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Extract from the Register of European Patents

EP About this file: EP1117428

EP1117428 - COMPOSITIONS AND THEIR USE FOR INHIBITING ANGIOGENESIS [Right-click to bookmark this link]
Former [2001/30]COMPOSITIONS AND METHODS FOR INHIBITING ANGIOGENESIS
[2003/18]
StatusNo opposition filed within time limit
Status updated on  30.07.2004
Database last updated on 31.08.2024
Most recent event   Tooltip28.03.2008Lapse of the patent in a contracting state
New state(s): IT, PT		published on 30.04.2008  [2008/18]
Applicant(s)For all designated states
CHILDREN'S HOSPITAL
300 Longwood Avenue
Boston, MA 02115 / US
[2001/30]
Inventor(s)01 / O'REILLY, Michael, S.
336 Main Street
Winchester, MA 01890 / US
02 / PIRIE-SHEPHERD, Steven
81 Trapelo Road, 58
Waltham, MA 02542 / US
03 / FOLKMAN, M., Judah
18 Chatham Circle
Brookline, MA 02115 / US
 [2001/30]
Representative(s)Hoffmann Eitle
Patent- und Rechtsanwälte PartmbB
Arabellastrasse 30
81925 München / DE
[N/P]
Former [2001/30]HOFFMANN - EITLE
Patent- und Rechtsanwälte Arabellastrasse 4
81925 München / DE
Application number, filing date99954789.608.10.1999
[2001/30]
WO1999US23450
Priority number, dateUS19980103526P08.10.1998         Original published format: US 103526 P
US19990116131P15.01.1999         Original published format: US 116131 P
[2001/30]
Filing languageEN
Procedural languageEN
PublicationType: A2 Application without search report
No.:WO0020026
Date:13.04.2000
Language:EN
[2000/15]
Type: A2 Application without search report 
No.:EP1117428
Date:25.07.2001
Language:EN
The application published by WIPO in one of the EPO official languages on 13.04.2000 takes the place of the publication of the European patent application.
[2001/30]
Type: B1 Patent specification 
No.:EP1117428
Date:24.09.2003
Language:EN
[2003/39]
Search report(s)International search report - published on:EP08.09.2000
ClassificationIPC:A61K38/55, A61K38/57, G01N33/68, C12Q1/02, A61P35/00, A61P9/00, A61P17/06, A61P27/00, // A61K48:00
[2001/30]
CPC:
G01N33/5088 (EP,US); A61K38/57 (EP,US); A61P17/06 (EP);
A61P27/00 (EP); A61P35/00 (EP); A61P43/00 (EP);
A61P9/00 (EP); G01N33/5011 (EP,US); G01N33/5091 (EP,US);
A61K48/00 (EP,US); G01N2500/00 (EP,US) (-)
Designated contracting statesAT,   BE,   CH,   CY,   DE,   DK,   ES,   FI,   FR,   GB,   GR,   IE,   IT,   LI,   LU,   MC,   NL,   PT,   SE [2001/30]
Extension statesALNot yet paid
LTNot yet paid
LVNot yet paid
MKNot yet paid
RONot yet paid
SINot yet paid
TitleGerman:ZUSAMMENSETZUNGEN UND DEREN VERWENDUNG ZUR HEMMUNG VON ANGIOGENESE[2003/18]
English:COMPOSITIONS AND THEIR USE FOR INHIBITING ANGIOGENESIS[2003/18]
French:COMPOSITIONS ET LEUR UTILISATION POUR INHIBER L'ANGIOGENESE[2003/18]
Former [2001/30]ZUSAMMENSETZUNGEN UND METHODEN ZUR HEMMUNG VON ANGIOGENESE
Former [2001/30]COMPOSITIONS AND METHODS FOR INHIBITING ANGIOGENESIS
Former [2001/30]COMPOSITIONS ET METHODES PERMETTANT D'INHIBER L'ANGIOGENESE
Entry into regional phase25.04.2001National basic fee paid 
25.04.2001Designation fee(s) paid 
25.04.2001Examination fee paid 
Examination procedure05.05.2000Request for preliminary examination filed
International Preliminary Examining Authority: EP
25.04.2001Amendment by applicant (claims and/or description)
25.04.2001Examination requested  [2001/30]
04.09.2001Despatch of a communication from the examining division (Time limit: M06)
04.03.2002Reply to a communication from the examining division
02.05.2002Despatch of a communication from the examining division (Time limit: M04)
03.09.2002Reply to a communication from the examining division
04.11.2002Despatch of a communication from the examining division (Time limit: M04)
09.01.2003Reply to a communication from the examining division
10.04.2003Communication of intention to grant the patent
30.07.2003Fee for grant paid
30.07.2003Fee for publishing/printing paid
Opposition(s)25.06.2004No opposition filed within time limit [2004/38]
Fees paidRenewal fee
22.10.2001Renewal fee patent year 03
21.10.2002Renewal fee patent year 04
Opt-out from the exclusive  Tooltip
competence of the Unified
Patent Court		 See the Register of the Unified Patent Court for opt-out data
Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court.
Lapses during opposition  TooltipAT24.09.2003
BE24.09.2003
CH24.09.2003
FI24.09.2003
FR24.09.2003
IT24.09.2003
LI24.09.2003
NL24.09.2003
CY08.10.2003
IE08.10.2003
LU08.10.2003
MC31.10.2003
DK24.12.2003
GB24.12.2003
GR24.12.2003
SE24.12.2003
DE25.12.2003
ES04.01.2004
PT24.02.2004
[2008/18]
Former [2006/14]AT24.09.2003
BE24.09.2003
CH24.09.2003
FI24.09.2003
FR24.09.2003
LI24.09.2003
NL24.09.2003
CY08.10.2003
IE08.10.2003
LU08.10.2003
MC31.10.2003
DK24.12.2003
GB24.12.2003
GR24.12.2003
SE24.12.2003
DE25.12.2003
ES04.01.2004
Former [2005/03]AT24.09.2003
BE24.09.2003
CH24.09.2003
FI24.09.2003
LI24.09.2003
NL24.09.2003
CY08.10.2003
IE08.10.2003
LU08.10.2003
MC31.10.2003
DK24.12.2003
GB24.12.2003
GR24.12.2003
SE24.12.2003
DE25.12.2003
ES04.01.2004
Former [2005/02]AT24.09.2003
BE24.09.2003
CH24.09.2003
FI24.09.2003
LI24.09.2003
NL24.09.2003
CY08.10.2003
LU08.10.2003
MC31.10.2003
DK24.12.2003
GB24.12.2003
GR24.12.2003
SE24.12.2003
DE25.12.2003
ES04.01.2004
Former [2005/01]AT24.09.2003
BE24.09.2003
CH24.09.2003
FI24.09.2003
LI24.09.2003
NL24.09.2003
CY08.10.2003
LU08.10.2003
DK24.12.2003
GB24.12.2003
GR24.12.2003
SE24.12.2003
DE25.12.2003
ES04.01.2004
Former [2004/46]AT24.09.2003
BE24.09.2003
CH24.09.2003
FI24.09.2003
LI24.09.2003
NL24.09.2003
CY08.10.2003
LU08.10.2003
DK24.12.2003
GR24.12.2003
SE24.12.2003
DE25.12.2003
ES04.01.2004
Former [2004/44]AT24.09.2003
BE24.09.2003
CH24.09.2003
FI24.09.2003
LI24.09.2003
NL24.09.2003
CY08.10.2003
LU08.10.2003
DK24.12.2003
GR24.12.2003
SE24.12.2003
DE25.12.2003
Former [2004/41]AT24.09.2003
BE24.09.2003
CH24.09.2003
FI24.09.2003
LI24.09.2003
NL24.09.2003
CY08.10.2003
LU08.10.2003
DK24.12.2003
GR24.12.2003
SE24.12.2003
Former [2004/39]AT24.09.2003
BE24.09.2003
CH24.09.2003
FI24.09.2003
LI24.09.2003
NL24.09.2003
CY08.10.2003
LU08.10.2003
GR24.12.2003
SE24.12.2003
Former [2004/36]AT24.09.2003
BE24.09.2003
CH24.09.2003
FI24.09.2003
LI24.09.2003
NL24.09.2003
CY08.10.2003
GR24.12.2003
SE24.12.2003
Former [2004/33]AT24.09.2003
BE24.09.2003
CH24.09.2003
FI24.09.2003
LI24.09.2003
NL24.09.2003
GR24.12.2003
SE24.12.2003
Former [2004/28]AT24.09.2003
BE24.09.2003
FI24.09.2003
GR24.12.2003
SE24.12.2003
Former [2004/16]AT24.09.2003
FI24.09.2003
GR24.12.2003
SE24.12.2003
Former [2004/14]AT24.09.2003
FI24.09.2003
GR24.12.2003
Former [2004/12]FI24.09.2003
Cited inInternational search[X]US5151509  (KOTWAL GIRISH J [US], et al) [X] 15,16,18-20 * column 2, line 35 - line 45; figures 3A1-3A11,3B1-3B10 * * column 1, line 55 - line 62 * * column 1, line 15 - line 27 *;
 [PA]WO9908522  (LUDWIG INST CANCER RES [US], et al) [PA] 1-40 * page 31, claim 19; page 32, claim 20;; page 7, line 4 - line 18; example 16 *;
 [A]  - G.A. SOFF ET AL., "PAI-1 EXPRESSION HUMAN PROSTATE CARCINOMA CELLS INHIBITS PRIMARY TUMOR GROWTH, TUMOR-ASSOCIATED ANGIOGENESIS AND METASTASES IN AN ATHYMIC MOUSE CARCINOMA MODEL.", PROCEEDINGS OF THE EIGHTY-SIXTH ANNUAL MEETING OF THE AMERICAN ASSOCIATION FOR CANCER RESEARCH, MARCH 18-22, 1995, TORONTO, CANADA, (199503), vol. 36, page 101, XP002135981 [A] 1-40 * abstract nr. 602 *
 [A]  - TSOPANOGLOU NIKOS E ET AL, "Thrombin promotes angiogenesis by a mechanism independent of fibrin formation.", BIOSIS, BIOSCIENCES INFORMATION SERVICE, PHILADELPHIA, PA, US, (1993), Database accession no. PREV199396037222, XP002135984 [A] 1-40 * abstract *
    [ ] - AMERICAN JOURNAL OF PHYSIOLOGY 1993, (1993), vol. 264, no. 5 PART 1, ISSN 0002-9513, pages C1302 - C1307
 [PX]  - M.S. O'REILLY ET AL., "ANTIANGIOGENIC ACTIVITY OF THE CLEAVED CONFORMATION OF THE SERPIN ANTITHROMBIN.", SCIENCE, LANCASTER, PA, US, (19990917), vol. 285, pages 1926 - 1928, XP002135982 [PX] 1-4,6-11,13-18,20,21,29-31,33-36,38-40 * the whole document *

DOI:   http://dx.doi.org/10.1126/science.285.5435.1926
 [PX]  - D.W. DAWSON ET AL., "PIGMENT EPITHELIUM-DERIVED FACTOR: A POTENT INHIBITOR OF ANGIOGENESIS.", SCIENCE, LANCASTER, PA, US, (19990709), vol. 285, pages 245 - 248, XP002135983 [PX] 1,2,4,5,8,9,11,12,15,16,18,19,29,31,32,34,36,37 * the whole document *

DOI:   http://dx.doi.org/10.1126/science.285.5425.245
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