EP1042003 - DELIVERY OF LONG LASTING THERAPEUTIC AGENTS BY FORMING COVALENT ATTACHMENTS IN VIVO [Right-click to bookmark this link] | Status | The application is deemed to be withdrawn Status updated on 03.03.2006 Database last updated on 08.01.2025 | Most recent event Tooltip | 03.03.2006 | Application deemed to be withdrawn | published on 19.04.2006 [2006/16] | Applicant(s) | For all designated states ConjuChem, Inc. 3rd Floor, Suite 3950, 225 President Kennedy Avenue West Montréal, Québec H2X 3Y8 / CA | [N/P] |
Former [2000/41] | For all designated states Conjuchem, Inc. 3rd floor, Suite 3950, 225 President Kennedy Avenue West Montréal, Québec H2X 3Y8 / CA | Inventor(s) | 01 /
EZRIN, Alan, M. 110 Quintas Lane Moraga, CA 94556 / US | 02 /
MILNER, Peter, G. 14690 Manuela Road Los Altos Hills, CA 94022 / US | 03 /
BRIDON, Dominique, P. 243 Chemin Cote Sainte-Catherine Outremont, Quebec H2V 2B2 / CA | 04 /
HOLMES, Darren, L. 3450 Drummond Street Montreal, Quebec H3G 1T3 / CA | [2000/41] | Representative(s) | Walton, Seán Malcolm, et al Mewburn Ellis LLP Aurora Building Counterslip Bristol BS1 6BX / GB | [N/P] |
Former [2000/41] | Walton, Seán Malcolm, et al MEWBURN ELLIS, York House, 23 Kingsway London WC2B 6HP / GB | Application number, filing date | 99916153.2 | 23.03.1999 | [2000/41] | WO1999US06344 | Priority number, date | US19980078974P | 23.03.1998 Original published format: US 78974 P | US19980086352P | 20.05.1998 Original published format: US 86352 P | US19980086205P | 21.05.1998 Original published format: US 86205 P | US19980107391P | 06.11.1998 Original published format: US 107391 P | [2000/41] | Filing language | EN | Procedural language | EN | Publication | Type: | A2 Application without search report | No.: | WO9948536 | Date: | 30.09.1999 | [1999/39] | Type: | A1 Application with search report | No.: | EP1042003 | Date: | 11.10.2000 | Language: | EN | The application published by WIPO in one of the EPO official languages on 30.09.1999 takes the place of the publication of the European patent application. | [2000/41] | Search report(s) | International search report - published on: | EP | 17.05.2001 | Classification | IPC: | A61K47/48, A61K51/04, A61K39/385, A61K51/08 | [2001/32] | CPC: |
A61K47/54 (EP);
A61P17/02 (EP);
A61P31/18 (EP);
A61P35/00 (EP);
A61P9/00 (EP);
A61P9/08 (EP);
A61P9/10 (EP)
(-)
|
Former IPC [2000/41] | A61K47/48 | Designated contracting states | AT, BE, CH, CY, DE, DK, ES, FI, FR, GB, GR, IE, IT, LI, LU, MC, NL, PT, SE [2000/41] | Extension states | AL | 22.12.1999 | LT | 22.12.1999 | LV | 22.12.1999 | RO | 22.12.1999 | SI | 22.12.1999 | Title | German: | VERABREICHUNG ÜBER LÄNGERE ZEIT WIRKSAMER THERAPEUTISCHEN MITTEL DURCH BILDUNG KOVALENTER BINDUNGEN IN VIVO | [2000/41] | English: | DELIVERY OF LONG LASTING THERAPEUTIC AGENTS BY FORMING COVALENT ATTACHMENTS IN VIVO | [2000/41] | French: | APPORT LOCAL D'AGENTS THERAPEUTIQUES A ACTION PROLONGEE | [2000/41] | Entry into regional phase | 22.12.1999 | National basic fee paid | 22.12.1999 | Designation fee(s) paid | 22.12.1999 | Examination fee paid | Examination procedure | 26.12.1999 | Examination requested [2001/23] | 01.10.2005 | Application deemed to be withdrawn, date of legal effect [2006/16] | 15.11.2005 | Despatch of communication that the application is deemed to be withdrawn, reason: renewal fee not paid in time [2006/16] | Fees paid | Renewal fee | 16.03.2001 | Renewal fee patent year 03 | 25.03.2002 | Renewal fee patent year 04 | 28.03.2003 | Renewal fee patent year 05 | 29.03.2004 | Renewal fee patent year 06 | Penalty fee | Additional fee for renewal fee | 31.03.2005 | 07   M06   Not yet paid |
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Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court. | Cited in | International search | [X]JPH04364200 ; | [Y]US4883650 (BHARGAVA KULDEEP K [US], et al) [Y] 1-5,8-13,16,28-32,39-50,52 * example . *; | [Y]WO9416734 (HARVARD COLLEGE [US]) [Y] 1-5,8-13,16,28-32,39-50,52 * example 8 *; | [XY]WO9510302 (REDCELL INC [US]) [X] 1-6,9-14,17-27,33-38,45-51 * examples 4,5 * [Y] 1-52; | [Y]WO9528426 (JOLLA CANCER RES FOUND [US]) [Y] 33-37 * example IIIB *; | [Y]DE19505960 (DEUTSCHES KREBSFORSCH [DE]) [Y] 1-5,8-13,16,28-32,39-50,52 * figures 1,2,4,5,9 *; | [X]US5612034 (POULETTY PHILIPPE [US], et al) [X] 1-6,9-14,17-27,33-38,45-51 * paragraph [EXPERIMENTAL] * * claim - *; | [XY]WO9800171 (REDCELL CANADA INC [CA]) [X] 1-6,9-14,17-27,33-38,45-51 * example - * * claims 10-14,17,18 * [Y] 1-52; | [E]WO9924462 (CONJUCHEM INC [CA], et al) [E] 1-6,9-14,17-27,33-38,45-51 * example - * * sequence number 3 * * claim - *; | [E]WO9924076 (CONJUCHEM INC [CA], et al) [E] 1-52 * example - *; | [Y] - MARTIN V V ET AL, "GADOLINIUM (III) DI- AND TETRACHELATES DESIGNED FOR IN VIVO NONCOVALENT COMPLEXATION WITH PLASMA PROTEINS: A NOVEL MOLECULAR DESIGN FOR BLOOD POOL MRI CONTRAST ENHANCING AGENTS", BIOCONJUGATE CHEMISTRY, (19950901), vol. 6, no. 5, ISSN 1043-1802, pages 616 - 623, XP000542464 [Y] 1-52 * scheme 3; paragraph [DISCUSSION] * DOI: http://dx.doi.org/10.1021/bc00035a017 | [Y] - TOSHIYUKI HIGASHIJIMA ET AL, "DETERMINATION OF AMINO ACIDS BY CAPILLARY ZONE ELECTROPHORESIS BASED ON SEMICONDUCTOR LASER FLUORESCENCE DETECTION", ANALYTICAL CHEMISTRY, (19920401), vol. 64, no. 7, ISSN 0003-2700, pages 711 - 714, XP000277714 [Y] 1-6,9-14,17-27,33-38,45-51 * figures 1,2,6-8 * DOI: http://dx.doi.org/10.1021/ac00031a004 | [Y] - SASAKI K ET AL, "Synthesis and hepatoprotective effects of soyasapogenol B derivatives", BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, (19970107), vol. 7, no. 1, ISSN 0960-894X, page 85-88, XP004135971 [Y] 1-6,9-14,17-27,33-38,45-51 * table 1 * DOI: http://dx.doi.org/10.1016/S0960-894X(96)00572-0 | [Y] - BROWN L ET AL, "COMPARISON OF THE INOTROPIC POTENCIES OF SOME SYNTHETIC AND NATURALLY OCCURRING CARDIAC GLYCOSIDES USING ISOLATED LEFT ATRIUM OF GUINEA PIG", ARZNEIMITTEL FORSCHUNG. DRUG RESEARCH, (19830101), vol. 33, no. 6, ISSN 0004-4172, pages 814 - 817, XP002047422 [Y] 1-6,9-14,17-27,33-38,45-51 * tables 1,3 * * paragraph [RESULTS] * | [Y] - SUZUKI T ET AL, "Biotinylated erythrocytes: in vivo survival and in vitro recovery", BLOOD, 1987, VOL. 70, NO. 3, PAGE(S) 791-5, XP002114026 [Y] 1-6,9-14,17-27,33-38,45-51 * abstract * * page 791, column R * * paragraph [RESULTS] * | [X] - FONG, KEI-LAI L. ET AL, "Clinical pharmacology of IMPY by radioimmunoassay", CANCER TREAT. REP., 1980, VOL. 64, NO. 12, PAGE(S) 1253-1260, XP002122851 [X] 1-5,7,9-13,15 * abstract * * figure 1 * | [XY] - BARANOWSKA-KORTYLEWICZ, JANINA ET AL, "5-Iodo-2'-deoxyuridine-protein conjugates: synthesis and enzymic degradation", SEL. CANCER THER., 1990, VOL. 6, NO. 1, PAGE(S) 1-13, XP002122852 [X] 1-5,7,9-13,15 * abstract * * pages 2-4 * * scheme 1 * [Y] 1-5,8-13,16,28-32,39-50,52 | [Y] - FARGEAS, CHRISTEL ET AL, "Synthetic peptide-based enzyme-linked immunosorbent assay for serodiagnosis of visceral leishmaniasis", J. CLIN. MICROBIOL., FEB. 1996, VOL. 34, NO. 2, PAGE(S) 241-8, XP002122853 [Y] 33-37 * abstract * * page 242, column R * | [X] - PATENT ABSTRACTS OF JAPAN, (19930512), vol. 017, no. 232, Database accession no. (C - 1056), & JP04364200 A 19921216 (UNITIKA LTD) [X] 33-37 * abstract * | [XY] - WILBUR D S, "RADIOHALOGENATION OF PROTEINS: AN OVERVIEW OF RADIONUCLIDES, LABELING METHODS, AND REAGENTS FOR CONJUGATE LABELING", BIOCONJUGATE CHEMISTRY, US, vol. 3, no. 6, ISSN 1043-1802, pages 433 - 470, XP000328382 [X] 1-5,8-13,16,45-50,52 * page 436, paragraph C * * table 4 * [Y] 28-32,39-44 DOI: http://dx.doi.org/10.1021/bc00018a001 | [YP] - SPRADAU, TODD WALTER, "LABELING OF PROTEINS, PEPTIDES, AND ESTROGENS WITH CYCLOPENTADIENYLTRICARBONYLRHENIUM AND TECHNETIUM", DISSERTATION ABSTRACTS, University Microfilms International, Database accession no. AAD99-04593, URL: DIALOG, XP002122858 [YP] 1-5,8-13,16,28-32,39-50,52 * abstract * | [ ] - DISSERTATION ABSTRACTS INTERNATIONAL, (1998), vol. 59, no. 09-B, page 4822 | [Y] - VERBEKE K ET AL, "Comparative evaluation of 99Tcm-Hynic-HSA and 99Tcm-MAG3-HSA as possible blood pool agents.", NUCL MED COMMUN, NOV 1995, VOL. 16, NO. 11, PAGE(S) 942-57, XP002122854 [Y] 1-5,8-13,16,28-32,39-50,52 * abstract * * figures 1,2 * DOI: http://dx.doi.org/10.1097/00006231-199511000-00011 | [Y] - VERBEKE KA ET AL, "First evaluation of technetium-99m dimercaptopropionyl albumin as a possible tracer agent for ventriculography in a volunteer.", EUR J NUCL MED, SEP 1994, VOL. 21, NO. 9, PAGE(S) 906-912, XP002122855 [Y] 1-5,8-13,16,28-32,39-50,52 * abstract * * paragraph MATERIALS AND METHODS * * paragraph ORGAN ACTIVITY RATIOS * DOI: http://dx.doi.org/10.1007/BF00238113 | [Y] - FREUD A ET AL, "A convenient synthesis of N-succinimidyl-3-iodo-[125I]benzoate, a reagent for protein iodination.", INT J RAD APPL INSTRUM [B], AUG 1992, VOL. 19, NO. 6, PAGE(S) 703-704, XP002122856 [Y] 1-5,8-13,16,28-32,39-50,52 * abstract * * page 703, column R * * figures 1,2 * * paragraph RESULTS AND DISCUSSION * DOI: http://dx.doi.org/10.1016/0883-2897(92)90105-8 | [Y] - NAJAFI A ET AL, "Comparison of two methods of labeling proteins with 111In.", INT J RAD APPL INSTRUM [B], 1986, VOL. 13, NO. 4, PAGE(S) 345-346, XP002122857 [Y] 1-5,8-13,16,28-32,39-50,52 * abstract * * tables 1,2 * * page 346, paragraph DISCUSSION * DOI: http://dx.doi.org/10.1016/0883-2897(86)90007-3 |