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Extract from the Register of European Patents

EP About this file: EP1119252

EP1119252 - USE OF MELANIN FOR INHIBITION OF ANGIOGENESIS AND MACULAR DEGENERATION [Right-click to bookmark this link]
StatusThe application has been withdrawn
Status updated on  29.10.2004
Database last updated on 11.09.2024
Most recent event   Tooltip29.10.2004Withdrawal of applicationpublished on 15.12.2004  [2004/51]
Applicant(s)For all designated states
The Children's Medical Center Corporation
300 Longwood Avenue
Boston, Massachusetts 02115 / US
[2001/31]
Inventor(s)01 / D'AMATO, Robert, J.
65 Huron Avenue
Cambridge, MA 02138 / US
 [2001/31]
Representative(s)polypatent
Postfach 40 02 43
51410 Bergisch Gladbach / DE
[N/P]
Former [2001/31]Sternagel, Fleischer, Godemeyer & Partner
Patentanwälte Braunsberger Feld 29
51429 Bergisch Gladbach / DE
Application number, filing date99967818.820.08.1999
[2001/31]
WO1999US19026
Priority number, dateUS19980097385P21.08.1998         Original published format: US 97385 P
[2001/31]
Filing languageEN
Procedural languageEN
PublicationType: A2 Application without search report
No.:WO0010507
Date:02.03.2000
Language:EN
[2000/09]
Type: A2 Application without search report 
No.:EP1119252
Date:01.08.2001
Language:EN
The application published by WIPO in one of the EPO official languages on 02.03.2000 takes the place of the publication of the European patent application.
[2001/31]
Search report(s)International search report - published on:US31.05.2001
(Supplementary) European search report - dispatched on:EP19.01.2004
ClassificationIPC:A61K31/404, A61P27/02
[2004/10]
CPC:
A61K31/00 (EP,US); A61K31/65 (EP,US); A61K31/775 (EP,US);
A61K31/787 (EP,US); A61P27/02 (EP); A61P35/00 (EP);
A61P43/00 (EP); C08F2/32 (EP,US); C08F20/28 (EP,US);
C08J2201/028 (EP,US); C08J2203/08 (EP,US); C08J2207/12 (EP,US) (-)
Former IPC [2001/31]A01N37/18
Designated contracting statesAT,   BE,   CH,   CY,   DE,   DK,   ES,   FI,   FR,   GB,   GR,   IE,   IT,   LI,   LU,   MC,   NL,   PT,   SE [2001/31]
Extension statesALNot yet paid
LTNot yet paid
LVNot yet paid
MKNot yet paid
RONot yet paid
SINot yet paid
TitleGerman:VERWENDUNG VON MELANIN ZUR HEMMUNG DER ANGIOGENESE UND MAKULÄREN DEGENERATION[2001/31]
English:USE OF MELANIN FOR INHIBITION OF ANGIOGENESIS AND MACULAR DEGENERATION[2001/31]
French:UTILISATION DE MELANINE POUR INHIBER L'ANGIOGENESE ET LA DEGENERESCENCE MACULAIRE[2001/31]
Entry into regional phase21.03.2001National basic fee paid 
21.03.2001Search fee paid 
21.03.2001Designation fee(s) paid 
21.03.2001Examination fee paid 
Examination procedure20.03.2000Request for preliminary examination filed
International Preliminary Examining Authority: US
21.03.2001Examination requested  [2001/31]
18.05.2001Amendment by applicant (claims and/or description)
21.10.2004Application withdrawn by applicant  [2004/51]
Fees paidRenewal fee
22.08.2001Renewal fee patent year 03
21.08.2002Renewal fee patent year 04
25.08.2003Renewal fee patent year 05
Penalty fee
Additional fee for renewal fee
31.08.200406   M06   Not yet paid
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Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court.
Documents cited:Search[T]WO9857647  (BAYLOR COLLEGE MEDICINE [US], et al) [T] 5-8 * claim 3 and 5 *
 [X]  - KAMEI HIDEO ET AL, "Effect of allomelanin on tumor growth suppression in vivo and on the cell cycle phase", CANCER BIOTHERAPY AND RADIOPHARMACEUTICALS, (199708), vol. 12, no. 4, ISSN 1084-9785, pages 273 - 276, XP009023397 [X] 1-3 * figure 1 *
 [X]  - WONG K T ET AL, "A cytotoxic melanin precursor, 5,6-dihydroxyindole, from the folkloric anti-cancer plant Rhaphidophora korthalsii", NATURAL PRODUCT LETTERS 1996 UNITED KINGDOM, (1996), vol. 9, no. 2, ISSN 1057-5634, pages 137 - 140, XP009023406 [X] 1-3 * page 137-138, paragraph entitled "Results and Discussion" *
 [A]  - SARNA T, "PROPERTIES AND FUNCTION OF THE OCULAR MELANIN - A PHOTOBIOPHYSICAL VIEW", JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY B: BIOLOGY, ELSEVIER SCIENCE S.A., BASEL, CH, (1992), vol. 12, no. 3, ISSN 1011-1344, pages 215 - 258, XP009012746 [A] 1-4 * page 248-249, paragraph entitled "7. Conclusions" *

DOI:   http://dx.doi.org/10.1016/1011-1344(92)85027-R
 [T]  - BEK EUGENE L ET AL, "Endothelins are angiogenic", JOURNAL OF CARDIOVASCULAR PHARMACOLOGY, (2000), vol. 36, no. 5 Supplement 1, ISSN 0160-2446, pages S135 - S139, XP009023421 [T] 5-8 * page S136, left-hand column, first full paragraph; table 2 *
International search[XP]  - BOHM ET AL., "Alpha-melanocyte-stimulating hormone modulates activation of NG-kappa B and AP-1 and secretion of interleukin-8", SCISEARCH, UNIV. MUNSTER, DEPT. DERMATOL. (MUNSTER, GERMANY), Database accession no. 2000:14320, XP002941220
    [ ] - ANNALS OF THE NEW YORK ACADEMY OF SCIENCES, (199912), vol. 885, pages 277 - 286
The EPO accepts no responsibility for the accuracy of data originating from other authorities; in particular, it does not guarantee that it is complete, up to date or fit for specific purposes.