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Extract from the Register of European Patents

EP About this file: EP1117658

EP1117658 - 1,3-BENZODIAZEPINES WITH INTEGRIN INHIBITORY ACTIVITY FOR USE IN THE TREATMENT OF INFLAMMATORY DISORDERS [Right-click to bookmark this link]
StatusThe application is deemed to be withdrawn
Status updated on  13.05.2005
Database last updated on 29.10.2024
Most recent event   Tooltip13.05.2005Application deemed to be withdrawnpublished on 29.06.2005  [2005/26]
Applicant(s)For all designated states
CELLTECH THERAPEUTICS LIMITED
208 Bath Road Slough
Berkshire SL1 3WE / GB
[N/P]
Former [2001/30]For all designated states
CELLTECH THERAPEUTICS LIMITED
216 Bath Road
Slough, Berkshire SL1 4EN / GB
Inventor(s)01 / BROWN, Julien, Alistair
19 Blackthorn Close, Earley
Reading, Berkshire RG6 1DH / GB
02 / WARRELLOW, Graham, John
Oakside, 4 Wieland Road
Northwood, Middlesex HA6 3QU / GB
03 / PORTER, John, Robert
5 Farm Place, Henton
Chinnor, Oxfordshire OX9 4AD / GB
04 / ARCHIBALD, Sarah, Catherine
5 College Glen
Maidenhead, Berkshire SL6 6BL / GB
05 / HEAD, John, Clifford
4 Dorchester Close
Maidenhead, Berkshire SL6 6RX / GB
 [2001/30]
Representative(s)Mercer, Christopher Paul, et al
Carpmaels & Ransford LLP
One Southampton Row
London
WC1B 5HA / GB
[N/P]
Former [2001/30]Mercer, Christopher Paul, et al
Carpmaels & Ransford 43, Bloomsbury Square
London WC1A 2RA / GB
Application number, filing date99947704.530.09.1999
[2001/30]
WO1999GB03239
Priority number, dateGB1998002122230.09.1998         Original published format: GB 9821222
[2001/30]
Filing languageEN
Procedural languageEN
PublicationType: A1 Application with search report
No.:WO0018760
Date:06.04.2000
Language:EN
[2000/14]
Type: A1 Application with search report 
No.:EP1117658
Date:25.07.2001
Language:EN
The application published by WIPO in one of the EPO official languages on 06.04.2000 takes the place of the publication of the European patent application.
[2001/30]
Search report(s)International search report - published on:EP06.04.2000
ClassificationIPC:C07D401/12, A61K31/435, A61K31/4427
[2001/30]
CPC:
C07D401/14 (EP,US); A61P1/00 (EP); A61P11/06 (EP);
A61P17/00 (EP); A61P17/06 (EP); A61P19/02 (EP);
A61P25/00 (EP); A61P29/00 (EP); A61P3/10 (EP);
A61P37/02 (EP); A61P37/06 (EP); A61P43/00 (EP) (-)
Designated contracting statesAT,   BE,   CH,   CY,   DE,   DK,   ES,   FI,   FR,   GB,   GR,   IE,   IT,   LI,   LU,   MC,   NL,   PT,   SE [2001/30]
Extension statesALNot yet paid
LTNot yet paid
LVNot yet paid
MKNot yet paid
RONot yet paid
SINot yet paid
TitleGerman:1,3-BENZODIAZEPINE MIT INTEGRIN INHIBIERENDER WIRKUNG ZUR VERWENDUNG BEI DER BEHANDLUNG ENTZÜNDLICHER PROZESSE[2001/30]
English:1,3-BENZODIAZEPINES WITH INTEGRIN INHIBITORY ACTIVITY FOR USE IN THE TREATMENT OF INFLAMMATORY DISORDERS[2001/30]
French:1,3-BENZODIAZEPINES POSSEDANT UNE ACTIVITE INHIBANT L'INTEGRINE UTILES POUR TRAITER DES TROUBLES INFLAMMATOIRES[2001/30]
Entry into regional phase19.04.2001National basic fee paid 
19.04.2001Designation fee(s) paid 
19.04.2001Examination fee paid 
Examination procedure26.04.2000Request for preliminary examination filed
International Preliminary Examining Authority: EP
19.04.2001Examination requested  [2001/30]
09.07.2003Despatch of a communication from the examining division (Time limit: M04)
13.11.2003Reply to a communication from the examining division
10.02.2004Despatch of a communication from the examining division (Time limit: M04)
04.06.2004Reply to a communication from the examining division
13.08.2004Communication of intention to grant the patent
24.12.2004Application deemed to be withdrawn, date of legal effect  [2005/26]
31.01.2005Despatch of communication that the application is deemed to be withdrawn, reason: fee for grant / fee for printing not paid in time  [2005/26]
Fees paidRenewal fee
19.04.2001Renewal fee patent year 03
12.09.2002Renewal fee patent year 04
12.09.2003Renewal fee patent year 05
14.09.2004Renewal fee patent year 06
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Cited inInternational search[A]WO9300095  (SMITHKLINE BEECHAM CORP [US]) [A] 1-8 * column W *;
 [A]WO9308174  (GENENTECH INC [US]) [A] 1-8 * column W *;
 [A]WO9626190  (SMITHKLINE BEECHAM CORP [US], et al) [A] 1-8 * column W *;
 [A]  - VENTURELLA,V.S. ET AL., "Substituted 1,3-dihydro-4H-furo[3,4-d]-1,3-benzodiazepin-3-ones : Synthesis and scope of method", J.HETEROCYCLIC.CHEM., ALBUQUERQUE, (1969), vol. 6, no. 5, pages 671 - 679, XP002128238 [A] 1-8 * column W *

DOI:   http://dx.doi.org/10.1002/jhet.5570060514
 [A]  - MILLER W H ET AL, "Structure-activity relationships in 3-oxo-1,4-benzodiazepine-2-acetic acid GPIIb/IIIa antagonists. The 2-benzazepine series", BIOORGANIC & MEDICINAL CHEMISTRY LETTERS,GB,OXFORD, (1996), vol. 6, no. 21, ISSN 0960-894X, page 2481-2486, XP004135899 [A] 1-8 * column W *

DOI:   http://dx.doi.org/10.1016/0960-894X(96)00432-5
 [A]  - MCDOWELL R S ET AL, "FROM PEPTIDE TO NON-PEPTIDE. THE DE NOVO DESIGN OF POTENT, NON- PEPTIDAL INHIBITORS OF PLATELET AGGREGATION BASED ON A BENZODIAZEPINEDIONE SCAFFOLD", JOURNAL OF THE AMERICAN CHEMICAL SOCIETY,US,AMERICAN CHEMICAL SOCIETY, WASHINGTON, DC, (1994), vol. 116, no. 12, ISSN 0002-7863, page 5077-5083, XP002069808 [A] 1-8 * column W *

DOI:   http://dx.doi.org/10.1021/ja00091a008
 [A]  - KEENAN,R.M. ET AL., "Discovery of Potent Nonpeptide Vitronectin Receptor Antagonists", J.MED.CHEM., WASHINGTON, (19970718), vol. 40, no. 15, pages 2289 - 2292, XP002128454 [A] 1-8 * column W *

DOI:   http://dx.doi.org/10.1021/jm970205r
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