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Extract from the Register of European Patents

EP About this file: EP1117437

EP1117437 - USE OF COMPOUNDS THAT REDUCE ALPHA2-ANTIPLASMIN IN VIVO FOR THE PREPARATION OF A COMPOSITION FOR THE TREATMENT OF ISCHEMIC STROKE [Right-click to bookmark this link]
StatusNo opposition filed within time limit
Status updated on  02.11.2007
Database last updated on 05.10.2024
Most recent event   Tooltip08.01.2010Lapse of the patent in a contracting state
New state(s): CY, LU
published on 10.02.2010  [2010/06]
Applicant(s)For all designated states
Leuven Research & Development vzw
Benedenstraat 60
B-3000 Leuven / BE
[2006/52]
Former [2004/21]For all designated states
Leuven Research & Development VZW
Benedenstraat 60
B-3000 Leuven / BE
Former [2001/30]For all designated states
K.U. Leuven Research & Development
Groot Begijnhof, Benedenstraat 60
3000 Leuven / BE
Inventor(s)01 / NAGAI, Nobuo
E-317, Handa-cho 3776
Hamamatsu, Shizuoka 431-3124 / JP
02 / COLLEN, Désiré, José
28 Collingham Gardens
London SW5 0HN / GB
 [2001/30]
Representative(s)van Someren, Petronella F. H. M., et al
Arnold & Siedsma
Bezuidenhoutseweg 57
2594 AC The Hague / NL
[N/P]
Former [2008/34]Van Someren, Petronella F. H. M., et al
Arnold & Siedsma, Sweelinkplein 1
2517 GK The Hague / NL
Former [2001/30]Van Someren, Petronella F. H. M., et al
Arnold & Siedsma, Advocaten en Octrooigemachtigden, Sweelinckplein 1
2517 GK Den Haag / NL
Application number, filing date99948942.024.09.1999
[2001/30]
WO1999EP07405
Priority number, dateEP1998020328029.09.1998         Original published format: EP 98203280
EP1999020200422.06.1999         Original published format: EP 99202004
[2001/30]
Filing languageEN
Procedural languageEN
PublicationType: A1 Application with search report
No.:WO0018436
Date:06.04.2000
Language:EN
[2000/14]
Type: A1 Application with search report 
No.:EP1117437
Date:25.07.2001
Language:EN
The application published by WIPO in one of the EPO official languages on 06.04.2000 takes the place of the publication of the European patent application.
[2001/30]
Type: B1 Patent specification 
No.:EP1117437
Date:27.12.2006
Language:EN
[2006/52]
Search report(s)International search report - published on:EP06.04.2000
ClassificationIPC:A61K39/395, A61K38/48, A61P9/10
[2001/30]
CPC:
A61K38/484 (EP,US); A61P7/02 (EP); A61P9/08 (EP);
A61P9/10 (EP); C07K16/38 (EP,US)
Designated contracting statesAT,   BE,   CH,   CY,   DE,   DK,   ES,   FI,   FR,   GB,   GR,   IE,   IT,   LI,   LU,   MC,   NL,   PT,   SE [2001/30]
Extension statesALNot yet paid
LTNot yet paid
LVNot yet paid
MKNot yet paid
RONot yet paid
SINot yet paid
TitleGerman:VERWENDUNG VON VERBINDUNGEN DIE ALPHA2-ANTIPLASMIN IN VIVO REDUZIEREN ZUR HERSTELLUNG EINER ZUSAMMENSETZUNG ZUR BEHANDLUNG ISCHÄMISCHER SCHLAGANFÄLLE[2001/30]
English:USE OF COMPOUNDS THAT REDUCE ALPHA2-ANTIPLASMIN IN VIVO FOR THE PREPARATION OF A COMPOSITION FOR THE TREATMENT OF ISCHEMIC STROKE[2001/30]
French:UTILISATION DE COMPOSES DE REDUCTION DES $g(a) 2?-ANTIPLASMINES IN-VIVO POUR LA PREPARATION D'UNE COMPOSITION THERAPEUTIQUE CONTRE L'ACCIDENT ISCHEMIQUE CEREBRAL[2001/30]
Entry into regional phase18.04.2001National basic fee paid 
18.04.2001Designation fee(s) paid 
18.04.2001Examination fee paid 
Examination procedure27.04.2000Request for preliminary examination filed
International Preliminary Examining Authority: EP
18.04.2001Examination requested  [2001/30]
24.08.2004Despatch of a communication from the examining division (Time limit: M06)
01.03.2005Reply to a communication from the examining division
14.04.2005Despatch of a communication from the examining division (Time limit: M06)
29.09.2005Reply to a communication from the examining division
07.04.2006Cancellation of oral proceeding that was planned for 10.04.2006
07.04.2006Minutes of oral proceedings despatched
10.04.2006Date of oral proceedings (cancelled)
08.05.2006Communication of intention to grant the patent
22.06.2006Fee for grant paid
22.06.2006Fee for publishing/printing paid
Opposition(s)28.09.2007No opposition filed within time limit [2007/49]
Fees paidRenewal fee
27.09.2001Renewal fee patent year 03
27.09.2002Renewal fee patent year 04
30.09.2003Renewal fee patent year 05
28.09.2004Renewal fee patent year 06
29.09.2005Renewal fee patent year 07
27.09.2006Renewal fee patent year 08
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Lapses during opposition  TooltipAT27.12.2006
CY27.12.2006
NL27.12.2006
GR28.03.2007
PT28.05.2007
LU24.09.2007
[2010/06]
Former [2008/21]AT27.12.2006
NL27.12.2006
GR28.03.2007
PT28.05.2007
Former [2008/18]AT27.12.2006
NL27.12.2006
PT28.05.2007
Former [2007/31]AT27.12.2006
Cited inInternational search[X]EP0631786  (IMMUNO AG [AT]) [X] 6 * claim - *;
 [X]WO9812329  (REED GUY L [US]) [X] 1-6 * page 23, line 25 - page 24, line 9 * * examples 1,2 * * claim - *;
 [A]  - A. BUTTE ET AL., "Alpha2-antiplasmin causes thrombi to resist fibrinolysis induced by tissue plasminogen activator in experimental pulmonary embolism.", CIRCULATION, New York, NY, USA, (19970401), vol. 95, no. 7, pages 1886 - 1891, XP002062707 [A] 1-5 * the whole document *
 [A]  - G. REED, "Functional characterization of monoclonal antibody inhibitors of alpha2-antiplasmin that accelerate fibrinolysis in different animal plasmas.", HYBRIDOMA, New York, NY, USA, (199706), vol. 16, no. 3, pages 281 - 286, XP002062706 [A] 1-5 * abstract *
 [PX]  - N. NAGAI ET AL., "Role of plasminogen system components in focal cerebral ischemic infarction: a gene targeting and gene transfer study in mice.", CIRCULATION, New York, NY, USA, (19990511), vol. 99, no. 18, pages 2440 - 2444, XP002112003 [PX] 1-5 * the whole document *
The EPO accepts no responsibility for the accuracy of data originating from other authorities; in particular, it does not guarantee that it is complete, up to date or fit for specific purposes.