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Extract from the Register of European Patents

EP About this file: EP1586571

EP1586571 - Dipeptidyl peptidase inhibitors [Right-click to bookmark this link]
StatusThe patent has been limited
Status updated on  22.05.2015
Database last updated on 31.03.2026
Most recent event   Tooltip22.05.2015(Expected) limited patent specificationpublished on 24.06.2015  [2015/26]
Applicant(s)For all designated states
Takeda Pharmaceutical Company Limited
1-1, Doshomachi 4-chome Chuo-ku Osaka-shi
Osaka 541-0045 / JP
[2015/26]
Former [2006/18]For all designated states
Takeda Pharmaceutical Company Limited
1-1, Doshomachi 4-chome Chuo-ku Osaka-shi
Osaka 541-0045 / JP
Former [2005/42]For all designated states
Takeda San Diego, Inc.
10410 Science Center Drive
San Diego CA 92121 / US
Inventor(s)01 / Feng, Jun
3536 Corte Yolanda
Carlsbad, CA 92009 / US
02 / Gwaltney, II, Stephen, L.
2620 Canyon Road
Escondido, CA 92025 / US
03 / Stafford, Jeffrey A.
12752 Sandy Crest Court
San Diego, CA 92130 / US
04 / Zhang, Zhiyuan
3775 Carmel View Road, 2
San Diego, CA 92130 / US
05 / ELDER, Bruce J. c/o Albany Molecular Research Inc.
21 Corporate Circle
Albany, New York 12212 / US
06 / ISBESTER, Paul K. c/o Albany Molecular Research Inc.
21 Corporate Circle
Albany, New York 12212 / US
07 / PALMER, Grant J. c/o Albany Molecular Research Inc.
21 Corporate Circle
Albany, New York 12212 / US
08 / SALSBURY, Jonathon S. c/o Albany Molecular Research Inc.
21 Corporate Circle
Albany, New York 12212 / US
09 / ULYSEE, Luckner G. c/o Albany Molecular Research Inc.
21 Corporate Circle
Albany, New York 12212 / US
 [2015/26]
Former [2007/32]01 / Feng, Jun
3536 Corte Yolanda
Carlsbad, CA 92009 / US
02 / Gwaltney, II, Stephen, L.
2620 Canyon Road
Escondido, CA 92025 / US
03 / Stafford, Jeffrey A.
12752 Sandy Crest Court
San Diego, CA 92130 / US
04 / Zhang, Zhiyuan
3775 Carmel View Road, 2
San Diego, CA 92130 / US
05 / ELDER, Bruce J. c/o Albany Molecular Research Inc.
21 Corporate Circle
Albany, New York 12212 / US
06 / ISBESTER, Paul K. c/o Albany Molecular Research Inc.
21 Corporate Circle
Albany, New York 12212 / US
07 / PALMER, Grant J. c/o Albany Molecular Research Inc.
21 Corporate Circle
Albany, New York 12212 / US
08 / SALSBURY, Jonathon S. c/o Albany Molecular Research Inc.
21 Corporate Circle
Albany, New York 12212 / US
09 / ULYSEE, Luckner G. c/o Albany Molecular Research Inc.
21 Corporate Circle
Albany, New York 12212 / US
Former [2007/23]01 / Feng, Jun
3536 Corte Yolanda
Carlsbad, CA 92009 / US
02 / Gwaltney, II, Stephen, L.
12246 Dormhouse Road
San Diego, CA 92129 / US
03 / Stafford, Jeffrey A.
12752 Sandy Crest Court
San Diego, CA 92130 / US
04 / Zhang, Zhiyuan
3775 Carmel View Road, 2
San Diego, CA 92130 / US
05 / ELDER, Bruce J. c/o Albany Molecular Research Inc.
21 Corporate Circle
Albany, New York 12212 / US
06 / ISBESTER, Paul K. c/o Albany Molecular Research Inc.
21 Corporate Circle
Albany, New York 12212 / US
07 / PALMER, Grant J. c/o Albany Molecular Research Inc.
21 Corporate Circle
Albany, New York 12212 / US
08 / SALSBURY, Jonathon S. c/o Albany Molecular Research Inc.
21 Corporate Circle
Albany, New York 12212 / US
09 / ULYSEE, Luckner G. c/o Albany Molecular Research Inc.
21 Corporate Circle
Albany, New York 12212 / US
Former [2005/42]01 / Feng, Jun
3536 Corte Yolanda
Carlsbad, CA 92009 / US
02 / Gwaltney, II, Stephen, L.
12246 Dormhouse Road
San Diego, CA 92129 / US
03 / Stafford, Jeffrey A.
12752 Sandy Crest Court
San Diego, CA 92130 / US
04 / Zhang, Zhiyuan
3775 Carmel View Road, 2
San Diego, CA 92130 / US
Representative(s)Duncan, Garreth Andrew, et al
D Young & Co LLP
120 Holborn
London EC1N 2DY / GB
[2015/26]
Former [2005/42]Nachshen, Neil Jacob, et al
D Young & Co 120 Holborn
London EC1N 2DY / GB
Application number, filing date04258153.821.12.2004
[2005/42]
Priority number, dateUS20040553571P15.03.2004         Original published format: US 553571 P
US20040629524P18.11.2004         Original published format: US 629524 P
[2005/42]
Filing languageEN
Procedural languageEN
PublicationType: A1 Application with search report 
No.:EP1586571
Date:19.10.2005
Language:EN
[2005/42]
Type: B1 Patent specification 
No.:EP1586571
Date:16.07.2008
Language:EN
[2008/29]
Type: B3 Limited patent 
No.:EP1586571
Date:24.06.2015
Language:EN
[2015/26]
Search report(s)(Supplementary) European search report - dispatched on:EP14.06.2005
ClassificationIPC:C07D401/04, C07D401/12, C07D401/14, A61K31/506, A61P3/10, A61P35/00
[2005/42]
CPC:
C07D403/04 (EP,US); C07D401/04 (EP,KR,US); A61P13/08 (EP);
A61P13/12 (EP); A61P15/08 (EP); A61P15/16 (EP);
A61P15/18 (EP); A61P17/06 (EP); A61P19/02 (EP);
A61P19/10 (EP); A61P25/28 (EP); A61P29/00 (EP);
A61P3/10 (EP); A61P31/18 (EP); A61P35/00 (EP);
A61P35/04 (EP); A61P37/02 (EP); A61P37/04 (EP);
A61P37/06 (EP); A61P39/02 (EP); A61P5/02 (EP);
A61P7/06 (EP); C07D239/545 (EP,US); C07D401/12 (KR);
C07D401/14 (EP,KR,US); C07D403/12 (EP,US); C07D409/14 (EP,US) (-)
Designated contracting statesAT,   BE,   BG,   CH,   CY,   CZ,   DE,   DK,   EE,   ES,   FI,   FR,   GB,   GR,   HU,   IE,   IS,   IT,   LI,   LT,   LU,   MC,   NL,   PL,   PT,   RO,   SE,   SI,   SK,   TR [2015/26]
Former [2005/42]AT,  BE,  BG,  CH,  CY,  CZ,  DE,  DK,  EE,  ES,  FI,  FR,  GB,  GR,  HU,  IE,  IS,  IT,  LI,  LT,  LU,  MC,  NL,  PL,  PT,  RO,  SE,  SI,  SK,  TR 
Extension statesAL19.01.2005
BA19.01.2005
HR19.01.2005
LV19.01.2005
MK19.01.2005
YU19.01.2005
TitleGerman:DIPEPTIDYL PEPTIDASE HEMMSTOFFE[2015/26]
English:Dipeptidyl peptidase inhibitors[2005/42]
French:Inhibiteurs de dipeptidyl peptidase[2005/42]
Former [2005/42]Dipeptidyl peptidase Hemmstoffe
Examination procedure19.01.2005Examination requested  [2005/42]
23.12.2005Despatch of a communication from the examining division (Time limit: M04)
03.05.2006Reply to a communication from the examining division
04.08.2006Despatch of a communication from the examining division (Time limit: M04)
04.12.2006Reply to a communication from the examining division
03.04.2007Despatch of a communication from the examining division (Time limit: M04)
14.06.2007Reply to a communication from the examining division
25.01.2008Communication of intention to grant the patent
27.05.2008Fee for grant paid
27.05.2008Fee for publishing/printing paid
Opposition(s)17.04.2009No opposition filed within time limit [2009/26]
Limitations:14.08.2014Date of receipt of request for limitation
 admissible
13.02.2015Communication of intention to limit the patent
13.05.2015Fee for printing patent specification after limitation
23.10.2014Despatch of a communication from the examining division (Time limit: M02)
16.12.2014Reply to a communication from the examining division
Request for further processing for:03.05.2006Request for further processing filed
03.05.2006Full payment received (date of receipt of payment)
Request granted
18.05.2006Decision despatched
Fees paidRenewal fee
27.12.2006Renewal fee patent year 03
24.12.2007Renewal fee patent year 04
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Documents cited:Search[A] WO03035057  (FERRING BV et al.) [A] 1-145 * the whole document *
 [X] JP2003300977  
 [X] DE2150686  (BASF AG et al.) [X] 1-145 * claim 1 *
 [X] EP0442473  (TAKEDA CHEMICAL INDUSTRIES LTD et al.) [X] 1-145 * tables 1a-4a,5 *
 [PA]   WEBER, A.E.: "DIPEPTIDYL PEPTIDASE IV INHIBITORS FOR THE TREATMENT OF DIABETES", JOURNAL OF MEDICINAL CHEMISTRY, vol. 47, 2004, pages 4135 - 4141, XP002329845 [PA] 1-145 * figure 2 *

DOI:   http://dx.doi.org/10.1021/jm030628v
 [X]   PATENT ABSTRACTS OF JAPAN vol. 2003, no. 12 5 December 2003 (2003-12-05) [X] 1-145 * abstract *
 [X]   BOTTA, M., SALADINO, R., LAMBA, D., NICOLETTI, R.: "Researches on Antiviral Agents. 31. Synthesis and Transformations of Racemic and Chiral 6-Oxiranyl Pyrimidinones", TETRAHEDRON, vol. 49, 1993, pages 6053 - 6070, XP002329846 [X] 1 * examples 3,6 *

DOI:   http://dx.doi.org/10.1016/S0040-4020(01)87190-8
 [X]   FRAISSE, L. ET AL.: "Long-Chain-Substituted Uric Acid and 5,6-Diaminouracil Derivatives as Novel Agents against Free Radical Processes: Synthesis and in Vitro Activity", JOURNAL OF MEDICINAL CHEMISTRY, vol. 36, 1993, pages 1465 - 1473, XP002329847 [X] 1 * example 4k *

DOI:   http://dx.doi.org/10.1021/jm00062a020
 [X]   KIM, H.O. ET AL.: "Structure-Activity Relationships of 1,3-Dialkylxanthine Derivatives at Rat A3 adenosine Receptors", JOURNAL OF MEDICINAL CHEMISTRY, vol. 37, 1994, pages 3373 - 3382, XP002329848 [X] 1 * example 38b *

DOI:   http://dx.doi.org/10.1021/jm00046a022
The EPO accepts no responsibility for the accuracy of data originating from other authorities; in particular, it does not guarantee that it is complete, up to date or fit for specific purposes.