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Extract from the Register of European Patents

EP About this file: EP1255852

EP1255852 - IMMUNOASSAY AND DIAGNOSTIC REAGENT FOR MALARIA [Right-click to bookmark this link]
StatusNo opposition filed within time limit
Status updated on  16.10.2009
Database last updated on 18.05.2024
Most recent event   Tooltip30.09.2011Lapse of the patent in a contracting state
New state(s): CY, TR		published on 02.11.2011  [2011/44]
Applicant(s)For all designated states
LG Chem Investment, Ltd
20, Yoido-dong Yongdungpo-ku
Seoul 150-721 / KR
[2008/28]
Former [2002/46]For all designated states
LG Chem Investment, Ltd
LG Twin Towers, 20, Youido-dong, Yongdungpo-ku
Seoul 150-721 / KR
Inventor(s)01 / LIM, Kook-Jin
Eunbitmaeul 521-1807, 870 Hwajong-dong, Deokyang-ku
Koyang-si, Kyungki-do 412-270 / KR
02 / SHON, Mi-Jin
Hanbit Apt. 125-505, 99 Eoeun-dong, Yoosung-ku
Daejeon-si 305-755 / KR
03 / YOO, Seung-Bum
Hanuri Apt. 104-601, 763, Tanbang-dong, Seo-ku
Daejeon-si 302-768 / KR
04 / LEE, Sang-Ik
Narae Apt. 104-1303, 462-4 Jeonmin-dong, Yoosung-ku
Daejeon-si 305-811 / KR
05 / OH, Jae-Hoon
Chungsol Apt. 102-306, 8-2 Songang-dong, Yoosung-ku
Daejeon-si 305-752 / KR
06 / LEE, Seung-Won
Limaechon 206-1804, 124, Limae-dong, Bundang-ku
Sungnam-si, Kyungki-do 463-830 / KR
07 / KIM, Hyung-Cheol
37, 266 Jungreung-dong, Sungbuk-ku
Seoul 136-100 / KR
 [2008/28]
Former [2002/46]01 / LIM, Kook-Jin
Eunbitmaeul 521-1807, 870 Hwajongdong, Deokyang-ku
Koyang-si, Kyungki-do 412-270 / KR
02 / SHON, Mi-Jin
Hanbit Apt. 125-505, 99 Eoeun-dong, Yoosung-ku
Daejeon-si 305-755 / KR
03 / YOO, Seung-Bum
Hanuri Apt. 104-601, 763, Tanbang-dong, Seo-ku
Daejeon-si 302-768 / KR
04 / LEE, Sang-Ik
Narae Apt. 104-1303, 462-4 Jeonmindong, Yoosung-ku
Daejeon-si 305-811 / KR
05 / OH, Jae-Hoon
Chungsol Apt. 102-306, 8-2 Songangdong, Yoosung-ku
Daejeon-si 305-752 / KR
06 / LEE, Seung-Won
Limaechon 206-1804, 124, Limae-dong, Bundang-ku
Sungnam-si, Kyungki-do 463-830 / KR
07 / KIM, Hyung-Cheol
37, 266 Jungreung-dong, Sungbuk-ku
Seoul 136-100 / KR
Representative(s)Hoffmann Eitle
Patent- und Rechtsanwälte PartmbB
Arabellastrasse 30
81925 München / DE
[N/P]
Former [2002/46]HOFFMANN - EITLE
Patent- und Rechtsanwälte Arabellastrasse 4
81925 München / DE
Application number, filing date01908398.915.02.2001
[2002/46]
WO2001KR00229
Priority number, dateKR2000000764817.02.2000         Original published format: KR 2000007648
KR2000000764917.02.2000         Original published format: KR 2000007649
KR2000000765017.02.2000         Original published format: KR 2000007650
KR2000001217210.03.2000         Original published format: KR 2000012172
KR2000004580608.08.2000         Original published format: KR 2000045806
[2002/46]
Filing languageEN
Procedural languageEN
PublicationType: A1 Application with search report
No.:WO0161032
Date:23.08.2001
Language:EN
[2001/34]
Type: A1 Application with search report 
No.:EP1255852
Date:13.11.2002
Language:EN
The application published by WIPO in one of the EPO official languages on 23.08.2001 takes the place of the publication of the European patent application.
[2002/46]
Type: B1 Patent specification 
No.:EP1255852
Date:10.12.2008
Language:EN
[2008/50]
Type: B9 Corrected patent specification 
No.:EP1255852
Date:15.04.2009
[2009/16]
Search report(s)International search report - published on:KR23.08.2001
(Supplementary) European search report - dispatched on:EP25.11.2004
ClassificationIPC:C12Q1/04, G01N33/53, C12N15/00
[2002/46]
CPC:
G01N33/56905 (EP,US); A61P33/06 (EP); C07K14/445 (EP,US);
G01N2333/445 (EP,US); Y02A50/30 (EP)
Designated contracting statesAT,   BE,   CH,   CY,   DE,   DK,   ES,   FI,   FR,   GB,   GR,   IE,   IT,   LI,   LU,   MC,   NL,   PT,   SE,   TR [2002/46]
Extension statesALNot yet paid
LTNot yet paid
LVNot yet paid
MKNot yet paid
RONot yet paid
SINot yet paid
TitleGerman:IMMUNOASSAY UND DIAGNOSTISCHES REAGENZ FÜR MALARIA[2002/46]
English:IMMUNOASSAY AND DIAGNOSTIC REAGENT FOR MALARIA[2002/46]
French:REACTIF DE DOSAGE IMMUNOLOGIQUE ET DE DIAGNOSTIC POUR LE PALUDISME[2002/46]
Biological materialThis application mentions deposited biological material, check the file for details
Entry into regional phase08.08.2002National basic fee paid 
08.08.2002Search fee paid 
08.08.2002Designation fee(s) paid 
08.08.2002Examination fee paid 
Examination procedure24.08.2001Request for preliminary examination filed
International Preliminary Examining Authority: KR
08.08.2002Amendment by applicant (claims and/or description)
08.08.2002Examination requested  [2002/46]
01.09.2006Despatch of a communication from the examining division (Time limit: M06)
08.02.2007Reply to a communication from the examining division
20.08.2007Despatch of a communication from the examining division (Time limit: M06)
20.02.2008Reply to a communication from the examining division
10.03.2008Despatch of a communication from the examining division (Time limit: M04)
09.04.2008Reply to a communication from the examining division
17.06.2008Communication of intention to grant the patent
15.10.2008Fee for grant paid
15.10.2008Fee for publishing/printing paid
Opposition(s)11.09.2009No opposition filed within time limit [2009/47]
Fees paidRenewal fee
24.02.2003Renewal fee patent year 03
23.02.2004Renewal fee patent year 04
21.02.2005Renewal fee patent year 05
22.02.2006Renewal fee patent year 06
23.02.2007Renewal fee patent year 07
21.02.2008Renewal fee patent year 08
Opt-out from the exclusive  Tooltip
competence of the Unified
Patent Court		 See the Register of the Unified Patent Court for opt-out data
Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court.
Lapses during opposition  TooltipAT10.12.2008
BE10.12.2008
CY10.12.2008
DK10.12.2008
FI10.12.2008
IT10.12.2008
NL10.12.2008
TR10.12.2008
IE15.02.2009
LU15.02.2009
CH28.02.2009
LI28.02.2009
MC28.02.2009
FR02.03.2009
GB10.03.2009
SE10.03.2009
GR11.03.2009
ES21.03.2009
PT11.05.2009
DE01.09.2009
[2011/43]
Former [2011/21]AT10.12.2008
BE10.12.2008
DK10.12.2008
FI10.12.2008
IT10.12.2008
NL10.12.2008
IE15.02.2009
LU15.02.2009
CH28.02.2009
LI28.02.2009
MC28.02.2009
FR02.03.2009
GB10.03.2009
SE10.03.2009
GR11.03.2009
ES21.03.2009
PT11.05.2009
DE01.09.2009
Former [2011/14]AT10.12.2008
BE10.12.2008
DK10.12.2008
FI10.12.2008
IT10.12.2008
NL10.12.2008
IE15.02.2009
CH28.02.2009
LI28.02.2009
MC28.02.2009
FR02.03.2009
GB10.03.2009
SE10.03.2009
GR11.03.2009
ES21.03.2009
PT11.05.2009
DE01.09.2009
Former [2010/47]AT10.12.2008
BE10.12.2008
DK10.12.2008
FI10.12.2008
NL10.12.2008
IE15.02.2009
CH28.02.2009
LI28.02.2009
MC28.02.2009
FR02.03.2009
GB10.03.2009
SE10.03.2009
GR11.03.2009
ES21.03.2009
PT11.05.2009
DE01.09.2009
Former [2010/23]AT10.12.2008
BE10.12.2008
DK10.12.2008
FI10.12.2008
NL10.12.2008
IE15.02.2009
CH28.02.2009
LI28.02.2009
MC28.02.2009
FR02.03.2009
GB10.03.2009
SE10.03.2009
ES21.03.2009
PT11.05.2009
DE01.09.2009
Former [2010/21]AT10.12.2008
BE10.12.2008
DK10.12.2008
FI10.12.2008
NL10.12.2008
IE15.02.2009
CH28.02.2009
LI28.02.2009
MC28.02.2009
FR02.03.2009
SE10.03.2009
ES21.03.2009
PT11.05.2009
DE01.09.2009
Former [2010/09]AT10.12.2008
BE10.12.2008
DK10.12.2008
FI10.12.2008
NL10.12.2008
IE15.02.2009
CH28.02.2009
LI28.02.2009
MC28.02.2009
SE10.03.2009
ES21.03.2009
PT11.05.2009
DE01.09.2009
Former [2010/07]AT10.12.2008
BE10.12.2008
DK10.12.2008
FI10.12.2008
NL10.12.2008
IE15.02.2009
CH28.02.2009
LI28.02.2009
MC28.02.2009
SE10.03.2009
ES21.03.2009
PT11.05.2009
Former [2009/47]AT10.12.2008
BE10.12.2008
DK10.12.2008
FI10.12.2008
NL10.12.2008
CH28.02.2009
LI28.02.2009
MC28.02.2009
SE10.03.2009
ES21.03.2009
PT11.05.2009
Former [2009/46]AT10.12.2008
BE10.12.2008
DK10.12.2008
FI10.12.2008
NL10.12.2008
MC28.02.2009
SE10.03.2009
ES21.03.2009
PT11.05.2009
Former [2009/42]AT10.12.2008
BE10.12.2008
FI10.12.2008
NL10.12.2008
MC28.02.2009
SE10.03.2009
ES21.03.2009
PT11.05.2009
Former [2009/40]AT10.12.2008
BE10.12.2008
FI10.12.2008
NL10.12.2008
SE10.03.2009
ES21.03.2009
PT11.05.2009
Former [2009/37]BE10.12.2008
FI10.12.2008
NL10.12.2008
SE10.03.2009
ES21.03.2009
PT11.05.2009
Former [2009/33]BE10.12.2008
FI10.12.2008
NL10.12.2008
ES21.03.2009
Former [2009/32]BE10.12.2008
FI10.12.2008
NL10.12.2008
Former [2009/25]FI10.12.2008
NL10.12.2008
Documents cited:Search[X]  - SOARES I S ET AL, "LONGEVITY OF NATURALLY ACQUIRED ANTIBODY RESPONSES TO THE N- AND C-TERMINAL REGIONS OF PLASMODIUM VIVAX MEROZOITE SURFACE PROTEIN 1", AMERICAN JOURNAL OF TROPICAL MEDICINE & HYGIENE, LAWRENCE, KS, US, (1999), vol. 60, no. 3, ISSN 0002-9637, pages 357 - 363, XP009028883 [X] 1-15,17,21-35,57,58,60 * abstract * * page 357, column 1, paragraph 1 * * page 358, column 1, paragraphs 2,3 * * figures 3,4 *
 [X]  - TYAGI P ET AL, "NATURALLY OCCURRING PLASMODIA-SPECIFIC CIRCULATING IMMUNE COMPLEXES IN INDIVIDUALS OF MALARIA ENDEMIC AREAS IN INDIA", INDIAN JOURNAL OF MALARIOLOGY, MALARIA RESEARCH CENTER, DEHLI, IN, (199903), vol. 36, no. 1/2, pages 12 - 18, XP009028923 [X] 1-7,13,15,16,21-23,29,31-34 * abstract * * page 13, column 1, paragraph 2 - column 2, paragraph 1 * * page 14, column 2, paragraph 2 - page 15, column 2, paragraph 1 * * page 16, column 1, paragraph 2 - page 17, column 1, paragraph 1 *
 [X]  - RAY K ET AL, "EVALUATION OF INDIRECT IMMUNOFLUORESCENT ANTIBODY TEST FOR DETECTION OF IGM SPECIFIC ANTIBODIES IN MALARIA", JOURNAL OF COMMUNICABLE DISEASES, INDIA SOCIETY FOR MALARIA AND OTHER COMMUNICABLE DISEASES, DEL, IN, (199206), vol. 24, no. 2, ISSN 0019-5138, pages 82 - 86, XP009028938 [X] 1-7,13,15,21-23,29,31-34 * abstract * * page 82, paragraph 1 - page 83, paragraph 4 * * tables 1,2 * * page 85, paragraphs 3-5 *
 [XY]  - GIBSON H L ET AL, "STRUCTURE AND EXPRESSION OF THE GENE FOR PV200 A MAJOR BLOOD-STAGE SURFACE ANTIGEN OF PLASMODIUM-VIVAX", MOLECULAR AND BIOCHEMICAL PARASITOLOGY, (1992), vol. 50, no. 2, ISSN 0166-6851, pages 325 - 334, XP000199300 [X] 47-50 * abstract * * page 326, column 2, paragraph 3 - page 327, column 2, paragraph 1 * [Y] 41-46

DOI:   http://dx.doi.org/10.1016/0166-6851(92)90230-H
 [XY]  - GENTZ R ET AL, "MAJOR SURFACE ANTIGEN P190 OF PLASMODIUM FALCIPARUM: DETECTION OF COMMON EPITOPES PRESENT IN A VARIETY OF PLASMODIA ISOLATES", EMBO JOURNAL, OXFORD UNIVERSITY PRESS, SURREY, GB, (1988), vol. 7, no. 1, ISSN 0261-4189, pages 225 - 230, XP002057622 [X] 57-60 * abstract * * page 226, column 2, paragraph 3 * [Y] 41-46
International search[Y]WO9726911  (UNIV GEORGETOWN [US], et al);
 [Y]WO9730158  (PASTEUR INSTITUT [FR], et al);
 [Y]  - SOARES ET AL., "Acquired immune responses to the N- and C-terminal regions of plasmodium vivax merozoite surface protein 1 in individuals exposed to malaria", INFECT. IMMUN., (1997), vol. 65, pages 1606 - 1614, XP002972558
 [Y]  - PAN ET AL, "Vaccine candidate MSP-1 from plasmodium falciparum: a redesigned 4917 bp polynucleotide enables synthesis and isolation of full-length protein from escherichia coli and mammalian cells", NUCLEIC ACIDS RES., (19990215), vol. 27, pages 1094 - 1103, XP000953100

DOI:   http://dx.doi.org/10.1093/nar/27.4.1094
 [Y]  - FRUH ET AL, "A new tool for the serodiagnosis of acute plasmodium falciparum malaria in individuals with promary infection", J. IMMUNOL. METHODS, (19890815), vol. 122, pages 25 - 32, XP002972559

DOI:   http://dx.doi.org/10.1016/0022-1759(89)90330-X
 [Y]  - SANCHEZ ET AL, "Antibody response to plasmodium vivax antigens in human malaria", AM. J. TROP. MED. HYG., (199403), vol. 50, pages 329 - 338, XP002973046
 [Y]  - SOARES ET AL, "Antibody response to the N and C-terminal regions of the plasmodium vivax merozoite surface protein 1 in individuals living in an area of exclusive transmission of P. vivax malaria in the north of Brazil", ACTA TROP., (19990115), vol. 72, pages 13 - 24, XP002972552

DOI:   http://dx.doi.org/10.1016/S0001-706X(98)00078-3
 [Y]  - MAIER ET AL, "Serodiagnosis of malaria. Plasmodium berghei and P. falciparum as antigen for the indirect immune of fluorescence test", IMMUN. INFECT., (197906), vol. 7, pages 75 - 82, XP002973070
 [Y]  - KASLOW ET AL, "Expression and immunogenicity of the C-terminus of a major blood-stage surface protein of plasmodium vivax, Pv200(19), secreted from saccharomyces cerevisiae", IMMUNOL. LETT., (199607), vol. 51, pages 187 - 189, XP002972560

DOI:   http://dx.doi.org/10.1016/0165-2478(96)02570-9
 [Y]  - KASLOW ET AL, "Expression and antigenicity of plasmodium falciparum major merozoite surface protein (MSP1(19)) variants secreted from saccharomyces cerevisiae", MOL. BIOCHEM. PARASITOL., (1994), vol. 63, pages 283 - 289, XP000603953

DOI:   http://dx.doi.org/10.1016/0166-6851(94)90064-7
 [Y]  - DELCARDAYRE ET AL, "Engineering ribonucleas A: production, purification and characterization of wild-type enzyme and mutants at G1n11", PROTEIN ENG., (1995), vol. 8, pages 261 - 273, XP002972561
 [Y]  - WITZGALL ET AL, "A mammalian expression vector for the expression of GAL4 fusion proteins with an epitope tag and histidine tail", ANAL. BIOMCHEM., (1994), vol. 223, pages 291 - 298, XP002972562

DOI:   http://dx.doi.org/10.1006/abio.1994.1587
 [Y]  - GENBANK, Database accession no. AAC37236, XP002972501
 [Y]  - HUW DAVIES, Introductory immunology, CHAPMAN & HALL, (1997), pages 381 - 383, XP008041000 [Y] * page 381, column 383 *
 [T]  - PARK ET AL, "Naturally acquired antibody responses to the C-terminal region of merozoite surface protein 1 of plasmodium vivax in Korea", CLIN. DIAGN. LAB. IMMUNOL., (2001), vol. 8, pages 14 - 20, XP002972563

DOI:   http://dx.doi.org/10.1128/CDLI.8.1.14-20.2001
by applicant   - ELLINGER ET AL., VIROL., (1991), vol. 180, page 81
    - MARCZINOVITS ET AL., J. BIOCHEM., (1993), vol. 31, page 225
    - CHANG ET AL., BIOTECHNOLOGY, (1985), vol. 3, pages 985 - 990
    - ELLINGER ET AL., VIROLOGY, (1991), vol. 180, pages 811 - 813
    - SOARES ET AL., AMERICAN JOURNAL OF TROPICAL MEDICINE & HYGIENE, (1999), vol. 60, no. 3, pages 357 - 363
    - TYAGI P. ET AL., INDIAN JOURNAL OF MALARIOLOGY, (199903), vol. 36, no. Y2, pages 12 - 18
    - RAY K. ET AL., JOURNAL OF COMMUNICABLE DISEASES, (199206), vol. 24, no. 2, pages 82 - 86
    - GIBSON ET AL., MOLECULAR AND BIOCHEMICAL PARASITOLOGY, (1992), vol. 50, no. 2, pages 325 - 334
    - KASLOW ET AL., IMMUNOL. LETT., (199607), vol. 51, pages 187 - 189
    - GENTZ R. ET AL., EMBO JOURNAL, (1988), vol. 7, no. 1, pages 225 - 230
The EPO accepts no responsibility for the accuracy of data originating from other authorities; in particular, it does not guarantee that it is complete, up to date or fit for specific purposes.