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Extract from the Register of European Patents

EP About this file: EP1107746

EP1107746 - METHODS OF USING AND COMPOSITIONS COMPRISING DOPAMINE REUPTAKE INHIBITORS [Right-click to bookmark this link]
StatusNo opposition filed within time limit
Status updated on  19.08.2005
Database last updated on 20.09.2024
Most recent event   Tooltip19.08.2005No opposition filed within time limitpublished on 05.10.2005  [2005/40]
Applicant(s)For all designated states
Sepracor Inc.
84 Waterford Drive
Marlborough, Massachusetts 01752 / US
[2002/51]
Former [2001/25]For all designated states
Sepracor Inc.
111 Locke Drive
Marlborough, MA 01752 / US
Inventor(s)01 / JERUSSI, Thomas, P.
19 Garvey Road
Framingham, MA 01701 / US
02 / SENANAYAKE, Chrisantha, H.
11 Old Farm Circle
Shrewbury, MA 01545 / US
03 / FANG, Qun, K.
35 Atwood Street
Wellesley, MA 02181 / US
 [2001/25]
Representative(s)Gill, Siân Victoria, et al
Venner Shipley LLP
200 Aldersgate
London EC1A 4HD / GB
[N/P]
Former [2001/25]Hughes, Siân Victoria, et al
Venner, Shipley & Co 20 Little Britain
London EC1A 7DH / GB
Application number, filing date99945137.023.08.1999
[2001/25]
WO1999US19167
Priority number, dateUS19980097665P24.08.1998         Original published format: US 97665 P
US19980099306P02.09.1998         Original published format: US 99306 P
US1999037215811.08.1999         Original published format: US 372158
[2001/36]
Former [2001/25]US19980097665P24.08.1998
US19980099306P02.09.1998
US1999037215823.08.1999
Filing languageEN
Procedural languageEN
PublicationType: A2 Application without search report
No.:WO0010551
Date:02.03.2000
Language:EN
[2000/09]
Type: A2 Application without search report 
No.:EP1107746
Date:20.06.2001
Language:EN
The application published by WIPO in one of the EPO official languages on 02.03.2000 takes the place of the publication of the European patent application.
[2001/25]
Type: B1 Patent specification 
No.:EP1107746
Date:13.10.2004
Language:EN
[2004/42]
Search report(s)International search report - published on:EP21.09.2000
ClassificationIPC:A61K31/13, A61K31/135, A61P25/28
[2004/17]
CPC:
A61K45/06 (EP,US); A61K31/135 (EP,KR,US); A61K31/11 (EP,US);
A61K31/137 (EP,US); A61P1/00 (EP); A61P1/08 (EP);
A61P15/10 (EP); A61P25/00 (EP); A61P25/06 (EP);
A61P25/08 (EP); A61P25/16 (EP); A61P25/18 (EP);
A61P25/22 (EP); A61P25/28 (EP); A61P25/30 (EP);
A61P3/04 (EP); A61P39/00 (EP); A61P43/00 (EP) (-)
C-Set:
A61K31/11, A61K2300/00 (US,EP);
A61K31/135, A61K2300/00 (US,EP);
A61K31/137, A61K2300/00 (US,EP);
A61K45/06, A61K31/135 (EP,US)
Former IPC [2001/25]A61K31/13, A61K31/135
Designated contracting statesAT,   BE,   CH,   CY,   DE,   DK,   ES,   FI,   FR,   GB,   GR,   IE,   IT,   LI,   LU,   MC,   NL,   PT,   SE [2001/25]
Extension statesAL28.02.2001
LT28.02.2001
LV28.02.2001
MK28.02.2001
RO28.02.2001
SI28.02.2001
TitleGerman:VERWENDUNGSMETHODEN UND ZUSAMMENSTELLUNGEN DIE EINEN DOPAMINEWIEDERAUFNAHMEINHIBITOR ENTHALTEN[2001/25]
English:METHODS OF USING AND COMPOSITIONS COMPRISING DOPAMINE REUPTAKE INHIBITORS[2001/25]
French:PROCEDES D'UTILISATION D'INHIBITEURS DE RECAPTAGE DE LA DOPAMINE ET COMPOSITIONS CONTENANT CES DERNIERS[2001/25]
Entry into regional phase28.02.2001National basic fee paid 
28.02.2001Designation fee(s) paid 
28.02.2001Examination fee paid 
Examination procedure22.03.2000Request for preliminary examination filed
International Preliminary Examining Authority: EP
28.02.2001Examination requested  [2001/25]
24.04.2001Amendment by applicant (claims and/or description)
22.02.2002Despatch of a communication from the examining division (Time limit: M08)
09.12.2002Despatch of communication that the application is deemed to be withdrawn, reason: reply to the communication from the examining division not received in time
18.02.2003Reply to a communication from the examining division
18.12.2003Despatch of a communication from the examining division (Time limit: M04)
23.02.2004Reply to a communication from the examining division
29.03.2004Communication of intention to grant the patent
03.07.2004Fee for grant paid
03.07.2004Fee for publishing/printing paid
Divisional application(s)EP04018454.1  / EP1475086
Opposition(s)14.07.2005No opposition filed within time limit [2005/40]
Request for further processing for:18.02.2003Request for further processing filed
18.02.2003Full payment received (date of receipt of payment)
Request granted
04.03.2002Decision despatched
Fees paidRenewal fee
14.08.2001Renewal fee patent year 03
14.08.2002Renewal fee patent year 04
28.08.2003Renewal fee patent year 05
12.08.2004Renewal fee patent year 06
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Cited inInternational search[X]DE3212682  (BOOTS CO LTD [GB]) [X] 1-7,20-24,27,29,44,59-66,75-77 * abstract * * page 18, paragraph 1; claims 44-46 * * page 24, paragraph 1; examples 1C,4K, *;
 [X]WO8806444  (BOOTS CO PLC [GB]) [X] 1-7,27-30,59-69,72-77 * abstract * * page 1, line 1 - page 3, line 3; claims 1-8 *;
 [A]US4939175  (UKAI KIYOHARU [JP], et al) [A] 1-7,27-30,59-69,72-77 * the whole document *;
 [Y]WO9400047  (SEPRACOR INC [US]) [Y] 20-24,27-29,44 * abstract * * page 2, paragraph 2 *;
 [X]WO9521615  (BOOTS CO PLC [GB], et al) [X] 1-7,27-29,59-67 * abstract * * page 3, line 24 - page 4, line 24 * * page 20, paragraph 3 *;
 [X]EP0781561  (FUJISAWA PHARMACEUTICAL CO [JP]) [X] 8,14-16* page 2, line 36 - page 3, line 27; claims 1-3 *;
 [X]WO9813034  (KNOLL AG [DE], et al) [X] 1-7,25,26,42,43,49,50,57,59-69,72-77 * abstract *;
 [PX]WO9933450  (KNOLL AG [DE], et al) [PX] 1-7,25,26,42,43,49,50,57,59-69,72-77 * abstract * * page 2, lines 1-10 *;
 [X]  - LUSCOMBE G P ET AL, "THE CONTRIBUTION OF METABOLITES TO THE RAPID AND POTENT DOWN-REGULATION OF RAT CORTICAL BETA-ADRENOCEPTORS BY THE PUTATIVE ANTIDEPRESSANT SIBUTRAMINE HYDROCHLORIDE", NEUROPHARMACOLOGY,GB,PERGAMON PRESS, OXFORD, (19890201), vol. 28, no. 2, ISSN 0028-3908, pages 129 - 134, XP000613753 [X] 1-7,20-24,27,29,44,59-66,75-77 * abstract *

DOI:   http://dx.doi.org/10.1016/0028-3908(89)90048-8
 [X]  - HEAL, D. J. ET AL, "A comparison of the effects on central 5-HT function of sibutramine hydrochloride and other weight-modifying agents", BR. J. PHARMACOL. (1998), 125(2), 301-308, XP000905054 [X] 1-7,25,26,42,43,49,50,57,59-69,72-77 * abstract *

DOI:   http://dx.doi.org/10.1038/sj.bjp.0702067
 [X]  - CHEETHAM, S. C. ET AL, "[3H]Paroxetine binding in rat frontal cortex strongly correlates with [3H]5-HT uptake: effect of administration of various antidepressant treatments", NEUROPHARMACOLOGY (1993), 32(8), 737-43, XP000905163 [X] 1-7,20-24,27,29,44,59-66,75-77 * abstract *

DOI:   http://dx.doi.org/10.1016/0028-3908(93)90181-2
 [XY]  - JEFFERY, JAMES E. ET AL, "Synthesis of sibutramine, a novel cyclobutylalkylamine useful in the treatment of obesity, and its major human metabolites", J. CHEM. SOC., PERKIN TRANS. 1 (1996), (21), 2583-2589, XP002137121 [X] 1-7,25,26,42,43,49,50,57,59-69,72-77 * page 2583, column 1, paragraphs 1-3 * [Y] 20-24,27-32,44

DOI:   http://dx.doi.org/10.1039/p19960002583
 [Y]  - GRAY, A. M.; SPENCER, P. S. J.; SEWELL, R. D. E., "The involvement of the opioidergic system in the antinociceptive mechanism of action of antidepressant compounds", BR. J. PHARMACOL., (1998), vol. 124, no. 4, pages 669 - 674, XP000909217 [Y] 30-32 * abstract *

DOI:   http://dx.doi.org/10.1038/sj.bjp.0701882
Examination   - STOCK M.J., "Sibutramine: a review of the pharmacology of a novel anti-obesity agent", INTERNATIONAL JOURNAL OF OBESITY, (1997), vol. 21, no. SP.1, pages S25 - S29
The EPO accepts no responsibility for the accuracy of data originating from other authorities; in particular, it does not guarantee that it is complete, up to date or fit for specific purposes.