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EP1064277
European procedure
Extract from the Register of European Patents
EP About this file: EP1064277
| EP1064277 - 2-(2,6-DIOXOPIPERIDIN-3-YL)ISOINDOLINE DERIVATIVES, THEIR PREPARATION AND THEIR USE AS INHIBITORS OF INFLAMMATORY CYTOKINES [Right-click to bookmark this link] | Status | No opposition filed within time limit Status updated on 12.05.2006 Database last updated on 25.12.2024 | Most recent event Tooltip | 12.05.2006 | No opposition filed within time limit | published on 14.06.2006 [2006/24] | Applicant(s) | For all designated states CELGENE CORPORATION 7 Powder Horn Drive Warren, NJ 07059 / US | [N/P] |
| Former [2001/06] | For all designated states CELGENE CORPORATION 7 Powder Horn Drive Warren New Jersey 07059 / US | ||
| Former [2001/01] | For all designated states Gelgene Corporation 7 Powder Horn Drive Warren, NJ 07059 / US | Inventor(s) | 01 /
MAN, Hon-wah 102 Bermuda Drive Neshanic Station, NJ 08853 / US | 02 /
MULLER, George, W. 250 Windmill Court Bridgewater, NJ 08807 / US | [2001/01] | Representative(s) | Lawrence, John, et al Barker Brettell LLP 100 Hagley Road Edgbaston Birmingham B16 8QQ / GB | [N/P] |
| Former [2001/01] | Lawrence, John, et al Barker Brettell 138 Hagley Road Edgbaston Birmingham B16 9PW / GB | Application number, filing date | 99911393.9 | 16.03.1999 | [2001/01] | WO1999US05562 | Priority number, date | US19980078180P | 16.03.1998 Original published format: US 78180 P | [2001/01] | Filing language | EN | Procedural language | EN | Publication | Type: | A1 Application with search report | No.: | WO9947512 | Date: | 23.09.1999 | Language: | EN | [1999/38] | Type: | A1 Application with search report | No.: | EP1064277 | Date: | 03.01.2001 | Language: | EN | The application published by WIPO in one of the EPO official languages on 23.09.1999 takes the place of the publication of the European patent application. | [2001/01] | Type: | B1 Patent specification | No.: | EP1064277 | Date: | 15.06.2005 | Language: | EN | [2005/24] | Search report(s) | International search report - published on: | EP | 23.09.1999 | Classification | IPC: | C07D401/04, A61K31/445 | [2001/01] | CPC: |
C07D401/04 (EP,KR,US);
A61K31/454 (EP,KR,US);
A61P1/00 (EP);
A61P1/04 (EP);
A61P11/00 (EP);
A61P11/06 (EP);
A61P19/02 (EP);
A61P29/00 (EP);
A61P31/00 (EP);
A61P31/18 (EP);
A61P35/00 (EP);
A61P37/00 (EP);
A61P37/02 (EP);
A61P37/04 (EP);
A61P37/06 (EP);
| Designated contracting states | AT, BE, CH, CY, DE, DK, ES, FI, FR, GB, GR, IE, IT, LI, LU, MC, NL, PT, SE [2001/01] | Extension states | AL | 07.10.2000 | LT | 07.10.2000 | LV | 07.10.2000 | MK | 07.10.2000 | RO | 07.10.2000 | SI | 07.10.2000 | Title | German: | 2-(2,6-DIOXOPIPERIDIN-3-YL)ISOINDOLIN DERIVATE, DEREN HERSTELLUNG UND DEREN VERWENDUNG ALS INHIBITOREN VON ENTZÜNDUNGSZYTOKINEN | [2001/01] | English: | 2-(2,6-DIOXOPIPERIDIN-3-YL)ISOINDOLINE DERIVATIVES, THEIR PREPARATION AND THEIR USE AS INHIBITORS OF INFLAMMATORY CYTOKINES | [2001/01] | French: | DERIVES DE 2-(2,6-DIOXOPIPERIDIN-3-YL)ISO-INDOLINE, LEUR PREPARATION ET LEUR UTILISATION EN TANT QU'INHIBITEURS DE CYTOKINES INFLAMMATOIRES | [2001/01] | Entry into regional phase | 07.10.2000 | National basic fee paid | 07.10.2000 | Designation fee(s) paid | 07.10.2000 | Examination fee paid | Examination procedure | 13.10.1999 | Request for preliminary examination filed International Preliminary Examining Authority: US | 07.10.2000 | Examination requested [2001/01] | 11.04.2002 | Despatch of a communication from the examining division (Time limit: M04) | 25.07.2002 | Reply to a communication from the examining division | 18.10.2002 | Despatch of a communication from the examining division (Time limit: M06) | 24.04.2003 | Reply to a communication from the examining division | 18.12.2003 | Despatch of a communication from the examining division (Time limit: M04) | 23.04.2004 | Reply to a communication from the examining division | 14.12.2004 | Communication of intention to grant the patent | 14.04.2005 | Fee for grant paid | 14.04.2005 | Fee for publishing/printing paid | Divisional application(s) | EP03012168.5 / EP1357120 | Opposition(s) | 16.03.2006 | No opposition filed within time limit [2006/24] | Fees paid | Renewal fee | 05.03.2001 | Renewal fee patent year 03 | 04.03.2002 | Renewal fee patent year 04 | 05.03.2003 | Renewal fee patent year 05 | 29.03.2004 | Renewal fee patent year 06 | 14.03.2005 | Renewal fee patent year 07 |
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| Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court. | Cited in | International search | [X]GB1075420 (GRUENENTHAL CHEMIE) [X] 1,2 * example 31 *; | [Y]WO9214455 (UNIV ROCKEFELLER [US]) [Y] 1-16,18,26 * claims 1,2,6,11,12 *; | [Y]EP0688771 (GRUENENTHAL GMBH [DE]) [Y] 1-16,18,26 * claims 1,2,5,6 *; | [Y]US5635517 (MULLER GEORGE W [US], et al) [Y] 1-16,18,26* the whole document *; | [X]WO9803502 (CELGENE CORP [US], et al) [X] 1-4,18 * claims 1,5-7 *; | [PX]WO9854170 (CELGENE CORP [US], et al) [PX] 1-4,18 * page 10, line 3 - line 23; claims 6,10,12 *; | [PX] - MIYACHI H. ET AL., "Tumor necrosis factor-alpha production enhancing activity of substituted 3'-methylthalidomide: Influence of substituents at the phthaloyl moiety on the activity and stereoselectivity", CHEMICAL & PHARMACEUTICAL BULLETIN, (199807), vol. 46, no. 7, pages 1165 - 1168, XP002107774 [PX] 1,2,4,18 * see compounds (R)-9d and (S)-9d * | [Y] - NIWAYAMA S. ET AL., "Potent inhibition of tumor necrosis factor-.alpha. production by tetrafluorothalidomide and tetrafluorophthalimides", JOURNAL OF MEDICINAL CHEMISTRY, (19960101), vol. 39, no. 16, pages 3044 - 3045, XP002048231 [Y] 1-16,18,26 * the whole document * DOI: http://dx.doi.org/10.1021/jm960284r |