 * * column 6, line 1 - line 26 * * column 16, line 37 - line 66 * * column 17, line 4 - line 28 * [Y] 5-10;
 [T]  - GOOGLE, (19950404) [T] * the whole document *
 [Y]  - FULTON R J ET AL, "Advanced multiplexd analysis with the FlowMetrix(TM) system", CLINICAL CHEMISTRY, AMERICAN ASSOCIATION FOR CLINICAL CHEMISTRY. WINSTON, US, (199709), vol. 43, no. 9, ISSN 0009-9147, pages 1749 - 1756, XP002142645 [Y] 5 * page 1751, column 2, paragraph 3 *
 [Y]  - ROBERTS CHRISTOPHER ET AL, "Synthesis of oligonucleotides bearing the non-standard bases iso-C and iso-G. Comparison of iso-C-iso-G, C-G and U-A base-pair stabilities in RNA/DNA duplexes", TETRAHEDRON LETTERS, (1995), vol. 36, no. 21, ISSN 0040-4039, pages 3601 - 3604, XP002285148 [Y] 7 * the whole document *

DOI:   http://dx.doi.org/10.1016/0040-4039(95)00603-A
 [Y]  - EGGERDING F A ET AL, "FLUORESCENCE-BASED OLIGONUCLEOTIDE LIGATION ASSAY FOR ANALYSIS OF CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR GENE MUTATIONS", HUMAN MUTATION, WILEY-LISS, NEW YORK, NY, US, (1995), vol. 5, no. 2, ISSN 1059-7794, pages 153 - 165, XP001095324 [Y] 8-10 * page 155; figure 1 *

DOI:   http://dx.doi.org/10.1002/humu.1380050209
 [Y]  - BARON H ET AL, "OLIGONUCLEOTIDE LIGATON ASSAY (OLA) FOR THE DIAGNOSIS OF FAMILIAL HYPERCHOLESTEROLEMIA", BIO/TECHNOLOGY, NATURE PUBLISHING CO. NEW YORK, US, (199610), vol. 14, no. 10, ISSN 0733-222X, pages 1279 - 1282, XP001153081 [Y] 8-10 * page 1279; figure 1 *

DOI:   http://dx.doi.org/10.1038/nbt1096-1279
 [A]  - PASTINEN T ET AL, "Multiplex, fluorescent, solid-phase minisequencing for efficient screening of DNA sequence variation", CLINICAL CHEMISTRY. PRINCIPLES AND TECHNICS, NEW YORK, HARPER & ROW, US, (1974), pages 1391 - 1397, XP002116875 [A] * the whole document *
International search[Y]US4770992  (VAN DEN ENGH GERRIT J [US], et al);
 [Y]US5512439  (HORNES ERIK [NO], et al);
 [Y]US5629158  (UHLEN MATHIAS [SE]);
 [YP]US5736330  (FULTON R JERROLD [US]);
 [Y]  - LANDEGREN U., ET AL., "A LIGASE-MEDIATED GENE DETECTION TECHNIQUE.", Science, American Association for the Advancement of Science, US, US, (19880826), vol. 241., doi:10.1126/science.3413476, ISSN 0036-8075, pages 1077 - 1080., XP002916197

DOI:   http://dx.doi.org/10.1126/science.3413476
 [Y]  - UGOZZOLI L., ET AL., "DETECTION OF SPECIFIC ALLELES BY USING ALLELE-SPECIFIC PRIMER EXTENSION FOLLOWED BY CAPTURE ON SOLID SUPPORT.", GENETIC ANALYSIS: BIOMOLECULAR ENGINEERING., ELSEVIER SCIENCE PUBLISHING., US, US, (19920101), vol. 09., no. 04., doi:10.1016/1050-3862(92)90049-B, ISSN 1050-3862, pages 107 - 112., XP002916198

DOI:   http://dx.doi.org/10.1016/1050-3862(92)90049-B
 [Y]  - BAINS M. A., ET AL., "FLOW CYTOMETRIC QUANTITATION OF SEQUENCE-SPECIFIC MRNA IN HEMOPOIETIC CELL SUSPENSIONS BY PRIMER-INDUCED IN SITU (PRINS) FLUORESCENT NUCLEOTIDE LABELING.", EXPERIMENTAL CELL RESEARCH, ACADEMIC PRESS, US, US, (19930101), vol. 208., no. 01., doi:10.1006/excr.1993.1252, ISSN 0014-4827, pages 321 - 326., XP002916199

DOI:   http://dx.doi.org/10.1006/excr.1993.1252
 [Y]  - VLIEGER A. M., ET AL., "QUANTITATION OF POLYMERASE CHAIN REACTION PRODUCTS BY HYBRIDIZATION-BASED ASSAYS WITH FLUORESCENT, COLORIMETRIC, OR CHEMILUMINESCENT DETECTION.", ANALYTICAL BIOCHEMISTRY., ACADEMIC PRESS INC., NEW YORK., NEW YORK., (19920815), vol. 205., no. 01., doi:10.1016/0003-2697(92)90570-W, ISSN 0003-2697, pages 01 - 07., XP002916200

DOI:   http://dx.doi.org/10.1016/0003-2697(92)90570-W
 [XP]  - NOLAN J. P., ET AL., "MICROSPHERE-BASED ASSAYS FOR GENOME ANALYSIS USING FLOW CYTOMETRY.", AMERICAN JOURNAL OF HUMAN GENETICS, AMERICAN SOCIETY OF HUMAN GENETICS, CHICAGO, IL., US, US, (19971028), ISSN 0002-9297, page COMPLETE 01., XP002916301
The EPO accepts no responsibility for the accuracy of data originating from other authorities; in particular, it does not guarantee that it is complete, up to date or fit for specific purposes.