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Extract from the Register of European Patents

EP About this file: EP0965591

EP0965591 - Process for the preparation of (S)-3-methyl-1-(2-piperidino-phenyl)-1-butylamine [Right-click to bookmark this link]
Former [1999/51](s)-3-methyl-1-(2-piperidino-phenyl)-1-butylamine, its salts, synthesis and use in the long term therapy of diabetes mellitus
[2002/03]
StatusNo opposition filed within time limit
Status updated on  11.07.2003
Database last updated on 19.10.2024
Most recent event   Tooltip26.06.2009Change - representativepublished on 29.07.2009  [2009/31]
Applicant(s)For all designated states
Boehringer Ingelheim Pharma GmbH & Co. KG
Binger Strasse 173
55218 Ingelheim am Rhein / DE
[N/P]
Former [2003/24]For all designated states
Boehringer Ingelheim Pharma GmbH & Co.KG
Binger Strasse 173
55218 Ingelheim am Rhein / DE
Former [2000/40]For all designated states
Boehringer Ingelheim Pharma KG
Binger Strasse 173
55218 Ingelheim am Rhein / DE
Former [1999/51]For all designated states
Boehringer Ingelheim Pharma KG
55216 Ingelheim am Rhein / DE
Inventor(s)01 / Grell, Wolfgang Dr. Dipl.-Chem.
Geschwister-Scholl-Strasse 18
88400 Biberach / DE
02 / Greischel, Andreas Dr.
Hugo-Häring-Strasse 78/1
88400 Biberach / DE
03 / Zahn, Gabriele, Frau Dr.
Spieglerstrasse 4
88499 Riedlingen / DE
04 / Mark, Michael Dr.
Hugo-Häring-Strasse 50
88400 Biberach / DE
05 / Knorr, Marianne
Waldstrasse 39
55218 Ingelheim/Rhein / DE
06 / Eckhard, Rupprecht
In den Weinbergen 9
2353 Guntramsdorf / AT
07 / Müller, Ulrich Dr.
Eichenerstrasse 7/1
88441 Biberach-Stafflangen / DE
[1999/51]
Representative(s)Laudien, Dieter, et al
Boehringer Ingelheim GmbH ZA Patente Postfach 200
55216 Ingelheim am Rhein / DE
[2009/31]
Former [2003/33]Laudien, Dieter, Dr., et al
Boehringer Ingelheim GmbH Abteilung Patente, Postfach 200
55216 Ingelheim / DE
Former [2003/25]Vercaemer, Laurence, et al
Cabinet Plasseraud, 84 rue d'Amsterdam
75440 Paris Cedex 09 / FR
Former [1999/51]Laudien, Dieter, Dr.
Boehringer Ingelheim GmbH Abteilung Patente
55216 Ingelheim / DE
Application number, filing date99101810.221.06.1991
[1999/51]
Filing languageDE
Procedural languageDE
PublicationType: A1 Application with search report 
No.:EP0965591
Date:22.12.1999
Language:DE
[1999/51]
Type: B1 Patent specification 
No.:EP0965591
Date:04.09.2002
Language:DE
[2002/36]
Search report(s)(Supplementary) European search report - dispatched on:EP25.10.1999
ClassificationIPC:C07D295/12, A61K31/445
[1999/51]
CPC:
C07D295/135 (EP); A61K31/451 (EP)
Designated contracting statesAT,   BE,   CH,   DE,   DK,   ES,   FR,   GB,   GR,   IT,   LI,   LU,   NL,   SE [1999/51]
TitleGerman:Verfahren zur Herstellung von (S)-3-Methyl-1-(2-piperidino-phenyl)-1-butylamin[2002/03]
English:Process for the preparation of (S)-3-methyl-1-(2-piperidino-phenyl)-1-butylamine[2002/03]
French:Procédé pour la préparation de (S)-3-methyl-1-(2-piperidino-phényl-1-butylamine[2002/03]
Former [1999/51](S)-3-Methyl-1-(2-piperidino-phenyl)-1-butylamin, dessen Salze, Herstellung und Verwendung bei der Langzeittherapie des Diabetes mellitus
Former [1999/51](s)-3-methyl-1-(2-piperidino-phenyl)-1-butylamine, its salts, synthesis and use in the long term therapy of diabetes mellitus
Former [1999/51](s)-3-methyl-1-(2-piperidino-phényl-1-butylamine, ses sels, synthèse et utilisation dans la thérapie de longue durée de la diabète mellitus
Examination procedure23.06.2000Examination requested  [2000/34]
07.06.2001Despatch of a communication from the examining division (Time limit: M04)
29.09.2001Reply to a communication from the examining division
17.10.2001Despatch of a communication from the examining division (Time limit: M04)
16.11.2001Reply to a communication from the examining division
22.01.2002Despatch of communication of intention to grant (Approval: Yes)
04.03.2002Communication of intention to grant the patent
16.05.2002Fee for grant paid
16.05.2002Fee for publishing/printing paid
Parent application(s)   TooltipEP91911959.4  / EP0589874
Opposition(s)05.06.2003No opposition filed within time limit [2003/35]
Fees paidRenewal fee
28.05.1999Renewal fee patent year 03
28.05.1999Renewal fee patent year 04
28.05.1999Renewal fee patent year 05
28.05.1999Renewal fee patent year 06
28.05.1999Renewal fee patent year 07
28.05.1999Renewal fee patent year 08
30.06.1999Renewal fee patent year 09
30.06.2000Renewal fee patent year 10
02.07.2001Renewal fee patent year 11
01.07.2002Renewal fee patent year 12
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Documents cited:Search[A]JPH01131143  ;
 [A]EP0128482  (THOMAE GMBH DR K [DE]) [A] 1-9 * the whole document *;
 [DA]EP0147850  (THOMAE GMBH DR K [DE]) [DA] 1-9 * the whole document *;
 [DX]EP0207331  (THOMAE GMBH DR K [DE]) [DX] 1-5 * Siehe Verbindungen: RN=108157-52-4, RN=108157-53-5 *;; example - *;
 [A]  - GREISCHEL, ANDREAS ET AL, "Quantitation of the new hypoglycemic agent AG-EE 388 ZW in human plasma by automated high-performance liquid chromatography with electrochemical detection", J. CHROMATOGR. (1991), 568(1), 246-52, (1991), XP002117138 [A] 1-5 * the whole document *

DOI:   http://dx.doi.org/10.1016/0378-4347(91)80360-O
 [A]  - "Optical resolution of D,L carnitine nitrile chloride - using N-acetyl- D or L- glutamic acid as resolving agent", DATABASE WPI, 1, Derwent World Patents Index, Database accession no. 1989-195144, XP002117139 & JPH01131143 A 00000000 (EARTH SEIYAKU KK) [A] 6-9 * abstract *
The EPO accepts no responsibility for the accuracy of data originating from other authorities; in particular, it does not guarantee that it is complete, up to date or fit for specific purposes.