-
EP1280809
European procedure
Extract from the Register of European Patents
EP About this file: EP1280809
| EP1280809 - ANTITUMORAL ECTEINASCIDIN DERIVATIVES [Right-click to bookmark this link] | Status | No opposition filed within time limit Status updated on 12.05.2006 Database last updated on 31.03.2026 | Most recent event Tooltip | 11.07.2008 | Change - representative | published on 13.08.2008 [2008/33] | Applicant(s) | For all designated states PHARMA MAR, S.A. Calle de la Calera 3, Poligono Industrial de Tres Cantos 28760 Tres Cantos Madrid / ES | [N/P] |
| Former [2003/06] | For all designated states PHARMA MAR, S.A. Calle de la Calera 3, Poligono Industrial de Tres Cantos 28760 Tres Cantos, Madrid / ES | Inventor(s) | 01 /
FLORES, Maria, Pharma Mar, S.A. Calle de la Calera 3, Pol. Ind. de Tres Cantos Tres Cantos, E-28760 Madrid / ES | 02 /
FRANCESCH, Andrés, Pharma Mar, S.A. Calle de la Calera, 3, Pol. Ind. de Tres Cantos Tres Cantos, E-28760 Madrid / ES | 03 /
GALLEGO, Pilar, Pharma Mar, S.A. Calle de la Calera, 3, Pol. Ind. de Tres Cantos Tres Cantos, E-28760 Madrid / ES | 04 /
CHICHARRO, José Luis, Pharma Mar, S.A. Calle de laCalera, 3, Pol. Ind. de Tres Cantos Tres Cantos, E-28760 Madrid / ES | 05 /
ZARZUELO, Maria, Pharma Mar, S.A. Calle de la Calera, 3, Pol. Ind. de Tres Cantos Tres Cantos, E-28760 Madrid / ES | 06 /
FERNANDEZ, Carolina, Pharma Mar, S.A. Calle de la Calera, 3, Pol. Ind. de Tres Cantos Tres Cantos, E-28760 Madrid / ES | 07 /
MANZANARES, Ignacio, Pharma Mar, S.A. Calle de la Calera, 3, Pol. Ind. de Tres Cantos Tres Cantos, E-28760 Madrid / ES | [2003/06] | Representative(s) | Ruffles, Graham Keith, et al Marks & Clerk LLP 62-68 Hills Road Cambridge CB2 1LA / GB | [N/P] |
| Former [2008/33] | Ruffles, Graham Keith, et al Marks & Clerk 62-68 Hills Road Cambridge CB2 1LA / GB | ||
| Former [2004/01] | Ruffles, Graham Keith, et al Marks & Clerk, 66-68 Hills Road Cambridge, Cambridgeshire CB2 1LA / GB | ||
| Former [2003/06] | Ruffles, Graham Keith, et al MARKS & CLERK, 57-60 Lincoln's Inn Fields London WC2A 3LS / GB | Application number, filing date | 01919669.0 | 12.04.2001 | [2003/06] | WO2001GB01667 | Priority number, date | GB20000009043 | 12.04.2000 Original published format: GB 0009043 | WO2000GB01852 | 15.05.2000 Original published format: PCT/GB00/01852 | GB20000022644 | 14.09.2000 Original published format: GB 0022644 | [2003/06] | Filing language | EN | Procedural language | EN | Publication | Type: | A1 Application with search report | No.: | WO0177115 | Date: | 18.10.2001 | Language: | EN | [2001/42] | Type: | A1 Application with search report | No.: | EP1280809 | Date: | 05.02.2003 | Language: | EN | The application published by WIPO in one of the EPO official languages on 18.10.2001 takes the place of the publication of the European patent application. | [2003/06] | Type: | B1 Patent specification | No.: | EP1280809 | Date: | 06.07.2005 | Language: | EN | [2005/27] | Search report(s) | International search report - published on: | EP | 18.10.2001 | Classification | IPC: | C07D515/22, A61K35/00, A61K35/56, // (C07D515/22, 317:00, 291:00, 241:00), C07D221:00 | [2003/06] | CPC: |
C07D515/22 (EP,KR,US);
A61K31/4985 (KR);
A61P35/00 (EP,KR);
A61P43/00 (EP)
| Designated contracting states | AT, BE, CH, CY, DE, DK, ES, FI, FR, GB, GR, IE, IT, LI, LU, MC, NL, PT, SE, TR [2003/06] | Extension states | AL | 24.09.2002 | LT | 24.09.2002 | LV | 24.09.2002 | MK | 24.09.2002 | RO | 24.09.2002 | SI | 24.09.2002 | Title | German: | ECTEINASCHIDIN DERIVATE MIT ANTIKREBS WIRKUNG | [2003/06] | English: | ANTITUMORAL ECTEINASCIDIN DERIVATIVES | [2003/06] | French: | DERIVES ANTITUMORAUX D'ECTEINASCIDINES | [2003/06] | Entry into regional phase | 24.09.2002 | National basic fee paid | 24.09.2002 | Designation fee(s) paid | 24.09.2002 | Examination fee paid | Examination procedure | 06.11.2001 | Request for preliminary examination filed International Preliminary Examining Authority: EP | 25.09.2002 | Examination requested [2003/06] | 17.02.2003 | Despatch of a communication from the examining division (Time limit: M06) | 26.08.2003 | Reply to a communication from the examining division | 20.01.2004 | Communication of intention to grant the patent | 20.07.2004 | Fee for grant paid | 20.07.2004 | Fee for publishing/printing paid | Opposition(s) | 07.04.2006 | No opposition filed within time limit [2006/24] | Fees paid | Renewal fee | 14.04.2003 | Renewal fee patent year 03 | 15.04.2004 | Renewal fee patent year 04 | 13.04.2005 | Renewal fee patent year 05 |
| Opt-out from the exclusive Tooltip competence of the Unified Patent Court | See the Register of the Unified Patent Court for opt-out data | ||
| Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court. | Cited in | International search | [X] E.J.COREY,DAVID Y.GIN, AND ROBERT S. KANIA: "Enantioselective Total Synthesis of Ecteinascidin", J.AM.CHEM.SOC., vol. 118, 1996, pages 9202 - 9203, XP002925428 [X] 1,7 * page 203; examples 14,15; table 1A * DOI: http://dx.doi.org/10.1021/ja962480t | [X] RYUICHI SAKAI ET AL.: "Ecteinascidins: Putative Biosynthetic Precursors and Absolute Stereochemistry", J.AM.CHEM.SOC., vol. 118, 1996, pages 9017 - 9023, XP002925426 [X] 1,7 * page 9023, column L, paragraph 1; examples 1-4 * DOI: http://dx.doi.org/10.1021/ja950054m | [A] FUKUYAMA, LIHU YANG, KAREN L.AJECK: "Total Synthesis of(+)-Saframycic", J.AM.CHEM.SOC.,, vol. 112, 1990, pages 3713 - 3715, XP002925425 [A] 1,9 * the whole document * DOI: http://dx.doi.org/10.1021/ja00165a095 | [A] THORU FUKUYAMA ET AL.: "Stereocontrolled Total Synthesis of Saframycic B", J.AM.CHEM.SOC., vol. 104, 1982, pages 4957 - 4958, XP002925427 [A] 1,9 * the whole document * DOI: http://dx.doi.org/10.1021/ja00382a042 | [A] J.W.LOWN, ALUMMOOTTIL V.JOSHUA ET AL.: "Molecular Mechanisms of Binding and Single-Strand Scission of Deoxyribonucleic Acid by the Antitumor Antibiotics saframycic A and C", BIOCHEMISTRY, vol. 21, no. 3, 1982, XP002925424 [A] 1,9 * the whole document * DOI: http://dx.doi.org/10.1021/bi00532a001 |