EP1141294 - METHOD OF ENHANCING THE BIOLOGICAL ACTIVITY OF LIGANDS [Right-click to bookmark this link] | Status | No opposition filed within time limit Status updated on 06.01.2006 Database last updated on 09.05.2025 | Most recent event Tooltip | 28.03.2008 | Lapse of the patent in a contracting state New state(s): IT, SE | published on 30.04.2008 [2008/18] | Applicant(s) | For all designated states REGENERON PHARMACEUTICALS, INC. 777 Old Saw Mill River Road Tarrytown, NY 10591-6707 / US | [2001/41] | Inventor(s) | 01 /
DAVIS, Samuel, J. 332 W. 88th Street, B2 New York, NY 10024 / US | 02 /
GALE, Nicholas, W. Apartment 46V, 177 White Plains Road Tarrytown, NY 10591 / US | 03 /
YANCOPOULOS, George, D. 1519 Baptist Church Road Yorktown Heigths, NY 10598 / US | 04 /
STAHL, Neil RD 10, Kent Shore Drive Carmel, NY 10512 / US | [2004/37] |
Former [2001/41] | 01 /
DAVIS, Samuel 332 W. 88th Street, B2 New York, NY 10024 / US | ||
02 /
GALE, Nicholas, W. Apartment 46V, 177 White Plains Road Tarrytown, NY 10591 / US | |||
03 /
YANCOPOULOS, George, D. 1519 Baptist Church Road Yorktown Heigths, NY 10598 / US | |||
04 /
STAHL, Neil RD 10, Kent Shore Drive Carmel, NY 10512 / US | Representative(s) | Duckworth, Timothy John J A Kemp 14 South Square Gray's Inn London WC1R 5JJ / GB | [N/P] |
Former [2003/51] | Duckworth, Timothy John J.A. Kemp & Co., 14 South Square, Gray's Inn London WC1R 5JJ / GB | ||
Former [2001/41] | Goldin, Douglas Michael J.A. KEMP & CO. 14 South Square Gray's Inn London WC1R 5JJ / GB | Application number, filing date | 99968956.5 | 23.12.1999 | [2001/41] | WO1999US30900 | Priority number, date | US19980113387P | 23.12.1998 Original published format: US 113387 P | [2001/41] | Filing language | EN | Procedural language | EN | Publication | Type: | A1 Application with search report | No.: | WO0037642 | Date: | 29.06.2000 | Language: | EN | [2000/26] | Type: | A1 Application with search report | No.: | EP1141294 | Date: | 10.10.2001 | Language: | EN | The application published by WIPO in one of the EPO official languages on 29.06.2000 takes the place of the publication of the European patent application. | [2001/41] | Type: | B1 Patent specification | No.: | EP1141294 | Date: | 02.03.2005 | Language: | EN | [2005/09] | Search report(s) | International search report - published on: | EP | 29.06.2000 | Classification | IPC: | C12N15/62, C12N5/10, C07K14/515, C07K14/52 | [2004/31] | CPC: |
C07K14/515 (EP,US);
A61P25/28 (EP);
C07K14/52 (EP,US);
C12N15/62 (EP,US);
A61K38/00 (EP,US);
C07K2319/00 (EP,US);
C07K2319/02 (EP,US);
C07K2319/30 (EP,US);
C07K2319/73 (EP,US);
C07K2319/75 (EP,US)
(-)
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Former IPC [2001/41] | C12N15/12, C12N15/62, C12N5/10, C12N1/21, C07K14/515, C07K14/52 | Designated contracting states | AT, BE, CH, CY, DE, DK, ES, FI, FR, GB, GR, IE, IT, LI, LU, MC, NL, PT, SE [2001/41] | Extension states | AL | Not yet paid | LT | Not yet paid | LV | Not yet paid | MK | Not yet paid | RO | Not yet paid | SI | Not yet paid | Title | German: | METHODE ZUR VERSTÄRKUNG DER BIOLOGISCHEN AKTIVITÄT VON LIGANDEN | [2001/41] | English: | METHOD OF ENHANCING THE BIOLOGICAL ACTIVITY OF LIGANDS | [2001/41] | French: | TECHNIQUE PERMETTANT D'ACCROITRE L'ACTIVITE BIOLOGIQUE DE LIGANDS | [2001/41] | Entry into regional phase | 27.06.2001 | National basic fee paid | 27.06.2001 | Designation fee(s) paid | 27.06.2001 | Examination fee paid | Examination procedure | 23.06.2000 | Request for preliminary examination filed International Preliminary Examining Authority: EP | 27.06.2001 | Examination requested [2001/41] | 19.09.2003 | Despatch of a communication from the examining division (Time limit: M04) | 21.01.2004 | Reply to a communication from the examining division | 02.08.2004 | Communication of intention to grant the patent | 19.11.2004 | Fee for grant paid | 19.11.2004 | Fee for publishing/printing paid | Opposition(s) | 05.12.2005 | No opposition filed within time limit [2006/08] | Fees paid | Renewal fee | 31.12.2001 | Renewal fee patent year 03 | 23.12.2002 | Renewal fee patent year 04 | 29.12.2003 | Renewal fee patent year 05 | 23.12.2004 | Renewal fee patent year 06 |
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Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court. | Lapses during opposition Tooltip | FI | 02.03.2005 | IT | 02.03.2005 | DK | 02.06.2005 | GR | 02.06.2005 | SE | 02.06.2005 | ES | 13.06.2005 | PT | 03.08.2005 | [2008/18] |
Former [2006/14] | FI | 02.03.2005 | |
DK | 02.06.2005 | ||
GR | 02.06.2005 | ||
ES | 13.06.2005 | ||
PT | 03.08.2005 | ||
Former [2006/12] | FI | 02.03.2005 | |
DK | 02.06.2005 | ||
ES | 13.06.2005 | ||
Former [2005/46] | FI | 02.03.2005 | Cited in | International search | [XAY]WO9203569 (SANGSTAT MEDICAL CORP [US]) [X] 23-26,29,32-41 * abstract * * page 1 - page 3 * * page 19, line 14 - line 23 * [A] 27,28 [Y] 30; | [YD]WO9527060 (REGENERON PHARMA [US]) [YD] 8-11,30 * abstract * * page 23, line 21 - page 24, line 8 * * claims 4,8 *; | [XAY]WO9637621 (MORPHOSYS PROTEINOPTIMIERUNG [DE], et al) [X] 1-5,12-22 * abstract * * page 1, line 12 - line 15 * * page 2, line 4 - line 9 * * page 14, line 6 - line 11 * * page 16, line 29 - line 34 * * figure 1A * [A] 6,7 [Y] 8-11; | [A]EP0816510 (TORAY INDUSTRIES [JP], et al) [A] 1-22 * abstract *; | [AD] - DAVIS S. ET AL., "Isolation of Angiopoietin-1, a ligand for the TIE2 receptor, by secretion-trap expression cloning", CELL, (19961227), vol. 87, pages 1161 - 1169, XP002138354 [AD] 6,7,27,28 * the whole document * DOI: http://dx.doi.org/10.1016/S0092-8674(00)81812-7 | [AD] - MAISONPIERRE P.C. ET AL., "Angiopoietin-2, a natural antagonist for Tie2 that disrupts in vivo angiogenesis.", SCIENCE, (19970704), vol. 277, pages 55 - 60, XP002138355 [AD] 6,7,27,28 * the whole document * DOI: http://dx.doi.org/10.1126/science.277.5322.55 | [A] - TOURNAY C. ET AL., "Uptake of recombinant myeloperoxidase, free or fused to Fc-gamma, by macrophages enhances killing activity towards micro-organisms", DNA CELL BIOLOGY, (1996), vol. 15, no. 8, pages 617 - 624, XP000907279 [A] 21,40 * abstract * * page 618 * |