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Extract from the Register of European Patents

EP About this file: EP1118659

EP1118659 - EXPRESSION SYSTEMS FOR FUNCTIONAL NUCLEIC ACID EXPRESSION [Right-click to bookmark this link]
StatusNo opposition filed within time limit
Status updated on  30.03.2007
Database last updated on 20.12.2024
Most recent event   Tooltip22.05.2009Change - representativepublished on 24.06.2009  [2009/26]
Applicant(s)For all designated states
National Institute of Advanced Industrial Science and Technology
3-1, Kasumigaseki 1-chome
Chiyoda-ku, Tokyo / JP
[2006/13]
Former [2001/30]For all designated states
Japan as represented by Director-General of Agency of Industrial Science and Technology
3-1, Kasumigaseki 1-chome, Chiyoda-ku
Tokyo 100-8921 / JP
Inventor(s)01 / TAIRA, Kazunari
2-4-29, Higashi
Tsukuba-shi, Ibaraki 305-0046 / JP
02 / OHKAWA, Jun
B108, 1055-588, Shimohirooka
Tsukuba-shi, Ibaraki 305-0042 / JP
03 / KOSEKI, Shiori
2-2-6-405, Iidanishi
Yamagata-shi, Yamagata 990-2331 / JP
 [2001/30]
Representative(s)Harding, Charles Thomas, et al
D Young & Co LLP
120 Holborn
London EC1N 2DY / GB
[N/P]
Former [2009/26]Harding, Charles Thomas, et al
D Young & Co 120 Holborn London
EC1N 2DY / GB
Former [2006/13]Khoo, Chong-Yee, et al
D Young & Co 120 Holborn
London EC1N 2DY / GB
Former [2001/30]Khoo, Chong-Yee
D Young & Co, 21 New Fetter Lane
London EC4A 1DA / GB
Application number, filing date99940588.931.08.1999
[2001/30]
WO1999JP04718
Priority number, dateJP1998024475531.08.1998         Original published format: JP 24475598
[2001/30]
Filing languageJA
Procedural languageEN
PublicationType: A1 Application with search report
No.:WO0012686
Date:09.03.2000
Language:EN
[2000/10]
Type: A1 Application with search report 
No.:EP1118659
Date:25.07.2001
Language:EN
The application published by WIPO in one of the EPO official languages on 09.03.2000 takes the place of the publication of the European patent application.
[2001/30]
Type: B1 Patent specification 
No.:EP1118659
Date:12.04.2006
Language:EN
[2006/15]
Search report(s)International search report - published on:JP09.03.2000
(Supplementary) European search report - dispatched on:EP21.10.2002
ClassificationIPC:C12N15/00, C12N9/00, A61K31/00, A61K31/70, A61K35/76, A61K48/00
[2001/30]
CPC:
C12N15/113 (EP,US); A61P31/12 (EP); A61P37/04 (EP);
C12N15/1132 (EP,US); A61K38/00 (EP,US); C07K2319/00 (EP,US);
C12N2310/111 (EP,US); C12N2310/121 (EP,US) (-)
Designated contracting statesDE,   FR,   GB [2004/20]
Former [2001/30]AT,  BE,  CH,  CY,  DE,  DK,  ES,  FI,  FR,  GB,  GR,  IE,  IT,  LI,  LU,  MC,  NL,  PT,  SE 
TitleGerman:EXPRESSIONSSYSTEME ZUR FUNKTIONELLEN EXPRESSION VON NUKLEINSÄUREN[2001/30]
English:EXPRESSION SYSTEMS FOR FUNCTIONAL NUCLEIC ACID EXPRESSION[2001/30]
French:SYSTEMES D'EXPRESSION SERVANT A L'EXPRESSION D'ACIDES NUCLEIQUES FONCTIONNELS[2001/30]
Entry into regional phase22.03.2001Translation filed 
22.03.2001National basic fee paid 
22.03.2001Search fee paid 
22.03.2001Designation fee(s) paid 
22.03.2001Examination fee paid 
Examination procedure30.03.2000Request for preliminary examination filed
International Preliminary Examining Authority: JP
22.03.2001Examination requested  [2001/30]
03.07.2003Despatch of a communication from the examining division (Time limit: M06)
08.01.2004Reply to a communication from the examining division
30.09.2005Communication of intention to grant the patent
25.01.2006Fee for grant paid
25.01.2006Fee for publishing/printing paid
Opposition(s)15.01.2007No opposition filed within time limit [2007/18]
Fees paidRenewal fee
02.08.2001Renewal fee patent year 03
07.08.2002Renewal fee patent year 04
12.08.2003Renewal fee patent year 05
05.08.2004Renewal fee patent year 06
29.07.2005Renewal fee patent year 07
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Documents cited:Search[Y]WO9400012  (GENE SHEARS PTY LTD [AU], et al) [Y] 1-15 * page 10-21 *;
 [A]WO9622368  (GENE SHEARS PTY LTD [AU], et al) [A] 1-15 * the whole document *;
 [Y]  - WEERASINGHE ET AL, "Resistance to human immunodeficiency virus type 1 (HIV-1) infection in human CD4+ lymphocyte-derived cell lines conferred by using retroviral vectors expressing an HIV-1 RNA-specific ribozyme", JOURNAL OF VIROLOGY, NEW YORK, US, US, (19911001), vol. 65, no. 1, ISSN 0022-538X, pages 5531 - 5534, XP002097310 [Y] 1-15 * abstract, page 5531-32 and Fig 1 *
 [Y]  - ROSSI J J ET AL, "RIBOZYMES AS ANTI-HIV-1 THERAPEUTIC AGENTS: PRINCIPLES, APPLICATIONS, AND PROBLEMS", AIDS RESEARCH AND HUMAN RETROVIRUSES, MARY ANN LIEBERT, US, (19920201), vol. 8, no. 2, ISSN 0889-2229, pages 183 - 189, XP002026934 [Y] 1-15 * in particular page 184 bottom right-page 185 *
 [A]  - DOMI A ET AL, "Transcripts containing a small anti-HIV hammerhead ribozyme that are active in the cell cytoplasm but inactive in vitro as free RNAs.", BIOCHIMIE (PARIS), (1996), vol. 78, no. 7, ISSN 0300-9084, pages 654 - 662, XP002212524 [A] 1-15 * the whole document *

DOI:   http://dx.doi.org/10.1016/S0300-9084(96)80011-3
 [A]  - SUN L-Q ET AL, "Ribozyme-mediated suppression of Moloney murine leukemia virus and human immunodeficiency virus type I replication in permissive cells", PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF USA, NATIONAL ACADEMY OF SCIENCE. WASHINGTON, US, (199410), vol. 91, ISSN 0027-8424, pages 9715 - 9719, XP002148091 [A] 1-15 * the whole document *

DOI:   http://dx.doi.org/10.1073/pnas.91.21.9715
 [A]  - HOMANN M ET AL, "INCORPORATION OF THE CATALYTIC DOMAIN OF A HAMMERHEAD RIBOZYME INTOANTISENSE RNA ENHANCES ITS INHIBITORY EFFECT ON THE REPLICATION OF HUMAN IMMUNODEFICIENCY VIRUS TYPE 1", NUCLEIC ACIDS RESEARCH, OXFORD UNIVERSITY PRESS, SURREY, GB, (1993), vol. 21, no. 12, ISSN 0305-1048, pages 2809 - 2814, XP002051227 [A] 1-15 * the whole document *
 [A]  - SAKAMOTO NAOYA ET AL, "Intracellular cleavage of hepatitis C virus RNA and inhibition of viral protein translation by hammerhead ribozymes.", JOURNAL OF CLINICAL INVESTIGATION, (1996), vol. 98, no. 12, ISSN 0021-9738, pages 2720 - 2728, XP002212525 [A] 1-15 * the whole document *

DOI:   http://dx.doi.org/10.1172/JCI119097
International search[A]US5670361  (WONG-STAAL FLOSSIE [US], et al);
 [A]  - HIROAKI KAWASAKI ET AL, "Distinct roles of the co-activators p300 and CBP in retinoic-acid-induced F9-cell differentiation", NATURE, (19980521), vol. 393, no. 6682, pages 284 - 289, XP002925179

DOI:   http://dx.doi.org/10.1038/30538
 [A]  - HIROAKI KAWASAKI ET AL, "Selection of the best target site for ribozyme-mediated cleavage within a fusion gene for adenovirus E1A-associated 300kDa protein (p300) and luciferase", NUCLEIC ACIDS RESEARCH, (1996), vol. 24, no. 15, pages 3010 - 3016, XP002925180

DOI:   http://dx.doi.org/10.1093/nar/24.15.3010
The EPO accepts no responsibility for the accuracy of data originating from other authorities; in particular, it does not guarantee that it is complete, up to date or fit for specific purposes.